Aeromonas encheleia: NCTC12917_00344
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Entry
NCTC12917_00344 CDS
T06531
Symbol
metH
Name
(GenBank) Homocysteine-N5-methyltetrahydrofolate transmethylase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
ael
Aeromonas encheleia
Pathway
ael00270
Cysteine and methionine metabolism
ael00450
Selenocompound metabolism
ael00670
One carbon pool by folate
ael01100
Metabolic pathways
ael01110
Biosynthesis of secondary metabolites
ael01230
Biosynthesis of amino acids
ael04980
Cobalamin transport and metabolism
ael04981
Folate transport and metabolism
Module
ael_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
ael00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
NCTC12917_00344 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
NCTC12917_00344 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
NCTC12917_00344 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
NCTC12917_00344 (metH)
04980 Cobalamin transport and metabolism
NCTC12917_00344 (metH)
Enzymes [BR:
ael01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
NCTC12917_00344 (metH)
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GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
CdhD
Motif
Other DBs
NCBI-ProteinID:
VEG94861
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Position
1:364737..368420
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AA seq
1227 aa
AA seq
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MSSIKSDIKKKLEACLRERILIIDGAMGTMIQGYKLGEADYRGARFADWHTDIKGNNDLL
VLTRPGVIREIHDQYCAAGADILETNTFNATRIAMADYEMEAFSAEINREAARLARAVAD
DWTAKEPHKPRFVAGVLGPTNRTASISPDVNDPGKRNVTYDQLVAAYTESTHALIEGGAD
LILIETIFDTLNAKAAAFAVEGVFEELGYALPVMISGTITDASGRTLSGQTTEAFYHSLR
HVKPLSFGLNCALGPDELRQYVEELSRISESHVSAHPNAGLPNAFGEYDLDAGEMAEHIR
EWAQSGFLNLVGGCCGTTPTHIRAMADAVAGIRPRALPELPVACRLSGLEPLIITAESMF
VNVGERTNVTGSAKFKRLIKEGLYDEALDVAKQQVESGAQIIDINMDEGMLDAEAAMVRF
LNLIAGEPDIARVPVMIDSSKWEVLEAGLKCVQGKPVVNSISMKEGEEKFIQQAKLLRRY
GAAVIVMAFDEVGQADTRARKFEICQRAYRILVDRVGFPPEDIIFDPNIFAVATGIDEHN
NYAVDFIEAVKDIKDNLPHAMISGGVSNVSFSFRGNEPVREAIHAVFLYHAIQNGMDMGI
VNAGQLAIYEDIPAELKEKVIAVVLNLNDNATEDLLAIAEKYRGAGAQAEDPRDQEWRSW
PVGKRLEHALVKGITDFIEEDTEEARAGAEKPLHVIEGPLMDGMNVVGDLFGAGKMFLPQ
VVKSARVMKRAVAYLQPYIEQEKEGGSSNGKIVMATVKGDVHDIGKNIVGVVLQCNNYEI
VDLGVMVSCEKILKTAREVNADMIGLSGLITPSLDEMVHVAKEMERQGFTLPLLIGGATT
SKAHTAVKIEQNYREPVVYVSNASRAVGVAQSLLNPELKPAFVARIDKEYEIAREQHARK
QPRSKPVSLAHARANRQQLDWVGYQPPAPREPGVQTFENVPISVLRPYIDWTPFFLSWEL
AGKYPRILEDEVVGEEATKLFADANAMLDQLERDGSVRCAGIIGLFPANGVGDSIEVYTD
ESRTEVRKVLHHLRQQSEKQGFPNYCLADYVAPKESGKPDWIGAFAVTGGIGEETIANAY
KAQHDDFNAILVQAVCDRLAEAFAEYLHEQVRKRHWGYAQDEALSNEELIRENYQGIRPA
PGYPACPEHTEKGSIWELLGVEQAIGMQLTESYAMWPGAAVSGWYFSHPDSKYFAVAQIQ
QDQVEDYAQRKGMSLVEAERWLGPNLS
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgagcataaagtcggacataaagaagaaactggaagcctgtctcagggagcggatc
ctgatcatcgacggtgccatgggcaccatgatccagggctacaagctgggtgaggcggac
tatcgcggtgcgcgttttgccgattggcataccgacatcaagggtaacaacgatctgctg
gtgctgacccgacccggggtgatccgcgagatccacgatcaatattgcgccgccggggcc
gacatcctcgagaccaacaccttcaacgctacccgtatcgccatggccgattacgagatg
gaggccttctccgccgagatcaaccgcgaggccgcccgtctcgcccgcgccgtcgccgac
gactggaccgccaaagagcctcacaagccgcgcttcgtggccggggtgctgggccccacc
aaccgcaccgcctccatctcgccggacgtcaacgatccgggcaagcgcaacgtcacctat
gaccagctggtggccgcctacacggaatcgacccatgccctgatcgagggcggcgccgac
ctcatattgatcgagaccatcttcgataccctcaacgccaaggccgccgccttcgcggtg
gaaggggtgttcgaggagctgggttatgcgctgccggtgatgatctccggcaccatcacc
gatgcctcgggtcgcaccctctccggccagaccacggaagccttctaccattccctgcgc
cacgtcaaaccgctgtcgttcggcctcaactgcgcgctcggcccggacgagctgcgccag
tatgtggaggagctgtcgcgcatcagcgagagccatgtcagcgcccaccccaacgccggt
ctgcccaacgccttcggcgagtacgatctggatgcgggggagatggccgagcatatccgc
gagtgggcccagagcggcttcctgaacctggtggggggctgctgcggcaccaccccgacc
cacatacgcgccatggcggacgccgtggcgggcatcagaccgcgcgccctgcccgagctg
ccggtggcctgccggctctccggcctcgagccgctgatcatcaccgcggagtccatgttc
gtgaacgtgggggagcgcaccaacgtcaccggctcggccaagttcaagcggctgatcaag
gagggactctacgacgaggccctggacgtggccaagcagcaggtcgagagcggcgcccag
atcatcgacatcaacatggacgaggggatgctggacgccgaggcggccatggtgcgcttc
ctcaacctgatcgccggcgagccggacatcgcccgggtgccggtgatgatcgactcctcc
aagtgggaggtgctggaggcgggcctcaagtgcgtgcagggcaagccggtggtcaactcc
atctccatgaaggagggggaggagaagttcatccagcaggccaaactgctgcgtcgctac
ggcgccgccgtcatcgtcatggcgttcgacgaggtgggccaggccgatacccgtgcccgc
aagttcgagatctgccagcgcgcctaccgcatcctggtggacagggtcggcttcccgccg
gaagacatcatcttcgatcccaacatcttcgcggtggcgaccggcatcgacgagcacaac
aactacgcggtggacttcatcgaggcggtgaaggacatcaaggacaacctgcctcacgcc
atgatctccggcggcgtctccaacgtctccttctccttccgtggcaacgagccggtgcgc
gaggccattcacgccgtcttcctctaccacgccatccagaacggcatggacatgggcata
gtcaacgccggtcagctcgccatctatgaagacatcccggcggagttgaaagagaaagtc
atcgccgtggtgctcaacctcaacgacaacgccaccgaggatctgctggccatcgccgag
aagtatcgcggcgccggtgcccaggccgaggatccgcgggatcaggagtggcgtagctgg
ccggtgggcaagcggctggagcatgccctggtcaagggcatcaccgacttcatcgaagag
gataccgaagaggcgcgggccggggccgagaagccgctgcacgtgatcgaggggccgctg
atggacggcatgaacgtggtcggcgatctgttcggcgcgggcaagatgttcctgccccag
gtggtgaagtcggcgcgggtgatgaagcgggcggtggcctacctgcagccctatatcgaa
caggagaaggaggggggctccagcaacggcaagatagtgatggccacggtgaagggagac
gtgcacgacatcggcaagaacatcgtcggcgtggtgttgcagtgcaacaactacgaaatc
gtcgatctcggggtcatggtctcctgcgagaagatcctcaagaccgccagggaagtgaat
gccgacatgatcggattgtccggcctgatcaccccttccctcgacgagatggtgcacgtg
gccaaggagatggagcgtcaggggtttacactgccgctgctgatcggtggtgctaccacc
tccaaggcgcacaccgcggtcaagatagagcagaactaccgtgaacccgtggtctatgtg
tcgaacgcatcgcgggcggtcggggtggctcagagcctgctcaaccccgagctcaagccc
gccttcgtggcccgcatcgacaaggagtacgagatagcccgggagcagcatgcccgcaag
caaccgaggtccaagccggtcagcctggcccatgcccgcgctaaccgccagcagttggac
tgggtcggctatcagccgccagccccccgcgagccgggtgtgcagaccttcgaaaacgtg
cccatctcggtgttgcgcccctacatcgactggacgcccttcttcctgagctgggagctg
gcgggcaagtatccgcgcatcctggaggacgaagtcgtcggtgaggaggcgaccaagctg
tttgccgatgccaacgccatgctggatcagctcgaacgggatggcagcgtgcgctgcgcc
ggtatcataggcctgttccccgccaacggcgtcggcgacagcatcgaggtctataccgac
gaatcgcgcaccgaggtgcgcaaggtgttgcaccacctgcgccaacagagcgagaagcag
ggcttccccaactactgcctggcggactatgtggcgccgaaagagagcggcaagccggac
tggatcggcgccttcgccgtgaccggcggcatcggcgaagagaccatcgccaacgcctac
aaggcccagcatgatgatttcaatgccattctggtgcaggcggtgtgcgaccgcctggcg
gaagccttcgccgagtacctgcacgagcaggtgcgcaagcggcactggggttatgcccaa
gatgaggccctcagcaacgaggagctcattcgcgagaactatcagggcatacgcccggcc
cccggttacccggcctgcccggagcataccgagaagggcagcatctgggagctgctgggc
gtcgagcaggccatcggcatgcagctgaccgaatcctacgccatgtggccgggggcggcg
gtgtccggctggtacttctcccaccccgacagcaagtactttgcggtggcgcagatccag
caggatcaggtcgaagactacgcccagcgcaagggcatgagcctggtcgaggccgagcgc
tggctggggccaaacctgagttga
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