Actinoplanes friuliensis: AFR_08765
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Entry
AFR_08765 CDS
T02892
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase subunit E1
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
afs
Actinoplanes friuliensis
Pathway
afs00010
Glycolysis / Gluconeogenesis
afs00020
Citrate cycle (TCA cycle)
afs00620
Pyruvate metabolism
afs00785
Lipoic acid metabolism
afs01100
Metabolic pathways
afs01110
Biosynthesis of secondary metabolites
afs01120
Microbial metabolism in diverse environments
afs01200
Carbon metabolism
afs01210
2-Oxocarboxylic acid metabolism
Module
afs_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
afs00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
AFR_08765 (aceE)
00020 Citrate cycle (TCA cycle)
AFR_08765 (aceE)
00620 Pyruvate metabolism
AFR_08765 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AFR_08765 (aceE)
Enzymes [BR:
afs01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
AFR_08765 (aceE)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AGZ40042
UniProt:
U5VTE2
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All DBs
Position
complement(1901858..1904596)
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AA seq
912 aa
AA seq
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MATERKRPVISDGLPSQLPDIDPEETAEWVESLDGVIDEGGAKRARYVMLRLLERARERQ
VGVPPLTSTDYINTISPEQEPWFPGDEFVERRIRAYIRWNAAMLVHRAQRPEIGVGGHIS
TYASSASLYEVGMNHFFRGKDHPGGGDHIFFQGHASPGMYARAYLEGRLSENDLDGFRQE
LSHPGGGLPSYPHPRLMNNFWEFPTVSMGLGPLNAIYQARYNRYLHNRGIKDTSQQHVWA
YLGDGEMDEVESLGAIGLAAREELDNLTFVINCNLQRLDGPVRGNGKVIQELEAFFRGAG
WNVIKVVWGREWDTLLAKDTDGALVNLMNVTPDGDFQTYKGESGAFVRENFFGRDPRTRK
LVEGMTDDEIWGLKRGGHDYKKLYAAYKAATEHTGQPTVILAHTIKGWTLGSHFEARNAT
HQMKKLTLDDLKGFRDRLYLEISDKQLEENPYLPPYFHPGEKSDEMQYMLERRRELGGFV
PTRRTKHKSLAIPESKTFGDIKRGSGKQKVATTMAFVRLLKDLMRDKEFGARWVPIIPDE
ARTFGMDSLFPTKKIYSPHGQTYTSVDRELFLSYKESTTGQILHEGINEAGSTASFIAAG
TSYATHDEPMIPLYIFYSMFGFQRTADELWAAADQMTRGFLLGATAGRTTLNGEGLQHED
GHSLLIAATNPAVVAYDPAFAFEIAHIMENGLHRMYGEHQENVFYYLTIYNEPILQPVEP
SDVDVEGLLKGIYKYSPAPETTGPKAQVLASGTGMQWALKAQQLLAQDWGVGADVWSVTS
WTELRRDAMEIEEHNLLNPGDKPRKPYIETKLEGSEGPAIAVSDWMRAVPDLISRWIPND
YTSLGTDGFGMSDTRHALRRHFHVDAESIAVATLRQLALQGKVPAHVPAEAAKKYAIDDV
NAAPVGETGGDS
NT seq
2739 nt
NT seq
+upstream
nt +downstream
nt
gtggccacggaacgcaagcgcccggtgatcagcgacggcctgccgagccagcttccggac
atcgaccccgaggaaacagccgagtgggtcgagtcgctcgacggagtcatcgacgagggc
ggcgccaagcgcgcccgctacgtgatgttgcggctgctcgaacgggcgcgcgagcgacag
gtcggtgtcccgcccctgacctcgacggactacatcaacaccatctcgcccgagcaggag
ccgtggttccccggcgacgagttcgtcgagcggcggatccgggcgtacatccggtggaac
gccgcgatgctggtgcaccgcgcgcagcgcccggagatcggcgtcggcggccacatctcg
acctacgcgtcgtccgccagcctctacgaggtcggcatgaaccacttcttccggggcaag
gaccaccccggcggcggtgaccacatcttcttccagggccacgcctcccccggcatgtac
gcccgggcgtacctcgagggccggctcagcgagaacgacctggacggcttccgccaggag
ctctcgcacccgggtggcggcctgccgtcctacccgcacccgcggctgatgaacaacttc
tgggagttcccgacggtcagcatgggtctcggcccgctgaacgcgatctaccaggcgcgc
tacaaccgctacctgcacaaccgcgggatcaaggacaccagccagcagcacgtctgggcg
tacctcggcgacggcgagatggacgaggtcgagtcgctcggcgcgatcggtctcgcggcc
cgcgaggagctcgacaacctgaccttcgtcatcaactgcaacctccagcgcctcgacggg
ccggtccgcggcaacggcaaggtcatccaggagctcgaggcgttcttccggggcgccggc
tggaacgtcatcaaggtcgtctggggccgcgagtgggacaccctgctcgccaaggacacc
gacggcgcgctggtcaacctcatgaacgtcacgcccgacggcgacttccagacctacaag
ggcgagtccggcgcgttcgtccgggagaacttcttcggccgcgacccgcgtacgcgcaag
ctcgtcgagggcatgaccgacgacgagatctggggtctcaagcgcggcggccacgactac
aagaagctgtacgcggcctacaaggcggccaccgagcacaccggccagccgacggtcatc
ctggcgcacaccatcaagggctggacgctgggctcgcacttcgaggcccgcaacgccacg
caccagatgaagaagctgacgctggacgacctcaagggcttccgcgaccgcctctacctg
gagatctccgacaagcagctcgaggagaacccgtacctcccgccgtacttccacccgggt
gagaagtccgacgagatgcagtacatgctcgagcgccgccgggagctgggcggttttgtg
ccgacccggcgcaccaagcacaagtcgctggcgatcccggagtcgaagaccttcggcgac
atcaagcgcggctcgggcaagcagaaggtcgccaccaccatggcgttcgtccgcctgctc
aaggacctgatgcgcgacaaggagttcggtgcccgctgggtgccgatcattccggacgag
gcgcgcacgttcggcatggattcgctcttcccgaccaagaagatctactccccgcacggc
cagacctacacgtcggtcgaccgggagctcttcctgtcgtacaaggagtcgacgaccggg
cagatcctgcacgagggcatcaacgaggccgggtcgaccgccagcttcatcgcggccggc
acctcgtacgccacgcacgacgagccgatgatcccgctgtacatcttctactcgatgttc
ggcttccagcgcaccgccgacgagctgtgggcggccgcggaccagatgacccgtggcttc
ctgctgggcgcgaccgccgggcggaccacgctcaacggtgagggcctgcagcacgaggac
gggcactcgctgctgatcgcggcgacgaacccggccgtggtggcgtacgacccggcgttc
gcgttcgagatcgcgcacatcatggagaacggcctgcaccggatgtacggcgagcaccag
gagaacgtcttctactacctgacgatctacaacgagccgatcctccagccggtcgagccg
tccgacgtcgacgtcgagggcctgctcaagggcatctacaaatactctccggccccggag
acgacgggtccgaaggcgcaggtcctggcctccggcaccggcatgcagtgggcgctcaag
gcccagcagctgctggcccaggactggggtgtcggcgcggacgtgtggtcggtgacgtcc
tggaccgagctgcgccgcgacgcgatggagatcgaggagcacaacctcctcaaccccggt
gacaagccgcgcaagccgtacatcgagaccaagctggagggctcggagggcccggccatc
gcggtcagcgactggatgcgggccgtgcccgacctgatcagccgctggatcccgaacgac
tacacgtcgctcggcaccgacggtttcggcatgagcgacacccggcacgcgctgcgccgc
cacttccacgtggacgcggagtcgatcgccgtggcgacgctgcgccagctcgcgctccag
ggcaaggtgccggcgcacgtaccggccgaggcggccaagaagtacgcgatcgacgacgtc
aacgccgcgcccgtgggcgagaccggcggcgacagctga
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