Amycolatopsis cynarae: ORV05_05305
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Entry
ORV05_05305 CDS
T09969
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
acyn
Amycolatopsis cynarae
Pathway
acyn00010
Glycolysis / Gluconeogenesis
acyn00020
Citrate cycle (TCA cycle)
acyn00620
Pyruvate metabolism
acyn00785
Lipoic acid metabolism
acyn01100
Metabolic pathways
acyn01110
Biosynthesis of secondary metabolites
acyn01120
Microbial metabolism in diverse environments
acyn01200
Carbon metabolism
acyn01210
2-Oxocarboxylic acid metabolism
Module
acyn_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
acyn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
ORV05_05305 (aceE)
00020 Citrate cycle (TCA cycle)
ORV05_05305 (aceE)
00620 Pyruvate metabolism
ORV05_05305 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ORV05_05305 (aceE)
Enzymes [BR:
acyn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
ORV05_05305 (aceE)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
WAL67207
UniProt:
A0ABY7B7G7
LinkDB
All DBs
Position
complement(1085927..1088737)
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AA seq
936 aa
AA seq
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MAPQNDQAARPGTAARQAPARVRVIRDGMAAYLPDIDPEETAEWLDSFDEALARGGQQRA
RYLMLRILERARERNIGVPPLTATDYVNTIPTENEPWFPGDEEIERRYRAYIRWNAAIMV
HRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKDHSGGGDQLYIQGHASPGIYARAFL
EGRLTESQLDGFRQELSHAGAGGGLPSYPHPRLMADFWEYPTVSMGLGPMNAIYQARFNR
YLHDRGIKDTSDQHVWAFLGDGEMDEPESRGLIHVAAGEGLDNLTFVINCNLQRLDGPVR
GNGKIIQELEAYFRGAGWNVIKVIWGREWDALLHGDRDGALVNLMNQTPDGDYQTYKAND
GAYVREHFFGRDPRTKALVKDLSDAEIWNLKRGGHDYRKVYAAYKAAMEHHGQPTVILAH
TIKGYGLGPAFEGRNATHQMKKLTLDDLKLFRDVQRIPISDAELERNPKVPPYYHPGRNS
PEIEYMIGRRRALGGFLPERRASRAKPLVLPGDKVYEAVRKGSGKQEVATTMAFVRLVRE
LAKDAEIGQRIVPIIPDEARTFGLDSMFPTAKIYNPHGQTYTSVDANLMLAYKESEHGQL
LHEGINEAGSTASFTAVGTSYATHGEPMIPIYIFYSMFGFQRTGDGLYAAADQMARGFVL
GATAGRTTLTGEGLQHADGHSLLLAHTNPAAVAYDPAWSFEIAHIVRDGLRRMYGEGGPD
GNGDDVFYYLTVYNEPYQQPAEPENLDVDGLLRGLYRYAEAPAGDGPQAQILVSGVTMPD
ALKAQRMLAEDWGVRAAVWSATSWSELRREAVEVDRDNLLHPADPPRVPYVTQALSGVPG
PVVAASDWMRAVPDLIRPWVPTEMVTLGTDGFGFSDTRPAARRHFLVDAESITVATLAAL
AGRGEVEQAKVVEAARKYRINDVSAAGPQLSDSGNA
NT seq
2811 nt
NT seq
+upstream
nt +downstream
nt
ttggccccccagaacgaccaggccgcacgtccgggcaccgctgcccggcaggcgccggcg
cgggttcgcgtcatccgagacgggatggctgcgtacctgcccgacatcgacccggaggag
accgccgagtggctcgactccttcgacgaggcgctcgcccgcggcggacagcagcgggcg
cgctacctgatgctgcggatcctggaacgtgctcgtgaacgcaacatcggcgtcccgccg
ctgaccgcgacggactacgtcaacaccatccccaccgagaacgaaccctggttccccggt
gacgaagagatcgaacgccgctaccgggcctacatccgctggaacgcggcgatcatggtg
caccgcgcccagcggcccggcgtcggcgtgggcgggcacatctcgacctacgcgtcttcg
gccgcgctctacgaggtggggttcaaccacttcttccgcggcaaggaccactccggcggc
ggcgaccagctgtacatccaggggcacgcctccccgggtatctacgcccgcgccttcctg
gagggcaggctcaccgagtcccagctcgacgggttccggcaggagctctcgcacgccggc
gcgggcggcgggctgccctcgtacccgcacccgcggctgatggcggacttctgggagtac
cccacggtctccatgggcctcggcccgatgaacgccatctaccaggcccggttcaaccgc
tacctgcacgaccggggcatcaaggacaccagcgaccagcacgtctgggcgttcctcggc
gacggcgagatggacgagcccgagtcgcgcggcctgatccacgtcgccgcgggcgaaggc
ctggacaacctgacctttgtgatcaactgcaacctgcagcggctggacgggccggtccgc
ggcaacggtaagatcatccaggagctggaggcgtacttccgcggcgcgggctggaacgtc
atcaaggtcatctggggccgcgagtgggacgcgctgctccacggcgaccgcgacggcgcg
ctggtcaacctgatgaaccagacgccggacggcgactaccagacctacaaggccaacgac
ggcgcctacgtccgcgagcacttcttcggccgtgacccgcgcacgaaggccctggtcaag
gacctcagcgacgccgagatctggaacctcaagcgcggtggccacgactaccgcaaggtg
tacgcggcgtacaaggcggcgatggagcaccacggccagccgaccgtgatcctggcccac
accatcaagggctacggcctcggcccggcgttcgagggccgcaacgccacgcaccagatg
aagaagctcaccctcgacgatctgaaactgttccgggacgtccagcgcatcccgatcagc
gatgccgagctcgagcgcaacccgaaggtgccgccgtactaccacccgggccggaactcg
cccgagatcgagtacatgatcggccgccgccgggcgctgggcgggttcctgccggagcgc
cgcgcgagccgggccaagccactggtgctgcccggtgacaaggtctacgaggcggtccgc
aagggctcgggcaagcaggaggtcgccaccaccatggcgttcgtccggctggtccgcgag
ctggccaaggacgccgagatcgggcagcggatcgtgccgatcatcccggacgaggcgcgc
accttcggcctcgactcgatgttccccacggccaagatctacaacccgcacgggcagacc
tacacctcggtcgacgcgaacctgatgctggcgtacaaggagtccgagcacggccagctg
ctgcacgagggcatcaacgaggccgggtccaccgcctcgttcaccgccgtcggcacgtcc
tacgccacgcatggcgagccgatgatcccgatctacatcttctactcgatgttcgggttc
cagcgcaccggcgacgggctgtacgcggcggccgaccagatggcgcgcgggttcgtgctc
ggcgccaccgcgggccgcaccacgctgaccggtgaagggctccagcacgccgacgggcac
tcgctgctgctcgcgcacaccaacccggcggcggtcgcctacgacccggcgtggtcgttc
gagatcgcccacatcgtgcgggacggcctgcggcgcatgtacggcgagggcggcccggac
ggcaacggtgacgacgtcttctactacctcaccgtgtacaacgagccgtaccagcagccg
gccgagccggagaacctcgacgtggacgggctgctgcgcggcctgtaccgctacgccgag
gcgcccgccggggacggtccgcaggcgcagatcctggtctccggcgtgaccatgcccgac
gcgctcaaggcccagcggatgctggccgaggactggggcgtgcgggccgcggtgtggtcg
gccacgtcgtggtccgagctgcgccgcgaagcggtcgaggtggaccgggacaacctgctg
cacccggccgatccgccgcgcgtgccgtacgtgacgcaggcgctgagcggcgttcccggc
ccggtcgtggcggcctcggactggatgcgggcggtgcccgacctgatccgtccgtgggtc
cccaccgagatggtcaccctcggcaccgacgggttcggtttctccgacacccgcccggcc
gcgcggcggcacttcctggtcgacgccgagtcgatcacggtggccacgctggcggcgctg
gccggccgcggcgaggtcgagcaggcgaaggtggtggaggcggcgcggaagtaccgcatc
aacgacgtgtcggcggccggaccgcagctgtccgactcgggcaacgcctga
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