Actinoplanes friuliensis: AFR_37970
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Entry
AFR_37970 CDS
T02892
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
afs
Actinoplanes friuliensis
Pathway
afs00020
Citrate cycle (TCA cycle)
afs00630
Glyoxylate and dicarboxylate metabolism
afs00785
Lipoic acid metabolism
afs01100
Metabolic pathways
afs01110
Biosynthesis of secondary metabolites
afs01120
Microbial metabolism in diverse environments
afs01200
Carbon metabolism
afs01210
2-Oxocarboxylic acid metabolism
Module
afs_M00009
Citrate cycle (TCA cycle, Krebs cycle)
afs_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
afs00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
AFR_37970 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
AFR_37970 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AFR_37970 (kgd)
Enzymes [BR:
afs01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
AFR_37970 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
AFR_37970 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
AFR_37970 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
AFR_37970 (kgd)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
OxoGdeHyase_C
2-oxoacid_dh
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AGZ45848
UniProt:
U5W9F8
LinkDB
All DBs
Position
8282042..8285785
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AA seq
1247 aa
AA seq
DB search
MSTQQTSHDNPLADFGPNEWIVDEMYQRYLADPTSVDPAWHDFFADYKPAMASGSIATPD
EATAANAKATAAKAGTDAPAASTIAPEKPTVPAAPEKPAAPPAAAPAPAPAKPAPKPAPA
AAKTPAPAEGSKVTTLRGVAARIVQNMDASLEVPTATSVRAVPAKLLVDNRIVINNHLAR
GRGGKVSFTHLIGWALIRSVMAHPEMNNSFAEVDGKPALVQPEHINLGIAIDLAKKDGSR
ALVVPSIKNCEKMDFRKFWQAYEDVVRRARRNELTMDDYAGTTISLTNPGGIGTVHSIPR
LMAGQSAIIGVGAMEYPAPYSGMSDETLTEHGVSKVTTLTSTYDHRVIQGAQSGEFLKAM
HEFLLGEHDFYDDIFTSLRIPYEPVRWVRDVARTSEGQIDKAARVVELIHAYRVRGHLMA
DTDPLEFEIRRHPDLDVLQHGLTLWDLDRLFPVGGFAGKQKMKLRDVLGVLRDTYCRRVG
IEYMHIQGPEERRWIQDRIEIKYTKPSPEEQKHVLNRLNAAEAFETFLQTKFVGQKRFSL
EGGESLIPLLDEVLQASAEGGLDEMVIGMAHRGRLNVLANIVGKPYEKIFNEFEGQMDPK
SAHGSGDVKYHLGQTGKYTAPDEEHSTTVSVVANPSHLEAVDPVLEGIVRAKQDRLDLGL
HGYTVLPVLIHGDAAFAGQGVVAETLNLSQLRGYRTGGTVHVVVNNQVGFTTAPEYSRSS
LYSTDVARMIQAPIFHVNGDDPEAVVRVARLAFEYRQAFNKDVVIDLVCYRRRGHNEGDD
PSMTNPRMYQIIDTKRSVRKLYTEELIGRGDLTVDDAQEQLRDYQSQLEKVFKATRDTAG
SAPRPRRNLADEPEPQVDTAVDAAGVRAVGQAHLDLPEGFTPHKRVQQLLDRRAKMSADG
GIDWGMGELIAFGSLLAQGVTVRLAGQDSRRGTFTSRHAAIVDSKTGNDFLPLSTLATGN
ARFFAHDSLLSEYAAMGFEYGYSVENPEALVLWEAQFGDFVNGAQSIVDEFISSGEVKWG
QMSSLVLLLPHGQEGQGPDHSSGRPERFLQLCAQDNMRVANPTTPANYFHLLRRQALSSK
RKPLIVFSPKSLLRHKLAVSSVADFTEGTFQPIIGDAGVNGTPLDAGSVKRVLLCSGKVY
YDLFQARAERGITDTAIIRMEQIYPLPVEELKAVLNQFPNAEDFAWVQEEPANQGAWSFV
ALNLLEHLEGVRLRRISRPAAAAPAVGSAKMHDAEQSALVEAALPRP
NT seq
3744 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgacccagcagacttcgcatgacaatccactcgcggacttcggccccaacgagtgg
atcgtcgacgagatgtaccagcgctacctggccgatccgaccagcgtcgaccccgcctgg
cacgattttttcgccgactacaagccggccatggcctcgggttcgatcgctacaccggac
gaggcgaccgccgccaacgcgaaggcgacggctgccaaggccggcaccgacgccccggca
gcctcgacgatcgctccggagaagccgaccgtccccgccgctcccgagaagccggccgcg
cctcccgcggctgcacccgcgcccgctcccgccaagccggcccccaagcctgctcccgcg
gccgccaagacccccgctccggcggaagggtccaaggtcaccacgctgcgcggcgtcgcc
gctcgcatcgtccagaacatggacgcctcgctggaggtgccgaccgcgacgtcggtgcgg
gccgtgccggccaagctgctggtcgacaaccgcatcgtgatcaacaaccacctcgcccgc
gggcgtggcggcaaggtcagcttcacccacctgatcggctgggcgctgatccgctcggtg
atggcccacccggagatgaacaactccttcgccgaggtggacggcaagccggcactggtc
cagcccgagcacatcaacctcggcatcgccatcgacctcgccaagaaggacggcagccgc
gcgctggtcgtgccgtccatcaagaactgcgaaaagatggacttccgcaagttctggcag
gcgtacgaggacgtggtccgccgcgcccgccgcaacgagctgaccatggacgactacgcc
gggacgacgatctcgctgaccaaccccggcggcatcggcaccgtgcactccatcccgcgc
ctgatggccgggcagagcgccatcatcggcgtcggcgccatggaataccccgcgccctac
tccggcatgtccgacgagaccctgaccgagcacggcgtcagcaaggtcaccacgctgacc
agcacctacgaccaccgggtcatccagggtgcgcagtcgggcgagttcctcaaggcgatg
cacgagttcctgctcggcgagcacgacttctacgacgacatcttcacgtcgctgcggatc
ccgtacgagccggtgcgctgggtgcgggacgtcgcccgcacctccgagggccagatcgac
aaggccgctcgggtggtcgagctcatccacgcgtacagggtgcgcggtcacctgatggcc
gacaccgacccgctcgagttcgagatccgccggcaccccgacctggacgtgctccagcac
gggctgaccctgtgggacctcgaccggctgttcccggtcggcggcttcgccggcaagcag
aagatgaagctgcgtgacgtcctcggcgtcctgcgcgacacctactgccgccgggtcggc
atcgagtacatgcacatccagggtcccgaggagcggcgctggatccaggaccgcatcgag
atcaagtacacgaagccgtcgccggaggagcagaagcacgtcctcaaccggctgaacgcg
gccgaggcgttcgagaccttcctgcagaccaagttcgtcgggcagaagcgcttctcgctc
gagggcggcgagtcgctgatcccgctgctcgacgaggtgctccaggcgtccgccgagggt
ggcctcgacgagatggtcatcggcatggcgcaccgcggccggctcaacgtgctcgcgaac
atcgtcggcaagccgtacgagaagatcttcaacgagttcgagggtcagatggacccgaag
tcggcccacggctccggtgacgtcaagtaccacctgggccagaccgggaagtacaccgcg
cccgacgaggagcactcgacaaccgtcagcgtggtggcgaacccgtcgcacctcgaggcc
gtggacccggtgctcgagggcatcgtccgcgccaagcaggaccgcctcgacctcggcctc
cacggatacaccgtgctgccggtcctcatccacggcgacgccgcattcgcgggccagggt
gtggtcgccgagacgctcaacctctcccagctgcgcggataccgtacgggcggcacggtg
cacgtggtcgtcaacaaccaggtcggcttcaccaccgccccggagtacagccgctcgtcg
ctctactcgaccgacgtcgcgcgcatgatccaggcgccgatcttccacgtgaacggtgac
gaccccgaggccgtcgtccgggtggcacggctggcgttcgaataccgccaggcgttcaac
aaggacgttgtcatcgacctggtctgctaccgccgccgcggtcacaacgagggtgacgac
ccctcgatgaccaacccgcggatgtaccagatcatcgacacgaagcgctcggtccggaag
ctctacaccgaggagctcatcggccgcggagacctcaccgtggacgacgcccaggagcag
ctgcgcgactaccagtcgcagctggagaaggtgttcaaggcgacccgggacaccgcgggc
tccgcgccacggccccgccgcaacctcgcggacgagccggagccgcaggtcgacaccgcg
gtcgacgccgccggtgtgcgtgccgtcggccaggcccacctggacctgccggagggcttc
acgccgcacaagcgggtccagcagctgctggaccgacgcgccaagatgtccgccgacggc
ggcatcgactggggcatgggcgagctgatcgccttcggctcgctgctggcccagggcgtc
acggtccggctcgccggccaggactcccgccggggcaccttcacctcccggcacgcggcg
atcgtcgactcgaagacgggcaacgacttcctgccgctgtccacgctggcaaccggcaac
gcccgcttcttcgcccacgactccctgctcagcgagtacgccgcgatgggcttcgagtac
ggctactcggtcgagaaccccgaggccctggtgctgtgggaggcgcagttcggcgacttc
gtcaacggcgcccagtcgatcgtcgacgagttcatctcctccggcgaggtcaagtggggc
cagatgtcgtcgctggtgctgctgctcccgcacggccaggaaggacagggcccggaccac
tcgtcgggccgcccggagcggttcctgcagctctgcgcgcaggacaacatgcgggtcgcc
aacccgaccaccccggcgaactacttccacctgctgcgccggcaggccctctccagcaag
cgcaagccgctgatcgtcttctccccgaagtcgctgctgcgccacaagctggcggtgtcg
tcggtcgccgacttcaccgagggcaccttccagccgatcatcggcgacgccggtgtcaac
ggcacgccgctggacgccggctcggtgaagcgcgtcctgctctgctcgggcaaggtctac
tacgacctgttccaggcccgcgccgagcgaggcatcaccgacacggcgatcatccggatg
gagcagatctacccgctgcccgtcgaggagctcaaggccgtgctcaaccagttcccgaac
gcggaggacttcgcgtgggtccaggaggagccggccaaccagggtgcgtggtccttcgtg
gccctcaacctcctcgagcacctcgaaggcgtgcgcctgcgccggatctcccggcccgcc
gcggccgccccggcggtcggctccgccaagatgcacgacgccgagcagtcggctctggtc
gaggcggcgctcccgcgcccgtga
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