Actinosynnema mirum: Amir_1333
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Entry
Amir_1333 CDS
T00957
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
ami
Actinosynnema mirum
Pathway
ami00010
Glycolysis / Gluconeogenesis
ami00020
Citrate cycle (TCA cycle)
ami00620
Pyruvate metabolism
ami00785
Lipoic acid metabolism
ami01100
Metabolic pathways
ami01110
Biosynthesis of secondary metabolites
ami01120
Microbial metabolism in diverse environments
ami01200
Carbon metabolism
ami01210
2-Oxocarboxylic acid metabolism
Module
ami_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ami00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Amir_1333
00020 Citrate cycle (TCA cycle)
Amir_1333
00620 Pyruvate metabolism
Amir_1333
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Amir_1333
Enzymes [BR:
ami01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Amir_1333
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Paralog
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ACU35285
UniProt:
C6W9C2
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All DBs
Position
complement(1476231..1478990)
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AA seq
919 aa
AA seq
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MAPQNHGTTPERVRVIRDGLASHLPDIDPEETSEWLESFDAALKGGGQQRARYLMLRLLE
RARESHVGVPALTSTDYVNTIPTEREPWFPGDEEVERRYRAWVRWNAAITVHRAQRPGVG
VGGHISTYASSASLYEVGFNHFFRGKDHPGGGDQVFVQGHASPGVYARAFLEGRLTTDQL
DGFRQEYSHGGLGKGLPSYPHPRLMPEFWEFPTVSMGLGPMNAIYQARFNRYLQSRGIKD
TSQQHVWAFLGDGEMDEPESRGLLQLAANEQLDNLTFVVNCNLQRLDGPVRGNGKIIQEL
ESFFRGAGWNVIKVIWGREWDSLLHADRDGALVNLMNQTPDGDFQTYKANDGAYVKEHFF
GRDPRTKELVTAMSDDDVWNLKRGGHDYRKVFAAYQAAVSHNGQPTVILAKTIKGYGLGE
RFAARNATHQMKKMSHDDLKSFRDSLRIPIADKDLDPYLPPYYHPGKDAPEIQYLLERRK
QLGGFVPERRNTAKPLVLPGDKVYDVVKRGSGKQEVATTMAFVRLVRDLIKDPEIGKRIV
PIIPDEARTFGMDSMFPSQKIYNPNGQLYTSVDAELMLAYKESEQGQILHEGINEAGSTA
SFTAVGTSYATHGEPMIPIYIFYSMFGFQRTGDGLWAAGDQMARGFVLGATAGRTTLTGE
GLQHADGHSLLLAHTNPAAVAYDPAWSFEVAHIVKDGLRRMYGEDAENVFYYLTIYNEPY
RQPAEPEDLDVEGLLKGLYRYQRSEGEGGPKAQLLASGVGVPWALKAARLLADDWGVHAD
VWSATSYSELRREAVEVDRHNLLNPDKEPRVPYVTQVLKDAQGPVVAVSDWMTAVPDLIR
PYVPTDMTTLGADGFGFSDTRPAARRHFLIDAESVVVATLAALAKRGEVPQQSVVDAARK
YRIDDVSAAGPSTSDAGLA
NT seq
2760 nt
NT seq
+upstream
nt +downstream
nt
ttggccccgcagaaccacggcaccactcccgagcgggtgcgcgtcatcagggacggtttg
gcctcccacctcccggacatcgacccggaggagacctcggagtggctggagtcgttcgac
gccgcgctcaagggcggcggccagcagcgagcccgctatctgatgctgcggctgctcgag
cgcgcgagggagtcccacgtcggggtgcccgcgctgaccagcaccgactacgtgaacacc
atccccaccgagcgggagccctggttccccggtgacgaggaggtggagcgccgctaccgc
gcctgggtgcgctggaacgcggcgatcacggtgcaccgcgcgcagcgaccgggtgtgggc
gtcggcggccacatctcgacgtatgcttcgtcggccagcctgtacgaggtgggcttcaac
cacttcttccggggcaaggaccaccccggcggcggcgaccaggtcttcgtgcagggccac
gcctcccccggcgtctacgcgcgcgccttcctggaaggccggttgaccaccgaccagctg
gacggcttccgccaggagtactcgcacggcggcctcggcaagggcctgccgtcgtacccg
cacccgcggttgatgccggagttctgggagttcccgaccgtctccatgggcctcggcccg
atgaacgcgatctaccaggcccggttcaaccggtacctccagtcgcgcggcatcaaggac
acctcgcagcagcacgtctgggcgttcctcggcgacggcgagatggacgagcccgagtcg
cgcggcctgctccagctcgcggcgaacgagcagctggacaacctcaccttcgtggtcaac
tgcaacctgcagcgcctcgacggcccggtgcgcggcaacggcaagatcatccaggagctg
gagtccttcttccggggcgccggctggaacgtcatcaaggtcatctggggccgcgagtgg
gactcgctgctgcacgcggaccgcgacggcgcgctggtcaacctgatgaaccagaccccc
gacggcgacttccagacgtacaaggccaacgacggcgcgtacgtcaaggagcacttcttc
ggccgcgacccgcggacgaaggagctggtcacggccatgtcggacgacgacgtgtggaac
ctcaagcgcggcggccacgactaccgcaaggtgttcgcggcctaccaggcggcggtctcg
cacaacggccagccgaccgtgatcctcgccaagacgatcaagggctacggcctcggcgag
cggttcgcggcgcgcaacgccacgcaccagatgaagaagatgtcccacgacgacctgaag
tcgttccgggacagcctgcgcatcccgatcgcggacaaggacctcgacccgtacctgccg
ccgtactaccaccccggcaaggacgccccggagatccagtacctgctggagcgccgcaag
cagctcggcgggttcgtgcccgagcgccgcaacaccgccaagccgctggtgctgcccggc
gacaaggtctacgacgtggtcaagcgcggctcgggcaagcaggaggtcgccacgacgatg
gcgttcgtccggctggtccgcgacctcatcaaggacccggagatcggcaagcggatcgtg
ccgatcatcccggacgaggcgcgcacgttcggcatggactcgatgttcccgtcgcagaag
atctacaacccgaacgggcagctctacacctccgtggacgccgagctgatgctggcgtac
aaggagtccgagcagggccagatcctgcacgagggcatcaacgaggccggctcgacggcg
tcgttcacggcggtcggcacctcgtacgccacgcacggcgagccgatgatcccgatctac
atcttctactcgatgttcgggttccagcggaccggcgacggcctgtgggcggcgggcgac
cagatggcgcgcggcttcgtgctgggcgccacggcgggtcgcaccacgctgaccggcgag
ggcctgcagcacgccgacgggcactcgctgctgctcgcgcacaccaacccggcggcggtc
gcctacgacccggcctggtcgttcgaggtggcgcacatcgtcaaggacggcctgcggcgg
atgtacggcgaggacgccgagaacgtcttctactacctgacgatctacaacgagccgtac
cggcagcccgccgagcccgaggacctggacgtggagggcctgctcaagggcctgtaccgc
taccagaggtccgagggcgagggcggcccgaaggcgcagctgctcgcgtccggcgtcggc
gtcccgtgggcgctcaaggccgcccggctgctggccgacgactggggcgtgcacgccgac
gtgtggtcggcgacgtcgtactcggagctgcgccgcgaggccgtcgaggtcgaccggcac
aacctgctgaacccggacaaggagccgcgcgtcccgtacgtgacgcaggtgctcaaggac
gcgcagggcccggtcgtggcggtgtcggactggatgacggcggtgccggacctgatccgc
ccgtacgtgccgaccgacatgaccacgctgggcgcggacggcttcggcttctccgacacc
cgcccggccgcgcgcaggcacttcctgatcgacgccgagtcggtcgtggtggccaccctg
gccgcgctggccaagcgcggcgaggtgccgcagcagtccgtcgtggacgcggcgcgcaag
taccgcatcgacgacgtgtcggcggccggtccgtccacctcggacgcgggcctggcctga
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