Entry |
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Symbol |
aknOx
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Name |
(KEGG) bifunctional aclacinomycin-N/aclacinomycin-A oxidase (EC:1.1.3.45 1.3.3.14)
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KO |
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Taxonomy |
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Lineage |
Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces |
Organism |
Streptomyces galilaeus
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SSDB |
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Motif |
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Other DBs |
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Structure |
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LinkDB |
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AA seq |
545 aa
MFVLNEFTRRGFLGTAAAVGGTTVVTTALGGAPAAQAAVPEAADGGACGARTALVKVDRV
DRRYQDLVTRGFNGRFRGRPDVVYVVHTADQVVDAVNQAMAAGQRIAVRSGGHCFEGFVD
DPAVRAVIDMSQMRQVFYDSGKRAFAVEPGATLGETYRALYLDWGVTIPAGVCPQVGVGG
HVLGGGYGPLSRRDGVVADHLYAVEVVVVDASGRARKVVATSAADDPNRELWWAHTGGGG
GNFGIVTRYWFRTPGATGTDPSQLLPKAPTSTLRHIVTWDWSALTEEAFTRIIDNHGAWH
QSNSAAGTPYASMHSVFYLNSRAAGQILLDIQIDGGLDGAEALLNDFVAAVNEGTGVEPA
VQRSTEPWLRATLANKFDTGGFDRTKSKGAYLRKPWTAAQAATLYRHLSADSQVWGEVSL
YSYGGKVNSVPETATATAQRDSIIKVWMSATWMDPAHDDANLAWIREIYREIFATTGGVP
VPDDRTEGTFINYPDVDLVDERWNTSGVPWYTLYYKGNYPRLQKVKARWDPRDVFRHALS
VRPPG |
Reference |
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Authors |
Raty K, Kantola J, Hautala A, Hakala J, Ylihonko K, Mantsala P |
Title |
Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster. |
Journal |
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Reference |
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Authors |
Alexeev I, Sultana A, Mantsala P, Niemi J, Schneider G |
Title |
Aclacinomycin oxidoreductase (AknOx) from the biosynthetic pathway of the antibiotic aclacinomycin is an unusual flavoenzyme with a dual active site. |
Journal |
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