Acinonyx jubatus (cheetah): 106968223 Help Entry 106968223         CDS       T04657                                  Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism aju  Acinonyx jubatus (cheetah) Pathway aju00230   Purine metabolism aju01100   Metabolic pathways aju01522   Endocrine resistance aju04015   Rap1 signaling pathway aju04020   Calcium signaling pathway aju04022   cGMP-PKG signaling pathway aju04024   cAMP signaling pathway aju04062   Chemokine signaling pathway aju04072   Phospholipase D signaling pathway aju04081   Hormone signaling aju04082   Neuroactive ligand signaling aju04114   Oocyte meiosis aju04211   Longevity regulating pathway aju04213   Longevity regulating pathway - multiple species aju04261   Adrenergic signaling in cardiomyocytes aju04270   Vascular smooth muscle contraction aju04371   Apelin signaling pathway aju04540   Gap junction aju04611   Platelet activation aju04713   Circadian entrainment aju04714   Thermogenesis aju04720   Long-term potentiation aju04723   Retrograde endocannabinoid signaling aju04724   Glutamatergic synapse aju04725   Cholinergic synapse aju04727   GABAergic synapse aju04750   Inflammatory mediator regulation of TRP channels aju04911   Insulin secretion aju04912   GnRH signaling pathway aju04913   Ovarian steroidogenesis aju04914   Progesterone-mediated oocyte maturation aju04915   Estrogen signaling pathway aju04916   Melanogenesis aju04918   Thyroid hormone synthesis aju04921   Oxytocin signaling pathway aju04923   Regulation of lipolysis in adipocytes aju04925   Aldosterone synthesis and secretion aju04926   Relaxin signaling pathway aju04927   Cortisol synthesis and secretion aju04928   Parathyroid hormone synthesis, secretion and action aju04934   Cushing syndrome aju04935   Growth hormone synthesis, secretion and action aju04970   Salivary secretion aju04971   Gastric acid secretion aju04972   Pancreatic secretion aju04976   Bile secretion aju05032   Morphine addiction aju05142   Chagas disease aju05146   Amoebiasis aju05163   Human cytomegalovirus infection aju05166   Human T-cell leukemia virus 1 infection aju05200   Pathways in cancer aju05207   Chemical carcinogenesis - receptor activation aju05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:aju00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     106968223  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     106968223    04371 Apelin signaling pathway     106968223    04020 Calcium signaling pathway     106968223    04072 Phospholipase D signaling pathway     106968223    04024 cAMP signaling pathway     106968223    04022 cGMP-PKG signaling pathway     106968223   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     106968223    04081 Hormone signaling     106968223  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     106968223   09144 Cellular community - eukaryotes    04540 Gap junction     106968223  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     106968223    04062 Chemokine signaling pathway     106968223   09152 Endocrine system    04911 Insulin secretion     106968223    04923 Regulation of lipolysis in adipocytes     106968223    04912 GnRH signaling pathway     106968223    04913 Ovarian steroidogenesis     106968223    04915 Estrogen signaling pathway     106968223    04914 Progesterone-mediated oocyte maturation     106968223    04921 Oxytocin signaling pathway     106968223    04926 Relaxin signaling pathway     106968223    04935 Growth hormone synthesis, secretion and action     106968223    04918 Thyroid hormone synthesis     106968223    04928 Parathyroid hormone synthesis, secretion and action     106968223    04916 Melanogenesis     106968223    04925 Aldosterone synthesis and secretion     106968223    04927 Cortisol synthesis and secretion     106968223   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     106968223    04270 Vascular smooth muscle contraction     106968223   09154 Digestive system    04970 Salivary secretion     106968223    04971 Gastric acid secretion     106968223    04972 Pancreatic secretion     106968223    04976 Bile secretion     106968223   09156 Nervous system    04724 Glutamatergic synapse     106968223    04727 GABAergic synapse     106968223    04725 Cholinergic synapse     106968223    04720 Long-term potentiation     106968223    04723 Retrograde endocannabinoid signaling     106968223   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     106968223   09149 Aging    04211 Longevity regulating pathway     106968223    04213 Longevity regulating pathway - multiple species     106968223   09159 Environmental adaptation    04713 Circadian entrainment     106968223    04714 Thermogenesis     106968223  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     106968223    05207 Chemical carcinogenesis - receptor activation     106968223   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     106968223    05163 Human cytomegalovirus infection     106968223   09174 Infectious disease: parasitic    05146 Amoebiasis     106968223    05142 Chagas disease     106968223   09165 Substance dependence    05032 Morphine addiction     106968223   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     106968223   09167 Endocrine and metabolic disease    04934 Cushing syndrome     106968223   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     106968223 Enzymes [BR:aju01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      106968223 SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom Motif Other DBs NCBI-GeneID:  106968223 NCBI-ProteinID:  XP_053074726 UniProt:  A0ABM3PSR4 LinkDB All DBs Position 4 Genome browser AA seq 1132 aa AA seqDB search MAGAPRGRGGGGGGGGGGAGEPGGAERAARPGGRRGLRACDEEFACPELEALFRGYTLRL EQAATLKALAVLSGLAGALALAELLGAPGPAAGLARGSHPAHCVLFLALLVVTNVRSLQV PQLQQVGQLALLFSLTFALLCCPFALGRPAGTLAGAASGPATADQGVWQLLLVTFVSYAL LPVRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLSVNMYGVFVRILAE RSQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYI QRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYC VSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQY DVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKAHNIETFFI VPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVLTCEDDDKR RALRTASEKLRNRSSFSANAVYTTPGTRVNRYIGRLLEARQTELEMADLDFFTLKYKQAE RERKYHQLQDEYFTSAVVLALVLAALFGLVYLLIIPQNLVLLLLLAFCICFLVACVLYLH ITRVQCFPGCLTIQIRTVLCIFVVVLIYSVAQGCVVGCLPWSWSSTPNGSLVVLTPSGRN AVLPAAPCESAPHALLCGLVGTLPLAVFLRVSSLPKMILLFVLTTSYILVLELSGYTRAP GGGVASGRSFEPIMAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMERVKLDNKR ILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFDDFYIELDGNNMGVECLR LLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTTGTKAKKGISSHLSTLADFA IEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQ GRIQVTEEVHRLLRRGTYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQARERKVCGYGR AGLQGRLGTGPPPVSSMAGLPVRAGMGALQGSGLPPCPYGQHLPPGAAGKEA NT seq 3399 nt NT seq  +upstreamnt  +downstreamnt atggcgggggcgccgcgcggccgaggcggaggcggcggcggaggcggaggcggcgcgggc gagcccgggggcgcggagcgggcggcccggccgggcggccggcgcgggctgcgggcgtgc gacgaggagttcgcgtgccccgagctggaggcgctgttccgcggctacacgctgcggctg gagcaggcggctacgctgaaggcgctggcggtgctcagcgggctggcgggcgcgctggcg ctggccgagctgctgggcgcgccggggcccgcggccggcctggcccggggctcgcacccc gcgcactgcgtgctcttcctggcgctgctcgtggtcaccaacgtgcgctcgctgcaggtg ccccagctgcagcaggtcggccagctggcgctgctcttcagcctcaccttcgcgctgctg tgctgccccttcgcgctcggccgccccgcggggaccctcgccggcgccgcttcggggccg gcgaccgccgaccagggcgtgtggcagctcctgctggtcaccttcgtgtcctatgccctg ctgcccgtgcgcagcctgctggccatcggcttcgggctcgtggtggccgcctcgcacttg ctggtcacggccaccttggtacccgccaagcgcccgcgtctctggaggacgcttggtgcc aacgccctgctcttcctcagcgtgaacatgtatggggtgtttgtgcgcatcctggccgag cgctcccagcggaaagccttcctgcaagcccggaactgcatcgaagatcggctgaggttg gaggatgagaacgagaagcaggagcggctgctcatgagccttctgccccggaatgttgcc atggagatgaaggaggacttcctgaagccccccgagaggattttccacaagatttacatc cagcggcatgacaacgtgagcatcctctttgcggacattgtgggcttcacgggcctggcg tcgcagtgcacggcacaggagctggtcaagctcctcaacgagctgttcggcaagtttgat gaactggccacggagaatcactgtcgccgcatcaagatcctaggggactgttactactgt gtgtccggcctcacccagcccaagaccgaccacgcccactgctgcgtggagatgggcctg gacatgatcgacaccatcacgtctgtggccgaggccacggaggtggacctgaacatgcgc gtggggctgcacacaggcagggtcctctgcggggtcctgggcctgcgcaagtggcagtac gacgtgtggtccaacgacgtgaccctggccaatgtcatggaggcggctggcctacctggg aaggtccacatcacgaagacgaccctagcgtgcctgaatggggactacgaggtggagccg ggtcacggacacgagaggaacagttttctgaaagctcacaacatcgagaccttcttcatc gtgccgtcacatcggcggaagatatttccagggctgatcctctctgacataaaaccagcc aagaggatgaagttcaagaccgtgtgctacctgcttgtgcagctgatgcactgtcggaag atgttcaaggcagagatcccgttctctaacgtcctgacgtgtgaggacgacgacaagcgg agggcgctgagaaccgcgtcggagaaactgcgaaaccgctcgtcgttctccgcaaacgcc gtctacaccaccccgggcacgcgcgtcaacaggtacattggccgcctcctggaagcgcgc cagacagagctggagatggcggacctggacttcttcaccctcaagtacaagcaggctgag cgggagcgcaagtatcaccagctccaggacgagtattttaccagcgccgtcgttctggcc ctcgtcctggccgccttgttcggcctcgtctacctgctcatcatcccacagaacctggtc ctcctgctgctgctggccttctgtatctgcttcctggtggcctgcgtcctgtacctgcac atcacccgggtccagtgttttccagggtgcctgacgattcagatccgcaccgtcttgtgt atcttcgtcgtggtcttaatctactccgtggcccaaggatgtgtggtgggctgcctgccc tggtcctggagctccacccccaatgggtccctggtggtcctgacgcccagcggccgcaac gccgtgctgcctgccgcgccctgtgagtcggcgccccacgccctgctctgcggccttgtg ggtaccctcccgctggctgtcttcctgcgggtgtcctccctgcccaaaatgatcctgctc tttgtgctcacgacgtcctacatcctggtcctggagctcagcggctacaccagggccccc gggggcggcgtggcatcggggcgcagtttcgagccgatcatggccatcctgctgttttcc tgcaccctggccctgcacgcccgtcaggtggacgtcaagctgcggctggactacctctgg gcagcacaggcagaggaggagagagatgacatggagagggtgaagttggacaacaagagg attctcttcaacctcctgccggcccacgtggctcagcacttcctcatgtccaacccccgc aacatggacctgtactaccagtcctactcacaggtgggcgtcatgtttgcttccatcccc aacttcgacgacttctacatcgagctggacggcaacaacatgggggtggagtgtctgcgt ctcctgaacgagatcatcgcagacttcgacgagctcatggacaaagacttttacaaggac ttggagaagatcaagaccatcgggagcacctacatggccgctgtggggctggcgcccacc actgggaccaaggccaagaagggcatctcctcccacctgagcacactggctgacttcgcc atcgagatgttcgacgtcctggatgaaatcaactaccagtcttacaacgactttgtgctc cgtgtgggcatcaacgtgggccctgtggtggccggggtgatcggggctcggaggccacag tacgacatctgggggaacacagtcaacgtggccagtcggatggacagcaccggcgtccag ggcagaatccaggtgaccgaggaggttcaccggctgctgcgccgggggacctaccgcttc gtgtgccgcgggaaggtcagcgtcaagggcaagggtgagatgctgacgtacttcctggaa ggcaggacggacggaaacggctcccaagccagggagcggaaagtgtgtggctacgggcga gccggcctccagggcagactgggcacaggcccacccccggtgtcctccatggccggcctc ccggtcagagccgggatgggggctctgcagggctcagggctccccccctgcccctacggc cagcacctgccccccggagcagctgggaaggaggcttag

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