Aeromonas hydrophila subsp. hydrophila ATCC 7966: AHA_0432
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Entry
AHA_0432 CDS
T00424
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
aha
Aeromonas hydrophila subsp. hydrophila ATCC 7966
Pathway
aha00270
Cysteine and methionine metabolism
aha00450
Selenocompound metabolism
aha00670
One carbon pool by folate
aha01100
Metabolic pathways
aha01110
Biosynthesis of secondary metabolites
aha01230
Biosynthesis of amino acids
aha04980
Cobalamin transport and metabolism
aha04981
Folate transport and metabolism
Module
aha_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
aha00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
AHA_0432 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
AHA_0432 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
AHA_0432 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
AHA_0432 (metH)
04980 Cobalamin transport and metabolism
AHA_0432 (metH)
Enzymes [BR:
aha01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
AHA_0432 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
ABK39635
UniProt:
A0KFD9
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All DBs
Position
456603..460286
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AA seq
1227 aa
AA seq
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MSNKKSDVTNKLEACLKERILIIDGAMGTMIQGYKLGEADYRGARFADWHTDIKGNNDLL
VLTRPAVIREIHEQYCAAGADILETNTFNATRIAMADYEMEEFSAEINCEAARLARAVAD
EWTAKEPHKPRFVAGVLGPTNRTASISPDVNDPGKRNVTYDQLVAAYTESTHALIEGGAD
IILIETIFDTLNAKAAAFAVEGVFEALGYSLPVMISGTITDASGRTLSGQTTEAFYHSLR
HVKPVSFGLNCALGPDELRQYVEELSRISETHVSAHPNAGLPNAFGEYDLDAVEMAEHIR
EWAASGFLNLVGGCCGTTPTHIRAMADAVAGIKPRALPELPVACRLSGLEPLIITPESMF
VNVGERTNVTGSAKFKRLIKEGLYDEALDVAKQQVESGAQIIDINMDEGMLDAEAAMVRF
LNLIAGEPDIARVPVMIDSSKWEVLEAGLKCVQGKPVVNSISMKEGEEKFIQQARLLRRY
GAAVIVMAFDEVGQADTRARKFEICQRAYRILVDRVGFPPEDIIFDPNIFAVATGIDEHN
NYAVDFIDAVKDIKQNLPHAMISGGVSNVSFSFRGNEPVREAIHAVFLYHAIQNGMDMGI
VNAGQLAIYEDIPSDLKEKVEAVVLNLNPDATEALLAIAERYRGGGAQTEDPRDQAWRSW
PVGKRLEHALVKGITDFIEEDTEEARSKAEKPLHVIEGPLMDGMNVVGDLFGAGKMFLPQ
VVKSARVMKRAVAYLQPYIEAEKSGGSSNGKIVMATVKGDVHDIGKNIVGVVLQCNNYEI
VDLGVMVSCETILKTAREVNADIIGLSGLITPSLDEMVHVAKEMERQGFKLPLLIGGATT
SKAHTAVKIEQNYSEPVVYVSNASRAVGVAQSLLSPELKPAFVARIDKEYEIAREQHARK
QPRSKPVSLAHARANRHQLDWVGYQPPKPREPGVQTFEDVPVSVLRPYIDWTPFFLSWEL
AGKFPRILEDEVVGEEATRLYADANAMLDQLEQDRSVRCAGIIGLFPANAVGDSIEVYTD
ESRREVRKVLHHLRQQSEKQGFPNYCLADYVAPKESGKPDWIGAFAVTGGIGEEAIAKAY
KAEHDDYNAILIQAVCDRLAEAFAEYLHEQVRKVHWGYAPNEALSNEELIRENYRGIRPA
PGYPACPEHTEKGSIWELLGVEQAIGMKLTESYAMWPGAAVSGWYFSHPDSKYFAVAQIQ
QDQVEDYAQRKGMTLAEAERWLGPNLH
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgaacaaaaagtcggatgtgacaaacaaactggaagcctgtctcaaggagcggatc
ctgatcatcgatggcgccatgggcaccatgatccagggctacaagctcggtgaggccgat
tatcgcggcgcgcgtttcgccgactggcacaccgacatcaagggcaacaatgacctgctg
gtgctgacccgtcccgccgtgattcgcgagatccacgagcagtactgcgccgccggtgcc
gacatcctcgagaccaacaccttcaacgccacccgcatcgccatggccgactacgagatg
gaagagttctcggccgagatcaactgcgaggcggcccggctggcacgcgcggtggcagac
gagtggacggcgaaagagccccacaagccgcgcttcgtggccggggtcttgggcccgacc
aaccgcaccgcctccatctcgccggacgtgaacgatcccggcaagcgcaacgtcacctat
gaccagctggtggccgcctacaccgaatcgacccacgccctgatcgagggcggcgccgac
atcattctgatcgagaccatcttcgataccctcaacgccaaggccgccgccttcgcggtg
gaaggggtgttcgaggcgctgggctacagcctgccggtgatgatctcgggcaccatcacg
gatgcctccggccgtaccctctccggccagaccaccgaagccttctaccactcgctgcgc
catgtcaaaccggtctcgttcggtctcaactgcgcgctcgggccggatgagctgcgccag
tacgtggaggagttgtcgcgcatcagcgagacccatgtcagcgcccaccccaacgccggg
ttgcccaatgcgttcggcgagtacgacctcgatgccgtcgagatggccgagcatatccgc
gagtgggctgcgagcggctttctcaacctggtgggcggctgctgcggcaccaccccgacc
catattcgcgccatggcggacgccgtggcgggcatcaaaccgcgcgccctgcccgagctg
ccggtagcctgccggctgtcgggcctggagcccctcatcatcacccccgaatccatgttc
gtgaacgtgggggagcgcaccaacgtcaccggctcggccaagttcaagcggctgatcaag
gaggggctctacgacgaggccctcgacgtcgccaagcagcaggtggagagcggcgcccag
atcatcgacatcaacatggacgaggggatgctggacgccgaggcggccatggtgcgcttc
ttgaacctgattgccggcgaaccggacatcgcccgggtgccggtgatgatcgactcctcc
aagtgggaggtgctggaggccggcctcaagtgcgtgcagggcaagccggtagtcaactcc
atctccatgaaggagggggaggagaaattcatccagcaggccagattgctgcgccgctac
ggcgctgccgtcatcgtgatggcgttcgacgaggtgggccaggccgatacccgcgcccgc
aagttcgagatctgccagcgcgcctaccgcattctggtggaccgggtgggtttcccgccg
gaagacatcatcttcgaccccaacatcttcgcggtggcgaccggcatcgacgagcacaac
aactatgcagtggacttcatcgacgcggtgaaggacatcaagcagaacctgccccacgcc
atgatctccggtggcgtctccaacgtctccttctcgtttcgtggcaacgagccggtgcgc
gaggcgatccacgcggtgttcctctatcacgccatccagaacggcatggacatggggatc
gtcaacgccggtcagctggccatctacgaagacatcccgagcgatctgaaagagaaggtc
gaggcggtggtgctgaacctcaatccggacgccaccgaggcgctgttggccatcgccgag
cgctatcgcggtggcggagcccagaccgaggatccacgggatcaggcatggcgcagctgg
ccggtaggcaagcggctggagcatgcgctggtcaaggggatcaccgatttcatcgaggag
gataccgaggaggcccgcagcaaggctgagaagccgctgcacgtgatcgaggggccgctg
atggacggcatgaacgtggtgggcgatctgttcggcgccggcaagatgttcctgccccag
gtggtgaagtcggcgcgggtgatgaagcgggcggtcgcctacctgcagccctacatagag
gcggagaagtccggcggttccagcaacggcaaaatcgtgatggccaccgtgaagggggac
gtgcacgacatcggcaagaacatcgtcggggtggtgctgcagtgcaacaactacgagatc
gtcgatctcggggtcatggtctcttgcgagacgatcctcaagacggcgcgggaggtcaat
gccgacatcatcggcctgtcgggcctgatcaccccgtcgctggacgagatggtgcacgtg
gcgaaagagatggagcgccagggcttcaagttgccgctgctcatcggcggcgccaccacc
tccaaggcccacaccgcggtgaagatagagcagaactactccgaacccgtggtttatgtc
tccaacgcgtcgcgcgcggtgggggtggcccagagtctgctgagcccggagctcaagccc
gccttcgtggcccgcatcgacaaggagtacgagattgcccgcgagcagcacgcccgcaag
cagccgcgttccaagccggtcagtctggcccacgcccgtgccaaccgccatcagctggac
tgggtcggctatcagccacccaagccccgggagcccggtgtgcagaccttcgaggatgtg
ccggtctcggtgctgcgcccctacatcgactggacgccgttcttcctgagctgggagctg
gcgggcaagttcccccgcatcctggaagatgaggtggtgggggaggaggcaacgcgcctc
tacgccgacgccaacgccatgctggatcagctggagcaagatcggagcgtgcgctgcgcc
ggcatcataggcctgttccccgccaacgccgtgggcgacagcatcgaggtttataccgat
gagtcgcgccgcgaggtacgcaaggtgctgcaccacctgcgtcagcagagcgagaagcag
ggcttccccaactactgtctggcagactatgtggccccgaaggagagcggcaagcccgac
tggatcggtgccttcgcggtgaccggcggtatcggcgaggaggccatcgccaaggcttac
aaggcagagcacgacgactacaacgccatcctcattcaggcggtgtgcgatcgcctggcc
gaggccttcgccgagtacctgcacgaacaggtgcgcaaggtgcactggggttatgccccc
aacgaagcgctcagcaacgaggagctgatccgcgagaactatcgcggcatccgcccggcg
ccgggctacccggcctgcccggagcacaccgagaagggcagcatctgggaactgctgggg
gtggagcaggccatcggcatgaagctcaccgaatcctacgccatgtggccgggggcggcg
gtgtcgggctggtatttctcccaccccgacagcaagtacttcgcggtggcgcagatccag
caggatcaggtggaagattatgcccagcgcaaggggatgaccctggccgaagccgagcgc
tggctggggccgaacctgcattaa
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