Actinopolyspora erythraea: CDG81_04580
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Entry
CDG81_04580 CDS
T05020
Name
(GenBank) 2-oxoglutarate dehydrogenase E1 component
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
aey
Actinopolyspora erythraea
Pathway
aey00020
Citrate cycle (TCA cycle)
aey00630
Glyoxylate and dicarboxylate metabolism
aey00785
Lipoic acid metabolism
aey01100
Metabolic pathways
aey01110
Biosynthesis of secondary metabolites
aey01120
Microbial metabolism in diverse environments
aey01200
Carbon metabolism
aey01210
2-Oxocarboxylic acid metabolism
Module
aey_M00009
Citrate cycle (TCA cycle, Krebs cycle)
aey_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
aey00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
CDG81_04580
00630 Glyoxylate and dicarboxylate metabolism
CDG81_04580
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CDG81_04580
Enzymes [BR:
aey01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
CDG81_04580
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
CDG81_04580
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
CDG81_04580
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
CDG81_04580
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
ASU77707
UniProt:
A0A099D2E8
LinkDB
All DBs
Position
complement(1012780..1016580)
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AA seq
1266 aa
AA seq
DB search
MSSSSPASQFGPNEWLIEEMYEQYLEDPSSVDSAWHEFFADYRPAGHSATESATAATGAT
TGQTTATATKSGERNGQVHDGARTTNTAPPASDAQQTGTRQGADGARQRDTSGAAGTQQD
ASGRSAASQQSAKPSPQEAAKAAPVKEEPSGEETKPLRGPAAAIAKNMEQSLSVPTATSV
RAVPAKLLFDNRIVINNHLKRNKGGKISFTHLIGYALVRALRDFPGMNRHYGEDAKGKPA
VVTPEHVNLGLAIDLPGKDGSRNLVVASIKACENMNFYQFWQAYEDIIRKARNNALTAED
FAGTTISLTNPGPSGTNHSVPRLTQGQSAIIGVGAMEYPAEFQGASEKALTEMGVSKIVT
LTSTYDHRVIQGAESGEFLRKVHQLLLGEDNFFDDIFSSLRIPYEPVRWSTDIPEGAVDK
TARVLELIDAYRTRGHLMADIDPLNYRQRRHEDLDVLSHSLTLWDLDREFPVGGFAGQEH
MTLRDVLGVLRDSYCRTVGVEYMHILEPDEREWLQHRVEKPHEKPDQSEQKYILSKLNAA
EAFETFLQTKYVGQKRFSLEGAETVVPLLDAVLDSSATSELDEVVIGMPHRGRLNVLANI
VGKPIAQIFQEFEGNLDPGQAHGSGDVKYHLGAEGKYFRMFGDGETKVSLTSNPSHLEAV
DPVLEGIVRAKQDILDKGQEGFTVLPVLLHGDAAFAGQGVVAETLNLSQLRGYRTGGTVH
VIINNQVGYTTTPESGRSSKYSTDVAKMTGSPVFHVNGDDPEACVWVAKLAVEYRNTFGK
DVVIDMVCYRRRGHNEGDDPSMTQPEMYDAIDKMRSVRKTYTESLIGRGDITVDEAEKAL
KDYANQLEHVFNEVRELENHPPEPSPSVESEQQIPAKLETGISEEELRRIADAQVDLPEG
FTPHSRVKPVLERRAKMGREGGIDWAFGELLALGSLATSGYPVRLTGQDTRRGTFGQRHA
VVIDRKTGAEYSPLQNLSPEQAKFLTYDSALSEFAAVGFEYGYSVAHQDAMVLWEAQFGD
FFNGAQSIIDEFISSGEAKWGQRSDVVMLLPHGHEGQGPDHSSARIERWLQLCAEGSMTV
AMPSTPANYFHLLRRHAMDGIDRPLVVFTPKSMLRLKEATSPIEHFTNGKFASVLDDPTE
PDPSQVRKLVLCTGKLYYELAAEQAKREAKDTAVARLEQLYPLPHRKLGRLFERYPNVEE
IRWTQEEPRNQGAWPFLGLALPREFGPEFASKLKVVGRRPMAAPATGLKKVHDVEQAEVI
NNAFAD
NT seq
3801 nt
NT seq
+upstream
nt +downstream
nt
gtgtccagcagcagccctgcgtcacagttcggccccaacgagtggttgatcgaggaaatg
tacgagcagtacctcgaagacccctcctcggtagactccgcctggcacgagttcttcgcg
gactaccgtccggcggggcactcggccaccgagtccgccactgcggcgacaggcgcaaca
acaggccagacgaccgcgaccgccaccaagtcgggtgagcgcaatggtcaggtgcacgac
ggtgcccgcacgaccaacacggcgccaccggcgagtgacgcgcagcagaccggcacccgg
cagggtgcggacggcgcccggcagcgcgacacctccggagcggcgggaacgcagcaggac
gcgagcggccggtcggccgcgtcgcagcagtccgccaagccctccccgcaggaggccgcc
aaggccgctccggtcaaggaggagccgagcggcgaggagaccaagccactgcgaggtccc
gccgcggcgatcgccaagaacatggagcagtcgctgtcggtgccgacggcgaccagcgtg
cgcgcggtgccggccaaactgctgttcgacaaccgcatcgtgatcaacaatcacctgaag
cggaacaagggcggcaagatctcgttcacccacctgatcgggtacgcactcgttcgggcg
ctgcgcgacttccccggcatgaaccgccactacggtgaggacgccaagggcaagcccgcc
gtggtgacgccggagcacgtcaacctcgggctggccatcgacctgcccggcaaggacggt
tcgcgcaacctggtggtggcctccatcaaggcctgcgagaacatgaacttctaccagttc
tggcaggcctacgaggacatcatccgcaaggcgcgcaacaacgcgctgaccgccgaggac
ttcgccggcaccacgatctcgctgaccaaccccggccccagcgggacgaaccactcggtg
ccccggctcacccagggccagagcgccatcatcggcgtcggtgccatggagtaccccgcc
gagttccagggcgccagcgagaaggccctgaccgagatgggcgtcagcaagatcgtcacg
ctgacctccacctacgaccaccgggtcatccagggcgcggagtccggcgagttcctgcgc
aaggtgcaccagctgctgctgggcgaggacaacttcttcgacgacatcttctcctcgctg
cgcatcccctacgagccggtccgctggtccaccgacatcccggagggcgccgtcgacaag
acggcccgggtgctggagctcatcgacgcctaccgcacccgcggccacctgatggccgac
atcgacccgctgaactaccggcagcggcggcacgaggacctcgacgtcctctcgcacagc
ctcacgctgtgggacctggaccgggagttcccggtcggcgggttcgcgggccaggagcac
atgacgctgcgcgacgtgctcggggtgctgcgggactcctactgccgcacggtcggcgtg
gagtacatgcacatcctcgagccggacgagcgcgagtggctgcagcaccgggtcgagaaa
ccgcacgagaagccggaccagtccgagcagaagtacatcctgtccaagctcaacgccgcc
gaggcgttcgagaccttcctgcagaccaagtacgtcggtcagaagcggttctccctggag
ggcgccgagaccgtggtcccgctgctggacgcggtgctggactcctcggcgacctccgag
ctggacgaggtcgtcatcggcatgccccaccggggcaggctcaacgtgctggccaacatc
gtcggcaaaccgatcgcgcagatcttccaggagttcgagggcaacctcgacccgggccag
gcgcacggctccggcgacgtgaagtaccatctcggcgccgagggcaagtacttccgcatg
ttcggcgacggcgagaccaaggtgtcgctgacctccaacccctcccacctggaggcggtg
gacccggtgctggagggcatcgtccgggccaaacaggacatcctggacaagggccaggag
ggcttcaccgtgctgccggtgctgctgcacggcgacgccgcgttcgccggacagggcgtg
gtcgccgagacgctgaacctctcgcagctgcgcggctaccgcaccggcggaaccgtgcac
gtgatcatcaacaaccaggtcggctacaccaccaccccggagtcgggccggtccagcaag
tactccaccgacgtggcaaagatgaccggctcgccggtgttccacgtcaacggcgacgac
cccgaggcctgcgtctgggtcgccaagctggccgtggagtaccgcaacaccttcggcaag
gacgtcgtcatcgacatggtgtgctaccgccgccgcgggcacaacgagggcgacgacccg
tcgatgacgcagccggagatgtacgacgcgatcgacaagatgcgcagcgtccgcaagacc
tacaccgagtcgctgatcggacgcggcgacatcaccgtcgacgaggccgagaaggcgctc
aaggactacgccaaccagctggagcacgtgttcaacgaggtgcgcgagctggagaaccac
ccgcccgagccgagcccctcggtggagtcggagcagcagatccccgccaagctggagacc
ggcatctccgaggaggagctccgccggatcgccgacgcgcaggtcgacctgccggagggc
ttcaccccgcactcccgcgtgaaaccggtgctggaacggcgcgccaagatgggccgggaa
ggcggcatcgactgggcgttcggcgagctgctcgcgctgggctcgctggccacctcgggc
tacccggtgcgactgaccgggcaggacaccaggcgcggcacgttcggccagcggcacgcg
gtggtcatcgaccgcaagaccggtgcggagtactccccgctgcagaacctctcgcccgag
caggccaagttcctgacctacgactcggcgctgtccgagttcgccgcggtcggcttcgag
tacggctactcggtggcccaccaggacgcgatggtgctgtgggaggcgcagttcggcgac
ttcttcaacggtgcccagtcgatcatcgacgagttcatctcctccggtgaggccaagtgg
ggccagcgctccgacgtggtcatgctgctgccgcacggccacgaggggcagggcccggac
cacagctcggcccgcatcgagcggtggctgcagctgtgcgccgaggggtcgatgacggtg
gccatgccctccacgcccgcgaactacttccacctgctgcgcaggcacgcgatggacggc
atcgaccggccgctggtggtgttcacccccaagtcgatgctgcggctcaaggaagccacc
agcccgatcgagcacttcaccaacggcaagttcgcctcggtgctcgacgacccgaccgag
ccggacccgtcccaggtccgcaaactcgtgctgtgcaccggcaagctgtactacgagctg
gccgccgagcaggccaagcgggaagcgaaggacaccgccgtggcccggctggagcagctc
tacccgctgccgcaccgcaagctgggcaggctgttcgagcgctaccccaacgtcgaggag
atccgctggacccaggaggagccgcgcaaccagggtgcgtggccgttcctcggcctcgcg
ctgccgcgcgagttcggtcccgagttcgccagcaagctcaaggtggtcgggcgccgtccg
atggccgctccggccaccgggctgaagaaggtgcacgacgtggagcaggcagaggtgatc
aacaacgccttcgccgactga
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