KEGG   Addendum: AKM12282
Entry
AKM12282          CDS       T10000                                 
Symbol
CYP71D1V2
Name
(KEGG) tabersonine 3-oxygenase (EC:1.14.14.50)
  KO
K22365  tabersonine 3-oxygenase [EC:1.14.14.50]
Taxonomy
TAX:4058
  Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Organism
Catharanthus roseus
SSDB
Motif
Pfam: p450
Other DBs
NCBI-ProteinID: AKM12282
GB: KP122967
UniProt: I1TEM1
LinkDB
AA seq 506 aa
MEFHESSPFVFITRGFIFIAISIAVLRRIISKKTKTLPPGPWKLPLIGNLHQFLGSVPYQ
ILRDLAQKNGPLMHLQLGEVSAIVAASPQMAKEITKTLDLQFADRPVIQALRIVTYDYLD
ISFNAYGKYWRQLRKIFVQELLTSKRVRSFCSIREDEFSNLVKTINSANGKSINLSKLMT
SCTNSIINKVAFGKVRYEREVFIDLINQILALAGGFKLVDLFPSYKILHVLEGTERKLWE
IRGKIDKILDKVIDEHRENSSRTGKGNGCNGQEDIVDILLRIEEGGDLDLDIPFGNNNIK
ALLFDIIAGGTETSSTAVDWAMSEMMRNPHVMSKAQKEIREAFNGKEKIEENDIQNLKYL
KLVIQETLRLHPPAPLLMRQCREKCEIGGYHIPVGTKAFINVWAIGRDPAYWPNPESFIP
ERFDDNTYEFTKSEHHAFEYLPFGAGRRMCPGISFGLANVELPLALLLYHFNWQLPDGST
TLDMTEATGLAARRKYDLQLIATSYA
Reference
  Authors
Qu Y, Easson ML, Froese J, Simionescu R, Hudlicky T, De Luca V
  Title
Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast.
  Journal
Proc Natl Acad Sci U S A 112:6224-9 (2015)
DOI:10.1073/pnas.1501821112

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