KEGG   Addendum: AAC68816
Entry
AAC68816          CDS       T10000                                 
Symbol
fkbP
Name
(KEGG) pipecolate-incorporating enzyme
  KO
K16378  pipecolate-incorporating enzyme
Taxonomy
TAX:82632
  Lineage
Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces
Organism
Streptomyces sp. MA6548
SSDB
Motif
Pfam: Condensation AMP-binding PP-binding AMP-binding_C
Other DBs
NCBI-ProteinID: AAC68816
GB: AF082100
UniProt: Q9ZGA6
LinkDB
AA seq 1504 aa
MTSRGKRPGTLRLGGSPKKRNSTNREIVAADRAEPLLASFAQRRIWFLQQLDPDSNAYNL
PLVRRLTGPLDAALLERALTLVVARHEALRTVFDAPDGEPVQRVLPAPPRILRHARADGE
QGAARLVHDEIAAPFDLSTGPLIRALLIRVGDDDHVLAVTVHHVAADGWSFGLLQLELAA
HCTALRDTSRPAVLPPLPLRYADFAAWERRELTGAGLEKRLAYWRDRLRGAPAVLDLPTD
RPRPPVADADAGLVEWRPPAELAAAVRRIGRDAGTSAFMTLLSAFQLVLARHAGTRDVLV
GTPVANRTRTEFEGVIGMFVNTLALRGDLSGDPSFRELLDRCRATAADAFAHADLPFENL
IEVLAPDRDLSVNPVVQVLLQVLRRDASAPALPGVTAEPFGTGRWFTRFDLEFHVYEEAD
GALTGELLYSRALFDESRITRLLDEFTAVLRAATAAPGTRLSQLPGAEATPTPEIPSNDT
ARELPVDTLPELLARYAARTPDAVAVTDPCTSLTYGELDRRANRLAHLLRARGTVTGDLV
GICADRGVDLVVGIVGILKAGAAYVPLDPEHPPERTDFVLADARLTAVVAHETYRHRFSG
VPHVVTPDDPDLGRQPDTAPHLTLGRDSLAYAIYTSGSTGKPKAVLMPGVSAVNLLLWQE
RTMGREPASRTVQFVTATFDYSVQEIFSALLGGTLVIPPDEARFDPPGLARWMDEQAITR
IYAPTAVLRALVEHVDPHSDQLSALRHLCQGGEALALDARLRELCRHRPHLRVHNHYGPA
ESQLITGYTLPADPDTWPAAAPIGRPIDNTRIHLLDDALRPVPDGMPGQLCVAGIGLARG
YLARPELTAERWVSGGATGEERMYLTGDLARRAPGGDLDFLGRIDDQVKIRGIRIEPGEV
ENVLAEDARVAHAAVSVREDPRGEKFLAAYVVPTAGPHGDGLAASLREGLADRLPAYLVP
SAVVVMDALPRTTSGKVDRRALPDPAPGPASPRKVAPRNRAERVVCRIFQDVLDVPQVGI
DDEFFALGGHSLLATRVVSRIRAELGADVALRTLFDARTPAALARAVDEAGPAALPPILS
SPCAGPAPITAAQEQMLHSHGSLLAAPSYTVAPYGFRLRGPLDRDALDAALTRITARHEP
LRTGFRGREQIVGPPAAVCAEVVEVPSGDVGAAARVARAELARPFDLVAGPLLRAVLLPL
GAEDHVLLLMLHHLAGDGWSFDLLVRELSGASPDLPVSYPDVARWERVPAVVAARENDRA
YWRRQFEGACAPELPTVRPRGTAAPDGRAFLWTLDDATVAAARRVADARNATWHETVLGA
FALVVAEAADTDDVLVATPFADRGYAGTDHLIGFFAKVLALRIDVGSGTGGTPSFAEVLR
RVHATMTGAHAHQSVPYSAMRAADPALPPTPVSFQLISALSTELRLPGLRTEPFPVVTET
VDEINGELSVNLFDDGHTVSGAVVHDAALLDRATVDDLLTRVESTLRAAAGDLTVRVTGQ
VGSE
Reference
PMID:9780228
  Authors
Motamedi H, Shafiee A
  Title
The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506.
  Journal
Eur J Biochem 256:528-34 (1998)
DOI:10.1046/j.1432-1327.1998.2560528.x

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