Actinomadura graeca: AGRA3207_003487
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Entry
AGRA3207_003487 CDS
T07938
Name
(GenBank) lantibiotic dehydratase
KO
K20483
class I lanthipeptide synthase [EC:
3.13.2.4
]
Organism
agra
Actinomadura graeca
Pathway
agra02020
Two-component system
agra02024
Quorum sensing
Brite
KEGG Orthology (KO) [BR:
agra00001
]
09130 Environmental Information Processing
09132 Signal transduction
02020 Two-component system
AGRA3207_003487
09140 Cellular Processes
09145 Cellular community - prokaryotes
02024 Quorum sensing
AGRA3207_003487
Enzymes [BR:
agra01000
]
3. Hydrolases
3.13 Acting on carbon-sulfur bonds
3.13.2 Thioether and trialkylsulfonium hydrolases
3.13.2.4 lanthipeptide synthase
AGRA3207_003487
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Gene cluster
GFIT
Motif
Pfam:
Lant_dehydr_N
Lant_dehydr_C
Ifi-6-16
Motif
Other DBs
NCBI-ProteinID:
QXJ22483
UniProt:
A0ABX8QUQ9
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Position
complement(4003345..4006695)
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AA seq
1116 aa
AA seq
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MSQSPAEARPPLFEPWPAGMLRAPVLPAAFRLDPLPGAPGSPGVEDAARLLRAAVSDARF
MAALELASPDLVRGVRSVLDETENGTATGARAGGDAVRVALAVHRYARRAATRPTPFGLF
AGVTSVAFAGNTKVVWSDPAGHRVVARADNAVLARLTRVLELDGAVLWWLRVQTHQLVET
HGDRVVMPNPTNPDIDPGSDGRAVTSVRATPVVLAALGLARRPVAVHELAAALLARFARA
TDDAVLRLVRGLVAEQVLVTELRPRLGPGDRLAETHAVLRRVDREAAAAHAGGGDARVGD
PEVRARLDALDRVVRALPAAEPEEAVRLLRDVRGAANAHTNSAVHVDLRLGHRVQLPMDV
ASEGARAAEVLWRLAPPLLGTPALRGYHAEFVERYGLGRLVPVKELLDADRGLGAPAGYS
WPPGPRGGAGDGDPSQDAPGVRPPGIARLLTSLLWDAVRDGRREVVLDDALLDALCEGEH
DPDSAPPGFELYLHVVAADEAAVDRGDLRLVVSPNPGSHLDGSTFGRFGDVLPEAARGTV
AACVRDSARGEALPVVVRYEPRHARSGNIARDPGWTDTRLSVGVAALPDSGEEAGGPEEI
DLDDIAVGASLGGLYAVHAPSGRIVRPVFHNMLNVRTQAPNAVRLLCEIAFEHHQMWSPW
DWSAMGAAPYLPRVRYGRTVLWSASWSLEPLRPDAADPARFAAALADWRDRWAVPARILA
TSNDQRIRLDLRDGWDVELLRNELKRGMSLVAQEVPGGEDFADGWFSPGDAARGGGTGGD
AARDGEAGYVAEIVLPVRRREPDRRPRPTWAPLLTDRPRAVQPGAGWLYAKLYMAPERSD
VLVRDHLPELVGKAAALGGVDRWFFIRYTDPGFHIRLRLHGDAAVLNGPVLSLLHDTVSG
WERAGLAGRLVLDAYDPEYERYGGPEAMDAAERFFQADSETAMGLLRLAREHGLDPVDLA
AIGVTALVHAWGGPVAADDRAAVGTRWLHDPVAAWMSTTGPPHDVPPGFRRDRHRRAALI
DPAGGWPGLRELPGGPAVLDLLGHRDATLTAYRDVARNLVEPWTPESRIVGSLLHMHCNR
IIGAGGLEREAAAMSLARACALHHAERRRHTRKEDP
NT seq
3351 nt
NT seq
+upstream
nt +downstream
nt
gtgtcccagtcaccagccgaggcgaggccgccgctgttcgagccgtggcctgccggaatg
ctgcgcgcgccggtgctgcccgccgcgttccgcctcgatccccttcccggcgcccccggt
tcacccggcgtcgaggacgcggcgcggctgctccgcgcggcggtgtcggacgcccgtttc
atggcggcgctggaactggccagccccgacctggtccggggcgtgcgttccgtcctggac
gaaaccgagaacggaaccgcaaccggtgcgcgcgccggcggcgatgccgtgcgcgtcgcg
ctcgccgtgcaccgttacgcgcggcgcgccgcgacgaggccgacgccgttcgggctgttc
gcgggcgtgacgtcggtcgcgttcgcggggaacaccaaggtggtctggtcggatccggcc
ggccaccgcgtcgtggcccgcgccgacaacgccgtgctcgcgcggctgacccgcgtcctg
gaactggacggggcggtgctgtggtggctgcgcgtgcagacccaccagctcgtggagacg
cacggggaccgagtggtcatgcccaatcccaccaatccggacatcgacccgggcagcgat
ggcagggcggtcacctccgtgcgcgccacgcccgtcgtcctcgccgccctcgggctggca
cggcggcccgtggcggtgcacgagctcgccgcggcgctgctcgcccggttcgcgcgcgcg
acggacgacgccgtcctgcggctggtgcgcgggctggtcgccgagcaggtgctggtcacc
gagctgcggccgcggctcggccctggcgaccggctggcggagacgcacgcggtcctccgc
cgcgtcgaccgcgaggccgccgccgcgcacgcgggcggcggcgatgcccgggtgggggat
ccggaggtccgggcccgcttggacgcgctggaccgggtcgtccgcgccctcccggccgcc
gaaccggaggaggccgtgcggctgctgcgggacgtccgcggcgccgccaacgcccacacc
aactccgcggtccacgtggacctgcggctcgggcaccgggtgcagcttcccatggacgtc
gcctccgagggcgcgcgggccgccgaggtgctgtggcggctcgcccctcccctgctgggg
acgcccgcgctgcgcgggtaccacgccgagttcgtggagcggtacgggctcggccggctc
gtgccggtcaaggagctgctggacgccgaccgggggctcggcgcgcccgccgggtactcc
tggccgcccggcccgcgcggcggcgcgggcgacggggacccgtcgcaggacgcgccgggc
gtgcggccgcccggcatcgcgcggctcctcacgtccctgctctgggacgcggtccgcgac
ggccgccgggaggtggtcctggacgacgcgctcctggacgcgctgtgcgagggcgagcac
gacccggactccgcgccgcccggcttcgagctgtacctgcacgtcgtcgcggccgacgag
gcggccgtcgaccgcggtgacctccgtctcgtggtgtcaccgaaccccggctcccacctg
gacggatccacgttcggtcggttcggcgacgtgctccccgaggcggcgcgcggcaccgtc
gccgcctgcgtccgcgactccgcccgcggggaggcgctcccggtcgtcgtccgctacgag
ccgaggcacgcgcgcagcggcaacatcgcgcgcgaccccggctggacggacacgcggctg
tcggtcggggtcgccgcgctcccggactcgggcgaggaggcgggcggccctgaggagatc
gacctggacgacatcgccgtgggcgcgtccctcggcgggctctacgcggtgcacgccccg
agcggcaggatcgtccggccggtgttccacaacatgctcaacgtgcggacgcaggcgccg
aacgccgtgcggctgctgtgcgagatcgcgttcgagcaccaccagatgtggtcgccgtgg
gactggtcggcgatgggcgcggcgccgtacctgccgcgcgtccgttacggccggacggtg
ctgtggtcggcgagctggtcgctggagccgctgcgtccggacgcggcggacccggcgcgg
ttcgcggcggcgctcgcggactggcgggaccgctgggcagtccccgcccggatcctcgcg
acgagcaacgaccagcggatccgcctcgacctgcgggacggctgggacgtggaactgctc
cgcaacgagctgaagcggggcatgagcctggtggcgcaggaggtgccgggcggcgaggac
ttcgccgacggctggttctccccgggcgacgcggcgcgcggcgggggcaccggaggagac
gcggcgcgcgacggggaggccgggtacgtcgcggagatcgtcctgcccgtgcggcggcgg
gaacccgaccggcgcccgcgtcccacctgggcgccgctcctgacggaccgtccgcgcgcc
gtgcaacccggggccggctggctgtacgccaagctgtacatggcgccggagcgcagtgac
gtgctcgtccgcgaccacctgccggagctcgtgggcaaggccgcggcgctcggcggcgtg
gaccgctggttcttcatccgctacaccgaccccggattccacatccggctgcgcttgcat
ggagacgctgccgtattgaacggcccggtcctctcccttctgcacgacaccgtgtcgggc
tgggaacgcgcagggctcgccggacggctggtcctggacgcctacgaccccgagtacgag
cgctatggcggccccgaggcgatggacgccgcggaacgcttcttccaggccgactcggag
accgcgatgggcctgctgcggctggcccgggagcacgggctcgacccggtggacctcgcc
gcgatcggcgtcaccgccctcgtccacgcctggggcgggccggtcgcggcggacgaccgc
gcggccgtcgggacgcgctggctgcacgaccccgtcgcggcctggatgtcgaccaccggg
ccgccccatgacgtcccgccgggattccggcgggacaggcaccgcagggccgcgctcatc
gacccggccggcgggtggcctgggctccgtgagctgccaggcggccctgcggtgctggac
ctcctcggccaccgggacgcgacgctcacggcctaccgggacgtcgcccggaacctggtc
gaaccgtggacgccggagagccgtatcgtcggcagcctcctccacatgcactgcaaccgg
atcatcggcgcgggcggcctggagcgggaggccgccgcgatgtccctggcccgcgcgtgc
gcgctccatcacgcggagcgccgccgccacacccggaaggaagatccttga
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