Acidaminococcus fermentans: Acfer_1305
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Entry
Acfer_1305 CDS
T01151
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
afn
Acidaminococcus fermentans
Pathway
afn00300
Lysine biosynthesis
afn00550
Peptidoglycan biosynthesis
afn01100
Metabolic pathways
afn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
afn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Acfer_1305
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Acfer_1305
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Acfer_1305
Enzymes [BR:
afn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Acfer_1305
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LUD_dom
Motif
Other DBs
NCBI-ProteinID:
ADB47666
UniProt:
D2RKR4
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All DBs
Position
complement(1439865..1441247)
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AA seq
460 aa
AA seq
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MLDAALLKRALQVPMALEDGEEFTDVVTDSRAIVPGCLFVALKGEKFDGHRFVAQALEDG
ARAAVVSEVPEGVAADRCVVVPDTLTAYQQIASRYRLDKKGLTVIAITGSNGKTSTKDCI
AAVLGERYRVIKTQANFNNEIGLPKTLLTIREDTEMAVVEMGMRGLGQIRAMKHIAYPDA
AVITNVGDTHLELLGSLENIAKAKSEILEDFTPKNHAFLNGDDPRVSVMETGAAVHTYGI
DSDADVKAVEISADGLRTVFTYRSRITGATQKVQLPLIGRHNVMNALAAVAVGEVYGVPD
AAIARGLENLKMTGMRQEILHFGPVTVINDAYNASPASMEAALRTLGDVVKSQGKGRAIA
VLADMLELGAHSQSGHAQVGTWCSQYGVTELVCYGPESRFMAEAAQKAGVPVHYAQDRGE
AARVLARLVRPDDVVLLKGSHGMEVFKLIDEVFRKGDAAC
NT seq
1383 nt
NT seq
+upstream
nt +downstream
nt
atgcttgatgctgctttgctgaaacgcgccctccaggtgcccatggccctggaagacgga
gaagaatttacggatgtggtaacggattcccgggccattgtgcccgggtgcctgtttgtg
gccctgaaaggggaaaagttcgacggccaccggttcgtggcccaggctctggaggacgga
gcccgggcggcggtggtgtcggaagtgccggagggcgtggccgctgaccgttgcgtggtg
gtgcccgataccctgacggcctaccagcagatcgccagccggtaccggctggacaaaaaa
ggcctgacggtgatcgccattaccggcagcaacggcaagacttccaccaaggactgcatt
gccgcagtgctgggggaaagataccgggtgatcaagacccaggccaacttcaacaacgaa
atcggtctgcccaagaccctgctgaccatccgggaagacacggaaatggctgtggtggaa
atgggcatgcggggcctgggacagatccgggccatgaagcatatcgcctatcctgatgcg
gcggtgatcaccaatgtgggggatacccatctggaactgctggggtccctggaaaacatc
gccaaagccaaaagcgagatcctggaagactttacgccgaagaaccatgccttcctcaac
ggggatgatccccgggtcagtgtgatggaaaccggtgccgcagtgcatacctacggcatc
gacagcgacgctgatgtgaaggcggtggaaatttctgccgacgggctccggaccgtgttc
acctaccggagcaggatcaccggagccacccagaaggtgcagctgcccctgatcggccgg
cacaatgtgatgaacgccctggcggcggtggccgtaggggaagtgtacggggtccccgat
gcagccattgcccggggcctggaaaacctgaagatgaccggcatgcgccaggagatcctc
cattttggcccggtgacggtgatcaacgatgcttacaacgccagcccggcatccatggaa
gcggctctccggaccctgggagatgtggtgaaaagccaggggaagggccgggccattgcg
gtgctggcggatatgctggaactgggggcccattcccaaagcggccatgcccaggtgggg
acctggtgcagccagtacggggtgacggaactggtgtgctacggaccggaaagccggttt
atggcggaagcggcccaaaaggccggggtgcccgtccactatgcccaggaccgtggggaa
gcggcccgggtgctggcccggctggtgcgtccggatgacgtggtgctgctgaaaggctcc
cacggcatggaagtgttcaaactgatcgacgaagtgttccggaagggggatgcagcatgc
tga
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