Amphiura filiformis: 140168992
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Entry
140168992 CDS
T10871
Name
(RefSeq) NADPH-dependent 3-keto-steroid reductase Hsd3b5-like
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
afil Amphiura filiformis
Pathway
afil01100
Metabolic pathways
Module
afil_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
Enzymes [BR:
afil01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
140168992
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
140168992
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
Polysacc_synt_2
GDP_Man_Dehyd
NAD_binding_4
NAD_binding_10
KR
RmlD_sub_bind
adh_short
NmrA
Ldh_1_N
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-GeneID:
140168992
NCBI-ProteinID:
XP_072048390
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Position
14:complement(28089511..28095566)
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AA seq
384 aa
AA seq
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MADIMMNVDKFTSRQDKASMETIVVTGGCGFIGQHIVRQLMEQRLFPLKEIRIFDIQEFK
WFHGMEPYTNNSQATIKYVKGDIGDIDQLQSAFQDATTVIHSAADISVTTSPDIEKLQRV
NVKGTENVIQACINSNTERLVFTSSVDAFLPPEPFSTPEVTEEQVPKPHKFLMGPYAESK
FNANKLVLEANNKFLKNGKKLKTCALRIPFSYGEGDVQAKNYIRDAAKQKKLYLLGGDEN
IVQKIYAGNAAWAHVLAVHKLLSPDSAFSPAGKSIFIGDHTPFMSFSSHYKKFARRSGIA
IGPAIPIKVLYLISGFVDCVAWVLSPIYSLRVQMKWSGVSFVCNNYTVSWELSRRCLGYS
PIFSYKDSVERSWVYLKENDTDKE
NT seq
1155 nt
NT seq
+upstream
nt +downstream
nt
atggcagatattatgatgaatgtggataagtttacgagcagacaagataaagcctccatg
gagacaatagtggtaacaggtggatgtgggttcatcgggcaacatatcgtcagacaactg
atggaacagcgactatttccgctgaaagaaatacgcatctttgatattcaagaattcaaa
tggtttcatggaatggaaccttataccaacaacagccaggccacgatcaagtatgttaaa
ggtgatatcggtgatattgatcaactccaaagtgcgtttcaggacgcaacaaccgttatc
catagtgccgctgacatctccgtcacaacatcacctgatatagagaagcttcaacgggtc
aatgtgaaaggaacagaaaatgtaatccaagcatgcatcaacagtaacaccgaacgactt
gtttttaccagttccgtggatgcattcctaccacccgaaccattctcaactccagaagtc
accgaagaacaagttccaaaaccgcacaagttcctaatgggaccatacgccgaatcaaaa
ttcaacgccaataaattagtactggaggctaacaataaattcctgaagaatggaaaaaag
ctcaaaacgtgcgcattacggataccattctcatacggtgagggtgatgtacaagcgaaa
aattacatccgagatgccgcaaagcagaagaaattgtatctactcgggggagacgaaaac
atcgttcaaaagatttacgcgggtaacgcggcttgggctcacgtcttagcggtgcataaa
ttgttgagtcctgattctgcattttccccagcaggaaagagcattttcataggtgaccat
accccgttcatgtcttttagtagtcattacaaaaagtttgcaagacgtagtggaattgca
atcggtccagcgatacccatcaaagttctctacctaataagcggcttcgtcgattgcgta
gcttgggtgctatcgcccatctattccctgagagtgcaaatgaagtggtctggagtatcg
tttgtgtgtaacaattatacagtcagttgggagttatcccgtagatgcttaggttattca
cccattttttcctataaggattcagtggaaaggagctgggtctatctaaaggaaaatgat
actgataaagaatag
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