Poseidonibacter lekithochrous: ALEK_0178
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Entry
ALEK_0178 CDS
T06860
Symbol
metH
Name
(GenBank) cobalamin-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
alk
Poseidonibacter lekithochrous
Pathway
alk00270
Cysteine and methionine metabolism
alk00450
Selenocompound metabolism
alk00670
One carbon pool by folate
alk01100
Metabolic pathways
alk01110
Biosynthesis of secondary metabolites
alk01230
Biosynthesis of amino acids
alk04981
Folate transport and metabolism
Module
alk_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
alk00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
ALEK_0178 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
ALEK_0178 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
ALEK_0178 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
ALEK_0178 (metH)
04980 Cobalamin transport and metabolism
ALEK_0178 (metH)
Enzymes [BR:
alk01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
ALEK_0178 (metH)
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding
B12-binding_2
CdhD
Motif
Other DBs
NCBI-ProteinID:
QKJ21498
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Position
173921..177397
Genome browser
AA seq
1158 aa
AA seq
DB search
MIEKFKKLIDDKVLVIDGAMGTQLQLADIKAQEWMYEGADLEGCNELLNLTAPHVLRTIH
DAYAKAGADLITTNTFGSMSWVLDEYDIPQTAYELSKLGASLVKESCVKYSTASKPRFVL
GSIGPGTKLPSLGHIKYDDMYEGYKEMAEGLRDGGTDIFLLETCQDPLQIKAALHALTDA
APQIPIMVSVTIEMSGTMLIGTDALTIAAIMEPFNILSLGFNCGTGPKQVFKHVKTLSEV
CKFPISVHANAGLPQNRGGQTYYPMGPDEFTSLQKEFLDINGVSFLGGCCGTTPEHIKVL
SETIEGIVPKKPNGFLKASLASLFNTVPLKQDPAPLLIGERSNATGSKAFRELLKANNYE
GTLSVGQQQVRAGAHIIDVSVGFAGRDEKDDMDKVVELYSQKVSLPLMPDSTQITALEAA
LKQIGGRPIINSVNLEDGEEKFDAVCKLAKKFGAALVCLTIDEVGMAKTKEDKIRMAERI
YDLCVNRHGFNPADLVFDMLTFTIGSGDDEYRSAGIETMEAIREFQILHPEVGTTLGLSN
ISFGLDIKARVYLNSIYLDHCVKAGLTSAIVNVKHILPLNKITEEDRKACDDLIFDNQEN
GDPLFAFIDHFSNVEAQEEESDEEYQKLPAVEKVKKLLLDGDKDRMLPLVDELRLEVKPE
VIVNEWLIDGMKIIGELFGSGQMQLPFVLQSAETMKATVDALNPYLPKEEKATETVLVIG
TVKGDVHDVGKNLVDIILSNNGFKVINIGIKADLNDFIIAVKEHKADAIGMSGLLVKSTA
VMKDNLEELHKLGIDIPVLLGGAALTKAFINDYCRPIYDGPIFYCRDAFDGVVSMQRIES
GDADNTALAADLIEVVDTSDKVEKEEVIIPPYEEIELPKPAEFTFPPIWDRIARTGDKVD
KELIFKWINHRVLYRQRWGYKRGKQSSEKFLKHEEEVVKPMYEELKAELIDKNIFDPIAI
YAYYPCISHDNKIYIFDKEYLFNNEKEAKNVPSLDKAIKVLEFPRQKRKPFRCIADYFAN
DRLDVIAFTLASAGLKVADYEREFYNKGEFTKYYQIHGLGVELAEALAEVLHKQVRLDLD
IVPKEGHTLNDVQMKQYVGCRYSPGYAACPDLAMNRDIFDLLNPEEFGIELSETFQMHPE
QTTCAIVVPHFDAKYYNI
NT seq
3477 nt
NT seq
+upstream
nt +downstream
nt
atgatagaaaaattcaaaaaattaatcgacgacaaagtactggtaattgacggagctatg
gggacacagcttcaacttgctgatattaaagctcaagagtggatgtacgaaggtgcagat
ttagaagggtgtaatgaacttctaaatttaactgctcctcatgtattgagaactattcat
gatgcttatgcaaaagcaggagcagatttaataacaactaatacttttggttcaatgtca
tgggttttagatgaatacgatattcctcaaactgcttatgaattatcaaagttaggagca
tctttagtaaaagaatcttgtgttaaatatagcactgcttcaaaaccaagatttgtttta
ggatcaattggacctggaacaaaacttccatcattaggtcatattaaatatgacgatatg
tatgaaggttataaagaaatggcagaaggattaagggatggtggaacagatattttctta
cttgaaacttgtcaagatccattacaaattaaagccgcacttcatgccttaacagatgct
gctccacaaataccaattatggtatctgtaactattgaaatgtcaggaactatgcttatt
ggtactgatgctttaacaattgcagctattatggaaccttttaatattttatcacttgga
tttaactgtggtacaggaccaaaacaagtatttaaacatgttaagactttaagtgaagtt
tgtaaattcccaatatcagttcatgcaaatgcaggacttcctcaaaatagaggtggtcag
acttattatccaatgggacctgatgagtttacttctttacaaaaagagttcttagatatt
aatggagtttctttcttaggtggatgttgtggtacaacacctgagcatattaaagtttta
agtgaaacaattgaaggaatagttcctaaaaaacctaatggtttcttaaaagcttcctta
gcatcattatttaatacagttccattaaagcaagatccagcacctctacttattggtgag
agatcaaatgcaactggttctaaagcctttagggaattactaaaagcaaataattatgaa
ggaacactttctgttggacaacaacaagtaagagctggagcacatattattgatgtatct
gttggatttgcggggcgtgatgaaaaagatgatatggataaagttgttgagctttactct
caaaaagtatcacttccacttatgccagattcaactcaaattacagctttagaagcagca
cttaaacaaattggtggaagaccaattatcaactctgttaacctagaagatggagaagaa
aaatttgatgcggtttgtaaactagctaagaaatttggagcagcattagtttgtcttact
attgatgaagtaggaatggctaaaactaaagaagacaaaatcagaatggcagaacgtatt
tatgatttatgtgtaaatagacatggctttaatcctgcagatttagtatttgatatgctt
acatttactattggttctggtgatgatgagtatagaagtgcaggtattgaaactatggaa
gctattagagaattccaaatacttcacccagaagtaggaactactttaggtctttcaaat
atctcatttggtttagatattaaagcaagagtttatttaaattcaatttatttagatcat
tgtgtaaaagctggattaacatctgcaattgtaaatgtaaaacatatcttacctcttaat
aaaattacagaggaagacagaaaagcttgtgatgacttaatctttgataatcaagaaaat
ggagatccattatttgcctttattgatcacttctcaaatgtagaagctcaagaagaagag
agtgatgaagagtatcaaaaacttcctgctgttgagaaagttaagaagttattacttgat
ggtgataaagatagaatgcttcctttagtggatgaattaagacttgaagtaaaacctgaa
gttattgtaaatgaatggttaattgatggtatgaaaataattggggaactatttggttct
ggacaaatgcaattaccatttgtacttcaaagtgctgaaactatgaaagcaacagttgat
gcattaaatccatatttaccaaaagaagaaaaagcaactgagacggtattagtaatagga
actgtaaaaggtgacgtgcatgatgttggtaaaaacttagtagatattattctttcaaat
aatggatttaaagttattaatattggtattaaagctgatttaaatgactttattattgca
gttaaagagcataaagctgatgctattggtatgagtggattacttgtaaaatcaactgct
gttatgaaagataatttagaagaattacataaattagggattgatattcctgtattactt
ggaggggctgcacttacaaaagccttcattaatgactattgtagacctatttatgatgga
ccaattttctattgtagagatgcttttgatggtgttgtttctatgcaaagaattgaaagt
ggagatgcagataatacggctttagcggctgatttaattgaagttgttgatactagtgat
aaggttgagaaagaagaagttattattcctccatatgaagagatagaacttccaaaacca
gctgagtttactttccctccaatttgggacagaatcgctagaactggagataaagttgat
aaagaattaatattcaaatggattaaccatagagtattatatagacaaagatggggatat
aaaagaggtaagcagtcaagtgaaaagttcttaaaacatgaagaagaggttgtaaaacct
atgtatgaagagctaaaagcagaattaattgacaaaaatatttttgatccaattgcaatt
tatgcttattatccttgtatttctcatgataataaaatttatatctttgataaagagtat
ttatttaataatgaaaaagaagcaaaaaatgttccttctttagataaagcaattaaagta
cttgaattccctagacaaaagagaaaaccatttagatgtattgctgattattttgcaaat
gataggctcgatgttattgcctttactcttgcaagtgctgggcttaaagttgctgattat
gaaagagaattttataataaaggtgagtttactaaatactaccaaatccatggattaggt
gttgagcttgctgaagctttagctgaggttttacataaacaagtaagacttgatttagat
attgttccaaaagaagggcatactttaaatgatgttcaaatgaaacaatatgtaggttgt
agatactctcctggatacgctgcttgtccagatttagcaatgaatagagatatcttcgat
ttattaaatcctgaagagtttggaatcgaattatctgaaacattccaaatgcatcctgag
caaacaacttgtgctatagttgttcctcactttgatgcgaaatactacaatatatag
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