Actinomadura graeca: AGRA3207_006045
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Entry
AGRA3207_006045 CDS
T07938
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
agra
Actinomadura graeca
Pathway
agra00020
Citrate cycle (TCA cycle)
agra00630
Glyoxylate and dicarboxylate metabolism
agra00785
Lipoic acid metabolism
agra01100
Metabolic pathways
agra01110
Biosynthesis of secondary metabolites
agra01120
Microbial metabolism in diverse environments
agra01200
Carbon metabolism
agra01210
2-Oxocarboxylic acid metabolism
Module
agra_M00009
Citrate cycle (TCA cycle, Krebs cycle)
agra_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
agra00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
AGRA3207_006045
00630 Glyoxylate and dicarboxylate metabolism
AGRA3207_006045
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AGRA3207_006045
Enzymes [BR:
agra01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
AGRA3207_006045
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
AGRA3207_006045
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
AGRA3207_006045
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
AGRA3207_006045
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GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QXJ24671
UniProt:
A0ABX8R293
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All DBs
Position
complement(6840204..6843911)
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AA seq
1235 aa
AA seq
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MSTESSQTSADPKITDFGANEWLVDELYQKYLEDPNSVDEAWWNFFADYQPDTRPSSVTT
PATEGAATKAANGTAAAPPTPKQPPVSPPKAPANTGSQPAPRAESRPAPPPVPAGAEEVR
LRGVAARTATNMEASLGVPTATSVRAVPAKLLIDNRIVINNHLKRGRGGKVSFTHLIGYA
IVKALAAMPEMNAAFTEVDGKPVLVRPEHVNFGLAIDLQKADGQRQLVVPSVKAAETLDF
RQFWAAYEEIVRKARGNKLTLEDFQGTTISLTNPGTIGTVHSVPRLMPGQGTIIGVGAME
YPAEFAGASSDTLSRMGISKVMTLTSTYDHRIIQGAQSGDFLRRIHELLLGEDGFYDEIF
EALRIPYEPVRWVKDISATHEDDVAKVARVHELIHAYRVRGHLMADTDPLEYKQRRHPDL
DILKHGLTLWDLEREFATGGFGGKPTMKLRDILGVLRMAYCRTVGIEYMHIQDPEERAWI
QERVEVPHDKPSREEQLHVLRRLNSAEAFETFLQTKFVGQKRFSLEGGESVIPLLDSVIS
AAAAASLDEVVIGMAHRGRLNVLANIVGKSYGQIFGEFEGNLDPRSAQGSGDVKYHLGAS
GDFIAGDGSKIHTELVANPSHLETVDPVLEGVVRAKQDLLDVGEAGFSVLPVLIHGDAAF
AGQGVVAETLNLSQLRGYRTGGTVHVVINNQVGFTTAPEYSRSSVYSTDVARMIQAPIFH
VNGDDPEACARVARLAFEYRQTFKKDVVIDMVCYRRRGHNESDNPSFTQPLMYDLIDAKR
SVRKLYTEALIGRGDITVEEAEQALRDYQEQLERAFTETREAVKKPLEPGSVVKPDVEES
IPIDHGKAGSAISQETVKRIIESQVSLPEGFEVHPRLKPILQRRAQMIEEDAIDWATGEL
LALGSLLIDGHPVRLVGQDTRRGTFGQRHSVLVDRKTGEEYTPLKQFGQGVSKFYVHDSL
LSEYAAMGFEYGYSMTRPDALVAWEAQFGDFANGAQSIMDEYISSGEQKWGQHSSVVLLL
PHGYEGQGPDHSSARIERYLQLCAQDNMTVVYPTTPANYFHLLRWQVLSGRGKPLIVFTP
KQLLRLKAATSTVAQITGGAFQPIIPESAPAVDPAGVRRVLLTTGKIYYEVVKARDAAGA
NDTAVIRVERLYPPPVDEIKAELAKYPGHTEVVWVQDEPANMGAWPFMALKLPHHIEGLR
LSRVSRPASSSPAVGSAKLHQAEQEALLARLFGEG
NT seq
3708 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgacagagtcgtcgcaaactagtgccgacccaaagatcacagacttcggtgccaac
gagtggctggtcgacgagctgtaccagaagtacctcgaggacccgaactcggttgacgag
gcctggtggaacttcttcgcggactaccagccggacacccggccgtcgtccgtgaccacc
ccggccaccgaaggagcggccacgaaggccgccaacggcaccgcggccgctccgccgaca
cccaagcagccaccggtctcgccgccgaaggcgccggcgaacaccggatcccagcccgcc
ccccgggccgagtccaggcccgcgccgcctccggtgcccgcgggcgccgaggaggtccgg
ctgcgcggcgtcgcggcgcggacggccaccaacatggaggccagcctcggcgtgccgacg
gcgacgagcgtgcgcgccgtcccggcgaagctgctgatcgacaaccgcatcgtcatcaac
aaccacctcaagcgcggccgcggggggaaggtctccttcacccacctgatcgggtatgcg
atcgtcaaggcgctcgcggcgatgccggagatgaacgccgcgttcaccgaggtggacggc
aagccggtgctggtcaggccggagcacgtcaacttcggcctcgcgatcgacctgcagaag
gcggacgggcagcggcagctggtggtgccgagcgtcaaggccgccgagacgctggacttc
cgccagttctgggcggcctacgaggagatcgtccgcaaggcgcgcggcaacaagctgacg
ctggaggacttccagggcaccacgatcagcctgacgaacccgggcacgatcggcaccgtc
cactcggtgccgcggctcatgccgggccagggcacgatcatcggcgtgggcgcgatggag
taccccgccgagttcgccggcgcgtccagcgacacgctgtcgcggatggggatcagcaag
gtcatgacgctgacctccacctacgaccaccggatcatccagggcgcgcagtccggcgac
ttcctgcgccgcatccacgagctgctgctcggcgaggacggcttctacgacgagatcttc
gaggccctgcgcatcccgtacgagccggtgcgctgggtcaaggacatctccgcgacgcac
gaggacgacgtcgccaaggtcgcccgggtgcacgagctgatccacgcctaccgggtccgg
ggccacctgatggccgacaccgacccgctggagtacaagcagcgccgccaccccgacctg
gacatcctcaagcacggcctcaccctgtgggacctggagcgcgagttcgcgacgggcggg
ttcggcggcaagccgaccatgaagctgcgcgacatcctcggcgtgctgcggatggcctac
tgccggacggtcggcatcgagtacatgcacatccaggaccccgaggagcgggcctggatc
caggagcgcgtcgaggtcccgcacgacaagccgtcgcgcgaggagcagctgcacgtcctg
cggcggctgaacagcgccgaggcgttcgagacgttcctgcagacgaagttcgtcgggcag
aagcggttctcgctggagggcggcgagtccgtcatcccgctgctggactcggtgatctcc
gcggcggcggccgcgagcctggacgaggtcgtcatcggcatggcgcaccgcggccggctg
aacgtcctcgccaacatcgtcggcaagtcctacgggcagatcttcggcgagttcgagggg
aacctcgacccgcgcagcgcgcagggctcgggggacgtcaagtaccacctgggcgcctcg
ggcgacttcatcgccggcgacggatccaagatccacaccgagctggtggcgaacccctcg
cacctggagacggtcgacccggtcctggagggcgtcgtccgcgccaagcaggacctcctg
gacgtcggcgaggccgggttcagtgtgctgcccgtcctgatccacggtgacgcggcgttc
gccgggcagggcgtggtcgccgagacgctgaacctgtcgcagctgcgcggctaccgcacc
ggcggcaccgtgcacgtcgtgatcaacaaccaggtgggcttcaccacggcccccgagtac
tcgcgctccagcgtctactcgacggacgtggcccggatgatccaggcgccgatcttccat
gtcaacggcgacgaccccgaggcgtgcgcgcgggtggcgcggctggcgttcgagtaccgg
cagacgttcaagaaggacgtcgtcatcgacatggtctgctaccggcggcggggccacaac
gagtccgacaacccctccttcacccagccgctgatgtacgacctgatcgacgccaagcgc
tcggtgcgcaagctgtacaccgaggcgctgatcgggcgcggcgacatcacggtggaggag
gccgagcaggcgctccgcgactaccaggagcagctggagcgggcgttcaccgagacccgc
gaggcggtgaagaagccgctcgaaccggggtcggtggtcaagccggacgtcgaggagagc
atcccgatcgaccacggcaaggccgggtcggcgatctcgcaggagaccgtcaagcggatc
atcgagtcccaggtcagcctgccggagggcttcgaggtccacccgcggctcaagccgatc
ctccagcgccgggcccagatgatcgaggaggacgcgatcgactgggcgaccggcgagctg
ctggcgctgggctccctgctgatcgacggccacccggtgcggctcgtcgggcaggacacc
cgccgcggcacgttcgggcagcggcactcggtgctggtcgaccgcaagacgggcgaggag
tacacgccgctcaagcagttcgggcagggcgtgtcgaagttctacgtgcacgactcgctg
ctcagcgagtacgcggcgatgggcttcgagtacggctactccatgacccgcccggacgcg
ctggtggcgtgggaggcgcagttcggcgacttcgcgaacggcgcccagtcgatcatggac
gagtacatctcgtcgggcgagcagaagtggggccagcactccagcgtcgtgctgctgctg
ccgcacgggtacgagggccagggccccgaccactcgtccgcgcggatcgagcgctacctg
cagctgtgcgcgcaggacaacatgaccgtggtctacccgaccaccccggcgaactacttc
cacctgctgcgctggcaggtgctgtcggggcgcggcaagccgctgatcgtgttcacgccg
aagcagctgctgcggctgaaggcggccacctcgacggtcgcgcagatcaccggcggcgcg
ttccagccgatcatccccgagagcgccccggcggtcgacccggcgggcgtgcggcgggtg
ctgctcaccaccggcaagatctactacgaggtggtcaaggcccgggacgccgcgggggcg
aacgacaccgccgtgatccgggtggagcggctgtacccgccgccggtggacgagatcaag
gcggagctggcgaagtacccgggccacacggaggtcgtgtgggtccaggacgagcccgcc
aacatgggcgcctggccgttcatggcgctgaagctgccgcaccacatcgagggcctgagg
ctgtcgcgggtgtcgcgcccggcgtcctcgtcccccgcggtggggtcggcgaagctgcat
caggccgagcaggaggccctcctggcccgcctgttcggcgaggggtaa
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