KEGG   Actinobacillus equuli subsp. equuli: ACEE_02805
Entry
ACEE_02805        CDS       T03501                                 
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase
  KO
K00163  pyruvate dehydrogenase E1 component [EC:1.2.4.1]
Organism
aeu  Actinobacillus equuli subsp. equuli
Pathway
aeu00010  Glycolysis / Gluconeogenesis
aeu00020  Citrate cycle (TCA cycle)
aeu00620  Pyruvate metabolism
aeu00785  Lipoic acid metabolism
aeu01100  Metabolic pathways
aeu01110  Biosynthesis of secondary metabolites
aeu01120  Microbial metabolism in diverse environments
aeu01200  Carbon metabolism
aeu01210  2-Oxocarboxylic acid metabolism
Module
aeu_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:aeu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    ACEE_02805 (aceE)
   00020 Citrate cycle (TCA cycle)
    ACEE_02805 (aceE)
   00620 Pyruvate metabolism
    ACEE_02805 (aceE)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    ACEE_02805 (aceE)
Enzymes [BR:aeu01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     ACEE_02805 (aceE)
SSDB
Motif
Pfam: PDH_E1_M Transketolase_C_1 Transketolase_N Transketolase_C
Other DBs
NCBI-ProteinID: AIZ78726
LinkDB
Position
615150..617804
AA seq 884 aa
MSELERDVDPFETKEWLESLDSLIRVEGVERAQFIIDELLSQARKDGVPVQSGVTTAYVN
TIPVSAQPAYPGDHKIERRIRSAVRWNAIAMVLRSQKKDLDLGGHISTFQSAATMYEVCY
NHFFKAATEKNGGDLVFFQGHAAPGMYARAYVEGRLTEEQLDNFRQEAFADGLSSYPHPK
LMPEFWQFSTVSMGLGPVNAIYQARFLKYLENRGLKDTSDQKVYAFLGDGEMDEIESKGA
LTFAAREKLNNLIFTVSCNLQRLDGPVNGNGKIVQELEGLFTGAGWEVIKVLWGSNWDKL
FAKDTSGKLAQLMMEVVDGDYLTFKSKDGAYIREHFFGRYPETAALVADMTDEEIWDLRR
GAHDSEKLYAAYAKAQKSDKPVVILAHQVKGYKIPEAESKNTAHQSKKMSLESLKGFRDY
FELPLTDEQVENLEYIKFAEGSEEYNYIHGQRKALNGYVPARRPKFDVEYKVPALEEFKA
LLEEQPRGISTTMAFTRALNILLKDKNIGKTIVPMIVDEARTFGMEGLFRQVGIYNPHGQ
NYTPSDRDLVAYYREAKDGQVLQEGINELGGAASWVAAATSYSVSNQPMIPFFIYYSMFG
FQRVGDMMWLAGDQLARGFMVGGTSGRTTLNGEGLQHEDGHSHIQAGIIPNCITYDPSFA
FEVAVIMQDGINRMYGEKQEDVFYYMTTLNEVMDQPAMPEGAEEGIRKGLYKFETVKGKG
KGHVQLLGSGAIMRHVREAAQILANDYGVTSDVFSAPSFNELAREGNDAVRWNLLHPTAE
QRVPYVAQVLADLPTVASTDYVKQYADQIRAFVPSKHFHVLGTDGFGRSDSRANLREHFE
VDARYVVVAALSQLAKEGTVETKVVADAIAKFGLNVDRINPLYA
NT seq 2655 nt   +upstreamnt  +downstreamnt
atgtcagagttagaaagagatgtagatccatttgaaaccaaagagtggttagaatcactt
gattcattaatccgtgtagaaggtgttgaacgtgcacaattcattatcgatgaattatta
agccaagcgcgtaaagatggcgtgccggttcaatctggtgtgacaacagcgtatgtaaat
actatccctgtgtctgcacaaccagcttacccgggtgaccacaaaattgaacgtcgtatt
cgttctgcagtacgttggaacgctatcgcaatggttttacgtagccagaagaaagatctt
gacttaggtggtcatatttcaacattccaatcagcggcaacaatgtatgaagtgtgctac
aaccacttcttcaaagcggcaactgagaaaaatggtggcgacttagtattcttccaaggt
cacgcagcaccaggtatgtatgcgcgtgcttatgttgaaggtcgtttaacggaagaacaa
ttagacaatttccgtcaagaagcatttgcggatggtttatcttcatacccgcacccgaaa
ttaatgcctgaattctggcaattctcaaccgtatcaatgggtttaggtcctgttaatgcg
atttatcaagcacgtttcctaaaatatcttgaaaaccgtggcttaaaagatacgtcagac
caaaaagtttacgcattcttaggcgatggtgagatggatgaaatcgagtctaaaggtgcg
ttaacatttgctgctcgtgaaaaattaaataacttaattttcactgtaagctgtaactta
caacgtttagacggtccggtaaacggtaacggtaaaatcgttcaagaattagaaggttta
ttcaccggtgcaggttgggaagtaatcaaagtattatggggcagcaactgggataaatta
ttcgcgaaagatacttcaggtaaattagcacaattaatgatggaagtggttgatggtgac
tacttaaccttcaaatcaaaagatggcgcttatattcgtgaacacttcttcggtcgttac
ccagaaacagctgcattagtagcggatatgacagacgaagagatttgggatcttcgccgt
ggtgcgcacgacagcgaaaaactttacgctgcatatgcgaaagcacaaaaatcagataaa
ccagttgtgattttagctcaccaagttaaaggttataaaatccctgaagcagaaagtaaa
aatactgctcaccaatcgaaaaaaatgtcattagaaagcttaaaaggcttccgtgactac
ttcgaattaccgttaaccgatgagcaagtagaaaatcttgagtacatcaaatttgctgaa
ggttctgaagaatacaactatattcacggtcaacgtaaagcattaaacggttatgttccg
gctcgtcgtcctaaatttgacgtagagtacaaagtacctgcattagaagaattcaaagcg
ttacttgaagaacaaccacgtggtatttcaaccacaatggcgtttacgcgtgcattaaat
atcttattaaaagataaaaatatcggtaaaacaatcgttccgatgatcgtagacgaagcg
cgtacattcggtatggaaggtttattccgtcaagtgggtatttacaacccgcacggtcaa
aactatacgccttcagaccgcgatttagttgcttactaccgtgaagcgaaagacggtcaa
gtattgcaagaaggtattaacgaattaggtggtgcagcgtcttgggttgcagcggcaacg
tcttactctgtaagcaaccaaccgatgattccattcttcatctattactcaatgttcggt
ttccaacgtgtgggtgatatgatgtggttagcgggtgaccaattagctcgtggtttcatg
gtgggtggtacgtctggtcgtacaacattaaacggtgaaggtttacaacacgaagacggt
catagccatattcaagcgggtattatccctaactgtattacttacgacccatcatttgcg
tttgaagttgcggtaatcatgcaagacggtatcaaccgtatgtatggtgaaaaacaagaa
gatgttttctattacatgacaacattaaacgaagtaatggatcaacctgcaatgccggaa
ggtgctgaagaaggtatccgtaaaggtttatataaattcgaaaccgttaaaggtaaaggc
aaaggtcacgttcagttattaggttctggtgcaattatgcgtcacgttcgtgaagcggca
cagatccttgcgaatgactacggcgtaacttcagacgtattctctgcgccatcattcaat
gaattagcacgtgaaggtaacgatgcagtacgttggaacttattacacccaacagcggaa
caacgtgttccttatgtagcgcaagtgttagcggacttaccgacagttgcttcaactgac
tatgtgaaacaatatgcggatcaaatccgtgcgttcgtaccaagcaaacacttccacgta
ttaggtacagacggtttcggtcgttcagacagccgtgctaacttacgtgaacatttcgaa
gtagatgcacgttatgttgttgttgcagcgttatcacaattagcgaaagaaggcacagtg
gaaactaaagttgttgctgatgcaatcgctaaattcggcttaaacgtagatcgtattaac
ccgttatacgcataa

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