KEGG   Actinomyces israelii: AIF0345_1916
Entry
AIF0345_1916      CDS       T06659                                 
Symbol
rocA
Name
(GenBank) 1-pyrroline-5-carboxylate dehydrogenase
  KO
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
Organism
air  Actinomyces israelii
Pathway
air00250  Alanine, aspartate and glutamate metabolism
air00330  Arginine and proline metabolism
air01100  Metabolic pathways
air01110  Biosynthesis of secondary metabolites
Module
air_M00970  Proline degradation, proline => glutamate
Brite
KEGG Orthology (KO) [BR:air00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    AIF0345_1916 (rocA)
   00330 Arginine and proline metabolism
    AIF0345_1916 (rocA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:air03000]
    AIF0345_1916 (rocA)
Enzymes [BR:air01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.88  L-glutamate gamma-semialdehyde dehydrogenase
     AIF0345_1916 (rocA)
  1.5  Acting on the CH-NH group of donors
   1.5.5  With a quinone or similar compound as acceptor
    1.5.5.2  proline dehydrogenase
     AIF0345_1916 (rocA)
Transcription factors [BR:air03000]
 Prokaryotic type
  Ribbon-helix-helix
   Other families
    AIF0345_1916 (rocA)
SSDB
Motif
Pfam: Aldedh Pro_dh
Other DBs
NCBI-ProteinID: WKR21983
LinkDB
Position
complement(2311809..2315375)
AA seq 1188 aa
MLTTVDHPLPGDAERRCPAELWELGEKAAARARRWADESASQPVPRTARLLARILSDPDG
LGFTTRFVDDVVRPIDLDVASHALARLAAGRTDFLPRSLAAAMGLGGRATRLAPRSVTTV
ARRVFREIVGDLVVDATDRGLGPALARLRTGGNRLNVNLLGEAVLGDREASRRLAEVSRL
VAREDVDYVSVKVSAVTGPHNPWGFEEVVAHGVEVLSPLYRLARDHGTFLNLDMEDYKDL
DLTIAVFTAILDQEDLTGYEAGIVLQAYLPDSLAAMERLQAWATARVDAGGSRIKVRVVK
GANLSMERVDAEIHGWELTTWPTKQATDTSYKRILSWAMTPERTRAIRLGVAGQNLFDIA
FAHELREARGVADDVEFEMLAGMATGLQEVVRHETGHLLLYVPVVDPGEFDVAISYLVRR
LEENAAPENFMSGVFDIASDPAVFDRERDRFLAALADLDPAAPAPAPNRSQDRLAEREAG
VPTATASAERIRRPFVSTPDSDPSLAANRRWARDIAAAVPASERGAAQVEAGAARMGTVA
RCDAVVRATAAAAAAWQGRDPDERAVVLNRVGDVLEARRHELIEVAASEAGKTIDQSDPE
VSEAIDFCRHYAEASLLLHDPEHMAGARFAPVDLTVVASPWNFPLAIPTGGVAAALAAGS
AVILKPAPPAKRCAAELVRAFHDAGLPEDLVVLAPLDDGEVSRHLVTHEQVDRVVLTGSY
DTARLFRSWRPDMRLLGETSGKNAIIVTPSADPDLAVRDVVASAFAHAGQKCSASSLLIL
VGSAGTSERIARQLVDATSSLRVRGPEHLDSQVGPVVVPDDEKALHGLTTLGAGEHWVLT
PRDLGDGLWRPGIRAGVVPGSEFHLTEYFAPVLGVMRVETLQEAIDAVNAVDYGLTSGLH
TLDADELAVWLDSVEAGNLYVNRGITGAIVRRQPFGGWKRSAIGSTTKAGGPSYLLGLGE
VVPAAGRNHEEAYEGHHDLVSTLDARVSALYDAVRTHLERRDMTELRRALVADAEAWRSQ
YGASRDVTGLVCERNVLRYRPTPVVVRAAGGTHPADLVRVVAAGVRAGAFVSLSVADRLP
AELASALAAANVEVDVEAPGVWSARLADLAASEALGLRVRVLGPREQTAACRWREASRLT
GGSPDVALYTGAVTTCPHSELLPFLREQAVAVTNHRFGTPLDLAAGLL
NT seq 3567 nt   +upstreamnt  +downstreamnt
atgttaaccaccgtcgatcaccccctgcccggcgacgctgagcgccgttgccccgcggag
ctgtgggagctcggtgagaaggcggccgcacgcgcgcgccgctgggccgacgagtcggcc
tcccagcccgttccccgcacagcgcggcttctggcgcgcatcctgtcggatccggacggt
ctggggttcacaacccgcttcgtcgatgacgtcgtgcgacccatcgacctcgacgtcgcc
agtcatgctctggcgcggctggccgctgggcgcaccgacttcctgccgcgctccctggcc
gcggccatgggcctgggaggccgggcgacccgcctggcgccccgctcggtgaccaccgtg
gcccggcgcgtcttccgcgagatcgtcggcgacctcgtcgtggacgccaccgaccggggg
ctgggccccgccctggcccggctgcgcaccggcggcaaccgtctcaatgtcaaccttctg
ggcgaggccgtcctgggggacagggaggcctcccgccggctggcggaggtctcccgcctc
gtggcccgcgaggacgtcgactacgtgtcggtcaaggtctcggccgtcaccggcccgcac
aacccctggggcttcgaggaggtcgtcgcccacggcgtggaggtgctctccccgctgtac
cgcctggcccgcgaccacggcaccttcctcaacctcgacatggaggactacaaggacctc
gacctgaccatcgcggtgttcaccgccatcctcgaccaggaggacctgaccggctacgag
gccggcatcgtgctgcaggcctacctgccggactccctggccgccatggagcgtctccag
gcctgggcgaccgcccgcgtggacgccggcgggtcgcgcatcaaggtgcgcgtggtcaag
ggcgccaacctgtccatggagcgggtggacgccgagatccacggctgggagctgaccacc
tggccgaccaagcaagccacggacacgagctacaagcgcatcctctcctgggccatgacc
cccgagcgcacccgcgccatccgtctgggggtggcggggcagaacctgttcgacatcgcc
ttcgcccacgagctgcgggaggcccggggcgtggcggacgacgtcgagttcgagatgctc
gcgggcatggccaccggcctgcaggaggtcgtgcgccatgagacgggccaccttctgctg
tacgtgcccgtggtcgacccgggcgagttcgacgtcgccatctcctacctggtgcgccgc
ctggaggagaacgcggcgccggagaacttcatgtccggggtcttcgacatcgcctccgac
ccggccgtcttcgaccgcgagcgcgaccggttcctggccgctctggccgacctcgacccc
gccgcgcccgcgccggcccccaaccgctcccaggaccggctcgccgagcgcgaggcgggc
gtcccgaccgccaccgcctcggccgagcgcattcggcgtcctttcgtctcgacaccggac
tcggacccctcgctggccgccaaccgccggtgggcccgcgacatcgccgccgccgtgccg
gcctccgagaggggcgccgcccaggtcgaggcgggcgccgcccgcatgggaaccgtcgcg
aggtgcgacgcggtcgtgagggcgaccgcggccgccgccgcggcctggcaggggcgcgac
cccgacgagcgcgccgtcgtcctgaaccgggtcggggacgtcctggaggcccgccgccac
gagctcatcgaggtcgccgcctccgaggcgggcaagaccatcgaccagtccgatcccgag
gtcagcgaggccatcgacttctgccgccactacgccgaggcctccctgctgctgcacgac
ccggagcacatggccggcgcccgcttcgcgccggtggacctgaccgtggtcgcctcgccg
tggaacttccccctggcgatccccaccgggggagtggcggccgccctggccgcgggcagc
gccgtcatcctcaagccggctccgcccgccaagcgctgcgccgccgagctcgtgcgcgcc
ttccacgacgccggccttccggaggacctcgtggtcctcgccccgctggacgacggcgag
gtctcgcgccacctggtgacccacgagcaggtggaccgcgtggtgctcaccggctcctac
gacaccgcgcggctcttccgctcctggaggccggacatgcgcctgctgggggagaccagc
ggcaagaacgccattattgtcacgccttcggccgatccggatctcgccgtgcgcgacgtg
gtggcctccgccttcgcccacgccggacagaagtgctcggcgagctccctgctcatcctg
gtcggctcggccgggacctcggagcgcatcgcccgccagctggtggacgcgacctcctcc
ctgcgggtgcgcggccccgagcacctggactcccaggtcggccccgtcgtcgtccccgac
gacgagaaggcgctgcacggcctgacgacgctgggagccggcgagcactgggtgctgact
ccgcgggatctgggcgacggcctgtggcgccccggcatccgcgccggtgtcgtccccggc
agtgagttccacctgaccgagtacttcgccccggtgctgggcgtcatgcgggtggagact
ctccaggaggccatcgacgccgtcaacgccgtcgactacggcctgacctcggggctgcac
acgcttgacgccgacgagctcgcggtctggctggactcggtcgaggccgggaacctctac
gtcaaccgcggcatcaccggcgcgatcgtgcgacgccagcccttcgggggctggaagcgc
tcggcgatcgggtcgacgaccaaggccggcgggccgtcctacctgctcgggctgggcgag
gtcgttccggccgccggccggaaccacgaggaggcctacgagggccaccacgacctggtg
tccaccctggacgcgcgcgtgtccgccctctacgacgccgtgcgcacccacctggagcgt
cgcgacatgaccgagctgcgccgcgcgctcgtggccgacgccgaggcgtggcggtcccag
tacggcgcgagccgggacgtcacgggcctggtctgcgagcgcaacgtgctgcgctaccgg
cccacgcccgtcgtcgtgcgggccgcgggcggcacccaccccgccgacctggtgcgcgtc
gtggcggccggcgtgcgtgcgggcgccttcgtgagcctgtccgtggcggacaggctcccg
gccgagctggcgagcgcgctggccgccgccaatgtcgaggtggatgtcgaggcgccgggc
gtgtggagcgcgcgcctggcggacctggcggcctccgaggcgctcgggctgcgcgtgcgc
gtgctggggccgcgtgagcagaccgctgcctgccggtggcgggaggcgagtcgcctcacc
ggcggcagccccgacgtcgccctgtacacgggggccgtgacgacctgcccgcactccgag
ctgctgcccttcctgcgcgagcaggcggtcgcggtcaccaaccaccgcttcggcacgccg
ctcgacctggccgccgggctgctctga

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