Astyanax mexicanus (Mexican tetra): 103044715
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Entry
103044715 CDS
T05042
Symbol
tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
amex
Astyanax mexicanus (Mexican tetra)
Pathway
amex04217
Necroptosis
amex04620
Toll-like receptor signaling pathway
amex04621
NOD-like receptor signaling pathway
amex05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
amex00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
103044715 (tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
103044715 (tyk2)
04621 NOD-like receptor signaling pathway
103044715 (tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
103044715 (tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
amex01001
]
103044715 (tyk2)
Enzymes [BR:
amex01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
103044715 (tyk2)
Protein kinases [BR:
amex01001
]
Non-receptor tyrosine kinases
JAK family [OT]
103044715 (tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
SH2_1
FERM_F1
WHD_CHMP7
Kinase-like
ABC1
Kdo
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
103044715
NCBI-ProteinID:
XP_049331590
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All DBs
Position
3:complement(64998353..65046241)
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AA seq
1185 aa
AA seq
DB search
MPDVPSLRSDRGGRRTMSRRGCFKSSKHGTSPEQCAPPQGPGIHVYLFWTKTGDTYFTHL
EDGEVTAEDLSIRAAQIVGITPVCHALFALYDPSSCCWYSPNHSFNSQNQSSLILHLRMR
FYFRNWHGLTEEPTVSRYAHRTGTEPAGAPLLEMSSLEYLFAQAKCDFVNDVVSLDELVD
EAQQTCFKNESLGMAVLHLSHRALQNQSTLQDVAKHTSFLRCIPRSFARHIARDNFLTKF
RIRRVFSEFVRSFQQHTVGQGHLGAQEVMYKYLSTLERLAPRFGTETFPLFHLEVRSDGD
GSGSYLNASRAHDPSQEMLCGQPTHEVMVSGTAGIKWRKISCRRAQENSYMENDYLAERR
EEGSQSRQEGETLESFCDFPEISHIAIMGANVCICRQDNSTMDLRLRSSQEARSLVSLLD
GYFRLTADAHHYLCHEVAPPRVVLSEANGLHGPILDEFVLRKLKKEAVEDGAYIVRWSVL
DYHRIILAVLNRAQNGQNPTHKQFRILRGGSGFMLEGWEREFSSVKDLTDALKTFVLKSG
QDCFTIKKCCLPRPAELSNLLVVRQGRNSSTKPVSETLNLSQLRFHQIKDKEITQKQHLG
RGTRTNIYSGCLMVRGGTEDEDESNNNHTNGKGIRVVLKILDQSHKDIALAFFETASLMS
QVSHSHLVFVHGVSVKGSENIMVEEFVELGPLDVFLHREKGRVTPQWKFTVAKQLASALC
YLEMKRLVHGNVCAKNILVARAGLEEGTSPFVKLSDPGISLTALSRGERVERIPWIAPEC
VLGGAVIGSAADKWSFGATLLEICNNGDLAMSGSTLPEKERFYETQSRLAVPSSQDLGSF
ISMCLTYDPAARPSFRTILRELTEIQIKNPDISSDCEALPDRDPSIFLKRHLKKIRDLGE
GHFGKVMLYVYDPANDGTGECVAVKTLKQEGGNHLHDSWMKEIEILKSLYHINIVKYKGC
CTELGGQVVQLIMEYLPLGSLREYLPKHRLGIAQNLLFAQQICQGMDYLHSKRYIHRDLA
ARNVLVENEGVVKIGDFGLTKYIPEGEIYYRVREDGDSPVFWYAIECLKESKFSFSSDVW
SFGVTLYEILTRCDHRQSPPTKYVEMMGVVQGQMTVMKLINLLEKHRRLPCPRDCPHEVY
MLMEQCWDFSPAQRPEFRGLAESLEEIRRSYEQQPTVRLAQINHR
NT seq
3558 nt
NT seq
+upstream
nt +downstream
nt
atgccggacgtcccgtctctccgcagtgaccggggtggacgcaggacgatgtctcggcgc
gggtgcttcaagagctcaaagcacgggacgtcccccgagcagtgcgccccgccgcagggt
cccggcatccacgtttacctgttctggaccaaaactggagacacctacttcacacacctg
gaggacggggaggtgactgccgaggacctgtccatcagagccgcccagatcgtggggatc
acgcctgtctgtcatgcgctgtttgcgctgtacgacccgtcgtcctgctgctggtacagc
cctaaccacagcttcaactcacagaaccagtccagcctgatcctgcacctacgcatgagg
ttttattttaggaactggcacgggctgactgaggagcccacagtgagccgctatgcccac
aggacgggcaccgagccggcgggcgctcctctgctggagatgtcctctctggagtatctc
ttcgctcaggcgaagtgtgacttcgtgaatgacgtggtgtcgctggacgagctggtggac
gaggcgcagcaaacctgctttaagaacgagagtctgggcatggccgtcctgcacctctcc
cacagagccctgcagaaccagtccaccctacaggacgtcgccaagcacaccagcttcctg
cgctgcatccctcgctccttcgctcgacacatcgcccgggacaacttcctcaccaagttc
cggatccgccgggtcttctcggagttcgtccgcagtttccagcagcacacggtggggcag
ggtcacctgggggcacaggaagtgatgtataagtacctgtccacgctggagcgcctggcg
ccgcgcttcggcacggagaccttccccctgttccacctggaggtccggtcggacggggac
ggcagcgggtcctacctcaacgcttcccgagctcacgacccctcgcaggagatgctgtgt
gggcagcccacccacgaggtcatggtatcgggcaccgcgggcatcaagtggagaaagatc
tcgtgccggagggctcaggagaacagttatatggagaatgattacctggcggagaggagg
gaggagggatctcagtctcggcaggaaggagaaactctggagtcgttttgtgattttcct
gaaatctctcacatcgccatcatgggagcgaacgtctgcatctgccgccaggacaactcc
accatggacctgcgtctgaggtccagtcaggaggctcgttctctggtctctctgctggac
gggtatttcaggctgacagcagacgctcatcactatctctgccatgaggtggcgccgccg
agagtggtgctcagcgaagccaacggactccacggccccatcctggatgagtttgtgctg
cggaagctgaagaaggaggcggtggaggacggggcgtatatcgtacgctggagtgttcta
gattatcatcggatcatcctcgccgtcctgaaccgagcccagaacggacagaacccgacc
cataagcagttccggatcctgcgggggggttctgggtttatgctggagggctgggagaga
gagttcagcagtgtgaaggatctgaccgacgccctgaagaccttcgtcctgaaatcagga
caggactgtttcaccatcaaaaagtgctgcctgccccgacctgcagagctgtctaacctc
ctggtggtgagacagggcaggaacagcagcactaaacccgtgtctgaaaccctcaacctg
tcccagctcagattccaccagatcaaagacaaagagataacacagaagcagcacttgggc
cgcggcaccagaaccaacatctactcaggatgtttgatggtacgcggtggaactgaagac
gaggacgaatccaacaataaccacacaaacggcaaaggcatccgagtagttctgaagatt
ctggaccagagccacaaggacatagccctggcgttcttcgagacggcgagtctgatgagt
caggtgtctcacagtcacctggttttcgttcacggagtttcagttaaaggatctgagaat
atcatggtggaggagtttgtggagttggggccgttagacgtgtttctgcacagggagaaa
ggtcgagtgacgccgcagtggaagttcacggtggcgaagcagctggccagcgctctgtgt
tacctggaaatgaagcgcctggttcatgggaacgtctgtgctaagaacatcctggtggcg
cgggccggtctggaggagggcacgtctccgttcgtgaagctcagtgacccggggatatcc
ctcaccgctctctcacgaggagagcgggtggagcgtatcccgtggatagcgccggagtgt
gtgctgggtggtgcagtgattggcagcgctgcagataagtggagttttggagccacgctg
ctggagatctgcaacaacggagatctggccatgagcggcagcaccttacctgagaaagag
cgtttctatgagactcagagtcggctggcggttccctcctctcaggatttgggcagtttt
atcagcatgtgtttaacctacgacccggcggctcgcccgtccttcagaaccatcctcaga
gaactgaccgagatccagatcaagaatccggatatttcttcagactgtgaggctcttcca
gatcgagatcccagtattttccttaaacgccacctgaagaaaatccgagacctgggggag
gggcactttgggaaggtgatgctgtacgtgtatgacccggcgaatgacgggacgggggag
tgcgtggcggtgaagacgctgaagcaggagggagggaatcacctgcacgactcctggatg
aaggagatcgagatcctgaaatcactttaccacattaacatcgtcaaatacaagggctgc
tgcactgaactgggtggtcaggtggttcagctgatcatggagtatcttcctctggggagt
ctcagagaatatctccctaaacaccgactgggaatcgcccagaacctgctcttcgcccag
cagatctgccaggggatggattacctgcactctaagcggtatattcaccgggacctggcg
gcgaggaacgttctggtggagaatgagggcgtggtgaagatcggcgacttcggactgacc
aagtacattcctgagggggagatctactaccgggtccgggaggatggagacagccccgtg
ttctggtatgctatagagtgtctgaaggaaagtaagttctccttctcctcggacgtttgg
tcgttcggtgtgacgctgtacgagattctgactcgctgtgatcatcgccagagtccgcct
acgaaatatgtggagatgatgggcgtggttcagggtcagatgactgtgatgaagctcatt
aacctcctggagaaacacaggaggctgccgtgcccacgggactgcccacacgaggtgtat
atgttgatggagcagtgctgggatttctctccggcgcagcggccggagttccgcggtctc
gccgagtctctggaggaaatccggcggtcgtacgaacagcagccgaccgtccggctcgcc
cagatcaaccatcgctaa
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