Actinomyces graevenitzii: M3I41_02915
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Entry
M3I41_02915 CDS
T08387
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
agh
Actinomyces graevenitzii
Pathway
agh00020
Citrate cycle (TCA cycle)
agh00630
Glyoxylate and dicarboxylate metabolism
agh00785
Lipoic acid metabolism
agh01100
Metabolic pathways
agh01110
Biosynthesis of secondary metabolites
agh01120
Microbial metabolism in diverse environments
agh01200
Carbon metabolism
agh01210
2-Oxocarboxylic acid metabolism
Module
agh_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
agh00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
M3I41_02915
00630 Glyoxylate and dicarboxylate metabolism
M3I41_02915
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
M3I41_02915
Enzymes [BR:
agh01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
M3I41_02915
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
M3I41_02915
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
M3I41_02915
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
M3I41_02915
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GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
UQF80244
UniProt:
A0A9E7AKD8
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All DBs
Position
complement(687298..691047)
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AA seq
1249 aa
AA seq
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MPYKEQLTVSENDFAQGFGTNEWIVEDMREAYLADPASVTQSWREFFSENPQYLAGQSPA
MPSKPLSASVGVQIPGATTASASRRPVLASEDVSRSDLPPAPTAQFKSPTSPYAYNQAHS
DASETSNGVVESVDTLKGASARTAKNMEASLQIPTATSARAIPAKVLIENRLLINTHLAS
TRGGKVSFTHLIAWALVESLAEMPEMNVAYTLDEKGKPALHNPAHVNLGLAIDVPSANGE
RRLLVPSVKNADTLDLASFIDAYDALVVRARKGQLTVDDFKDTTATLTNPGMIGTLNSVP
RLMPGQGLIMGVGAMTYPAAFAGASPETLARQAVGKVLTLSNTYDHRVIQGAQSGELLRL
MERKLMGLDGFWNRSFKALRIPHEPVHWDQDVTYDPLADAGKPARVAELIHAFRQRGHLA
ADTDPLAYRLRRHPDLNFSSYGLSLWDLDRVFPTGGLGGKDRATLREILQMLRDAYSRYV
GVEYMHIQDPAQRRWWQERMEGVTPSIDTAERRRILTKLMQAEAFEVFLQTKYVGQKRFS
LEGGESLIVLLDRLIDDAAHDGIEEAAIGMAHRGRLNVLTNIAGKSYGQVFDEFDGNYLT
NGQGSGDVKYHLGTTGTFTGTDDVTTKVSLAANPSHLETVDGVLEGIVRAKLDRSGSGAD
GSYNVLPILVHGDAAFAGQGVVYEVLNMSQLPGYHTGGTIHVIVNNQIGFTTGNALGRST
TYPSDLAKGLQVPIFHVNGDAPESVARVARWAWEYRQEFHKDVIIDLVCYRRRGHNEGDD
PSMTQPVMYNLIDRKPSTFSVYTTNLVGRGDLTEEQCEQLLDAYRDNLEHILNEARAGHL
NADTPAYSGPKAGETSHSQPTAVAREVIERIGDAQVSVPEGFQVHSKLMNLLRKRQSMSR
QGGIDWGFGELLAFGSLLMEGVPVHMTGEDVRRATFAQRHAVMHDQRNGSEWTPLDYLTP
NQAKLSIVDSLLSEYGAMAFEYGYSVERSEGLNIWEGQFGDFANGAQTVIDEYVSSAEQK
WGQHSGLVLLLPHGLEGQGPDHSSARIERYLQLCAQDNMRVVQPSTPANHFHTLRDQARR
EPRRPLILISPKQMLRLKAAVSPVEDFISGGMQTVIGENDPEVLAAAAANKVDRVLLCSG
RIYWDLLAHRQHAEDKHTAIVRLEQLYPLDEPALLEALAPFAGAELVWVQDEPRNQGAWP
WLALHLPDSITAGRLPRVVARPEAAAPAVGTSAAHVAQQKLLLDEAFAR
NT seq
3750 nt
NT seq
+upstream
nt +downstream
nt
atgccatataaggagcagctaaccgtgtctgagaacgacttcgctcagggctttggcacc
aacgaatggattgtcgaggatatgcgggaggcttacctagccgacccggcctcagtaacc
caatcatggcgcgagtttttcagcgaaaacccgcagtatctagcaggccagtcgccggcc
atgccctcaaagccgcttagcgctagcgttggcgtgcaaatccctggtgctaccaccgcc
tccgctagccgacgccccgtcttggccagtgaggatgtttcccgctctgacctgcccccc
gcccccacagcccagttcaagtcccccacctccccttatgcctacaaccaggcgcatagt
gacgctagcgaaactagtaacggcgtggtggaaagcgttgacaccctaaagggagccagc
gcccgcaccgctaagaatatggaggcttccctccagattcctaccgctacttctgcccgt
gctatcccggctaaggtgctgattgaaaaccgtctgctaatcaacactcacctagcttcc
acgcgtggtggcaaggtttccttcactcacctgatcgcttgggccctggtggagtctctg
gcagagatgccggaaatgaatgtggcttacaccctggacgaaaagggcaagccggcgcta
cacaaccccgcccacgtaaacctgggtctggcaattgacgtgcccagcgctaacggtgag
cgtcgcctgctggtccccagcgttaagaacgccgacaccctagacctagctagtttcatt
gacgcctatgacgcactggtagttagagcccgcaagggtcagctaactgtcgatgacttc
aaggacaccaccgccaccctgaccaaccccggcatgatcggcacccttaactctgtgccg
cgcctaatgcccggtcagggcctaatcatgggtgtaggcgccatgacctacccggccgcg
tttgctggtgccagccctgaaaccctagcccgccaggctgtaggcaaggtcttgacactg
tctaacacctacgatcaccgcgtcatccagggcgcccagtccggcgagctactgcgtcta
atggaacgcaagctcatgggcctagatggcttctggaaccgctccttcaaagcgctacgt
atcccccacgaaccggtgcactgggaccaagacgtcacctacgacccgctagccgacgcc
ggcaagcccgcccgtgtagctgagctgattcacgctttccgtcagcgcggacacctagcc
gccgacactgacccgctggcctaccgcctacgccgtcaccctgacctgaacttctcctcc
tacgggctaagcctgtgggacctggacagggtcttccccaccggtggtctaggtggcaag
gaccgcgccaccttgcgcgaaattttgcagatgctgcgtgacgcctactcgcgttatgtg
ggcgtggaatacatgcatatccaagacccagcccagcgtcgctggtggcaagaacgcatg
gaaggtgttactcccagcattgatactgctgagcgccgtcgcatcctaaccaagctgatg
caggcagaagccttcgaagtgttcttgcaaaccaagtacgtgggccaaaagcgcttctcg
ctagaaggtggcgagtcactgattgtgctgctggaccgcctgatcgacgacgccgcacat
gatggcattgaagaagccgctattggtatggcccaccgtggccgcctaaacgtgcttacc
aatattgccggcaagtcttacggccaagtctttgacgagtttgacggtaactacctgacc
aacggccagggttctggtgacgtcaaataccacctgggcaccaccggcaccttcaccggc
accgatgatgtgaccaccaaggtttccctggctgccaacccctcccacctggagacagta
gatggggtgctggaaggtattgtgcgcgccaagctagatcgcagcggctccggcgctgac
ggcagctacaatgttttgccgattttggtgcatggtgacgccgcatttgcaggccagggc
gtggtttacgaagtgctcaacatgagccagctacccggttaccacaccggcggcactatc
cacgtgatcgtcaacaaccagatcggtttcaccaccggtaacgcgctgggacgctccacc
acctacccctcggacctggctaaggggctacaggtgccgatcttccacgtaaacggtgac
gcccccgaatctgtggcacgcgtagcccgctgggcttgggaataccgccaagaattccac
aaggacgtcattatcgatctggtttgctaccgccgtcgtggtcacaacgagggtgacgac
ccctcaatgacccagccggttatgtacaacctgatcgaccgcaagccctccaccttctcg
gtttacaccaccaacctggtggggcgcggagacctcactgaagaacagtgcgagcagcta
ctggacgcctaccgcgacaacctggagcacatccttaacgaggcccgcgccggtcacctc
aatgctgacacccctgcctacagtggccctaaggctggcgaaacttcacattcacagccc
actgcggtagcccgtgaagtgattgaacgtatcggtgacgcccaggtatctgtccctgaa
ggcttccaggtacacagcaagctgatgaacctgctacgcaagcgtcaaagcatgagccgc
caaggcggcattgactggggctttggtgagctgctggcctttggttcgctgctgatggaa
ggcgtaccggtgcacatgaccggtgaagatgtacgccgcgctacctttgcccagcgtcac
gccgtcatgcacgaccagcgtaacggttcagaatggaccccgctggactacctgaccccc
aaccaagccaagctgtcaattgttgactcgctgctaagcgaatacggcgctatggctttc
gaatacggctattcggtagagcgcagcgagggcctaaacatttgggaaggccagttcggc
gacttcgctaacggcgcccagaccgtaattgatgagtacgtctcttccgctgagcaaaag
tggggccagcactctggcctggttctgctgctgccgcacggtttggaaggccagggcccg
gaccactctagtgcccgcattgagcgctacctgcagctatgcgctcaggacaacatgcgc
gtggtgcagccttccaccccggctaaccacttccacaccctgcgtgaccaggcccgacgt
gaaccgcgccgacctttgatcctgatcagccccaagcaaatgctgcgtttgaaggccgcc
gtctcgccggtagaagacttcatcagcggcggcatgcaaactgtcattggtgaaaatgat
ccggaagttttagctgctgccgccgcgaacaaggtggatcgagtgctgctatgctcaggc
cgtatctactgggatctgctggcccaccgccagcacgcggaagataagcacactgccatc
gtgcgtctagagcagctctatcctctcgacgagccggccctgttggaggccctggcaccg
tttgcgggagccgagctggtttgggtccaggatgagccgcgcaaccagggcgcttggcct
tggttggctctgcacctgcctgactcgatcacggctggacgcttgccgcgagtagtggct
cgccctgaggctgccgccccggctgtgggtacttcagcagctcacgtagctcagcaaaag
ctgctcctagacgaggcttttgcccgctaa
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