Astyanax mexicanus (Mexican tetra): 103041479
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Entry
103041479 CDS
T05042
Symbol
bckdha
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
amex
Astyanax mexicanus (Mexican tetra)
Pathway
amex00280
Valine, leucine and isoleucine degradation
amex00640
Propanoate metabolism
amex00785
Lipoic acid metabolism
amex01100
Metabolic pathways
amex01210
2-Oxocarboxylic acid metabolism
Module
amex_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
amex00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
103041479 (bckdha)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
103041479 (bckdha)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
103041479 (bckdha)
Enzymes [BR:
amex01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
103041479 (bckdha)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
103041479
NCBI-ProteinID:
XP_022520665
Ensembl:
ENSAMXG00000030349
UniProt:
A0A3B1IQE8
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Position
9:2332594..2346869
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AA seq
446 aa
AA seq
DB search
MAAVRRLQKWVGLGFHAFRQNSALNSVRALQRRAFRTQGALFQQPFDSSAEKPQFPGASA
EFVDHLEFIQPNVISGIPIYRVMDRQGQIINPSEDPNLSKETVLNFYQKMTLLNTMDRIL
YESQRQGRISFYMTNYGEEGTHVGSAAALDPTDLVFGQYREAGVLMYRGFPLDLFMAQCY
ANADDLGKGRQMPVHYGCKDLNFVTISSPLATQIPQAAGAAYAVKRENANRAVICYFGEG
AASEGDAHAGFNFSATLECPLIFFCRNNGYAISTPTNEQYRGDGIAARGPGYGMLSIRVD
GNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDH
PISRLRHYMTARDWWGEDEERAWRKQSRKLVMEAFERAERRLKPHPDLMFTDVYDQMTPG
LEKQKEAMWRHVQQYKEHYPLDLYEK
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggtgcggaggctgcagaaatgggtcggactcggttttcacgcgtttcgccaa
aattcagcattaaactcggtcagagccctgcagcggagagccttccgcacccagggggct
ctgttccagcagccgtttgattcgtcggcggagaagccgcagtttccgggagcttctgca
gagttcgtggatcatctggagtttattcagcccaacgtgatctcaggaatccccatctac
agagtgatggaccgacagggacagatcatcaacccctcagaagatccaaacctttcgaag
gagacagtattgaacttctatcagaagatgacgctgctgaacacgatggaccggattctg
tacgagtctcagagacagggccgtatctcgttctacatgacgaattacggtgaggaggga
acacacgtgggcagtgcggcggctctggacccgactgacctggtgttcgggcagtaccga
gaagcaggagtgctgatgtatcgaggtttcccgctggatctgtttatggctcagtgctat
gctaacgctgatgatcttggcaaaggtcggcagatgcccgtccactacggctgcaaagat
ctcaattttgtgaccatctcttcacccctggccactcagattccccaggcggcgggagca
gcgtacgcagtgaagcgtgagaatgcgaaccgggctgtaatctgttatttcggagaggga
gctgcgagcgaaggcgatgctcacgccggttttaacttctccgccactttggagtgccca
cttatctttttctgccgcaataacggctacgccatctccacccccaccaacgagcagtac
aggggcgacggcatcgctgcgagaggtccaggttacgggatgctctctatccgtgtggac
ggtaacgacgtgtttgcggtgtataacgctacgaaggaagcccggcgcagagccgtcgcc
gagaaccagcccttcctcatcgaggccatgacctacaggatcggtcaccacagcaccagt
gacgacagctcggcgtaccgctcggtggacgaggtgaactactgggacaagcaggaccac
cccatctcccgcctgaggcactacatgactgcgcgggactggtggggcgaggacgaggag
cgggcctggaggaagcagtcccgcaagctggtgatggaggcgttcgagcgggcggagcgc
cgcctcaagccccacccggacctgatgttcaccgacgtctacgaccagatgacccccggc
ctggagaagcagaaggaggccatgtggagacacgtccagcagtacaaggagcactacccc
ctggacctgtacgagaagtga
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