Amycolatopsis japonica: AJAP_10465
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Entry
AJAP_10465 CDS
T03225
Symbol
aceE
Name
(GenBank) Pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
aja
Amycolatopsis japonica
Pathway
aja00010
Glycolysis / Gluconeogenesis
aja00020
Citrate cycle (TCA cycle)
aja00620
Pyruvate metabolism
aja00785
Lipoic acid metabolism
aja01100
Metabolic pathways
aja01110
Biosynthesis of secondary metabolites
aja01120
Microbial metabolism in diverse environments
aja01200
Carbon metabolism
aja01210
2-Oxocarboxylic acid metabolism
Module
aja_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
aja00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
AJAP_10465 (aceE)
00020 Citrate cycle (TCA cycle)
AJAP_10465 (aceE)
00620 Pyruvate metabolism
AJAP_10465 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AJAP_10465 (aceE)
Enzymes [BR:
aja01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
AJAP_10465 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AIG74988
UniProt:
A0A075UPQ2
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All DBs
Position
complement(2120703..2123498)
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AA seq
931 aa
AA seq
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MAPQNDGASGKETPARVRVIRDGLAAHLPDIDPEETAEWLDSFDEALARGGQQRARYLML
RILERARERHVGVPALTSTDYVNTIPTENEPWFPGDEEIERRYRAYIRWNAAIMVHRAQR
PGVGVGGHISTYGSSAALYEVGFNHFFRGKDHSGGGDQIFIQGHASPGIYARAFLEGRLT
ENQLDGFRQEFSHAGEGGGLPSYPHPRLMPEFWENPTVSMGLGPMNAIYQARFNRYLRDR
GIKDTSDQHVWAFLGDGEMDEPESRGLIHVAASEGLDNLTFVINCNLQRLDGPVRGNGKI
IQELESYFRGAGWNVIKVIWGREWDSLLHADRDGALVNLMNTTPDGDFQTYKANDGAFVR
EHFFGRDPRTKELVKDLTDADVWNLKRGGHDYRKVYAAYKSSLEHHGQPTVILAHTIKGY
GLGPSFEGRNATHQMKKLTLDDLKLFRDAQRIPISDEELERDPKLPPYYHPGKESAEIEY
MIGRRRALGGFLPERRPKASKALVLPGDKVYEGIRKGSGKQEVATTMAFVRLVRELAKDS
EIGKRIVPIIPDEARTFGLDSMFPTAKIYNPHGQTYTSVDASLMLAYKESEKGVILHEGI
NEAGSTASFTAVGTSYATHGEPMIPIYIFYSMFGFQRTGDGLYAAADQMARGFVLGATAG
RTTLTGEGLQHADGHSLLLAATNPAVVAYDAAWSFEIAHIVRDGLRRMYGETGPDGNGEN
IFYYMTIYNEPYQQPAEPENLDVDGLLKGLYKYADAPSGDGPEAQILVSGVTMPDALRAQ
QMLAEEWGVRAAVWSATSWTELRREAVEVDHDNLLHPGDSPRVPYITQKLSGANGPVVAV
SDWMRAVPDLIRPWVPTDMLTLGTDGFGFSDTRPAARRKFLVDAQSIVVGTLSALAKRGE
IDRSKAAEAARKYRLDDVAAAGPQLSDSGSA
NT seq
2796 nt
NT seq
+upstream
nt +downstream
nt
ttggccccgcagaacgacggcgcctccggcaaggagaccccggcacgcgtccgcgtcatc
cgtgacggattggcggcgcacctgcccgacatcgacccggaggagaccgccgaatggctg
gactccttcgacgaggcgctggccaggggtggtcagcagcgcgcccggtacctgatgctg
cgcatcctcgagcgggccagggagcgccacgtcggcgtcccggcgctgacgtcgacggac
tacgtcaacaccatccccaccgagaacgaaccctggttccccggtgacgaggagatcgag
cgccggtaccgcgcctacatccgatggaacgccgcgatcatggtgcaccgcgcgcagcgt
cccggcgtcggcgtcggtgggcacatctcgacctacggctcgtccgcggcgctgtacgaa
gtgggcttcaaccacttcttccgcggcaaggaccactcgggcggcggcgaccagatcttc
atccagggccacgcctcccccggcatctacgcccgcgcgttcctcgagggcaggctgacc
gagaaccagctggacggcttccgccaggagttctcgcacgccggcgagggcggcggcctg
ccgtcgtacccgcacccgcggctgatgccggagttctgggagaacccgaccgtgtccatg
ggcctcggcccgatgaacgcgatctaccaggcgcgattcaaccgctacctgcgcgaccgc
ggcatcaaggacaccagcgaccagcacgtctgggcgttcctcggcgacggcgagatggac
gagccggaatcgcgcggcctcatccacgtggccgcgagcgagggcctcgacaacctgacc
ttcgtgatcaactgcaacctgcagcggctcgacggcccggtgcgcggcaacggcaagatc
atccaggagctggagtcgtacttccgcggcgccggctggaacgtcatcaaggtcatctgg
ggccgcgagtgggactcgctgctgcacgcggaccgtgacggcgccctggtcaacctgatg
aacaccacgccggacggcgatttccagacctacaaggccaacgacggcgcgttcgtccgc
gagcacttcttcggccgcgacccgcggaccaaggaactcgtcaaggacctcaccgacgcc
gacgtctggaacctcaagcgcggcgggcacgactaccgcaaggtctacgcggcctacaag
tcgtcgctggagcaccacggccagccgacggtgatcctggcccacaccatcaagggttac
ggcctcgggccgtccttcgagggccgcaacgccacgcaccagatgaagaagctcaccctc
gacgacctcaagctgttccgggacgcccaacgcatcccgatcagcgacgaggagctcgag
cgcgacccgaagctgccgccgtactaccaccctggcaaggaatcggccgagatcgagtac
atgatcggccgccgtcgcgcgctcggcgggttcctgccggaacgccgcccgaaggcctcg
aaggccctcgtgctgcccggcgacaaggtctacgaaggcatccgcaagggctcgggcaag
caggaggtcgccaccacgatggcgttcgtccggctcgtccgcgagctggcgaaggactcc
gagatcggcaagcggatcgtcccgatcatcccggacgaggcgcgcaccttcggtctcgac
tcgatgttcccgacggccaagatctacaacccgcacggccagacgtacacgtcggtcgac
gcgagcctgatgctggcctacaaggagtccgaaaagggcgtcatcctgcacgagggcatc
aacgaggcgggctcgaccgcgtcgttcaccgccgtcggcacctcgtacgccacgcacggc
gagccgatgatcccgatctacatcttctactcgatgttcgggttccagcggaccggtgac
ggcctctacgcggcggccgaccagatggcccgcgggttcgtgctcggcgccaccgccggc
cgcaccacgctgaccggtgagggcctccagcacgccgacgggcactcgctgctgctggcg
gcgaccaacccggccgtcgtggcctacgacgcggcgtggtcgttcgagatcgcccacatc
gtgcgggacggtcttcgccggatgtacggcgagaccgggccggacggcaacggcgagaac
atcttctactacatgacgatctacaacgagccctaccagcagcccgccgagcccgagaac
ctcgacgtcgacggcctgctcaagggtctctacaagtacgcggacgccccgtcgggcgac
ggcccggaggcgcagatcctggtctccggcgtcaccatgccggacgcgctgcgggcgcag
cagatgctggccgaggagtggggcgtacgcgcggccgtgtggtcggcgacgtcgtggacc
gagctgcggcgcgaggccgtcgaggtcgaccacgacaacctgctccacccgggcgactcc
ccgcgtgtgccgtacatcacgcagaagctgtccggcgcgaacgggccggtcgtcgcggtg
tcggactggatgcgggccgtgccggatctcatccgcccctgggtgccgaccgacatgctg
acgctgggcaccgacgggttcgggttctccgacacccgtcccgccgcccggcggaagttc
ctggtcgacgcccagtcgatcgtggtcggcacgctgagcgcgctggccaagcgcggcgag
atcgaccggtcgaaggcggcggaggcggcgcgcaagtaccgtctcgacgacgtcgccgcc
gcgggtccgcagttgtcggactccggtagcgcctga
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