Astyanax mexicanus (Mexican tetra): 103034817 Help Entry 103034817         CDS       T05042                                  Symbol syne1a Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism amex  Astyanax mexicanus (Mexican tetra) Pathway amex04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:amex00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     103034817 (syne1a)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:amex03036]     103034817 (syne1a) Chromosome and associated proteins [BR:amex03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     103034817 (syne1a) SSDB OrthologParalogGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 CH SYNE1 KASH Spectrin_SYNE1_2 SR_desmoplakin_3 Motif Other DBs NCBI-GeneID:  103034817 NCBI-ProteinID:  XP_022518815 Ensembl:  ENSAMXG00000006306 LinkDB All DBs Position 1:complement(79182653..79426179) Genome browser AA seq 8897 aa AA seqDB search MAHMWQDLSTKRKKSGASLNLVAGVSQHLRDEQEAVQKRTFTKWINSHLAKRDPPLVVKD LYEDIKDGVMLLALLEVLSGHKLPCEQGRKLRRIHWLANVGTALRFLEGRRSVYRGSPIK LVNINTTDVVDGRPSIVLGLIWTIILYFQIEELTSSLPPQKGQNSSNSSVDSSNSTETAS PPVKRKPRLSFQGGAKRALLKWVQRTATKRLGLDVKDFGPSWRSGVAFHAVIFALRPQLV NMERVWNRPNRANLEEAFSLAERELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHHPDG GEAESVGQQEEREQRKVLRELKVWADQLEKDCAQAQMDKGDPGHQYKSFKQYRVQYELKR RQVLSSLQSTQRDGILTSDQALFKQAWERISTRLLDWHIQLDSALPNPLGAVGIWLHQAE KILQEEPLPQQSHEQTANAIHQTLQQHQEILGLFETHQQTFQQLHRDRSVSGVPVPAEQL QDMAERLNYISTSSHVHLSKLEFWELKYRMLALLTLGESKLKSWIVKYGRLETTQLLLQS YVSFVEGQQFFQKYESLYEDLKQAAVLYTNADSSAEEAVRRFLRDMADQWRSLAVEIRSV RSMLKEVEGNWEKYSSAVSSLQAWLEDAQVALHQPENTKREFFRNLPHWMDQHTTMNDSG NFLIETCDETVSRDLKHQLLLLNGRWRDMFIKAKQYACMHETQIQTEKEQQEAIAALKDF IQTSTAKLTSPVQLSLPDVGSFVEDVEAIIHRLPAVEVQYKTAARSAQLRARDTVNGDRR QTLTTMASIKGQLYKMKEKCPVVLRECQTVIPLLEELERQISAFYQTAERAGHIITQQHD QHKNRELLSQQQSCQRCVCVVERSYLALQRALCCTKTLYNFDPSLLQNRVTELQTTAQVL MQEALEWRRVAETNGNLTRRFEESRAELEKALRVGQACLKERGDPAELLSKHNDFFGRLD QRVLNAYLKACDDLTDILPEEEQQGLQESVRRLHKQWKDIQAEAPAHLLRLKVEAERRIV LASLQECRIELQKEDKAIATSGSERVIREHRVYFRQKDPLAVCERRLKTMEQLCQKLPEN DPMQRALLETKDHLLEVRDEVERTYVRFQQHPDKWREWHARFKELSGWLSSQQDKQRSGE CCTVQHGVLKGHVDALDWLKTRLSVLEDVSTEAEVLTQTTALEDLSIQFNFHVSSLEEDM SVNGHSESGQEELQQEEGLPQPQEHSRILNAESAAEARQLLLIHQQRLKSQQRKKHAEPQ GLCTRSYGALMDREEEHSWATQEELLQSIVRAWQDFEQDREAVGQFVCSATPILQRERIF SSLENLTTELDHAQELHRKTGVITEQAKSLVKKAAEIQLGAQNHSLLHDQAQAAQERVQE IHISLEKMIMGLEKMQVRWQNFNSESEAFSSWVCEREKELEALDLNSAHLDQQLQTVEAM EAGLEERMKVLSQLESESHALARFITPGGAERIKARLIQIGRYWEELRSNVKQRGMELQA SVLHKVKLNEDLEEVINAVKALEDKLNKPIASCFSSSATYQTLHDHMDVWQALKQLQPRL VSLSLGLRRLCDGGQVEKAVADLQHAHTECTQKAASKQAMLEDLLSLWQKYERDLSVLQG WLDRCEFLCTSEKLYLTTDKSKLQSQLQMLQDLQSEVPSQESLLEKLENQAESLYPTASE ERVGELTELHCSLEERWCSLSTNIPLRIQELQAHLAQLEQFNQALVTFTLWSENFLGELR RKSKVTISDLISVKTQIKEDEALLQTQREAIDGLQQHMDALGPSLSPEDLQRLQVRKEDC LQPVCEAQSLLQRRSEALGKLETFLVTYRSATNSVQTHQGAVEGRGSWDQAKAEQLNQDL GQLAQKLASLEVQAISLDSSLNKASLHLHRAEGERTSCRRLVDEQGSGLQRLQRSLGTRQ SEAETLAGLWNSFRGRKELLLRSLMELEEKVRKTWLTEPSTQNFQQRLWMLDQLEEELQA LQHSQLWLGERGEQLSHRDSEMSEEVQQDVTLVQSTWERIQRLITEEQEQCAVLLDVCKD YFTLKSRITSAVERAHAVTAAQSGQHNPEDIRRALSRLEAVKPELAGTQEELNLFISKGK HLISELRKLPEHTGESVRTEMDCIVDRWLDTSERLDSDIDHLTVFLALWNEINSIANDIE CWTATSVSELSEGAVNLLSSSNVDEQLAQFKLELESKEEVLKVLQRKVTELQEVTKTQQT PAELQTMEADLRKKIIHAGEVYEQTRSIVKDFGVQRQQLQDIISQLAEQLETIEDTLSEL SQSSDPENVAKIKDLQSTLKQVDGGLDVAGETLRTLCRAHPAQQLTQHGEEITDLVKRSE AAVQRSTCILGKLQEVLLQHFNELAQGFHHWLSELRAGTEDGPEQTGEVPDITAQLHRLK ITLERAGEGEKYMARLNEDGERLLSLLTKTGAGGVQERLASSQLALDGFVVACRQRLRSI EESAALQDGFEVRVDELRAWLQQIAAKLQGEPALWGESKQGSSDCSAQLERMEELHKELL MRRPSLERSCQAFLTLSDGRAGDPEASQTMELLSSHQALVQEAWVRLRGLQEYQAFNEAL RAMGDWLEEVEEKLEKLESTEGDKKEVEERLERVQDILLMKGEGEVKLNMAAGKGELVIK SSGEAGQDVIHFKLQEVEDAWAALLLRAMSCHSRLEWTVSQWGLFVESRAQLQGWLEQVE AEVKGPLEPQLGLREKRQQLDRLCLLSADVEDHQGALCYLEESAAELYKRTGDATFREDE TALLRAQFDDVRAATEERVRFSECVVFEHEKYMETVRELTDWLLSKGEDLQRCSDPSGNS ASIQRKLTDVRDLLAQCVCEGRERLRRVRLSCDRAGRLTAAAGCELMDAEVQALSRALQQ WEGRALNTRDALETAVAAATGAERERERLTEQLEGEMERLEERLKEWSEGLSRSERRNSG TAAVEGWTLAKGVLEGLQAAEVMEEKLKARLNELCGFSTDLGPQSERVSALIKLHNSLSL RASRECQNKEKLLEQRFRSSLRDFRQWLVNANISTAKCFDSPHSIQEASAALQRIQEFMS DREQGQARLDAVLAHGEQLSAVVQADRVEAVRAKTSAASDDWRSLMDNLQQREAILQGLQ SRMQAFEESLQPLQDWLNRTEITVQDSSTRLHDLPAKRLELCKLQSVLEEMCCREPELGG LRERAHSLWEGQAAGKGFVHRVCQLAARYLALSNRTKEKVSRIERVVGEHQLFSQGLQEL QSWVSEAQKILETCRSTTADKSMLVTRMGHLEDLLTARQEREIQLKMLITRGEAVQRNTS AEGVPVVRKQIQDLKDSWDLLFSGTIQCKSQLEGALSHWTSYQEDVSQFEGWLERVEESL GSSDKHYTEMRDKTANLRKAKLLYEEVLSRSSPLDTIATKGSNMTEHSATQQEVHKLNER YEAVKAKAKAAVSKAEELVLVHQEYQRGLHMFEDWLEQEQSSLALLSPLDGDVDTLEKTL KELETLQSSCSQGLTLLKSALASREQVVPWGVPQIEERALETAQREWQEYQERMRDTKTQ VEQTLSRLQQLESCYQSLDQWVEDIERKVRLRSHRRSDSTTKDTQLQQLLQWQMEAGQKQ SEMEGLSALAQQIVEDAHVSARVSTRVTQLTARYHAVLLRIQETVKQLQEEIMSIAEAQS TLRTFSVWQSVAAAEFRTVSESKEALDRTTMEKKMKRLETLQGDMDHGHRLLKTLREKVE QAISFLDDSSASKLEREVQAGRSHLEELILGLRAEHSTTERRILLYKEFQERYKTQQQWL SQTRALLSSSVEPKAELYQRRAQLAKYKAVEQALLSRNSAVSSVLEKGETLLSLLHSPSI KENMDRLQTDYKGLRTAARAQVQKLEGHVKKQEAYHTELQEVERWLLQMSSRMVTPDPAP DGGLEAATQQLARHKAIMEEIAGFEERLAGLKERGEELVSGCSERLQARLRQQTQSHLQG ARDSYSAICSTAQRVYQSLDRELQRHVSLRDTLQQCQTWLSNIQEELQPPVHTPHCLEEV LIQVKQERTLQEQASTYLQLVCSTCDLSDEKVRETAADIQQVKIQVEERMLESQELAENW RTIESLRSDLESRLREAEQLLQNMFRRSAELEPKVAQNQLDQAQDFIQEMQARQADLAHL RESVVKLVTSQESPELLEVGRLRRAWLELGKQAAKLLEQREEDLQRSGDYHECLSTAEEL FDQLSSEWDYLTRGDAEKNTVEYLDALKKLSLDLQDQRCVLDDLRDNRNTILPRLSLEDK DLVKEQVGYLEQRWIHLEMQVQQKIQDTMKTLEDLNHLEDQLRETQEWAEVQRPSVSEVL KTSPPPDLAQSFLFDHLSFCAELEAKQQLLTQVVSEADSLSSHLGLDERRSLQALVQEVQ TLLGSLGAKAAQHRKSLSKVFTERTQFLQALDRATGWIKQQEQRVLADEHIALLPDELSK QVSTCKNICSTLRAYQVELTSLWTQGRELVMNATEEEKTETLQRLEELQGTFESSLQRCT QHLQHLEKALVIRKYFKVDLDRVCEWLREAEAAVFPVIDLSGSDERLQNQLDKYQQLLDQ TSAYENLLLIVQRAGQEILPTLNEVDHCYLDEKLNGLPQQYNNILVSTKEKRERVQRVIV ERREFESLIEVTHKALRQLQEQCDALEEPQTSQSLEGGQRLHSVYSELEKGLANLFQAMK ELRGKTQDFQSMGQPYKPEVVEQLVSLHCRLNRVTKDKVKQLNSTLNTLEDYNAAVLKMD SSMNAIKEKLCSDEHTDAMQRLSSLHKLAKDLEDVASFSETLTGQRKELGQHFESNALKT QVASEKPQLQALKSKISDCINECENSVVESCSFQTEIKVNLRWLKTLREKLRCPLNLQKT NVDLVEDEVRSVLALEDEMKSRLKLLNVLRENEKQKSNTELSSHIEGYLKDIEKLETEVR QALTDKQAALQSALYLLQTYKRSLRTTCQWLGDADTVLKQTSVKSVDLEDLTEYLQETER VIDQEQTFKAGVQDTEALFTQMEAFFDSGVIEELKQDLETTRQRSTKLMEQLRHQQETLT RCSAQWSVFQIESEEFIKQMSEIEKRLEGFSTAKASSLQEAEDKLQCHHTIVLQVEAFQH KLTKLEEHIAQFDETVSGAMVSHSVCAMRCQWTQLNSVARAQEKALKDTVHDWRCFTEKL VKMKTVSEDLHSRVPDSVVEKAASMVALNSLLEYHDSFSREVERESSALTLLKHQALSLL LQPVSAGVHTHSNQSSSPRHRPATPTNLSDTPCNNQSDSPKNQPATPTNLSTTSCNNQSA SPRHQPATPTNLSTTSCNNQSPRHQPATPTNLSTTPCNKPASSCNNQTTSCSNGATSSVH QPVLPSNQMTSPSNQSNMPSIQLHTSSNQTASSCSQSATPCNLLHAPNSQSTSPGNHISK FINAEALCLREIQQMQQTYESLLQQVSVSRQQVQLELLEREEVERELGLVKGWIQDTQGL LLSPTADLDTLLSDLEMAHGGVQSQRQALEQIADRQQMKYKDLHATLPSEISTQLAEVTL ALGSAEDQVQTREREVQHSRDVKEDFNTRLQCISKKVNLITLKLKQKSVDVEEAKEETET LCEELVHCSHALSELDVAVQEFGEQNPLLARQLGVSLSKLTELHSQTSRLAEGKTTRLKK AEQHFEEFNEMLTLVLNWTEKAETLISTNIVWSPASMMQEQIRTHQALLREWRKLQGDME GLVERVGLLGDVVQTEALHQQVAELSHHAEELQQRAKSRLLSLQDAAKDLGRLESEVKSL HQSVERVQETLASPDLARLSLREQLVQRQLLLTEMEGIKVQVQALQTCMSNLQLPEEAMA TLPLCVTAQNLQQDSSHLQHTAIQQCNILQEAMVQYEQYEQEVKNLQKLIEEAHRVIQDR PVATGNIQELQTQIQHHEELAQKIKGYQEQIAALNSKCKMLTVKAKHATMLLTVSEVDGL SDDLEELEEEEVEMSKHPATHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEVSSPPACRS PSPGPNADASLNQVPGRALLSRAPLQELYDPSMESSASANLDDLQRSWETLKNVISEKQK SLYEALERQQHYQEALQSVSTKMESIETSLNEGLEPGKSPESQMAAHQALMDEILMLQDE ISALQACFSEELQRDEESPEQDVGDQLALHSTLTVLGERMATIRMKASGKRQLLEERLSE QLEEQRQEQALQRYHSEAEELDHWLLSTRASLTSALQPNAEDMDMEEQLIDCQNMLMEIE QKVLCLSELSVHSESLLLEGKVGMRGDAEQLTLKLHGLKSSLLELQRILQDKHTHIQGSL LEQEDSEPDSSLSQSPSVMDWLSQARSTRSQQHQDTVQRQRELEAQMEEQRKLVQSVACR GEELLSQRTTPNGESAGDLQDSTEHSESGSAQNHMSVKWDNLSTDLNAKLQLLLNTIQQE QLSLVYQRSRVSSPGGIFRGEQLTQDGLSPRTLFETFSEELEELSKEGGANNKQSQALET TLYEAVSSASVWLDSAENTLLSGPMLLSDDSEIQLCHLECLNKEVKNVSEEVSKCREAMG GDAESMWGGEGDGGGHDLIEEVLDGLEERLRLVDSLLDQRCDSIRDRVQEHVTFQTELRL LFAAMSDSKQQLLQKMSGAVDRPASKQMETLAEAEDGLREFEQRVCEMRGRGETLQQDPV STQELLKLQDVYEELVEMVGSRRSSLNQTLVLKAQYEKALQDLQELVDTAHDKMAADQKM TVGSVLEVQILLDKHKEFFQGLEAHVVLTQAFFRQVSGVVVQREAQALEQTVAQAQTVLK QAHRRGVELEGILEAWSRFVGDYQAVYRQLEAVESSIPSVGLVEETEERLTERIALYQRL KSSLAERQQQLYEVLEDGKKLLLSVCCSELEAQLTQLGEHWLCCSTKVNKELHRLDSTLK HWTSYQSDSAELGQWLASALDRLEFWSTQSVTVPQELETVRDHLHAFLEFSKEVDAKSSL RSSVLSRGNQLLRLKRVDTAALRSHLGQVETQWADLLTRIPVVQEKLHQLQMEKLASRHA ITELMSWISLMENIIQEDQSKIMEAVGSEVVQTYIQKYKGFRIDLSCKQLTVDFVNQSVL QMSSQDVEGKRSDKTDFAERLGAMNRRWQILQGLITEKIQLLEGLLESWLEYENGVQALK TWISMQEEKTKRKPRIEDVASAQNALKDCRELEELLKEKEKELEKVEEKGRVLVQDKKGE ASSVVMETLKGLNQSWINLDQMIGQTKVSLRAVLEQWSLYKRACEEIHGYLMEGRYSISR LHLLTGSPEAVLVQVENLENLQEELDRQESSLKKFGSLTEQLLKDSHPSVADSLNTALSD VNHRWNTLLEQISEQLRNSKSLLQLWQHYKQLHEHNSKDVQRLEERAERLLNSAAHREIT EEEVKTWIRDCSDLLKTHGSVQGTLQQLTEVEEQLRLQVEPSAMATFHTDYLSLNQRLAT VGHGLHRQQSLLEAGMKDYESFTDELDSLSRCPEEAEEVLKVSDPAVSAELFCLQERMDK LKTQMLKLSRLSPDLEHLNGLGYRLPLNDQEMIRLQNLNRTWASCSAHTTERFSKLQAAV LQRQSFLEKCEAWLTFLTQTEEKLAAEISGNYQSLLEQQREHELFQAEMFSRQQILYSII SDGHQLLNQGQVEDRDDFGLKLALLSNQWQGVVRRAQQRRGIIDGLVCQWQRYTELAEKL RHWLKEVQEPEEQQEGGTVTLQQARGILDHIQLKERVLQRQQGSYVLAVEAGRQLLLSAD ARAEALLQSELTDLQERWRSTSIRLDERKKELLSLLKDWEHCEKGIAASHEKLRAFKRKL SLALPDHHEELHNEQIRCKELEGSTEGWTDDVTGLCVLRDALSSNLSSDDLTVLQERLEL LQRQWEETCHQLALRRQQVSEKLNEWAVFNEKNKELCEWLTHMESKVSQNGDITIEEMIE KLRKDYQEEISVAEENKQQLEQMGERLARSSHESKAAEIQYKLSKVNERWQHLLDLIAAR VKKLRETLVAVQQLDKNMSSLRSWLAHIETELSRPIVYETCDTNEIQKKLNQQQDMQRDI EKHSTGVASVLNLCEVLLHDCDACATETECDSIQQATRGLDRRWRNICAVAMERRLKIEE TWRLWQKFLDDYSRFEDWLKASERTAALPNSSGVLYTIAKEELKKFEAFQRQVQECLTQL ELINKQYRRLARENRTDSSCRLRQMVHDGNRRWDTLQRRVTAILRRLKHFISQREEFETA RDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEIELNTMKIGSVFSQGEALMEK SEPLDAAVIEEELDELQRYCREVFGRVERYYRKLTRLPLVDDDCDGSDREFDLDGSGDLS DLQWEESNSLPRSNNSRPPSVNAAPLRANGSGRDTPASVDSIPLEWDHDYDLEPMSHSIS SDKRGRDGEEDEDILCGSTAALTDVVIPESPEAYIKLTENTLRSSSGETARNILDCHSHN TSYIGYMRLMGDCRGSLDAVKRAEGELEEEEDDLSGLKNPENTDTQNAGVIARWELMQAQ SHSSQNSQREDLVLLQQITSDLEAMEAWFNKTENELTELRGKDLSTDIRTIKERIRKLKE LQKEVDAHKSKILSLNLSSVGLLQSDSEESRKLRERLKEMNSRWDRLGKALQQWRGALQE ALMQCQEFHELSHGLLLWLENIDRRRNEIVPISSGLDRHTLRAHYRALEQIQQELVDSEQ RVSVLQDLSVHLLVQAQGSECLEAQERVHVIGNRLRLLLKAVASDLQLLERELRSLGDTQ DLSAWSLADDVETSGSASPVSVVNVPVQQHPLRGKCIVSEAGSSASRPHRRSRGGSACAS SRSGTSGPRGGAAAGRCQSFLLRVLRAALPLQLLLLLIVGLACLVPMTEEDYSCAHANNF ARSFHPMLRYTNGPPPI NT seq 26694 nt NT seq  +upstreamnt  +downstreamnt atggcacacatgtggcaggatttgtctaccaagaggaagaagtctggagcatctctcaac ttggtggctggggtttcacaacacctgcgggatgagcaagaggctgtgcaaaagcgaact tttacaaagtggatcaactcccatttggcaaagagggatcctccgctggtggtgaaggat ctgtatgaggacattaaggatggagtgatgctgctggctctgctggaagtgctgtctgga cacaagctgccatgtgaacagggccgtaagctgaggagaatccactggcttgccaacgtg ggaacggctctgcgcttcctggagggcaggaggtctgtgtatagaggatctccgattaaa ctggttaacatcaacactacagacgttgtggatggcagaccctctattgtgcttggcttg atatggaccatcatattatattttcagatagaggaactcaccagcagtttaccacctcag aaaggccagaatagcagcaactcctcagtggacagctccaatagcacagagacagccagc ccacccgtcaaacgcaagccccgcctctccttccagggtggggccaagagagctctgctc aaatgggttcaacgaacagctactaagagactgggactggatgtgaaggattttggtccc agctggcgctctggcgtggcgttccatgccgtcatcttcgctctgcggccacaactggtc aacatggagcgcgtgtggaacagaccaaacagagccaacctggaggaggccttctccctg gcagagagagagctgggaataccacgcctactggaccctgaagatgtggatgttgataag ccagatgaaaagtccatcatgacatatgtggctcagttcctcaagcaccatcctgatggc ggggaagcagagtcagttggccagcaagaggagagagagcagcgtaaggttctgagggag ctgaaggtctgggctgatcagctggagaaagactgtgctcaggctcagatggacaaagga gaccctggtcatcagtacaagtcctttaagcagtaccgtgttcagtatgagctgaagaga cgacaggtgctgtccagtcttcagtccactcagagggatggtattcttacctcagatcag gcactgtttaaacaggcctgggagagaatatctactaggctcctggactggcacatacag ttggacagtgctttgccaaacccactgggtgcagtgggaatctggctgcatcaggctgag aaaattctccaagaggagccgcttccccagcaaagccacgagcagaccgctaatgccatc caccaaacactgcagcagcatcaggagatcctggggctctttgaaacacaccagcagact ttccagcagctccacagagacagaagtgtcagtggtgttcctgtaccagcagagcagctc caggacatggcagagagattaaactacatatctacctcctcgcatgttcatttgagcaaa ctggaattctgggagctcaagtaccgtatgctggctctcctgacactgggggaatccaag ctgaaatcctggatagtcaaatacggccgactggagaccacacagcttctgctgcagagc tacgtgtcctttgttgaaggccagcagttctttcagaagtatgagtccctctatgaagac ctgaagcaggctgctgtgctttacacaaatgcagacagctccgctgaagaagctgtgagg aggtttctgagggacatggctgatcagtggaggagtctggcggtggagatccgcagtgtg aggtccatgctgaaggaggtggaggggaactgggagaaatacagcagtgctgtgtcctct ctacaggcctggctggaggatgctcaggttgcattgcaccagcctgaaaacaccaaacga gagttcttcaggaatcttccacactggatggatcaacacacaaccatgaacgattcagga aacttcctcatagagacgtgtgatgagactgtgtcccgcgatctaaagcaccagctgctg ctccttaatggaagatggagagacatgttcattaaagccaaacagtatgcttgtatgcat gagactcagattcagacagagaaggagcagcaggaggccatcgctgctctcaaagacttc atacagacttctacagccaaacttacctcacctgtccagctgtcactaccggatgtggga agctttgtagaggatgttgaggccatcattcacagacttccagcagtggaggtccagtat aagacagctgcccgctctgctcagctccgggccagagacacggtcaatggagatcgaaga caaacattgactacaatggcatctattaaaggacagctctacaagatgaaggagaaatgt ccagtggttctaagagagtgtcagactgtgattcctttgctggaggaactggagagacaa atctcagccttctatcagactgcagagcgtgccggccacatcatcacacagcagcacgac cagcacaagaaccgggagttgctgtctcagcagcagagctgtcagcggtgtgtgtgtgta gtagagcgtagttacctggcacttcagagggcgctgtgctgcactaagactctctacaac ttcgacccgtctctgctgcagaacagagtaaccgagcttcagaccacagctcaggtgctg atgcaggaagctctggagtggaggagagttgctgagaccaatggtaacctgacccggcgc tttgaggagtcccgagctgagctggaaaaggccctgcgggtggggcaggcatgtctgaag gagagaggagacccagctgaactcttaagcaaacataacgattttttcggaaggctggac cagcgagtcttaaatgcatacctgaaggcatgtgatgatctgacagatatcttgccagaa gaggaacagcagggtctgcaggagtcagttaggagactgcacaaacagtggaaggatatc caggctgaagcaccagcgcacctgttgaggctgaaggtggaggcggagcgccgcattgtg ctggcatcactgcaggagtgtaggatagagctgcagaaagaagataaggccattgccaca tctggcagcgagagagtaatcagagagcacagggtctatttcagacagaaagaccccctc gctgtatgtgagaggagactgaagaccatggaacagctgtgccagaaacttccagaaaat gacccaatgcaaagagctctactggagaccaaagatcacctgttagaggtcagagatgaa gtggaaagaacttatgtgagattccagcagcatccagacaagtggagggagtggcatgca aggtttaaggagctctctggctggctctcgtcccagcaggacaagcagaggagtggagag tgctgcactgtgcagcatggtgtgctgaagggtcacgtggacgctttggactggctgaaa actcggctgtctgtactggaggatgtgagcactgaagctgaggttctcactcagacaaca gctctggaagatctctctattcagttcaactttcatgtctcctctctggaagaagacatg tctgtaaacggccacagtgagagcgggcaggaggagctgcagcaggaggaggggctgccg cagccgcaggagcacagcagaatcctaaatgcagagagtgcagcagaggccagacagctg ctcctcattcaccagcagaggctgaaatctcagcagaggaaaaagcacgctgagccgcag ggcctctgcactcgttcttatggtgcactgatggacagggaggaggagcacagctgggca actcaggaggaacttttgcagagcattgtgcgtgcatggcaggactttgagcaggacaga gaggcagtggggcagtttgtttgcagtgccacccctatcctgcagagagagcgcatcttc agcagcctggaaaatctcactactgaacttgatcatgctcaggagcttcacaggaagaca ggtgtgatcacagagcaggccaagtcgctagtgaaaaaagcagctgagatccaactgggc gcccagaatcattctcttctgcatgaccaggctcaggctgctcaagagcgagtacaagag atacacatcagcctggagaaaatgataatgggtcttgagaagatgcaggtgagatggcag aattttaacagtgagtcagaagctttctcctcctgggtgtgtgagagagagaaggagctg gaggctctggacctgaactctgctcacttggatcagcagcttcagactgtggaggcaatg gaagcaggtctagaggagagaatgaaggtcctgagccagctggagtctgagtctcatgct ttggctcgtttcatcacaccagggggggcggagcgcattaaagctcgattaatacagatt ggcaggtactgggaggagcttaggagcaacgtcaagcagcgagggatggagcttcaggcc agtgttttacataaagtgaagttaaatgaagatctagaggaggtaataaatgcagtgaaa gcgcttgaggacaagttgaacaagccaattgcatcctgcttctcatcttcagcaacatac caaactctgcatgatcatatggatgtctggcaagctctgaagcagctgcagcccaggctg gtgtcactgagcctgggcttgagaaggctttgtgatgggggtcaggtggagaaagcggtg gcagacctccagcatgcacatacagagtgcacacagaaagctgccagcaagcaagccatg ttggaagatctgctttctctgtggcagaaatatgaaagagatctctcagttcttcagggc tggctggacaggtgtgagtttctctgtacctctgaaaagctatacctgaccacggataag tccaagcttcaaagtcagcttcagatgctgcaggacctgcagtctgaggtaccctctcag gagtctttgttggagaagctggagaaccaggcggagtctctgtaccccacggcctcagag gaacgagtgggagaactcacagagctccactgcagcctggaggaaagatggtgctctctc agtacaaacatccctctcaggattcaagaacttcaggcccatcttgctcagctggagcag tttaatcaggcactggtaaccttcactctgtggagtgaaaacttccttggggagctgaga agaaaatctaaagtgaccatttctgatttgatatccgttaaaacccaaatcaaggaggat gaggctcttctccaaacccagagggaggcaatagatgggctgcagcagcacatggatgct cttggtccctctttatctcctgaggacctccagcggctgcaggtcaggaaggaggactgt ctgcagcctgtctgtgaggctcagagtctgctgcagcgccggagtgaagccctgggtaaa cttgagactttcctggtgacctacagatcagccaccaactcagtacagacccaccagggg gctgttgaaggcagaggcagttgggaccaggccaaggctgagcagctcaaccaggatctt ggacagctggcccagaagttagcctctctggaggtgcaggctataagtttggacagcagc ctaaacaaagcatctctgcacctgcacagggccgagggagagagaacgtcctgtcggcgg ctggtggacgagcagggatcaggcctgcagaggctccagaggagcctggggacgaggcag agcgaggcagagacactggcaggtctgtggaactcctttagggggagaaaagagctgctg ctgaggagtctcatggagctggaggagaaagtcaggaagacgtggcttacagaacccagc acacagaactttcagcagaggctgtggatgctggaccagctagaggaggagctccaggcc ttgcagcacagtcagctctggttaggggagagaggagagcagctttcccacagagacagt gagatgagtgaggaggtccagcaggatgtaaccctggttcagtccacctgggagaggata cagagactcatcactgaggagcaggagcagtgtgcagtcttgctggacgtctgtaaagat tactttactctaaagtccagaattacctctgctgttgagagagctcacgctgtcactgca gcacagtccggccaacacaaccctgaggacattcggagggccttgtcccggctggaggca gtgaagccggagttggcaggcacacaggaggaactgaatctgttcatcagtaaaggcaaa cacctcatcagtgagctgaggaagcttccagaacacacaggagagagtgtccgcacagag 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tcaagtcagctggcattagatgggtttgtggtggcatgcagacagagactgcgctctatt gaggagagtgctgcgctccaagacgggtttgaggtccgtgtggatgagttgagagcctgg ctgcagcagattgcggcgaagctgcagggagaacctgctctttggggagaaagcaagcaa ggatcctctgactgctctgcacagctggagagaatggaggagcttcacaaagagctgctg atgaggaggccatctctggagcgttcatgccaggcctttctgaccctgtctgatggtcga gctggagaccctgaggcctctcaaaccatggagctgctttcctcccatcaggcactggtg caggaagcctgggtgcggctccgcggcctgcaggaataccaggccttcaatgaggcactc agagccatgggggactggctggaggaagtggaagaaaagctggagaagctagagagtaca gagggggacaaaaaagaggtggaggagagactggagagagtgcaggatatcctgttgatg aagggtgagggcgaggtgaaactcaacatggctgccgggaagggggaactggtcatcaag agcagcggggaagctggacaggatgtgatccattttaaactgcaggaagtagaggatgcc tgggcggcactgcttttgagggccatgagttgccacagccgtttggagtggaccgtgagc cagtggggcctgtttgtggagtcccgtgcacagctgcagggctggctggagcaggtggag gcggaagtgaaaggcccactggagcctcagctgggtctgagggagaagaggcagcagctg gaccgtctgtgcttactctcggctgatgtggaagaccatcagggggcgctgtgctatttg gaggagagtgcggctgagctgtacaagcgcactggagatgctacctttagggaggatgag acggctctcctcagggctcagtttgacgatgtccgagctgccacagaggagagggtcaga ttttcagaatgtgttgtttttgaacatgagaagtatatggagacagtgagagagctcact gattggctgctgtccaaaggggaggatctccagcgctgttccgatccatctggtaactct gcgtccattcagcggaagctcacagacgttcgggatctgttggctcagtgtgtgtgtgag ggtcgtgagcggttgaggcgcgtgcggctgagctgtgaccgggccggccggctgacggcg gctgcgggctgtgagctgatggacgcggaggtgcaggctctgtcccgcgcgctgcagcag tgggagggacgggcgctcaacacgcgcgatgcgctcgagaccgcggtggctgcggcgacc ggagccgagagggagcgcgagcgcctcaccgagcagctggagggagagatggagcgactg gaggagcggctgaaggagtggagcgagggactaagtcgctcagagaggaggaacagcgga acagccgcagtggagggatggacactggcgaagggtgttctggaaggcctgcaagcggct gaagtaatggaggagaagctgaaggctcggctcaatgagctgtgtggattctctactgat ctgggccctcaatcagagcgtgtcagtgctcttatcaaactacacaacagtctcagtctg cgggcctccagagaatgtcaaaacaaggagaagctcctggagcagcgtttccgctcctcg ctgcgggacttccgtcagtggctggtcaacgccaacatctccaccgccaagtgcttcgac tcaccacacagcattcaggaggcctccgccgccctccagaggattcaggagttcatgagt gacagggagcagggccaggccagattagacgcagtactggcccacggggagcagctcagc gccgtggtgcaggctgaccgggtggaggcggtcagggccaagaccagtgctgccagcgat gactggaggagcctgatggacaacctgcagcagagagaggccatactacagggtctgcag tctcgcatgcaggcgtttgaggaaagcctgcagcctcttcaggactggttaaacagaaca gagatcacagtgcaagatagcagcactcgcctacatgaccttcctgccaagagactggag ctgtgcaaactacagtccgtgctggaggagatgtgctgtagggagccagagctgggaggg ctgagggagagagctcatagcctgtgggagggtcaggctgctgggaagggatttgtgcac cgggtctgccagctagcagcacgctacctggccctcagcaaccggactaaggagaaagtg tcaaggatagagcgtgtagtgggggaacaccagctcttctcccagggtttacaggagctt cagagctgggtttcagaggcacagaagatccttgagacatgccggtccaccacagccgat aagagcatgctggtcaccagaatgggccatctggaggatctgttaacggctcgtcaggag agagagattcagctgaagatgctcatcaccagaggagaagcggtccagaggaacacgtct gcggagggagtacctgtggtgcgcaaacagattcaggaccttaaagattcttgggattta ctcttctcaggaaccattcagtgcaaaagccagttggaaggtgccttgtcccactggacc agctatcaggaagacgtgagccagtttgagggctggttggagcgagtggaggagagtttg gggagctcagataaacactacaccgagatgagggacaaaactgccaacttgcgaaaggct aagctgctttatgaggaagtattgagtcgctccagccctctggacacaatcgccacaaag ggctccaacatgacggagcactcagccacccaacaggaagtacacaaactcaatgagcga tatgaagccgtcaaggccaaagccaaggctgcagtcagcaaggcagaagagctggtattg gtccaccaggaataccagcggggactccacatgtttgaggactggctggaacaagagcaa agcagtctggctcttctttctcctctagatggagatgtggacactctggagaagactctg aaagagttggaaacgctgcagtcaagttgttcacaaggtctaaccctactgaagtctgcg ctggccagtcgtgagcaggtcgtgccctggggcgtcccgcagattgaggagcgggctctg gagaccgcacagagagagtggcaggagtatcaggagaggatgagggacacaaagacccag gtagagcagaccctcagcagactccagcagctagagagctgctaccagagcttggaccag tgggtggaagacattgagcgcaaagtgaggctgaggagccacaggcgctcagattccact acaaaggacacacagctgcagcagctgctgcaatggcagatggaagctggacagaagcag tcagagatggagggtctcagtgctctagcacagcaaattgtggaggacgcccatgtcagc gccagggtcagcaccagggtcactcagctgactgcacgctaccatgcagtgctactgcgc atacaggagactgtcaaacagctccaagaggaaatcatgagcattgcggaggctcagagc accctcaggaccttctctgtgtggcagagcgtagcagcagcggagtttagaaccgtcagc gaaagcaaggaagccctggaccgtaccacaatggagaaaaagatgaagcggttggagact ctacagggagacatggatcatggccaccgtctactgaagacactacgcgagaaggttgag caagccatctcgtttctagatgacagcagtgcctctaagctggagagagaggtgcaggct ggccgatctcatctggaggagctgatcctgggtctaagagctgagcacagtaccacagag agacgcatcctgctgtataaagagttccaggaacgatacaagacccaacagcagtggctg agccagactagagctctgctcagctcgtctgtggaacccaaagctgaactctaccagaga agagcgcagctcgctaaatacaaggctgtggagcaggctctgttgtctcgtaattctgca gtaagctcagtgctagagaaaggagaaacgctgctgtctctcctgcactctccctcaata aaagagaacatggacagactgcagaccgactacaaggggctgcgcacagctgccagggct caggtacagaagttggaggggcacgtgaagaagcaggaagcttatcacactgagctgcag gaagttgagcgatggctactgcagatgtccagcaggatggtgacaccagaccctgctcca gacggggggctagaagcagccactcagcaattggccagacacaaggccatcatggaggag atcgcaggctttgaggagcgtctggcggggctgaaggagagaggagaggagctggtgtct ggctgcagtgagcgcctccaggctcgccttcgccagcagactcaaagccacctgcaggga gctcgagacagctactccgccatctgcagcacagcacagcgcgtgtatcagagtctggat cgggagctgcagaggcatgttagtctgcgagatacgctgcagcagtgtcagacttggctt tccaacatacaggaggaattacagccccctgtgcacacgccacactgcctggaggaggtg ctgatacaggtgaagcaggagcgaactctgcaggagcaggccagtacttacctgcagctg gtgtgttccacttgtgacctgtctgatgaaaaggtcagagagacagctgctgatatccag caggttaaaatccaggttgaagaaaggatgctggaatctcaagagttggcagagaactgg aggacaatcgaaagtctgcgctctgatctggaatctcgcctcagagaggctgagcagctc cttcagaacatgtttaggagatcagcagaactagagccaaaggttgctcagaatcaactg gaccaggcccaggattttatccaggagatgcaggcgagacaggctgatcttgcccatctg agagagagtgttgttaagctggtgaccagtcaggagtcccccgagctgctggaagtgggt cgtctgcgtcgggcttggctggagctgggaaagcaggctgcgaagcttttagagcagaga gaggaggatctccagagaagtggagattatcatgagtgcctcagtacagcagaggagctg ttcgaccaattgtccagtgaatgggattacctgaccaggggagacgcagaaaagaacact gtggagtatttggatgccttaaagaagctatctctagatcttcaggaccagagatgtgtg ctagatgatttgagagataacaggaacaccattctgcctcgcctcagtcttgaggataaa gatcttgtaaaagaacaggtggggtatttggagcaacgctggatccatttagaaatgcag gttcagcagaagattcaagacacgatgaaaaccctcgaggacctgaaccatttagaggac cagctacgggagacccaagagtgggctgaagttcagcgaccgtctgtctcagaggtgctg aaaacaagtcccccaccggatttggctcagagctttttgtttgaccacttgagcttttgc gcagaactggaggccaagcagcagcttctgactcaagtcgtgtctgaagctgacagcctt tcatcccatcttggtctagatgagagaaggtcactgcaggctttggtgcaggaagtgcag acactgcttggatctcttggagctaaggcagctcagcaccgcaaaagccttagtaaggtg ttcacagaacggacgcagttcctccaggctctggacagggcgaccggatggatcaagcag caagagcagagggttctggcagatgaacatatagcactgttaccagatgagctctccaag caagtgtcaacttgcaagaacatatgtagcactctaagagcataccaagtggaactgacc tcactttggacacaaggacgggagttggtgatgaacgcaacagaggaggagaagacagag acacttcagaggcttgaggaactgcagggaacctttgagagttccctccaaagatgcacg cagcacttgcagcacctggagaaagcactggttattcggaagtattttaaagtagacctg gaccgagtctgcgagtggttgagagaggctgaagcagccgtgttccctgtaattgactta agtggaagtgatgaacgactgcagaaccagttagataagtaccagcagcttctggaccaa acctcagcgtatgaaaacctcctgctgattgtccagagggcaggacaggaaattctgccc acactaaatgaggtggatcactgttacctggatgagaaactgaatggccttccgcaacaa tacaataatattcttgtatcaaccaaagagaagagagaaagggtgcagcgcgtgattgtg gagcgcagagaattcgaatctctgatagaagtgacacacaaggctttgaggcagcttcag gagcaatgtgatgccttagaggagccacaaaccagccaaagtctcgagggtggacaaaga ctgcatagtgtttattcagaactggaaaaagggcttgcgaatctttttcaagcaatgaag gagttaaggggtaaaactcaggatttccaaagcatggggcagccatataaacctgaggtc gtcgagcagctagtgagtctacactgtagactcaatcgagtgacaaaggacaaagttaag cagctaaacagcactctgaatacattagaagactacaacgctgcagttctcaaaatggac agcagcatgaatgcgatcaaagagaaactttgttctgatgaacacacagatgccatgcag agattatccagtttacacaaactggccaaagatctagaggacgttgcttctttttcagaa acgttgactggacagagaaaggaactcggccagcactttgagtccaatgctcttaagact caggtagcctctgagaagccacagcttcaggccttgaaatcaaagatttctgattgcata aatgaatgtgagaactctgtggtggaaagttgtagttttcaaactgaaatcaaagtaaac ttaaggtggctcaaaaccctcagagagaaactcagatgcccattaaatctccagaaaaca aatgtggacttggtggaagatgaagtccggtcagtactggctctcgaagatgaaatgaag tctaggttaaagttattgaacgttttacgagaaaatgagaaacaaaagagcaacacagaa ctgtcgagccatattgagggttatttgaaggacattgagaagttggagactgaagtccgg caagcactcacggataaacaggcagctttacagtcagcactttatttgctgcaaacgtac aagcgttccttgaggactacctgccagtggttaggggatgctgatactgtcctaaagcag accagcgtaaaatctgtagatttagaggaccttacagaatatcttcaagaaacggaacga gtgatagatcaagaacagacctttaaggctggagtgcaggacactgaggctctgttcact cagatggaggccttttttgattctggtgttattgaggaactaaaacaggacctggagaca actcgtcaaagaagcacaaaactcatggaacagctgagacatcaacaggaaactttgact agatgctctgctcagtggagcgtgttccaaatcgagagcgaagagttcataaagcaaatg agtgagatcgagaaaagactggaaggttttagcactgctaaagctagctcgcttcaggag gcagaggataaactccagtgtcatcatactattgtgttgcaggtggaagcttttcagcac aaactgacaaagctagaggagcacatcgctcagtttgatgagactgtgtctggtgccatg gtttcccattcagtctgtgccatgcgctgtcaatggactcagctgaacagtgtagctaga gcacaggagaaagctctcaaggacactgtacatgactggaggtgttttacggaaaagctg gtgaagatgaagaccgtgtctgaggatctgcacagccgagttcctgacagcgtggtggag aaagcagccagtatggtcgccttaaacagtctgttggagtaccacgactctttcagtcga gaggtggagagagagagcagtgccctgaccctcctcaaacaccaagccctcagtctcctc cttcaacctgtcagcgcaggagtccacacccacagtaaccaatcgtcctcacctaggcat cgaccggccacacctaccaacctgtcagacacaccctgcaacaaccaatcagactcgccc aaaaatcaaccggccacacctaccaacctgtcaaccacatcctgcaacaaccaatcagcc tcacccagacatcaaccagccacacctaccaacctgtcaaccacatcctgcaacaaccaa tcacccagacatcaaccggccacacctaccaacctgtcaaccacaccctgcaacaagccg gcttcatcctgcaacaaccagacaacctcatgcagcaacggagcaacctcatcagtccac caaccagtcttaccaagcaaccagatgacctcacccagcaaccaatcaaatatgcctagc atccagttacatacttccagcaaccagacagcctcatcttgtagccaatcagccactcct tgcaacctgttacatgctcctaatagccaatcaacctcacctggcaaccacataagcaaa ttcatcaatgcagaggcgctctgcctgcgggagattcagcaaatgcaacaaacgtatgag agtctgttacagcaggtgtctgtgagccggcagcaggtgcagttggagctgctggaacga gaggaagtggagagggagctggggctggtgaaaggctggatccaggacactcagggtctg ctgctcagccccacagcagacctggacaccctgctgtctgacctggagatggctcatggt ggcgtgcagtctcagcggcaagccttggagcagattgcagaccgccagcaaatgaagtac aaagacctccatgctactctgccctctgaaattagcacgcaattagcagaggttactctg gcactgggttcggctgaggatcaggtgcagaccagggagagagaggtccagcacagcagg gatgttaaagaagactttaacaccaggcttcagtgcatctctaaaaaagtcaatcttatc actttgaaactgaagcagaagtctgtggatgtagaagaggcaaaggaagagactgagacc ctctgtgaggagctggtgcactgctctcacgctctgtctgagctggatgtggctgtgcag gagtttggggagcagaacccactgctggccagacagttgggtgtcagtcttagcaagctg acagaactccactctcagaccagccgactcgctgagggaaaaactactcgtctgaagaag gcagagcagcactttgaggagtttaatgagatgctgaccttagtcctgaactggacagaa aaagcagagactcttatctcaaccaacattgtctggagccctgcctcaatgatgcaggaa caaatcagaacccatcaggcattgctgagggaatggaggaagctccagggcgatatggag ggcctggtggagagagtggggctgctcggggacgtggtgcagactgaagctcttcaccag caggtggcagagctgagccatcatgctgaagagctgcagcagcgggccaaatcccgcttg ctgagtctacaggatgctgccaaggatctgggcaggttggagagtgaggtgaagagcctt catcagtctgtagagagagtgcaggagaccctggcttcacctgacctcgcccgcctcagc cttcgggaacagctggtccaaagacagctcctactgacagaaatggagggtattaaagtg caggtgcaggctctgcagacctgtatgagcaaccttcagcttccagaggaggcaatggca accttacccctgtgcgtcactgcccagaatctacagcaagacagcagccatcttcagcac actgccatacagcagtgtaatatactccaggaggccatggtgcagtatgaacaatatgaa caggaagtgaagaatctacagaagctgatcgaagaagctcatcgcgttattcaggaccgc cctgttgctacgggcaacatacaggaacttcagacgcagatacagcatcatgaggagctg gcccagaagataaaaggctaccaggagcagatagccgccctcaactccaagtgcaagatg ctgacagtgaaagccaagcatgcaaccatgctcctgacggtcagcgaggtggacggactc tcggatgacctggaggagctggaggaggaggaggtggagatgtccaaacacccggcaaca cacccctctgtggtcatgatgactgcgggccgctgtcataccctgctctccccggtaacg gaagagtctggtgaagagggcaccaacagtgaggtatcctctcctccggcctgccgctcc ccttcccctgggcctaatgctgacgcatcccttaaccaggttcctggaagagccctatta agcagggctcctttacaggagctttatgatccctccatggagtccagtgcctcagctaac ctggacgacttgcagcgctcatgggaaactctgaagaatgtgatcagtgaaaagcagaag agtctgtacgaggctctggagagacagcagcactaccaagaggccctccagtccgtctcc accaagatggagtctatcgagacctcgctcaacgagggcttagaacctggcaagagcccc gagagccagatggcggctcaccaggccctgatggacgagatcctgatgctgcaggatgag atcagtgctctgcaggcctgcttctctgaagagctgcagcgggatgaagagagtccagag caggacgtgggagaccagctggccctgcactccactctcacagtactgggggaacgcatg gccaccatccgaatgaaagcctctggcaaacgtcagctgctggaggagcgtctgagtgag cagctagaagaacagagacaggaacaggccctgcagcgttaccacagtgaagcagaggag ctcgaccattggctgctgagcactcgggcctcacttacctctgcactacagccaaatgca gaggatatggacatggaggaacagctcattgactgtcagaacatgctgatggagatcgag cagaaggtgctgtgtctgtctgagctgtcggtgcacagcgagagtctgctgctggaaggg aaagtcggcatgcggggagacgccgaacagctcaccctcaaactgcacggcctcaaatcc agcctgctggagctgcagcgcatcctgcaggacaagcacacacacatacagggttcattg ctggagcaggaggacagtgagccggactcatcgctctcccagagccccagtgtgatggac tggctcagtcaggcccgctctacccgcagccagcagcaccaggacactgtgcagaggcag agggaattggaggcccagatggaggagcagagaaagttggtgcagtccgtcgcatgccga ggggaggagcttctgtcacagagaaccacacccaatggagaaagtgctggagacctgcag gactcgacagagcattctgagagtgggagcgcacagaaccacatgagtgtgaagtgggac aacctgagcacagacctgaacgccaagctgcagcttttactcaacaccatacaacaggaa cagcttagcttggtttaccagcgatcaagagtgtcaagcccagggggtattttcagagga gagcaattaacgcaggacggcctctcgccaagaacgctatttgagacttttagtgaagaa ctggaggaactttccaaggaagggggagctaacaataaacagagccaggctttggagact actctctatgaggctgtttcttcagcttcagtctggctggacagtgcagaaaacacactg ctgtccggacccatgcttctgtctgacgattcagagattcagctctgccatctagagtgt ttgaataaggaggtgaagaacgttagtgaggaggtgtctaaatgtcgggaggcgatggga ggagatgctgagagcatgtggggtggagaaggagatggaggaggtcatgacttgattgag gaggtgctggatgggttggaggaaagactgagattggtggattcattgctggatcagaga tgtgacagtattcgggacagagtgcaggaacacgtcactttccagactgaactgaggttg ttatttgctgctatgagtgactcaaaacagcagctgctgcagaagatgtctggagctgtg gaccgcccagcctcaaaacagatggagactctggcagaagctgaagacggtctgagagaa tttgagcagagagtttgtgagatgagaggtagaggagaaacactgcagcaagaccctgtt tccacacaggagctgcttaaactgcaggatgtgtatgaggagctggttgagatggtaggc tcgcggcgcagcagtctgaaccagaccctggttttaaaggcacagtatgagaaagccctg caggacctgcaggaattagttgacacagcccatgacaagatggctgctgatcagaagatg accgtaggttcagtcctggaggttcagatactcctggataagcataaggagtttttccag ggcctggaggctcatgtggtgctgacccaggctttctttaggcaggtcagtggggtggtg gtacagagagaggcgcaggctttggagcagactgtagctcaggctcagactgtgctcaaa caggcccacaggagaggagtggagctagaaggaatccttgaggcatggagcaggtttgtg ggagattatcaggctgtttacagacaactggaggcagtggagagcagcattcccagtgtg ggactggtggaggagacagaggaacgactcacggaaagaattgcactttaccagcgtctg aagagcagtcttgcagagcggcagcagcagctgtatgaggttttggaggatgggaagaag ctgttgctcagtgtttgttgctcagagctggaggcccagctcactcagctgggagagcac tggctctgctgcagcaccaaagtcaataaagagctgcatcgcctggactccaccctcaaa cactggaccagctatcagagtgattctgcagagctgggtcagtggctggcttcagcttta gaccgacttgagttttggagcactcagtctgttactgtccctcaggaattggagactgtc cgagaccacctccatgcttttctggaattctctaaagaggttgatgccaaatcgtccctg cgctcgtctgttctgagtcgaggcaaccagctgctcagactaaagagggtggacacagca gccctcagatctcacttgggccaggtggaaacacagtgggctgatctgcttacacgcatt cctgtcgtacaggagaagcttcaccagctgcagatggagaagctagcatctcgccacgca attacagagctaatgagctggatttctctcatggaaaacatcatacaggaggaccagagc aagatcatggaggctgtgggttcagaggtggtgcagacatacatccaaaaatacaaggga tttcggattgacttgtcctgtaagcagttgacagtggattttgtgaaccagtcagtgctt cagatgagcagtcaggatgtggaaggaaagcgcagtgataagacggactttgctgaacgg ttgggagccatgaaccggcgctggcagatactgcaggggctcattactgaaaagatccag ctgttggaaggtcttcttgagagctggttggaatatgaaaatggagtgcaggcactaaaa acgtggattagtatgcaggaggaaaagactaagaggaaaccaagaatagaggatgtagcg tcagctcagaatgcactgaaagattgtcgggagttggaggaattgttgaaggagaaggag aaggagctggagaaagtggaggaaaaaggacgtgtgctcgtccaggacaagaaaggagaa gcctcatcggttgttatggaaaccttgaaaggacttaaccagtcttggatcaatttggac caaatgatcggccagactaaagtgagtttgcgggcggtgctagaacagtggagcttgtat aagcgggcgtgtgaagaaattcatggttatctgatggaaggccgctactccatctcccgc ctccatctccttaccggctctccagaagctgtgcttgtacaagtggagaatctggagaat ctccaagaggagctggacaggcaggagagcagtctgaagaagtttggctctctcactgag cagttgctgaaagacagtcacccctctgtggccgactccctgaacacagccctcagcgat gtcaaccacagatggaacacactgctggagcagatctcagaacagctgaggaacagtaag agtctgctgcagctctggcagcactacaagcagcttcatgaacacaacagcaaagacgtt cagaggctggaggagagggcagagcgcttactcaacagtgccgcccacagggagatcaca gaggaggaggtgaagacctggatccgtgactgcagtgacttgctgaaaactcatggctca gtccagggaaccctgcagcagctgaccgaggtcgaagaacagctgaggctgcaggtcgag ccatcagcaatggccactttccacacagactacctgtcactcaatcagcgcctagcaaca gttggtcatggacttcacagacagcagtctttgctggaagctggcatgaaggactatgag agcttcacagatgagttggactctctaagccggtgtccagaggaggcagaagaggttctg aaggtgtcagatccagcagtatcagcagagctgttctgtctgcaagaacgcatggataaa ctcaagacccagatgctgaaactgagccgcctgtcgcctgatctggagcatttgaatggc ctagggtacagacttcctctaaatgatcaggagatgatacggctccagaacctgaacagg acctgggcctcgtgttctgcacacaccacagagaggttcagtaagctgcaggccgcggtg ctgcagaggcagagcttcctggagaagtgtgaggcgtggctgacctttctcacacagaca gaggaaaagctggctgctgaaatctcaggaaattaccagagcttgttggagcagcagaga gagcatgagctgttccaggcagagatgttcagtcggcagcagattctttattccattatc agtgacggccatcagctgctaaatcaggggcaagtggaagacagagatgactttgggctg aaattggcattgctgagtaaccagtggcagggagtggtgcgacgagctcagcagagacgg ggtataattgacggtttggtgtgtcagtggcagcgctacactgagctggcggagaagctt aggcactggctgaaggaggttcaggagcctgaagagcagcaggagggaggaactgtgact ctgcagcaggctagaggaatactcgaccacatacagctgaaggaacgggtgctgcagagg cagcagggcagctatgtcctggcagtggaggcaggaaggcaactgcttctgtctgctgat gctcgtgctgaagccctgctgcagtctgagctcacagacctgcaggaacgctggaggagc accagcatccgtctggatgagaggaaaaaagagcttctctccctgttaaaggactgggag cactgtgagaaaggaattgctgcgtcacatgagaagctcagggcattcaagagaaagctc tctctggccttacctgatcaccatgaggagctgcacaacgagcagatccgctgcaaggag ttagagggcagtacagaaggctggactgatgatgtgaccggcctgtgtgtgctcagagat gctctctccagcaacctgagctctgatgatcttacagttctacaggagagactggaactg ctgcagagacagtgggaggagacatgccaccagctggctctgcgtaggcagcaggtgagt gagaagctaaacgagtgggctgtgttcaatgagaagaataaggagctgtgtgagtggctc acacacatggagagcaaagtctcccagaatggagacatcaccatcgaggagatgatcgag aaactcagaaaggactatcaggaggagatttctgtggccgaggagaataagcagcagctg gagcagatgggggagagactggcccggtccagccatgagagcaaggctgcagagatccag tacaaactcagcaaagtcaacgagcgctggcagcacctgctcgacctcatcgcagccagg gtgaagaagctgagggagaccctggtggctgtgcagcagttggataaaaacatgagcagt ctgcgctcatggctggctcacatcgagactgagctctctcgacccatagtgtacgagacc tgcgacacgaacgagatccagaagaaactcaaccagcagcaggatatgcagagggacatt gagaagcacagcactggtgtggcatctgtgttaaacctgtgtgaggttctactacacgac tgtgatgcctgtgccacagagacagagtgtgactccatccagcaggccacacgaggcctg gaccgccgctggaggaacatctgcgctgtggccatggagaggaggctcaaaattgaggag acatggagattgtggcagaagttcctggatgattattcccgctttgaagactggctgaag gcatccgagaggacagcagctctgcccaactcttcaggcgttctctacaccattgccaaa gaggagctcaagaagtttgaggcgttccagaggcaggttcaggagtgtttgactcagctg gagctaatcaacaagcagtaccggcggctggcccgcgagaaccgcacagactcttcctgc cgactacgccaaatggtgcatgatgggaaccgacgctgggacaccctgcagagaagggtt acggccatcctgcgtaggctaaagcacttcattagccagcgtgaggagtttgagacagcc agagacagcattctggtgtggctgactgaaatggatctgcaacttaccaacatagagcac ttctcagagtgtgacgtccaggctaagatcaaacagctgaaggcattccagcaggagatt gagctgaacacaatgaagatcgggagtgtgttcagccagggtgaggctctgatggagaag agtgagcctctggatgctgctgttatagaagaggagctggatgagctgcagagatactgc agggaggtgtttggccgcgttgaacgctactacaggaaactcacacgtctgccgctggtc gatgatgattgtgacggttcagatcgggagtttgacctggacggctcaggtgatctttct gatctccagtgggaagagagcaactccttgccgcgctccaacaacagcagaccaccttca gttaatgcagctcctctacgtgccaatggctctggccgagacactccagccagcgtggac tccattcccctggagtgggaccacgactacgacctggagcccatgagtcattccatctca tctgataagagggggagggatggagaagaggatgaagatatcctctgtggttccactgca gctcttacagacgtagtgattcctgagagccccgaggcttatataaaactgactgaaaac acactgaggtcttcctctggtgaaacagctcgcaatatcctggactgccacagtcacaac acctcatacattggttatatgcggttgatgggagactgccggggcagtctagatgctgtg aaaagagcagagggagagctggaggaggaagaggatgacctgtctggactcaaaaaccca gaaaacacagacacacaaaacgcaggtgtgattgcacgctgggagctgatgcaggctcag tcacacagctctcaaaacagccagagagaagacctagtactcctgcaacagatcacctct gacctggaggctatggaggcgtggtttaacaagacagagaacgagctgaccgagctgagg gggaaggacctgagcacggatatacgcacaatcaaggagaggatcaggaaactcaaggag ctacagaaggaggtggatgcccataagtccaaaatcttgtccttgaacttgagcagcgtt gggctcctccagtcagattcagaggagagcaggaagctgcgggagaggctgaaggagatg aactcgcgctgggatcgactgggaaaagcactgcagcagtggagaggagctttgcaggag gctcttatgcaatgccaggagttccatgagctcagtcacggccttctgctctggctggag aacatcgaccgcaggaggaatgagattgttcccatttcatcaggactggaccgtcacaca ctccgagcccattacagagcacttgagcaaatccagcaggagcttgtggattcggagcag agggtgagcgtcctgcaggacctctctgtccacctactggttcaggcgcagggcagtgag tgtctggaggcccaggagagggtgcatgtcatcggtaatcgtctccgcctgcttctcaag gccgtggcctctgatctgcaactgcttgagcgagagctccgaagcttgggagatacacag gatctttccgcttggtctctggctgatgatgtggaaacttctggatctgccagtcctgtg tctgtggtgaatgttcctgttcagcagcatccgctacggggcaaatgtattgtgtcagaa gcaggatcctcagccagccgcccgcaccgcaggtcccgcgggggctctgcctgcgcttcc tctcgctctggtacgtcagggcctcgaggtggcgctgctgcgggtcgctgccagtccttc ctgctgcgggtcctgcgagcggctctgcctctacagctcctgctgctgctcatcgtgggc ttagcgtgtctggtgcccatgactgaggaggactacagctgcgcccacgccaacaacttc gcccgctccttccaccccatgctccgctacaccaacggccctccgcccatatga

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