Amphiura filiformis: 140169339
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Entry
140169339 CDS
T10871
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 4-like
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
afil Amphiura filiformis
Pathway
afil01100
Metabolic pathways
Module
afil_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
Enzymes [BR:
afil01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
140169339
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
140169339
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Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
Polysacc_synt_2
GDP_Man_Dehyd
NAD_binding_10
Motif
Other DBs
NCBI-GeneID:
140169339
NCBI-ProteinID:
XP_072048695
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Position
14:29383096..29397640
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AA seq
361 aa
AA seq
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MAKGSNVTTLRQAWEIAFTEKVCVREIPGLKNHSASKSLSGLEPVAYNNNSKAKLKSIKG
DICELGQLSEACRDATAIIHSAAFIDVSSLQDEKKLHMVNVIGTDNVILSCFDNNIERLV
FTSTVDAYLPPTPFPTANVTELEAQTPSNFLMGSYGATKNKAEWLVMQHNRSPLQNGNLL
RTCALRIGCMYGEGDEITRNLMELPAKSKKNYPIGHDDHVIQKIYAGNAAWAHVLAVHKL
KDSSVFSPAGKSMFIEDDTPLKSLSAHFQPYVDGLGAVNSFRISFRLIYAVAAMMDFLSW
LLQPIYSIRSNITRSSILFCKNNYTMRSILARRCLGYKPLYTYDEGIARSIVYLKAALNV
Q
NT seq
1086 nt
NT seq
+upstream
nt +downstream
nt
atggctaagggcagcaatgtcacgacgcttagacaggcttgggagattgcatttacagag
aaggtctgcgtgagagagattccaggattgaagaatcactctgcaagcaaatctctgagt
ggactcgagcctgttgcgtacaacaataacagcaaagccaaactgaagagcattaaggga
gacatctgtgaacttggacaattgagcgaagcatgccgggatgcgaccgccatcatacac
agtgcggccttcattgatgtgtcgtcattgcaagatgaaaagaagttgcatatggtgaat
gtaataggaacagacaacgtcattctaagctgctttgataacaacattgagcgtctcgtc
ttcaccagtactgttgatgcatatttaccaccgacaccattccccactgctaatgttaca
gaactcgaagcacaaacaccttccaacttcctaatgggatcttacggagcaactaaaaac
aaagctgaatggttggtgatgcaacataatagatcaccgctgcaaaacggcaaccttctt
cgcacatgcgcactgcgtatagggtgcatgtacggcgaaggtgatgaaataacccgaaac
ctaatggagcttcctgctaagagtaagaagaactacccaataggtcatgatgatcatgta
atacagaagatatacgctggtaatgctgcatgggctcatgttttggcggtgcataagttg
aaggattcttctgttttctcgccggctggtaaaagcatgttcatagaggatgacactcca
ttgaaatcactatccgcacattttcagccttatgtagatggacttggtgcagtcaatagt
ttccgtatttcctttcgcttgatctacgcagtggcggctatgatggactttctctcctgg
ctactgcaaccgatctacagcatcagatctaacatcaccaggtcgtctatcctgttctgc
aagaacaactataccatgagatcgatactagcccgtcgatgtctaggttacaaaccactg
tatacatatgatgagggcattgcgaggagcatagtttatctcaaggctgctttgaatgtc
caataa
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