Entry
Symbol
aknS
Name
(KEGG) aklavinone 7-alpha-L-rhodosaminyltransferase (EC:2.4.1.326)
KO
Taxonomy
Lineage
Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces
Organism
Streptomyces galilaeus
Taxonomy
SSDB
Ortholog Paralog GFIT
Motif
Motif
Other DBs
LinkDB
All DBs
AA seq
443 aa AA seq DB search
MRVLLTSFALDAHFNGSVPLAWALRAAGHEVRVASQPALTASITAAGLTAVPVGADPRLD
EMVKGVGDAVLSHHADQSLDADTPGQLTPAFLQGWDTMMTATFYTLINDDPMVDDLVAFA
RGWEPDLILWEPFTFAGAVAAKVTGAAHARLLSFPDLFMSMRRAYLAQLGAAPAGPAGGN
GTTHPDDSLGQWLEWTLGRYGVPFDEEAVTGQWSVDQVPRSFRPPSDRPVVGMRYVPYNG
PGPAVVPDWLRVPPTRPRVCVTLGMTARTSEFPNAVPVDLVLKAVEGLDIEVVATLDAEE
RALLTHVPDNVRLVDHVPLHALLPTCAAIVHHGGAGTWSTALVEGVPQIAMGWIWDAIDR
AQRQQALGAGLHLPSHEVTVEGLRGRLVRLLDEPSFTAAAARLRAEAESEPTPAQVVPVL
ERLTAQHRAREPRRPGGTSPCVS
Reference
Authors
Raty K, Kunnari T, Hakala J, Mantsala P, Ylihonko K
Title
A gene cluster from Streptomyces galilaeus involved in glycosylation of aclarubicin.
Journal
Reference
Authors
Lu W, Leimkuhler C, Gatto GJ Jr, Kruger RG, Oberthur M, Kahne D, Walsh CT
Title
AknT is an activating protein for the glycosyltransferase AknS in L-aminodeoxysugar transfer to the aglycone of aclacinomycin A.
Journal
Reference
Authors
Leimkuhler C, Fridman M, Lupoli T, Walker S, Walsh CT, Kahne D
Title
Characterization of rhodosaminyl transfer by the AknS/AknT glycosylation complex and its use in reconstituting the biosynthetic pathway of aclacinomycin A.
Journal