Amycolatopsis cynarae: ORV05_03010
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Entry
ORV05_03010 CDS
T09969
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
acyn
Amycolatopsis cynarae
Pathway
acyn00020
Citrate cycle (TCA cycle)
acyn00630
Glyoxylate and dicarboxylate metabolism
acyn00785
Lipoic acid metabolism
acyn01100
Metabolic pathways
acyn01110
Biosynthesis of secondary metabolites
acyn01120
Microbial metabolism in diverse environments
acyn01200
Carbon metabolism
acyn01210
2-Oxocarboxylic acid metabolism
Module
acyn_M00009
Citrate cycle (TCA cycle, Krebs cycle)
acyn_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
acyn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
ORV05_03010
00630 Glyoxylate and dicarboxylate metabolism
ORV05_03010
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ORV05_03010
Enzymes [BR:
acyn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
ORV05_03010
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
ORV05_03010
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
ORV05_03010
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
ORV05_03010
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
WAL66797
LinkDB
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Position
complement(623563..627252)
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AA seq
1229 aa
AA seq
DB search
MSSSSPASQFGPNEWLVEEMYDQFLADPSSVDAAWHDFFSDFKPTQAPAAKPEGAGTAGQ
ATTTAPAPRPSNGQALATTSPPAKQAAATPAPPAAAKPRPASAKPAATAAAKAGEPETKQ
LRGAAAAIAKNMDASLSVPTATSVRAVPAKLMADNRIVINNHLKRTRGGKISFTHLIGYA
MVRALRDFPNMNRHYELIEGKPFAVTPEHVNLGLAIDMKGKDGSRTLVVASIKNTENMSF
LQFWQAYEEIVKKARNNKLTADDFSGTTISLTNPGGIGTNHSVPRLQAGQGAIIGVGAMQ
YPAHFEGTSEKTLVDLGVSKIMTLTSTYDHRIIQGAESGEFLKRIHELLLGGDGFYDDIF
TSLRLPYEPIRWVEDIPEGGIDKTARVLELIDAYRMRGHLMADTDPLNYRQRRHEDLDVL
SHGLTLWDLDREFAVGGFAGKERMKLRDVLGVLRDSYCRTVGVEYTHILDPDERRWIQER
VEVPHAKPDQAVQKYILSKLNAAEAFETFLQTKYVGQKRFSLEGGETVIPLLDTVLDKAA
EHELDEVVIGMPHRGRLNVLANIVGKPISQIFQEFEGNLDPGQAHGSGDVKYHLGAEGKY
FRMFGDGETKVSLTANPSHLETVDPVLEGIVRAKQDILDKGGDSGGFTVLPVLLHGDAAF
AGQGVVAETLNLALLRGYRTGGTVHIIINNQVGFTTAPENSRSSQYATDVAKMIGAPIFH
VNGDDPEAAHWVAKLAVEYRQAFNKDVVIDMICYRRRGHNEGDDPSMTQPAMYDIIDTKR
SVRKTYTESLIGRGDISVEEAEAALRDFSSQLEHVFNEVRELEKHPITPSPSVEEEQQVP
AKVPTAVPRETIEHIGDSFLNVPDGFNPHPRVKPVLERRAKMAREGGIDWAFGELLAFGS
LAMEGRLVRLSGQDSRRGTFTQRHSVLIDRKNGREYAPLQNLGEDQGRVMIYDSALSEYA
AVGFEYGYSVANSDALVLWEAQFGDFVNGAQTVIDEYISSGEAKWGQRSDLVLLLPHGHE
GQGPDHTSGRIERFLQLCAESSMTVAVPSTPANYFHLLRRHALDGIQRPLIVFTPKSMLR
NKAATSMVEDFIGQTKFMSVIDDVEVDPAKVRKVLLTSGKLYWELVAERAKRGADDVAIV
RIEQYYPLPMKKLRAALERYTASPQVAWVQEEPENQGGWPFFGLHLPRKFPELLSGLDVV
ARRPMAAPSAGSSKVHDVEQKALIAKAFS
NT seq
3690 nt
NT seq
+upstream
nt +downstream
nt
gtgtccagcagcagccctgcgtcacagttcggccccaacgaatggctcgtcgaggagatg
tacgaccagttcctcgccgacccttcttcagtagatgccgcttggcatgacttcttctcc
gacttcaagccgacccaggctccggcggcgaagccggaaggcgcaggcaccgcaggccag
gccaccaccacggccccggccccgcgaccgagcaacgggcaggccctcgcgaccacctcg
ccgccggccaagcaggccgccgcgaccccggctccaccggctgccgcgaagccccggccg
gccagcgccaagcccgccgccaccgcggccgccaaggcaggcgagccggagaccaagcag
ctgcgcggcgcggccgccgcgatcgccaagaacatggacgcctcgctgagcgtgccgacc
gcgaccagcgtccgcgcggtgcccgccaagctgatggccgacaaccgcatcgtcatcaac
aaccacctcaagcgcacccgcggcgggaagatctccttcacgcacctcatcgggtacgcg
atggtccgtgcgctgcgcgacttcccgaacatgaaccggcactacgagctgatcgaaggc
aagcccttcgcggtcacgccggaacacgtcaacctcggcctcgccatcgacatgaagggc
aaggacggcagccgcaccctcgtcgtcgcctccatcaagaacacggagaacatgtcgttc
ctccagttctggcaggcctacgaggagatcgtcaagaaggcccgcaacaacaagctcacc
gcggacgacttctccggcaccaccatctcgctgaccaacccgggcggcatcggcaccaac
cactcggtgccgcggctgcaggcgggccagggcgcgatcatcggtgtgggtgccatgcag
taccccgcgcatttcgagggcaccagtgagaagacgctggtcgacctgggcgtcagcaag
atcatgacgctgacctcgacctatgaccaccggatcatccagggggcggagtccggagag
ttcctcaagcgcatccacgagctgctgctcggcggcgacggcttctacgacgacatcttc
acctccctgcggctgccctacgagccgatccgctgggtggaggacattcccgagggcggg
atcgacaagaccgcccgggtgctcgagctgatcgacgcctaccggatgcgcggccacctg
atggccgacaccgacccgctgaactaccgccagcgccgccacgaggacctcgacgtcctc
tcccacggcctgaccctgtgggacctcgaccgcgagttcgccgtcggcggcttcgccggc
aaggagcggatgaagctgcgcgacgtgctgggcgtgctgcgggactcctactgccgcacg
gtgggcgtcgagtacacccacatcctggacccggacgagcgccggtggatccaggagcgc
gtcgaggtgccgcacgccaagcccgaccaggccgtgcagaagtacatcctgtcgaagctc
aacgcggccgaggcgttcgaaaccttcctgcagaccaagtacgtcggccagaagcggttc
tcgctggagggcggcgagacggtgatcccgctgctggacaccgtgctggacaaggccgcc
gaacacgagctcgacgaggtcgtcatcggcatgccgcaccgcggcaggctcaacgtgctg
gccaacatcgtcggcaagccgatctcgcagatcttccaggagttcgagggcaacctcgac
ccgggccaggcccacggctccggtgacgtcaagtaccacctgggcgccgagggcaagtac
ttccggatgttcggcgacggcgagacgaaggtgtcgctgaccgcgaacccgtcccacctg
gagacggtggacccggtgctggagggcatcgtccgcgccaagcaggacatcctcgacaag
ggcggcgactccggcggcttcacggtgctgccggtgctgctgcacggcgacgcggccttc
gcgggccagggtgtcgtggcggagacgctgaacctggcgctgctgcgcggctaccgcacc
ggtggcaccgtgcacatcatcatcaacaaccaggtcggtttcaccaccgcgccggagaac
tcgcgctcctcgcagtacgccaccgacgtggcgaagatgatcggcgcgccgatcttccac
gtcaacggcgacgacccggaggccgcgcactgggtggccaagctggccgtggaataccgc
caggcgttcaacaaggacgtcgtgatcgacatgatctgctaccggcggcgcgggcacaac
gagggcgacgacccgtcgatgacccagccggcgatgtacgacatcatcgacacgaagcgt
tcggtgcggaagacctacaccgaatcgctgatcggccgcggcgacatctcggtggaagag
gccgaggccgcgctgcgggacttctccagccagttggagcacgtcttcaacgaggtccgg
gaactggagaagcacccgatcacgccgagcccgtccgtcgaggaggagcagcaggtcccg
gccaaggtgccgaccgcggtgccgcgcgagaccatcgagcacatcggcgactccttcctc
aacgtgcccgacggcttcaacccgcacccgcgcgtcaagccggtgctggagcgccgcgcg
aagatggcgcgcgaaggcggcatcgactgggcgttcggcgagctgctcgcgttcggttcg
ctggcgatggagggcaggctggtccggctgtccggtcaggactcccgccgcggcaccttc
acccagcggcactcggtgctcatcgaccgcaagaacggccgtgagtacgccccgctgcag
aacctcggcgaggaccagggccgggtgatgatctacgactcggcgctgtcggagtacgcg
gcggtcggcttcgagtacggctactcggtggccaactcggacgcgctggtcctgtgggag
gcgcagttcggcgacttcgtcaacggcgcgcagaccgtcatcgacgagtacatctcctcc
ggtgaggccaagtgggggcagcgctccgacctggtgctgctgctgccgcacggtcacgag
ggtcagggcccggaccacacctcgggccggatcgagcggttcctgcagctgtgcgcggag
agctcgatgacggtcgcggtgccctccaccccggcgaactacttccacctgctgcgccgg
cacgcgctggacggcatccagcgcccgctgatcgtcttcaccccgaagtcgatgctgcgg
aacaaggcggccacctccatggtcgaggacttcatcggccagacgaagttcatgtccgtg
atcgacgacgtcgaggtggacccggcgaaggtccgcaaggtgctgctgacctccggcaag
ctgtactgggagctggtggccgagcgggccaagcggggcgccgacgacgtggcgatcgtg
cggatcgagcagtactacccgctgccgatgaagaagctgcgggccgcgctcgagcgctac
accgcttcgccgcaggtggcctgggtgcaggaagagccggagaaccagggcggctggccg
ttcttcggcctgcacctgccgcggaagttcccggagctgctgtccggtctggacgtggtg
gcacgccgcccgatggcggccccgtccgccggttcgtccaaggtgcacgacgtcgagcag
aaggcgctgatcgccaaggcgttcagctga
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