Amycolatopsis japonica: AJAP_05305
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Entry
AJAP_05305 CDS
T03225
Symbol
kgd
Name
(GenBank) Multifunctional 2-oxoglutarate metabolism enzyme
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
aja
Amycolatopsis japonica
Pathway
aja00020
Citrate cycle (TCA cycle)
aja00630
Glyoxylate and dicarboxylate metabolism
aja00785
Lipoic acid metabolism
aja01100
Metabolic pathways
aja01110
Biosynthesis of secondary metabolites
aja01120
Microbial metabolism in diverse environments
aja01200
Carbon metabolism
aja01210
2-Oxocarboxylic acid metabolism
Module
aja_M00009
Citrate cycle (TCA cycle, Krebs cycle)
aja_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
aja00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
AJAP_05305 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
AJAP_05305 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AJAP_05305 (kgd)
Enzymes [BR:
aja01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
AJAP_05305 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
AJAP_05305 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
AJAP_05305 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
AJAP_05305 (kgd)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AIG73981
UniProt:
A0A075UNJ5
LinkDB
All DBs
Position
complement(1051553..1055275)
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AA seq
1240 aa
AA seq
DB search
MSSSSPASQFGPNEWVVEEMYDQFLADPSSVDAAWHDFFADFKPTQDAQTKADDARQNSG
DPGNEGPGANGQAAATPSAQTVRNAESTAKQTAPRSAPAKAAAPKAAAPAAAPKAAEKAP
AKPAEKDAEAESKQLRGAAAAIAKNMDASLSVPTATSVRAVPAKLMADNRIVINNHLKRT
RGGKISFTHLIGYAMVRALKNFPNMNRHYQLIDGKPFAITPEHVNFGLAIDMKGKEGSRT
LVVASIKATENMTFMQFWQAYEEIVKKARNGKLTADDFAGTTISLTNPGGIGTNHSVPRL
QAGQGAIIGVGAMQYPAHFEGTSEKALVDLGVSKIMTLTSTYDHRIIQGAESGEFLKRIH
ELLLGEDGFYDDVFTSLRLPYEPIRWVADIPDGPVDKTARVIELIDAFRMRGHLMADTDP
LNYRQRSHADLDVLSHGLTLWDLDREFPVGGFAGQERMKLRDILGVLRNSYCRTVGIEYT
HILDPEERRWIQDRVEIPHEKPDPAVQKYVLSKLNAAEAFETFLQTKYVGQKRFSLEGGE
TAIPLLDTLLDKAAEHELDEVVIGMPHRGRLNVLANIVGKPIAQIFQEFEGNLDPGQAHG
SGDVKYHLGAEGKYFRMFGDGETKVSLTANPSHLETVDPVLEGIVRAKQDILDKGGEGFT
VLPVLMHGDAAFAGQGVVAETLNLALLRGYRTGGTVHVIVNNQVGFTTAPEHSRSSQYAT
DVAKMIGSPIFHVNGDDPEAAHWVAKLAVDYRQAFHKDVVIDLICYRRRGHNEGDDPSMT
QPAMYDIIDTKRSVRKTYTESLIGRGDISVEEAEAALRDFSSQLEHVFNEVRELEKHPAK
ASPSVEEEQQVPAKVPTATTTEVIEHIGDAFLNVPEGFTPHPRVKPVMERRHKMSREGGI
DWAFGELLAFGSLAMEGRLVRLSGQDSRRGTFTQRHSVLIDRKTGQEYSPLASLAENQGR
VMIYDSALSEYAAVGFEYGYSVANSEALVMWEAQFGDFVNGAQTVIDEYISSGEAKWGQL
SDVVLLLPHGHEGQGPDHTSGRIERFLSLCAEGSMTVAVPSTPANYFHLLRRHALDGVNR
PLITFTPKSMLRNKAATSAVEDFTGQTKFMSVIDDAVVDPSKVRKVLLTSGKLYWELVAE
RTKREANDVAIVRVEQYYPLPKKKLLAALERYNGAPAVWVQEEPENQGAWPFFGLNLPRK
LPEVFSNLDVVSRRPMAAPSAGSSKVHEVEQKALIARAFD
NT seq
3723 nt
NT seq
+upstream
nt +downstream
nt
gtgtccagcagcagccctgcgtcacaattcggccccaacgagtgggtcgtcgaggaaatg
tacgaccagttccttgccgaccccagctcagtcgatgccgcctggcacgacttcttcgcg
gacttcaagccaacgcaggacgcgcagacgaaggccgacgacgcacgtcagaactccgga
gaccccggcaacgagggtcccggcgccaacggccaggccgccgccacgccgtcggcgcag
acagtccgcaacgccgagtccaccgcgaagcagaccgcgccgaggagcgcccccgcgaag
gccgccgcacccaaggcggcggcccccgcggccgcgcccaaggcggcggagaaggccccc
gccaagccggccgagaaggacgccgaggcggagtcgaagcagctccgcggcgccgcggcg
gcgatcgcgaagaacatggacgcctcgctgtccgtgccgacggccacgagtgtgcgcgcc
gtcccggcgaagctgatggccgacaaccgcatcgtcatcaacaaccacctcaagcgcacg
cgcggcggcaagatctccttcacgcacctcatcggctacgcgatggtccgggcgctgaag
aacttcccgaacatgaaccggcactaccagctgatcgacgggaagccgttcgcgatcaca
ccggagcacgtgaacttcggtctcgcgatcgacatgaagggcaaggaaggctcccgcacg
ctcgtcgtggcctccatcaaggccaccgagaacatgaccttcatgcagttctggcaggcc
tacgaggagatcgtcaagaaggctcgcaacggcaagctgaccgccgacgacttcgccggc
accacgatctcgctgaccaaccccggcggcatcggcaccaaccactcggtgccgcgtctg
caggcgggccagggcgcgatcatcggcgtcggcgccatgcagtacccggcgcatttcgag
ggcaccagcgagaaggcgctggtcgacctcggcgtctcgaagatcatgacgctgacctcg
acgtatgaccaccgcatcatccagggcgcggagtcgggcgagttcctcaagcgcatccac
gagctgctgctcggcgaggacggcttctacgacgacgtcttcaccagcctgcgcctgccg
tacgagccgatccgctgggtcgccgacatcccggacggcccggtcgacaagaccgcgcgc
gtcatcgagctgatcgacgccttccgcatgcgcggtcacctgatggccgacaccgacccg
ctcaactaccggcagcgcagccacgccgacctcgacgtcctctcccatggcctgaccctg
tgggacctggaccgcgagttcccggtcggcggcttcgccggccaggagcggatgaagctg
cgcgacatcctcggcgtgctgcgcaactcctactgccgcaccgtcggcatcgagtacacg
cacatcctcgaccccgaggagcgccgctggatccaggaccgcgtcgagatcccgcacgag
aagccggaccccgcggtccagaagtacgtgctctcgaagctcaacgccgccgaggcgttc
gagaccttcctgcagaccaagtacgtcggccagaagcgattctccctcgaaggcggcgag
acggcgatcccgctgctggacacgctgctggacaaggccgccgagcacgaactcgacgag
gtcgtcatcggcatgccgcaccgcggccgcctgaacgtgctcgcgaacatcgtcggcaag
ccgatcgcgcagatcttccaggagttcgagggcaacctcgacccgggtcaggcgcacggt
tccggtgacgtgaagtaccacctcggcgccgagggcaaatacttccgcatgttcggcgac
ggcgagaccaaggtgtcgctgaccgcgaacccgtcgcacctggagaccgtcgacccggtc
ctcgagggcatcgtccgcgcgaagcaggacatcctcgacaagggtggcgagggcttcacc
gtcctcccggtcctgatgcacggcgacgcggccttcgcgggccagggtgtcgtggccgag
accctgaacctggcgctgctgcgcggctaccgcaccggcggcaccgtgcacgtcatcgtc
aacaaccaggtcggcttcaccaccgcgcccgagcactcgcgttcgagccagtacgccacc
gacgtcgcgaagatgatcggctcgccgatcttccacgtgaacggtgacgaccccgaggcc
gcgcactgggtggccaagctggccgtcgactaccgccaggcgttccacaaggacgtcgtg
atcgacctgatctgctaccgccgccgcggccacaacgagggcgacgacccctcgatgacg
cagccggcgatgtacgacatcatcgacacgaagcgttcggtccggaagacctacaccgaa
tcgctcatcggccgcggcgacatctccgtcgaagaggccgaagccgcgttacgcgacttc
tccagccagctggagcacgtgttcaacgaggtccgcgagctggagaagcacccggcgaag
gccagcccctcggtcgaggaggagcagcaggtcccggccaaggtgcccaccgcgacgacc
accgaggtcatcgagcacatcggcgacgcgttcctcaacgtgcccgagggcttcaccccg
cacccgcgggtcaagccggtcatggagcgccgccacaagatgtcccgcgaaggtggcatc
gactgggccttcggcgagctgctcgccttcggttcgctggccatggaaggccgcctcgtg
cggctgtccggccaggactcccgccgcggcaccttcacccagcgccactcggtgctgatc
gaccgcaagaccggccaggagtactcgccgctggccagcctcgccgagaaccagggccgc
gtgatgatctacgactcggcgctgtccgagtacgcggcggtcggcttcgaatacggctac
tccgtggccaactccgaagcgctggtcatgtgggaagcgcagttcggtgacttcgtcaac
ggcgcgcagaccgtcatcgacgagtacatctcctccggcgaggccaagtggggccagctc
tccgacgtcgtgctgctgctgccgcacggccacgaaggccagggcccggaccacacctcc
ggccgcatcgagcgcttcctctcgctgtgcgcggagggctcgatgaccgtcgcggtgccg
tcgaccccggcgaactacttccacctgctccgccgccacgccctcgacggggtgaaccgg
ccgctgatcaccttcaccccgaagtcgatgctgcgcaacaaggcggcgacctcggcggtc
gaggacttcaccgggcagacgaagttcatgtcggtcatcgacgacgccgtcgtcgacccg
tcgaaggtccgcaaggtcctgctgacgtcgggcaagctgtactgggagctggtggccgag
cgcacgaagcgcgaggcgaacgacgtcgcgatcgtgcgcgtcgagcagtactacccgctg
ccgaagaagaagctgctggcggcgctggagcgctacaacggcgctcccgcggtctgggtc
caggaggagccggagaaccagggcgcgtggccgttcttcggcctgaacctgccccggaag
ctcccggaggtgttctccaacctggatgtcgtgtcgcgtcgtccgatggccgccccgtcg
gccggttcgtccaaggtgcacgaggtcgagcagaaggcgctgatcgcgcgggcgttcgac
tga
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