Actinopolyspora erythraea: CDG81_06475
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Entry
CDG81_06475 CDS
T05020
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
aey
Actinopolyspora erythraea
Pathway
aey00010
Glycolysis / Gluconeogenesis
aey00020
Citrate cycle (TCA cycle)
aey00620
Pyruvate metabolism
aey00785
Lipoic acid metabolism
aey01100
Metabolic pathways
aey01110
Biosynthesis of secondary metabolites
aey01120
Microbial metabolism in diverse environments
aey01200
Carbon metabolism
aey01210
2-Oxocarboxylic acid metabolism
Module
aey_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
aey00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
CDG81_06475 (aceE)
00020 Citrate cycle (TCA cycle)
CDG81_06475 (aceE)
00620 Pyruvate metabolism
CDG81_06475 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CDG81_06475 (aceE)
Enzymes [BR:
aey01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
CDG81_06475 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ASU78013
UniProt:
A0A223RQ69
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All DBs
Position
complement(1423637..1426477)
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AA seq
946 aa
AA seq
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MRQPDWRSSGEHAHDVFEEIPLTPHNNETGGANSPQRVRVIRNGLAAHLPDIAPDETEEW
LESFNSVLSVAGKQRARYLMLRLLQRAGETGVGIPSLTSTDYVNTIPTELEPWFPGDEET
ERRYRAWMRWNAAMMVHRAQRPGIGVGGHISSFASSASLYEVGFNWFFRGKDDPGGGDHL
YIQGHASPGIYARAFLEGRLSADQLDGFRQEYSHAGPGGGLPSYPHPRLMPGFWEFPTVS
MGLSPMNAIFQARFNRYLRDRGIKDTSDQHVWAFLGDGEMNEPESRGMLQVAANEGLDNL
TFVVNCNLQQLDGPVRGNGKIIQELEAFFRGAGWNVIKVIWGREWDSLLHADRDGALINL
MNSTPDGDYQTYKANDGAFVREHFFGRDPRTKEMVKNFTDDQIWGLRRGGHDYRKLYAAY
KAAMEHHGQPTVILAKTIKGYGLGAHFEGRNATHQMKKLALDDLKLFRDSLRIPISDAQL
EQDPYLPPYYHPGEDAPEIQYLRQRRSRLGGYLPERRTPAKPLVLPGDKVYDVVRQGSGK
QEVATTMAFVRLLKDLAKDPEIGPRLVPIIPDEARTFGMDSMFPSQKIYNPSGQTYTPVD
YQLMLAYRESDQGQILHEGINEAGSVASFTAAGTSYATHGEPMIPVYIFYSMFGFQRTGD
GLWAAGDQMARGFLLGATAGRTTLVGEGLQHADGHSQLLAATNPGVVSYDPAWAFEIAHI
VRDGLRRMYGEQPENVFYYLTVYNEPYQQPAEPEGIDVDGLLRGLYRYKRADGEQGPRAQ
LLTSGVAMPEVLRAQRLLGTEWGVSADVWSATSWTELRREAEAVDRDNLLHPDAERREPY
VTRVLRPESGPVVAVSDWMRAVPDLIRPWVPGEMTTLGADGFGFSDTRPAARRVFLVDAE
STVVATLAALARRGEIDESRVTEATARYRLDDVQAAGPQTSESGDA
NT seq
2841 nt
NT seq
+upstream
nt +downstream
nt
atgaggcagccggattggcgatcctccggcgagcacgcgcacgacgtcttcgaggagatc
cccttgaccccgcacaacaacgagaccggcggcgcgaactccccacagcgagtgcgggtg
atccgaaacggcctggctgcgcacctaccggacatcgcacccgacgaaaccgaggagtgg
ctcgagtcgttcaactcggtgctctccgtcgcgggcaagcagcgtgcccggtacctgatg
ctgcgcctgctgcagcgcgccggggagaccggagtgggcattccctccctgaccagcacc
gactacgtcaacacgatccccaccgagctggagccctggttccccggcgacgaggagacg
gagcgccgctaccgggcctggatgcgctggaacgccgcgatgatggtgcaccgcgcccaa
cgccccggtatcggcgtgggcgggcacatatcgtccttcgcctcctcggcgagcctctac
gaagtcgggttcaactggttcttccggggcaaggacgatccgggcggcggcgaccacctc
tacatccaggggcacgcctcacccggcatctacgcgcgggccttcctcgaaggacggctc
tcggccgaccagctcgacggcttccggcaggagtactcccacgcgggtccgggcgggggg
ctgccctcttatccgcacccccggctgatgccggggttctgggagttccccacggtctcg
atgggcctgtcgccgatgaacgcgatcttccaggcgaggttcaaccgctacctgcgtgac
cggggcatcaaggacaccagcgaccagcacgtctgggccttcctcggcgacggtgagatg
aacgagccggagtcgcgcgggatgctgcaggtggcggccaacgaggggttggacaacctg
acgttcgtggtcaactgcaacctgcagcagctggacgggccggtacggggcaacggcaag
atcatccaggagctggaggcgttcttccggggcgcgggctggaacgtgatcaaggtcatc
tgggggcgcgagtgggactcgctgctgcacgccgaccgggacggtgcgctgatcaacctg
atgaacagcaccccggacggggactaccagacctacaaggccaacgacggcgcgttcgtc
cgcgagcacttcttcggccgggacccgcgcaccaaggagatggtcaagaacttcaccgac
gaccagatctggggactccgcaggggcgggcacgactaccgcaagctctacgccgcctac
aaggcggcgatggagcaccacggccagccgacggtcatcctcgcgaaaacgatcaagggc
tacgggctcggagcccacttcgagggccgcaacgccacgcaccagatgaagaagctagcc
ctggacgacctcaaactgttccgggacagcctgcgcatcccgatctcggacgcgcagctg
gagcaggacccctacctcccgccctactaccacccgggtgaggacgccccggagatccag
tacctgcggcagcgccggagcaggctgggaggctacctgccggaacggcgcaccccggcc
aaaccgctggtgctgcccggcgacaaggtctacgacgtggtgcgccagggctcgggcaag
caggaagtggcgaccaccatggcgttcgtccggctgctcaaggacctcgccaaggacccc
gagatcgggccgaggctggtgccgatcatccccgacgaggcgcgcaccttcgggatggac
tcgatgtttccctcccagaagatctacaacccctccgggcagacctacacgccggtggac
taccagctgatgctggcctaccgggagagcgaccaggggcagatcctgcacgaggggatc
aacgaggcggggtcggtggcctcgttcaccgcggccgggacgagctacgccacccacggc
gagcccatgatcccggtctacatcttctactcgatgttcggtttccagcgcaccggcgac
gggctgtgggccgcgggcgaccagatggcgcggggcttcctgctcggagccaccgccggc
cgcaccaccctggtcggcgaggggctgcagcacgcggacggtcactcacagctgctggcc
gccacgaacccgggggtggtctcctacgacccggcgtgggcgttcgagatcgcccacata
gtccgcgacggcctgcgccggatgtacggggagcaaccggagaacgtcttctactacctc
accgtctacaacgagccctaccagcaacccgcggagcccgaggggatcgacgtcgacggc
ctgctgcgcggcctgtaccgctacaagcgggccgacggcgaacagggaccgagagcccaa
ctgttgacctcaggggtcgccatgccggaggtgctgcgcgcccagcggctgctcggcacc
gagtggggcgtgtccgccgacgtgtggtcggcgacctcctggacggaactccgccgggaa
gcggaggctgtggaccgggacaacctgctccacccggacgccgagcggcgcgagccttac
gtgacccgggtgctccggcccgagtcgggaccggtggtggcggtcagcgactggatgcgt
gccgtgccggacctgatccgtccgtgggtgcccggcgagatgaccacgctcggtgcggac
gggttcgggttctccgacacccgtccggcggcgcgacgggtcttcctggtggacgccgag
tcgactgtggtcgccacgctggccgctctggcacgtcgcggcgagatcgacgagtccagg
gtgaccgaggcgaccgcccggtaccggttggacgacgtccaggcggccgggccacagacc
tcggagtccggcgacgcctga
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