Addendum: AFB74617
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Entry
AFB74617 CDS
T10000
Symbol
CYP82Y1
Name
(KEGG) (S)-N-methylcanadine 1-hydroxylase (EC:1.14.14.166)
KO
K20621
(S)-N-methylcanadine 1-hydroxylase [EC:
1.14.14.166
]
Taxonomy
TAX:
3469
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; Ranunculales; Papaveraceae; Papaveroideae; Papaver
Organism
Papaver somniferum
Taxonomy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
p450
Motif
Other DBs
NCBI-ProteinID:
AFB74617
GB:
JQ659005
UniProt:
I3PLR1
A0A4Y7LGW8
LinkDB
All DBs
AA seq
556 aa
AA seq
DB search
MAYLMIKKSIYLFFDQPTAVGTLILAFLLTLSPVIIYYEQKKRGLRRNRTAITTTPLPEA
SGAWPVIGHLLLFMNENDLNHVTLGHMADKYGPIFSLRFGRHRTLVVSSWEMVKECFTGT
NDKLFSNRPSSLAVKLMFYDTESYGFAPYGKYWRELRKISTHKLLSNQQLEKFKHLRISE
VDNSFKKLHELCSNNKQGGDTTYVASLVRMDDWFAYLTFNVIGRIVSGFQSNAVAGATNS
QEKYKLAIDEVSNLMATFAVSDVVPRLGWIDRLTGLTGKMKNCGKKLDAVVGDAVEDHRQ
KKLKISRNNTGALTEHEEEDFIDVCLSIMEQSQIPGNHPEISVKSIALDMLSGGSDTTKL
IMTWTLSLLLNHPDILDKAKEEVDTYFGKKKISDNTPVVDAADVPNLVYIQAIIKESMRL
YPASTLMERMTSDDCDVGGFHVPAGTRLWVNVWKMQRDPRVWKDPLVFLPERFLSNDKGM
VDVKGQNYELIPFGTGRRICPGASFALEVLHLVLTRLILEFEMKAPEGKIDMRARPGFFH
NKVVPLDVQLTPRTLD
Reference
PMID:
22653730
Authors
Winzer T, Gazda V, He Z, Kaminski F, Kern M, Larson TR, Li Y, Meade F, Teodor R, Vaistij FE, Walker C, Bowser TA, Graham IA
Title
A Papaver somniferum 10-gene cluster for synthesis of the anticancer alkaloid noscapine.
Journal
Science 336:1704-8 (2012)
DOI:
10.1126/science.1220757
Reference
PMID:
24324259
Authors
Dang TT, Facchini PJ
Title
CYP82Y1 is N-methylcanadine 1-hydroxylase, a key noscapine biosynthetic enzyme in opium poppy.
Journal
J Biol Chem 289:2013-26 (2014)
DOI:
10.1074/jbc.M113.505099
DBGET
integrated database retrieval system
