Amphiura filiformis: 140138347
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Entry
140138347 CDS
T10871
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
afil Amphiura filiformis
Pathway
afil01100
Metabolic pathways
Module
afil_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
Enzymes [BR:
afil01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
140138347
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
140138347
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
Polysacc_synt_2
NAD_binding_4
NAD_binding_10
GDP_Man_Dehyd
RmlD_sub_bind
KR
NmrA
Glyco_hydro_4
adh_short
Motif
Other DBs
NCBI-GeneID:
140138347
NCBI-ProteinID:
XP_072016354
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Position
17:6605475..6607511
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AA seq
391 aa
AA seq
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MSASDGTDSHPGFSSPWKIETHKLVAPKHFDVEPVDMHKEIVVVTGGSGFLGQHIVKHML
EQNEFPIREVRVFDMQPFEWCSGIGVTDSQVTLRQFQGDICNQAHLEKAFAGATVVIHNA
SVIDSSSIPDKERLHRINVQGTEAVIQTCVHTNVKYLIYTSSITAGERIGAYGVSKRLAE
DLVLQANGRQVKNGEKLRTCALRPVSIYGEGDLNFIPDKLIRNNTFYRIGDDAPRFQCAY
AGNVAWAFVAAVSRIHATHNKPSVGMTRGKALAGRYFCVADDTPVMSISGFLAQFAQHVG
AKISSFYIPFWLLYISAYFCEWVSYILSPFYTVRLPLSSMGVFSMCGMPITTYDMAKEYL
GYKPLYTYEEILPRLLRLHHEKYKSMDQASV
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgtcggcatcagatggaaccgattctcatcccggattttcctctccatggaaaattgaa
actcataaattagtggctccaaaacatttcgacgtcgagcctgttgatatgcacaaagaa
attgtggtagtaaccggtggttcgggattcttaggacagcatattgttaaacatatgctg
gaacaaaatgaattccccattcgtgaagtacgtgtgtttgatatgcaaccattcgaatgg
tgtagtggaattggagttactgacagtcaggttacactgcgtcaatttcaaggggacatt
tgcaatcaagctcatttagaaaaggcgtttgcaggtgctactgttgttatccacaatgcc
tcagtcatagacagttcgtcaattccagacaaagagagactgcaccgcataaatgtacaa
ggtactgaagctgtgattcaaacgtgtgttcacaccaacgtaaagtatctgatatatacc
agcagcatcactgccggagaaagaataggagcctatggagtaagtaaaaggctagcagag
gatctcgtacttcaagccaatggcagacaagtcaagaatggtgaaaaactacgcacttgc
gcacttcggcctgtttccatttatggtgaaggtgatctaaactttataccagacaagttg
ataagaaacaatactttctatcgaataggtgacgatgcaccaagatttcagtgcgcatat
gcaggtaatgttgcttgggcatttgtagcggctgtaagtcgtattcatgcgacgcacaac
aagcctagtgtaggtatgacacgcggcaaagcgttagccgggcgttatttctgtgtagca
gacgatacaccagttatgtctatcagtggctttctggcacaatttgcgcagcatgttggc
gcgaaaatatcctcattctatatacccttctggttactgtatatatccgcttatttttgc
gagtgggtgtcttatatcttaagccctttttacactgtaagactaccgttgtcaagtatg
ggggtcttttcaatgtgtggcatgccgataacgacatatgatatggcaaaagaatatttg
ggttataagccactgtacacttacgaagaaattttaccaagacttctgcgacttcatcat
gaaaagtataaatcaatggatcaggcgtccgtctag
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