Arcobacter defluvii: ADFLV_0214
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Entry
ADFLV_0214 CDS
T06891
Symbol
metH
Name
(GenBank) cobalamin-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
adz
Arcobacter defluvii
Pathway
adz00270
Cysteine and methionine metabolism
adz00450
Selenocompound metabolism
adz00670
One carbon pool by folate
adz01100
Metabolic pathways
adz01110
Biosynthesis of secondary metabolites
adz01230
Biosynthesis of amino acids
adz04981
Folate transport and metabolism
Module
adz_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
adz00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
ADFLV_0214 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
ADFLV_0214 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
ADFLV_0214 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
ADFLV_0214 (metH)
04980 Cobalamin transport and metabolism
ADFLV_0214 (metH)
Enzymes [BR:
adz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
ADFLV_0214 (metH)
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
CdhD
Motif
Other DBs
NCBI-ProteinID:
QKF76281
UniProt:
A0AAE7E5V0
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All DBs
Position
191064..194540
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AA seq
1158 aa
AA seq
DB search
MKELIENLISKKVLIIDGAMGTQLQIADIKKEEWLFEDLDLEGCNELLNLTAPHILETIH
DNYAKAGADLICTNTFGSMPWVLDEYNIGHMSYELSKLGASLVKKSCEKYSTPEKPRFAV
ASIGPGTKLPSLGHIKYDEMYEGYKIMAKGLVDGGTDIFLLETCQDPLQIKAALHALNDV
APQIPIMVSVTIELSGTMLIGTDAMTIAAIMAPFNILSLGFNCGTGPVQVHKHIKTLSQV
CKFPISVHSNAGLPQNRGGKTYYPMQPEEFTAHQKEFLKINGVSFLGGCCGTTPEHIEAL
AIAVDGMVPLKPCGFLKASLASLFNTVPLKQEPAPLLIGERSNATGSKAFRELLKENDYE
GTLSVGQQQVRAGAHVIDVSVGFAGRDERFDMDEVVSLYSQKISLPLMPDSTQILALEAA
LKQIGGRCIINSVNLEDGEEKFDAVCKLAKKFGAALVCLVIDEIGMAKSVERKLEVAERI
YDLCVNRHGFDSADLVFDMLTFTIGSGDDEYRNAGIDTLEAIREFQIRHPEVGTTLGLSN
ISFGLAANARIYLNSIYLDHCVKAGLTSAIVNVKHILPLNKISDEDRKACDDLIFNNQEN
GDPLFKFIEHFSNVGAQEEQSDEEYQKLEPIEKVKKLLLDGDKDRLLPLVEELRHTVQPE
IIVNEWLIDGMKIIGELFGSGQMQLPFVLQSAETMKATVDALNPYLPKQEKASETTLILG
TVKGDVHDVGKNLVDIILSNNGFKVVNIGIKAGLDTFVEKLQEHNAHAIGMSGLLVKSTA
VMKENLEELQKMGIKVPVLLGGAALTKNFIDEYCRPYYDGPIFYCRDAFDGVVSMQRIEK
GDENNTALAADLIQIHDTSNRVEEEVVEIPPYEEIPMPQRGKFVFPPIWERITKTGKELD
KELIFKWINHRVLFRQRWGYKRGKQDSETFLKYEREVVEPTYEALKAELVDKDIFDPIAI
YAYYPCISHDNKLYIFDRKYLFNSLEESKNVPPLDEAIKVLEFPRQKRKPFRCIADFFAN
DRLDVVAFTLASAGLKISDYERSLYDKGEFSKYYQVHGLGVELAEALAEVLHKQIRLDLD
IVPKEGHTLNDVQMKQYVGCRYSPGYAACPDLAMNRDIFDLLNPEEFGIELSETFQMHPE
QTTCAIVVTNPEANYYNI
NT seq
3477 nt
NT seq
+upstream
nt +downstream
nt
atgaaagaattaatagaaaatttaattagtaaaaaggtactaattattgatggagctatg
ggaacacagcttcaaattgcagatataaaaaaggaagaatggctttttgaggatttagat
ttagaaggatgtaatgaacttttaaatttaactgctccacatattttggaaactattcat
gataattatgcaaaagctggtgctgatttaatttgtacaaatacttttggttctatgcct
tgggttttagatgaatataatatcggacatatgtcttatgaattatcaaaattaggtgca
agtttagtaaaaaaatcttgtgaaaaatatagcacacctgaaaaacctagatttgctgta
gcatcaattggacctggaacaaaacttccatcacttggtcatataaaatatgatgagatg
tatgaaggttataaaatcatggctaaaggtttagttgatggtggaactgatatcttttta
cttgaaacatgccaagatccacttcaaataaaagcagcacttcatgcactaaatgatgtg
gcaccacaaattccaataatggtttctgttacgattgagttaagtggaactatgcttatt
ggaacagatgcaatgacaattgctgctattatggcaccatttaatattttatctttagga
tttaactgtggaactggacctgttcaagttcataaacatattaaaacattaagccaagtt
tgtaagtttccaatatcagttcactcaaatgcaggacttcctcaaaatagaggtggaaaa
acttattatccaatgcaaccggaagagtttacagcacatcaaaaagagtttttaaaaata
aatggagtttcatttttaggtggttgttgtggtaccactcctgaacatattgaagctttg
gcaattgcagttgatggaatggtaccacttaaaccttgtggatttttaaaagcttcatta
gcaagtttatttaatacagttcctttaaaacaagaaccagcaccacttttaattggtgag
agaagtaatgcaactggaagtaaagcatttagagaactcttaaaagagaatgattatgaa
ggaacattaagtgttggtcaacagcaagtaagagctggtgctcatgtaattgacgtttct
gttgggtttgctggacgtgatgagagatttgatatggatgaggttgtatcactttattca
caaaaaatttcactaccactaatgcctgattcaactcaaatattggcacttgaagctgct
ttaaaacaaattggtggaagatgtatcatcaactcagtaaatcttgaagatggagaagaa
aagtttgatgctgtttgtaaattagctaaaaaatttggagcagcacttgtttgtctagta
attgatgaaattggaatggcgaaatcagtagaaagaaagcttgaagttgcagaaagaatc
tatgatttatgtgtaaatagacatggatttgactctgctgatttagtatttgatatgctt
acatttacaattggttcaggtgatgatgaatatagaaatgcaggtattgatactcttgaa
gcaattagagagttccaaatcagacatccagaagttggaactactttaggattatcaaat
atctcttttggtttagcagcaaatgctagaatttatctaaattctatctatcttgaccat
tgtgtaaaagctggattaacaagtgccattgtaaatgtaaaacatattttacctctaaat
aaaattagtgatgaagatagaaaagcttgtgatgatttaatttttaataatcaagagaat
ggtgacccactgtttaaatttatcgaacatttttcaaacgttggagcacaagaagaacaa
agtgatgaagagtatcaaaaactagaaccaattgagaaagttaaaaaactattacttgat
ggagataaagatagattattaccacttgttgaagagttaagacatacagttcaaccagaa
atcattgtaaacgagtggttgatagatggtatgaaaattattggagagttatttggtagt
gggcaaatgcagttaccatttgtacttcaaagtgctgaaactatgaaagcaactgtagat
gcacttaatccttatttaccaaaacaagaaaaagctagtgaaacaacattaattcttgga
actgtaaaaggtgatgttcatgatgttggtaaaaacttagttgatattattctttcaaat
aatggatttaaagttgtaaatattggtataaaagctggtttagatacttttgttgaaaag
cttcaagagcataatgctcatgctattggaatgagtggattacttgttaaatcaacagca
gttatgaaagagaatcttgaagagttacaaaaaatgggaattaaagttcctgttttactt
ggtggggcagcacttactaaaaactttattgatgagtattgtagaccttattatgatgga
ccaattttttattgtagagatgcttttgatggtgttgtttctatgcaaagaattgaaaaa
ggtgatgaaaataatactgcacttgctgctgatttaatccaaattcatgatacaagcaat
agagttgaagaagaagttgtagaaattccaccttatgaagagattccaatgccccaacgt
ggaaaatttgtatttcctccaatttgggagagaataacaaaaactggaaaagaactagat
aaagagttgatttttaaatggataaatcacagggttttatttagacaaagatggggatat
aaaagaggtaaacaagattctgaaactttcttaaaatatgaaagagaagttgttgagcca
acttatgaagctttaaaagctgaattagttgataaagatatttttgatccaattgctatt
tatgcttattatccttgtatttcacacgataataaactttatatttttgatagaaaatat
ctgtttaactctttagaagagtctaaaaatgtaccgccactagatgaagcaataaaagtt
ttagagtttccaagacaaaaaagaaaaccatttagatgtattgcagatttctttgcaaat
gatagacttgatgttgttgcctttacacttgctagtgctggacttaaaatctctgattat
gaaagaagtttatacgataaaggtgaatttagtaaatattatcaagttcatggtcttgga
gttgaacttgctgaagctttagctgaggttttacacaagcaaataagacttgatttggat
attgtgccaaaagagggacatactttaaatgacgttcaaatgaaacaatatgtaggttgt
agatattctccaggatatgcagcttgtccagatttagctatgaatagagatatttttgat
ttactaaatccagaagagtttggaatagaattatctgaaacattccaaatgcatccagaa
caaacaacttgtgcaatagttgtaacaaacccagaagctaactactataatatctag
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