Actinomyces sp. 432: CWT12_03740
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Entry
CWT12_03740 CDS
T06433
Symbol
leuD
Name
(GenBank) 3-isopropylmalate dehydratase small subunit
KO
K01704
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
actz
Actinomyces sp. 432
Pathway
actz00290
Valine, leucine and isoleucine biosynthesis
actz00660
C5-Branched dibasic acid metabolism
actz01100
Metabolic pathways
actz01110
Biosynthesis of secondary metabolites
actz01210
2-Oxocarboxylic acid metabolism
actz01230
Biosynthesis of amino acids
Module
actz_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
actz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
CWT12_03740 (leuD)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CWT12_03740 (leuD)
Enzymes [BR:
actz01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
CWT12_03740 (leuD)
4.2.1.35 (R)-2-methylmalate dehydratase
CWT12_03740 (leuD)
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Paralog
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Motif
Pfam:
Aconitase_C
LeuD
LeuD_C
IgGFc_binding
Motif
Other DBs
NCBI-ProteinID:
QHO90626
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Position
918877..919560
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AA seq
227 aa
AA seq
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MEKFIRHTGIGAPLRRSAVDTDQIIPAVYLKRITRTGFEDALFASWRASEADFILNQEAY
KRASVLVAGPDFGTGSSREHAVWALKDYGFKVVLAPRFADIFRGNAGKQGLVAGVISQED
TEQLWKILETEPGTEITVDLEQRTVEAGSFRTVFQIDDYVRWTLMEGLDDISLTLTHEEA
IRAYEDARPAYKPRTLPARHEPAVAVAPARSAEMPVPIGYPFLRPGA
NT seq
684 nt
NT seq
+upstream
nt +downstream
nt
atggagaagttcatccgccacaccggcatcggcgcccccctgcgccgcagcgcggtggac
accgaccagatcatcccggccgtctacctcaagcgcattacccgcaccggcttcgaggac
gccctgttcgcctcctggcgggcgagcgaggccgatttcatcctcaaccaggaggcctac
aagcgggccagcgtgctggtggccggccccgacttcggcaccggatcctcccgcgagcac
gccgtgtgggcgctgaaggactatggcttcaaggtggtgctcgcaccccgcttcgccgac
atcttccgcggcaacgcgggcaagcagggactggtagccggggtcatcagccaggaggac
accgagcagctgtggaagatcctggagaccgagcccggcaccgagatcaccgtggacctg
gagcagcgcaccgtcgaggcgggctccttccgcaccgtgttccagatcgacgactatgtg
cgctggacccttatggaggggctggatgacatctcgctcaccctcacccacgaggaggcc
atccgcgcgtacgaggatgcccggcccgcctataagccgcggactctgccggcccgccac
gagccggctgtagccgtcgcccctgcccggtcagcggagatgcccgtgcctatcggctat
cccttcctgcgcccgggagcgtga
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