Aeromicrobium erythreum: AERYTH_06540
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Entry
AERYTH_06540 CDS
T04236
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
aer
Aeromicrobium erythreum
Pathway
aer00020
Citrate cycle (TCA cycle)
aer00630
Glyoxylate and dicarboxylate metabolism
aer00785
Lipoic acid metabolism
aer01100
Metabolic pathways
aer01110
Biosynthesis of secondary metabolites
aer01120
Microbial metabolism in diverse environments
aer01200
Carbon metabolism
aer01210
2-Oxocarboxylic acid metabolism
Module
aer_M00009
Citrate cycle (TCA cycle, Krebs cycle)
aer_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
aer00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
AERYTH_06540 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
AERYTH_06540 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AERYTH_06540 (kgd)
Enzymes [BR:
aer01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
AERYTH_06540 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
AERYTH_06540 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
AERYTH_06540 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
AERYTH_06540 (kgd)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
PAD
Motif
Other DBs
NCBI-ProteinID:
ALX04369
UniProt:
A0A0U4BGF1
LinkDB
All DBs
Position
complement(1386874..1390701)
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AA seq
1275 aa
AA seq
DB search
MAESSHDPSTPDFGTNQWLVEEMYDQYKADPASLDPTWVTFFEEGDGAALLRDNGTAPSS
NGAARNGTSANGTSANGSGPAAATVAEKKPEPAPAKTPEKKPEPAAAAPAPKKAEPAAAK
PAESKAPEKKPQAARPAGRSTDPKSTSAAPEPSGPGEVERVPLKGAPARTAANMDASLEV
PTATSVRSVPVKLLFDNRIVINNHLARARGGKVSFTHLIGYAVVKALTAMPEMNTGYDTD
EKGKPVQLKPEHVNFGLAIDTKNAKGERQLLVPSIKAAETMNFAQFWQAYEAMVKKARDG
KLEVSDFQGTTASLTNPGGIGTNHSVPRLMKGQGVIVGVGSMEYPPEFQGASEHTIAHLA
VSKMMTLTSTYDHRVIQGAQSGEFLRRIHQLLLGEEGFYDEIFQALRIPYEPIRWAQDIA
VSHDDEVHRQARVLELIHAFRVRGHLMADTNPLEYRQRSHPDLDTASHGLTLWDLDREFA
TGSFASGTGKRFMKLREILGVLRDSYCRSIGLEYMHIQDPGERQWLQDRIEVGHTKPPRE
EQLRILLKLNQAEAFETFLQTKFVGQKRFSLEGGETTIPLLDEICEEAAADGLEEVCIGM
AHRGRLNVLVNIAGKSAGTVFREFEGNIDPRTVQGSGDVKYHLGVEGEFRSEHGDTIKVS
VAANPSHLEVVDPVLEGITRAKQDRLNRGAEFPVLPVLVHGDAAFAGQGVVAETLNLSQL
RGYRTGGTIHVIVNNQVGFTTSPSSSRSSTYCTDVARMVQAPILHVNGDDPEACIRVADL
AYEYRKTFNKDVVIDLVCYRRRGHNEGDDPSFTQPLMYDTINAKKSVRKLYTEALVGRGD
ITIEEAEAALADYQSQLERNFADVKEATSSDADYTRTPDYPEKPEQEGALETAVSPEVMK
AVSSAYTSVPDGFTVHPKVLPQLQRRAQSIETGPIDWGTGEIIAFGSLLLEGRPVRLAGQ
DSRRGTFSSRFATIIDRNNGSEWTPLSHVGDEQATFYIYDSLLSEYAALGFEYGYSVARP
EALTLWEAQFGDFVNGAQPVIDEYISSGETKWGQKSGVVLLLPHGYEGQGPDHSSARIER
FLQLAANDEMTIAQPSTSASYFHLLRRHTLEGQHRPLIVFTPKQLLRRKSAASQPDEFTS
GQWRPVIGDDSVDAEKVDTVLLCSGRIAHDLFDERAKREGDDPTTAIVRLEQLYPRPVEQ
IKTELARFSGVKNVRWVQDEPANQGPWPDAALHYPDAVASGALTLVSRPASSTTAVGSKS
RHDAEQRELMDAAFA
NT seq
3828 nt
NT seq
+upstream
nt +downstream
nt
gtggccgagtcctcacatgacccgtcaacccccgacttcgggacgaaccagtggctcgtc
gaggagatgtacgaccagtacaaggcggaccccgcctccctcgacccgacctgggtgacg
ttcttcgaggagggtgacggcgcggcgctcctgcgggacaacggcaccgccccctcctcg
aacggggccgcgcgcaacggcacctcggcgaacggcacgtccgcgaacggctctgggccg
gcagccgccacggtcgccgagaagaagcccgagcccgcccccgcgaagaccccggagaag
aagcccgagcctgccgctgcagcacccgcgccgaagaaggccgagcccgccgccgcgaag
cctgcggagagcaaggcgccggagaagaagccgcaggctgcacgtcccgcaggccgctcc
accgacccgaagtcgacgtcggccgcgcccgagccctcgggtccgggcgaggtcgagcgc
gtgccgctcaagggcgcgccggcgcgcaccgcggccaacatggacgccagcctcgaggtc
cccaccgccacgagcgtgcgctcggtgccggtcaagctgctcttcgacaaccgcatcgtc
atcaacaaccacctcgcccgcgcccgcggcggcaaggtgtcgttcacccacctcatcggc
tacgccgtcgtcaaggccctcacggccatgccggagatgaacaccggctacgacaccgac
gagaagggcaagccggtccagctgaagcctgagcacgtcaacttcggcctcgcgatcgat
acgaagaacgccaagggcgagcgccagctcctcgtgccgtccatcaaggccgccgagacc
atgaacttcgcgcagttctggcaggcgtacgaggcgatggtcaagaaggcccgcgacggc
aagctcgaggtctccgacttccagggcaccaccgccagcctcaccaaccccggaggcatc
ggcaccaaccactccgtcccgcggctcatgaagggtcagggcgtcatcgtcggcgtcggc
tccatggagtacccgccggagttccagggcgcgtccgagcacaccatcgcccacctcgct
gtcagcaagatgatgacgctgacctcgacctacgaccaccgcgtcatccagggtgcgcag
tcgggcgagttcctgcgtcggatccaccagctgctcctcggcgaggagggcttctacgac
gagatcttccaggcgctgcggatcccctacgagccgatccgctgggcccaggacatcgcc
gtcagccacgacgacgaggtgcaccgccaggcgcgcgtgctcgagctgatccacgccttc
cgcgtgcgcggtcacctcatggccgacacgaacccgctcgagtaccgccagcgcagccac
cccgacctcgacaccgcgtcgcacggcctgaccctgtgggacctcgaccgcgagttcgcc
accggctcgttcgcgagcggcacgggcaagcgcttcatgaagctgcgcgagatcctcggc
gtcctgcgcgactcctactgccgctccatcggcctggagtacatgcacatccaggacccg
ggcgagcgtcagtggctgcaggaccgcatcgaggtgggccacacgaagcccccgcgcgag
gagcagctgcgcatcctgctgaagctcaaccaggccgaagcgttcgagaccttcctgcag
acgaagttcgtcggccagaagcggttcagcctcgagggcggggagaccaccatcccgctg
ctcgacgagatctgcgaggaggctgccgccgacggcctcgaggaggtctgcatcggcatg
gcccaccgcggccgtctcaacgtcctcgtcaacatcgccggcaagagcgccggcacggtg
ttccgcgagttcgagggcaacatcgacccccgcacggtgcagggctccggcgacgtcaag
taccacctgggcgtcgagggcgagttccgctccgagcacggcgacacgatcaaggtgtcg
gtggccgccaacccgtcgcacctcgaggtcgtcgacccggtgctcgagggcatcacccgc
gcgaagcaggaccgtctcaaccgcggtgccgagttcccggtgctgccggtcctcgtgcac
ggcgacgccgcgttcgccggccagggtgtcgtcgcggagacgctgaacctctcgcagctg
cgcggctaccgcacgggcggcacgatccacgtgatcgtcaacaaccaggtcggcttcacg
acgagcccgtcgtcgtcgcgctcctcgacctactgcaccgacgtcgcccgcatggtccag
gcgccgatcctgcacgtgaacggcgacgacccggaggcgtgcatccgcgtcgccgacctc
gcctacgagtaccgcaagacgttcaacaaggacgtcgtgatcgacctggtctgctatcgc
cgccgcggccacaacgagggcgacgacccgtcgttcacgcagccgctgatgtacgacacg
atcaacgcgaagaagtcggtgcgcaagctctacaccgaggcgctcgtgggtcgtggcgac
atcaccatcgaggaggccgaggccgccctcgcggactaccagtcccagctcgagcgcaac
ttcgccgacgtcaaggaggccacctcctccgacgccgactacacgcgcacccccgactac
cccgagaagcccgagcaggagggcgcgctcgagacggctgtgtcccccgaggtcatgaag
gccgtgtcgtcggcctacacgtccgtgcccgacggcttcacggtccacccgaaggtgctc
ccccagctgcagcgtcgcgcccagtccatcgagacgggcccgatcgactggggcacgggc
gagatcatcgcgttcgggtcgctgctgctcgagggtcgccctgtgcgcctcgccggccag
gactcgcggcgcggcacgttctcctcgcgcttcgcgacgatcatcgaccgcaacaacggc
agcgagtggaccccgctgtcgcacgtcggcgacgagcaggcgacgttctacatctacgac
tcgctgctgagcgagtacgccgcgctcggcttcgagtacggctactccgtggcgcgtccg
gaggccctcaccctgtgggaggcgcagttcggcgacttcgtcaacggcgcccagccggtc
atcgacgagtacatctcctccggtgagacgaagtggggccagaagtccggcgtcgtgctg
ctcctgccccacggctacgagggccaggggccggaccactcgtcggcgcgcatcgagcgg
ttcctgcagctcgccgccaacgacgagatgacgatcgcccagccgtcgacgtcggcgtcg
tacttccacctgctgcgtcggcacacgctggagggccagcaccgtccgctcatcgtgttc
acgcccaagcagctgctgcgtcgcaagagcgcggcgtcgcagccggacgagttcacgtcg
ggccagtggcgtccggtcatcggcgacgactccgtcgacgccgagaaggtcgacacggtg
ctgctgtgctcgggccggatcgcgcacgacctgttcgacgagcgcgctaagcgtgagggc
gacgacccgacgacggcgatcgtccgcctcgagcagctgtacccgcgcccggtcgagcag
atcaagaccgagctcgctcgcttcagcggcgtgaagaacgtccgctgggtgcaggacgag
cccgcgaaccagggtccgtggcccgacgccgcactgcactaccccgacgccgtggcgtcc
ggtgcgctgacgctcgtgtcgcgcccggcgtcgtcgacgacggccgtgggctcgaagtcg
cggcacgacgccgagcagcgtgagctgatggacgcggcgttcgcctga
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