Apostichopus japonicus (Japanese sea cucumber): 139968030
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Entry
139968030 CDS
T10891
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2-like
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
ajj Apostichopus japonicus (Japanese sea cucumber)
Pathway
ajj01100
Metabolic pathways
Module
ajj_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
Enzymes [BR:
ajj01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
139968030
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
139968030
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
Polysacc_synt_2
NAD_binding_10
GDP_Man_Dehyd
RmlD_sub_bind
KR
adh_short
Motif
Other DBs
NCBI-GeneID:
139968030
NCBI-ProteinID:
XP_071828423
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Position
5:complement(21580996..21592107)
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AA seq
378 aa
AA seq
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MTNQEGVTILVTGGAGFLGQHIVKELMEQEVFPVKEIRSFDIQPFKWHHGLHPSKNSHKL
NHIEGSICDPAAVTKACENVDAVIHNCGCVAFGAYPNRKSIRAVNVDGTENAVNACIEQN
VECLVYTSSIEVANDLKKPSVNASETSVTVPAINPVLCVYSQSKYDAEIMVLRANNKALK
NGKKLRTCALRPCGMYGEGEHILTTNLGYFINAGVALRIGEPSGKIQYAYAGNIAYSYVL
AVKSLLRPDEKTDISGEAFFLGDDTPLYSIGEMVAQFAKALVAETGTATPPYWLMYTIAF
FLTVMCWLVSNIKNWEMPFHTNAVRFMFGEYHYSWEKLQRVLGYKPRYTYKEAFDRSITY
YEHYFGLNNKSNQNKKQK
NT seq
1137 nt
NT seq
+upstream
nt +downstream
nt
atgactaatcaggaaggtgtaaccatccttgtgacgggaggagccggatttcttggtcaa
catatcgtcaaagagttgatggaacaagaggtatttcctgtgaaggaaatacgatcattt
gatatccagcctttcaagtggcaccacggtctacatccatcgaagaattctcataaactt
aaccacatcgagggtagtatctgtgatcccgcagctgtaactaaagcctgcgaaaatgtg
gacgccgtcatccataattgcggctgtgttgcgtttggtgcatatcctaacagaaagtca
atacgcgctgttaacgtagacggaacagaaaatgcggtgaacgcctgtattgaacagaac
gttgaatgtctagtctacacgagttctattgaagtagcgaacgatcttaaaaagcctagt
gttaacgcctccgagacatcggttacagtccccgctatcaacccagtcttgtgtgtttat
tctcagtccaagtacgatgccgagataatggttctgagagccaacaataaagcactaaaa
aacggtaaaaaattgaggacgtgcgctctgagaccatgtggcatgtacggggagggggaa
catattctaacaacaaatttggggtatttcataaatgctggggttgcactccgcataggt
gaaccgagcgggaagattcaatatgcatacgctgggaatatcgcatactcatacgtattg
gcagtcaaatcactcttacgtcccgacgagaagacagatattagtggagaagcgttcttc
ttaggcgatgacacccctctttatagtattggggaaatggtcgcacagtttgcaaaggct
ttagtggccgaaacaggtacggcaacaccaccatattggctcatgtatacgattgctttc
ttccttaccgtcatgtgttggctagtatccaatataaaaaattgggagatgccatttcac
accaatgctgtgcgattcatgttcggtgaatatcactacagttgggagaaacttcaacgt
gtgttaggctataagcctaggtatacatacaaagaagcgtttgatcgtagtatcacatat
tacgaacattattttggtctcaataacaaatcaaaccaaaataaaaaacaaaagtag
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