Actinomadura madurae: LUW76_11530
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Entry
LUW76_11530 CDS
T08933
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
amaz
Actinomadura madurae
Pathway
amaz00010
Glycolysis / Gluconeogenesis
amaz00020
Citrate cycle (TCA cycle)
amaz00620
Pyruvate metabolism
amaz00785
Lipoic acid metabolism
amaz01100
Metabolic pathways
amaz01110
Biosynthesis of secondary metabolites
amaz01120
Microbial metabolism in diverse environments
amaz01200
Carbon metabolism
amaz01210
2-Oxocarboxylic acid metabolism
Module
amaz_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
amaz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
LUW76_11530 (aceE)
00020 Citrate cycle (TCA cycle)
LUW76_11530 (aceE)
00620 Pyruvate metabolism
LUW76_11530 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LUW76_11530 (aceE)
Enzymes [BR:
amaz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
LUW76_11530 (aceE)
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Paralog
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transket_pyr
Radical_SAM
Motif
Other DBs
NCBI-ProteinID:
URN01567
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All DBs
Position
2474865..2477624
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AA seq
919 aa
AA seq
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MSDGLPSQLPDINPDETREWLESLDTVIKTEGRGRARYVMLRLLERAREQQVGVPGLRST
DFINTIPPESEPWFPGDEHVERRIRAYIRWNAAIMVSRANRPELGVGGHIATYASAASLY
EVGFNHFFRGKDHGESGDQVFIQGHAAPGIYARAFLEGRLPEDKLDGFRQEHSHPGGGLS
SYPHPRLMPDFWEFPTVSMGLTAIDSVYQARFNRYMYSRKIKDTSRSHVWAFLGDGEMGE
PESLGAIGLAAREELDNLTFVVNCNLQQLDGPVRGNGKIIQELESFFRGAGWNVIKVIWG
RDWDPLLAQDVDGVLVNQMNTTPDGQFQTFSVESGEYIREKFFGADPRLRKIVQHLSDDD
LRKLSRGGHDYRKVYAAFKSAREHVGQPTVILAHTIKGWTLGSDFEARNATHQMKKLTKA
ELKEFRDRLYLDIPDSALEAPLPPYYHPGEDSDEIQYMRERRAALGGFLPKRVVRAKPLK
LPGDPVYSEMKKGSGKQNVATTMAFVRLLKDLIKDENIGARFVPIAPDEYRTFGMDSLFP
TSKIYSPQGQTYDAVDRKLLLSYKESESGQMLHEGISEAGSMASTIAAGTAYATHGEHMI
PVYIFYSMFGFQRTGDQMWALGDQMGRGFLLGATAGRTTLTGEGLQHADGHSPLLAATNP
ACVHYDPTWAFELAHIVKDALRRMYGTSEEHPNGEDVFYYLTVYNEPYQQPAEPENLDVD
GLLKGLYRYREAPEVASGNGETPRAQILASGVGGRWALEAQRLLAEDWGVAADVWSATSW
NELAREARDCDEWNLLNPDAEQRVPYVSRTLDSVAGPIVAVSDFTRAVPDQIAPWVHGDF
SSLGTDGYGFSDTRAAARRFFHVDAASVVLAVLTRLARHGEVKPETLSQAIKRYRLDAGV
SDVFAGGVGSAESNTGGDA
NT seq
2760 nt
NT seq
+upstream
nt +downstream
nt
atcagcgacggcctgccgagccagctgcccgacatcaacccggacgagacccgggagtgg
ctggagtcgctggacacggtcatcaagacagaaggccgcggcagggcgcgctacgtgatg
ctgcggctcctggagcgggcgcgcgagcagcaggtcggcgtgcccggcctgcgcagcacc
gacttcatcaacaccatcccgccggagtccgaaccctggttccccggcgacgagcacgtc
gagcggcgcatccgcgcctacatccgctggaacgcggcgatcatggtgtcccgggccaac
cggcccgagctcggcgtcggcggccacatcgccacctacgcctccgccgcctccctgtac
gaggtgggcttcaaccacttcttccgcggcaaggaccacggcgagtccggcgaccaggtc
ttcatccagggccacgccgcccccggcatctacgcccgcgccttcctggagggccggctg
cccgaggacaagctcgacgggttccggcaggagcactcgcacccgggcggcggcctgtcg
tcctacccgcacccgcggctcatgccggacttctgggagttccccacggtgtccatgggc
ctcaccgcgatcgactcggtgtaccaggcgcggttcaaccgctacatgtacagccgcaag
atcaaggacacgtcccggtcgcacgtgtgggcgttcctcggcgacggcgagatgggcgag
ccggagtcgctcggcgcgatcggcctcgccgcccgcgaggagctcgacaacctcaccttc
gtcgtcaactgcaacctgcagcagctcgacggcccggtgcgcggcaacggcaagatcatc
caggagctggagtcgttcttccggggcgccggctggaacgtcatcaaggtcatctggggc
cgcgactgggacccgctgctcgcgcaggacgtcgacggcgtgctggtcaaccagatgaac
accaccccggacgggcagttccagacgttcagcgtcgagtccggcgagtacatccgggag
aagttcttcggcgccgacccgcggctgcgcaagatcgtccagcatctgtcggacgacgac
ctgcgcaagctgtcccgcggcgggcacgactaccgcaaggtgtacgcggcgttcaagtcg
gcccgcgagcacgtcggccagccgaccgtcatcctggcgcacaccatcaagggctggacg
ctcggctccgacttcgaggcccgcaacgccacccaccagatgaagaagctcaccaaggcc
gagctgaaggagttccgggaccggctctacctggacatccccgactcggcgctggaggcc
ccgctgcctccctactaccacccgggcgaggactccgacgagatccagtacatgcgcgag
cgccgcgccgccctcggcgggttcctgccgaagcgggtcgtgcgggccaagccgctcaag
ctgccgggcgaccccgtctacagcgagatgaagaagggctccggcaagcagaacgtcgcc
acgaccatggcgttcgtccggctgctcaaggacctgatcaaggacgagaacatcggtgcc
cggttcgtgccgatcgccccggacgagtaccgcacgttcggcatggactcgctcttcccc
acgtccaagatctactcgccgcaggggcagacctacgacgcggtggaccgcaagctgctg
ctgtcgtacaaggagtccgagagcggccagatgctgcacgagggcatcagcgaggccggc
tcgatggcgtccaccatcgccgcgggcaccgcgtacgccacgcacggcgagcacatgatc
ccggtctacatcttctactcgatgttcgggttccagcggaccggcgaccagatgtgggcg
ctcggcgaccagatgggccgcggcttcctgctcggcgccaccgccgggcgcaccaccctc
accggcgagggcctccagcacgccgacggccactccccgctcctcgcggcgacgaacccg
gcgtgcgtccactacgacccgacgtgggcgttcgaactggcgcacatcgtcaaggacgcg
ctgcgccgcatgtacgggacgtccgaggagcacccgaacggcgaggacgtcttctactac
ctcaccgtctacaacgagccgtaccagcagcccgccgagcccgagaacctcgacgtcgac
gggctcctcaagggcctgtaccggtaccgggaggccccggaggtcgcctccgggaacggc
gagaccccgcgggcgcagatcctcgcgtccggcgtcggcggccggtgggccctggaagcc
cagcgcctcctcgccgaggactggggcgtcgccgcggacgtctggtcggcgacgtcgtgg
aacgagctggcccgcgaggcccgcgactgcgacgagtggaacctgctcaaccccgacgcc
gagcagcgcgtcccctacgtctcccggacgctcgacagcgtcgccgggccgatcgtggcg
gtatcggacttcacccgcgccgtgcccgaccagatcgcgccctgggtgcacggggacttc
tcctcgctcggcaccgacgggtacggcttctccgacacccgcgccgccgcccgccggttc
ttccacgtggacgccgcgtcggtcgtcctcgcggtgctcacccggctcgcccggcacggc
gaggtcaagccggagaccctgtcgcaggccatcaagcgctaccgcctcgacgccggcgtc
agcgacgtcttcgcgggcggcgtaggcagcgccgagagcaacacgggcggcgacgcttga
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