Amphiura filiformis: 140170475
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Entry
140170475 CDS
T10871
Name
(RefSeq) NADPH-dependent 3-keto-steroid reductase Hsd3b5-like
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
afil Amphiura filiformis
Pathway
afil01100
Metabolic pathways
Module
afil_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
Enzymes [BR:
afil01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
140170475
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
140170475
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
Polysacc_synt_2
NAD_binding_4
GDP_Man_Dehyd
NAD_binding_10
KR
RmlD_sub_bind
adh_short
NmrA
Ldh_1_N
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-GeneID:
140170475
NCBI-ProteinID:
XP_072049937
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Position
14:complement(28143719..28146369)
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AA seq
365 aa
AA seq
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METIVVTGGCGFIGQHIVRQLMEQRLFPLKEIRIFDIQEFNWFHGMQPGTNNSQATIKYV
KGDIDDIDQLQSAFQDATAVIHSAADISVTTSPDIEKLQRVNVKGTENVIQACINSSIER
LVFTSSVDAFLPPEPFSTPEVTEEQVPKPHTFLMGPYAESKFNADKIVLEANNKFLKNGK
KLKTCALRIPFIYGEGDVQAKNYIGDAAKQKKLYLLGAEENVVQKIYAGNAAWAHVLAVY
KLSRPDSAFSPAGKGIFIGDHTPFMSFSSHFKEFARRSGIAIGPTIPMKVLYLFGGFIDC
AAWVLSPIYSLRAEGKWSAIAFMDNNYTVSWQLSRRCLGYSPIFSYKDSIERSWIYLKKT
VIDKE
NT seq
1098 nt
NT seq
+upstream
nt +downstream
nt
atggagacaatagtggtaacaggtggatgtggattcatcgggcaacatatcgtcagacaa
ctgatggaacagcgactatttccgctgaaagaaatacgcatctttgatattcaagaattc
aactggtttcatggcatgcaacctggtaccaacaacagccaggccacgattaagtacgta
aaaggtgacatagatgatattgatcaactccaaagtgcgtttcaggacgcaacagccgtc
atccatagtgccgctgatatctccgtcacaacatcacctgatatagaaaagcttcaacgg
gtcaatgtgaaaggaacagaaaatgtaatccaagcatgcatcaacagtagcatcgaacgg
cttgtttttaccagttccgtggatgcattcctaccacccgaaccattctcaactccagaa
gtcaccgaagaacaagttccaaaaccgcacacgtttctaatgggaccatacgccgaatca
aaattcaacgccgataagatagtactggaggccaacaacaaattcctgaagaatggaaaa
aagcttaagacatgcgcattacggataccattcatatacggcgagggtgatgttcaagct
aaaaattacatcggggatgccgcaaagcagaagaaattgtatctactcggggcagaggaa
aacgtcgttcaaaagatttacgcgggcaacgcggcttgggctcatgtcttagcggtgtat
aaattgtcgcgtcccgattctgcattttccccagcaggaaagggcatcttcataggtgat
cataccccgttcatgtcttttagtagtcatttcaaagagtttgcaagacgtagtgggatt
gccatcggtccaacgatacccatgaaagttctgtacctatttggcggcttcatcgattgc
gcagcatgggtgttatcgccaatttattccctgagagcagaagggaagtggtctgcaata
gcatttatggataacaattatacagtcagttggcagttatcgcgtagatgcttaggctac
tcacccatattttcttacaaagattcgatagaaaggagctggatctatttaaagaaaact
gttattgataaagaataa
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