KEGG   Amycolatopsis cynarae: ORV05_25820
Entry
ORV05_25820       CDS       T09969                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
acyn  Amycolatopsis cynarae
Pathway
acyn03030  DNA replication
acyn03410  Base excision repair
acyn03420  Nucleotide excision repair
acyn03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:acyn00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    ORV05_25820 (ligA)
   03410 Base excision repair
    ORV05_25820 (ligA)
   03420 Nucleotide excision repair
    ORV05_25820 (ligA)
   03430 Mismatch repair
    ORV05_25820 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:acyn03032]
    ORV05_25820 (ligA)
   03400 DNA repair and recombination proteins [BR:acyn03400]
    ORV05_25820 (ligA)
Enzymes [BR:acyn01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     ORV05_25820 (ligA)
DNA replication proteins [BR:acyn03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     ORV05_25820 (ligA)
DNA repair and recombination proteins [BR:acyn03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     ORV05_25820 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     ORV05_25820 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     ORV05_25820 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      ORV05_25820 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD HHH_5 Nlig-Ia PTCB-BRCT HHH BRCT_2 Auto_anti-p27 Zn_ribbon_3
Other DBs
NCBI-ProteinID: WAL69818
LinkDB
Position
complement(5403131..5405227)
AA seq 698 aa
MSDVPAEVRERHGALAEEIRGHQFRYYVLDAPTISDGQFDELMHRLERLEAEYPGLVTPD
SPTQNVGGTFSTEFAAHDHLERMLSLDNVFDTEEMLAWIDRVEREVGGSTQYLCELKIDG
LAVNLLYERGRLTRALTRGDGRTGEDVTLNVRTLEQVPDTLTGTDEYPVPELIEVRGEVF
FRVEDFLDLNAKLVEAGKSPFANPRNTAAGSLRQKDPRVTRSRRLRMICHGLGRRDGFEP
ERQSQSYEALAAWGLPVSAHTKVFDTAKEVLAHIGYWGEHRHDAEHEIDGVVIKVDQVAL
QRRLGTTSRAPRWAVAYKYPPEEANTKLLDIQVNVGRTGRVTPFAVMEPVKVAGSTVAMA
TLHNAEEVKRKGVLIGDRVVIRKAGDVIPEVLGPVVEVRTGEEREFVMPTRCPECGTPLA
AQKEGDVDIRCPNARSCPAQLRERLFHLAGRGAFDIEVLGYEAASALLESGVVADEGDIF
ALDEEKLRQVELFRTKSGELSANAGKLLANLETAKDRPLWKVLVALSIRHVGPTAAQALA
REFGSLEAIEAADETALADVDGVGPTIAAAVREWFTVDWHREVVAKWRRAGVRMAEERDE
SIPRILEGLSIVVTGSLTGFSRDEAKEAIMARGGKAAGSVSKKTAFVVVGDAPGSKYDKA
VQLKVPVLDENGFRVLLEKGPEAAAEVALPAEGEQTGE
NT seq 2097 nt   +upstreamnt  +downstreamnt
atgtccgacgttcccgccgaggtgcgggaacggcacggtgcgctggccgaagagatccgc
ggccaccagttccgctactacgtgctggacgcgcccaccatctccgacggccagttcgac
gagctcatgcaccggctcgaacggctcgaggccgagtacccaggcctggtcacccccgac
tcgccgacgcagaacgtgggcggcaccttctccaccgagttcgccgcccacgaccacctc
gagcgcatgctcagcctcgacaacgtgttcgacaccgaggagatgctggcctggatcgac
cgggtcgaacgcgaggtcggcggctcgacgcagtacctgtgcgagctcaagatcgacggc
ctcgccgtcaacctgctctacgagcgcggcaggctcacccgcgcgctgacccgcggcgac
gggcgcaccggcgaggacgtcacgctcaacgtgcgcaccctggagcaggtgccggacacg
ctcaccggcaccgacgagtatccggtgccggagctgatcgaagtgcgcggcgaggtgttc
ttccgggtcgaggacttcctcgacctcaacgcgaagctggtcgaggcgggcaagtcgccg
ttcgcgaacccccgcaacaccgccgccggttcgctgcgccagaaggatccccgcgtcacc
cgcagccgccgcctgcggatgatctgccacgggctgggcaggcgggacggcttcgagccc
gagcgccagtcgcagtcgtacgaggcgctcgccgcctggggcctgccggtgtccgcccac
accaaagtgttcgacaccgccaaggaggtgctggcccacatcgggtactggggcgagcac
cggcatgacgccgaacacgagatcgacggcgtggtgatcaaggtcgaccaggtcgccctg
cagcgccgcctcggcaccacctcacgcgccccgcgctgggccgtggcgtacaagtacccg
ccggaagaggccaacaccaagctgctcgacatccaggtcaacgtcggccgcaccgggcgg
gtcaccccgttcgcggtgatggagccggtgaaggtggccgggtccacggtcgcgatggcc
accctgcacaacgccgaggaggtcaagcgcaagggcgtcctgatcggcgaccgggtggtg
atccgcaaggcgggcgacgtcatccccgaggtgctcggcccggtggtcgaggtgcgcacc
ggcgaggagcgcgagttcgtgatgccgacgcggtgcccggagtgcggcaccccgctggcc
gcgcagaaggagggcgacgtcgacatccgttgccccaacgcccggtcctgcccggcccag
ttgcgggagcgcctgttccacctggcgggccgcggcgccttcgacatcgaggtgctcggc
tacgaggcggcgagtgcgctgctggagtcgggtgtggtggccgacgagggcgacatcttc
gccctggacgaggagaagttgcggcaggtcgagctgttccgcaccaagtcgggggagctt
tcggcgaacgcgggcaagctgctggccaacctggaaacggcgaaggaccggccactgtgg
aaggtgctggtggcgttgtccatccggcacgtcggaccgaccgcggcccaggcgctcgcc
cgcgaattcggttcgctggaagcgatcgaggcggccgacgagacggcgctggccgatgtg
gacggtgtcggcccgacgatcgcggcggccgtgcgcgagtggttcaccgtggactggcac
cgggaggtggtggccaaatggcggcgggccggggtgcggatggccgaggagcgcgacgaa
tccatcccgcgcatcctggaggggctgtccatcgtggtgaccggatcgctgaccggattc
tcccgggacgaggccaaggaggccatcatggcccgcggcggcaaggcggccggttcggtg
tcgaagaagacggccttcgtggtggtcggggacgcgcccgggtccaagtacgacaaggcc
gtgcagctgaaggtgccggtcctggacgaaaacggtttccgggtgctgctggaaaaggga
ccggaggcggcggcggaggtcgcactgcccgccgagggtgagcagaccggtgagtga

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