Amycolatopsis mediterranei U32: AMED_1985
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Entry
AMED_1985 CDS
T01269
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
amd
Amycolatopsis mediterranei U32
Pathway
amd00010
Glycolysis / Gluconeogenesis
amd00020
Citrate cycle (TCA cycle)
amd00620
Pyruvate metabolism
amd00785
Lipoic acid metabolism
amd01100
Metabolic pathways
amd01110
Biosynthesis of secondary metabolites
amd01120
Microbial metabolism in diverse environments
amd01200
Carbon metabolism
amd01210
2-Oxocarboxylic acid metabolism
Module
amd_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
amd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
AMED_1985 (aceE)
00020 Citrate cycle (TCA cycle)
AMED_1985 (aceE)
00620 Pyruvate metabolism
AMED_1985 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AMED_1985 (aceE)
Enzymes [BR:
amd01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
AMED_1985 (aceE)
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Motif
Pfam:
Transketolase_N
PDH_E1_M
Transketolase_C
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
ADJ43793
UniProt:
A0A0H3CZN1
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Position
2122047..2124326
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AA seq
759 aa
AA seq
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MTAPALTAIEQRVLWLATAIVHQANRVRPNPSGLKVGGHQASCASLVSIMTSLWFRHLRP
EDRVSVKPHASPVLHAINYLLGELDEAYLPTLREFGGLQSYPSRAKDPDPVDYSTGSVGI
GATAPIWGALARRYLTTRGSSAGTGRQYSLVGDAELDEGAIWEAILDPAVAELGEIVWIV
DLNRQSLDRVVPNIAAGRLQGMFDAAGWQVLALKYGRLLEELFTRPGGAELRARIDGMPN
PEYQRLLRCDAAQLRDRLPAGNPALSALVASLDDETLLAAIRNLGGHDLGSLDEVFASVA
DDRPTVIFCYTVKGRGLPTQGHPQNHSSLLTVAQMEELASALGTDLASPWERFADGSPEG
ALCAEVASRLRRPDVPSVPSLELPVDIGRTPSGTATTQAALGRVLLDLTREAPEAAKRVV
TVSPDVSSTTNLGGWVNKVGVWSATERRDWFEDDPETIMHWREKPTGQHVELGIAETNLV
GLLGELGATWSRWGEPLLPIGVMYDPFVERALEPWSFGIYAGGQSILIGTPSGVTLAPEG
GAHQSITTPSIGIEQPGCVSYEPAFAIDTEWTLLAALGRLGKPGGTSSYFRLSTRPVDQT
LAAVPTDPAARERRRRQVVAGAYLLRRAASPAVTLAAMGALVPDTLAAAERLAQVGVEAD
VVCVTSPGLLFEALQARSGRGSAESWILDRVFPASRAKPLVTVLDGHPHTLAFLAGINRV
PSVALGVTGFGQSGSLEDVYRYHGIDTDAIIRAALDAVS
NT seq
2280 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgccccggcgctcaccgcgatcgagcagcgggtgctgtggctcgccaccgcgatc
gtgcaccaggccaaccgggtccgcccgaatccgtccgggctcaaggtcggcggccaccag
gcgtcgtgcgcgtcgctggtctcgatcatgacgtcgctgtggttccggcacctgcgtccc
gaagaccgcgtctcggtgaagccgcacgcgtcgccggtgctccacgcgatcaattacctc
ctcggcgagctcgacgaggcctacctgccgacgctgcgcgagttcggcggcctgcagagc
tacccgagccgcgccaaggaccccgacccggtggactactcgaccggctcggtcggcatc
ggcgcgaccgccccgatctggggcgcgctggcccgccgctacctgacgacccggggctcg
tcggcgggcaccggccgccagtactcgctggtcggcgacgccgagctcgacgaaggcgcg
atctgggaggccatcctcgacccggcggtcgccgaactgggcgagatcgtctggatcgtc
gacctcaaccgccagtccctcgaccgggtcgtcccgaacatcgcggccgggcggctgcag
ggcatgttcgacgccgccggctggcaggtcctggcgctgaagtacgggcggctgctggag
gagctgttcacccggcccggcggcgccgagctgcgcgcccgcatcgacgggatgccgaac
cccgagtaccagcggctgctgcgctgcgacgccgcgcagctgcgcgaccggctgcccgcg
ggcaatccggctctctccgcgctggtcgcgtcgctcgacgacgagacgctgctggccgcc
atccgcaacctcggcgggcacgacctcggctcgctcgacgaggtcttcgcgtccgttgcg
gacgatcggccgacggtgatcttctgctacaccgtcaagggacgcggtcttcccacgcag
gggcacccgcagaaccactcctcgctgctgaccgtggcgcagatggaagagctggcgtcg
gctctgggcacggacctcgcttcgccgtgggagcgcttcgctgacgggtcgcccgaaggc
gcgttgtgcgctgaggtcgcttcgcgccttcgccgtccggacgttccttcggtgccttcg
ctggaactgcccgtcgacatcggacgtacgccgtcaggcaccgcgacgacgcaggccgcg
ctgggccgcgtgctgctcgacctgacgcgcgaagcgcccgaagcggcgaagcgcgtggtg
acggtcagccccgacgtcagctcgacgaccaacctcggcggctgggtcaacaaggtcggc
gtctggtcggccaccgagcgccgcgactggttcgaggacgaccccgagacgatcatgcac
tggcgggagaagccgaccggccagcacgtcgagctgggcatcgccgagacgaacctggtg
ggcctgctgggcgagctcggcgcgacctggagccggtggggcgagccgctgctgcccatc
ggcgtcatgtacgacccgttcgtcgagcgcgcgctcgagccgtggtcgttcggcatctac
gcgggtgggcagtcgatcctgatcgggacgccgtcgggggtcacgctcgcgccggaaggc
ggcgcgcaccagtcgatcaccacgccgtcgatcgggatcgagcagcccggctgcgtcagc
tacgaaccggcgttcgcgatcgacaccgagtggaccctgctggccgcgctcggccggctc
ggcaagccgggcggcacgtcgtcgtacttccggctctcgacgcgtccggtcgaccagacg
ctcgccgcggtgcccaccgacccggccgcccgcgaacgccgtcgccggcaggtcgtggcg
ggcgcgtacctgctgcggcgtgcggcttcaccggcggtcacgctggcggcgatgggcgcg
ctggtgccggacaccctggcggcggccgagcggctggcccaggtcggcgtcgaggccgac
gtcgtgtgcgtgaccagtccgggcctgctgttcgaggcgctccaggcccggtccggccgg
gggagcgccgagtcgtggatcctcgaccgggtgttcccggcttcgcgggcgaagccgctg
gtcaccgtgctcgacggccacccgcacacgctggcgttcctggccgggatcaaccgggtg
ccgtcggtcgctctcggcgtcacgggtttcgggcagtcggggtcgctcgaggacgtctac
cgctaccacggcatcgacacggacgcgatcatccgggccgcgctcgacgccgtcagctga
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