KEGG   Actinosynnema mirum: Amir_2211
Entry
Amir_2211         CDS       T00957                                 
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
ami  Actinosynnema mirum
Pathway
ami00270  Cysteine and methionine metabolism
ami00450  Selenocompound metabolism
ami00670  One carbon pool by folate
ami01100  Metabolic pathways
ami01110  Biosynthesis of secondary metabolites
ami01230  Biosynthesis of amino acids
ami04980  Cobalamin transport and metabolism
ami04981  Folate transport and metabolism
Module
ami_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:ami00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    Amir_2211
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    Amir_2211
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Amir_2211
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Amir_2211
   04980 Cobalamin transport and metabolism
    Amir_2211
Enzymes [BR:ami01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     Amir_2211
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding CdhD
Other DBs
NCBI-ProteinID: ACU36153
UniProt: C6WIB0
LinkDB
Position
2446273..2449809
AA seq 1178 aa
MSDRVSSPLLDALTERVVVADGAMGTMLQSFDLSLDDFAGHEGCNEILNTTRPDVVRAVH
RGYLEAGADAVETNTFGANLSNFSDYGIQDRIFELSRLGAQLAREAADEHSEPGRPRFVL
GSVGPGSKLPTLGHVAYSVLRDSYVEQIRGLLVGGSDAIIVETSQDLLQTKAAIVGARRA
MDAEGLRVPIIAQVTVETTGTMLLGSEIGAALTALEPLGIDLVGLNCATGPAEMSEHLRH
IAKHARIPLSVMPNAGLPQLGPNGAVYPLGPEELAQALRGFATEFGARLVGGCCGTTAEH
VRQVAAAVRDLGPTTRRPRPEPGVSSLYQAVPFQQDASVLMIGERTNANGSKAFREAMLA
DRWDDCVGIARDQTRDGAHLIDLNIDYVGRDGVADMSALASRLATASTLPIMLDSTEPEV
LQAGLEHLGGRCAVNSVNYEDGDGPDSRFQRIMRLVAEHGAAVVGLCIDEEGQARTAEWK
VRVAIRIIEDLVGNWGLRHGDIIIDCLTFPISTGQEEVRRDGVETIEAIRELKRRYPEVR
TTLGLSNVSFGLNPAARQVLNSVFLHECVQAGLDTAIVHASKIVPMARIPDEQRAVALDL
VYDRRREGYDPLQRLMELFEGVTTSASKATRAQELAALPLFERLQRRIVDGERNGLEADL
DEALTRRPALQIINDTLLAGMKTVGELFGSGQMQLPFVLQSAEVMKTAVAHLEPHMERSD
DGGKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVINLGIKQPISAILDAAENHRADAIG
MSGLLVKSTVIMKENLEEMNSRGVAARWPVLLGGAALTRAYVENDLTDTYLGEVRYARDA
FEGLRLMDAVMAAKRGESPLIDPEAERKAAERKARRERSLRIAAERKAAQPEPEPVSRSD
VAADLPVPTPPFWGTRVVKGVPLGDYSALLDERATFMGQWGLRGSRGSGPSYEELVETEG
RPRLRYWLERLATEGVLAHAAVVYGYFPCVSEGDSLVILGEPSVDAPEVTRFAFPRQKRD
RRLCLADFWRPRESGEVDVVPFQLVTMGQPIADYANELFAKDAYREYLEVHGLGVQLTEA
LAEYWHKRVREELTWPGGGVVAAEDPADVEEYFKLGYRGARYSLGYGACPDMEDRTKVVA
LLEPGRIGVKLSEELQLHPEQSTDAFIAHHPEAKYFNA
NT seq 3537 nt   +upstreamnt  +downstreamnt
atgtcggatcgtgtctcgtcccccctgctggacgcactcaccgaacgcgtggtcgtggcc
gacggggccatgggcaccatgctccagtcgttcgacctgtccctcgacgacttcgcaggc
cacgagggctgcaacgagatcctgaacaccacccggcccgacgtggtgcgcgccgtgcac
cgcggctacctggaggcgggcgccgacgcggtcgagacgaacaccttcggcgcgaacctg
tccaacttctccgactacggcatccaggaccgcatcttcgagctgtcccgcctcggcgcc
cagctcgcccgcgaggccgccgacgagcactccgagccgggacgcccgcgcttcgtgctc
ggctcggtcggccccggctccaagctgcccaccctcggccacgtcgcctactccgtgctg
cgcgactcctacgtggagcagatccgcggcctgctggtcggcggctccgacgcgatcatc
gtcgagacctcgcaggacctgctccagaccaaggccgccatcgtcggggcaaggcgcgcc
atggacgccgagggcctgcgcgtgccgatcatcgcccaggtcaccgtcgagaccaccggc
accatgctgctgggctccgagatcggcgccgccctcaccgccctcgaaccgctcggcatc
gacctggtcggcctgaactgcgccaccggccccgccgagatgagcgagcacctgcggcac
atcgccaagcacgcccgcatcccgctctcggtcatgcccaacgcgggcctgccgcagctc
ggccccaacggcgcggtctacccgctcggccccgaggagctggcgcaggcgctgcgcggg
ttcgccaccgagttcggcgcccgcctggtcggcggctgctgcggcaccaccgccgagcac
gtccgccaggtcgccgccgccgtgcgcgacctcggccccaccacccgccgcccgcgcccc
gagccgggcgtgtcctcgctctaccaggccgtgccgttccagcaggacgcgtccgtgctg
atgatcggcgagcgcaccaacgccaacggctccaaggccttccgcgaggccatgctcgcc
gaccgctgggacgactgcgtcggcatcgcccgcgaccagacccgcgacggcgcgcacctg
atcgacctgaacatcgactacgtgggccgcgacggcgtcgccgacatgtccgcgctcgcc
tcccgcctggccaccgcgtccaccctgccgatcatgctcgactccaccgagcccgaggtg
ctgcaggccggtctggagcacctgggcgggcgctgcgcggtcaactcggtcaactacgag
gacggcgacggcccggactcgcggttccagcgcatcatgcggctggtcgccgagcacggc
gcggccgtcgtcggcctgtgcatcgacgaggagggccaggcccgcaccgccgagtggaag
gtccgggtggccatccgcatcatcgaggacctggtcggcaactggggcctgcggcacggc
gacatcatcatcgactgcctgaccttccccatctccaccggccaggaggaggtgcggcgc
gacggcgtggagaccatcgaggccatccgcgagctcaagcgccgctaccccgaggtgcgc
accacgctcgggctgtccaacgtgtccttcggcctcaacccggccgccaggcaggtgctg
aactcggtgttcctgcacgagtgcgtgcaggccgggctggacaccgcgatcgtgcacgcc
tccaagatcgtgccgatggcgcgcatccccgacgagcagcgcgccgtcgcgctcgacctg
gtctacgaccgcaggcgtgagggctacgacccgctgcagcggctcatggagctgttcgag
ggcgtcaccacctccgcgtccaaggccacccgcgcccaggagctggccgcgctgccgctg
ttcgagcggttgcagcggcgcatcgtggacggcgagcgcaacggcctcgaggccgacctg
gacgaggcgctgacccggcggcccgcgctccagatcatcaacgacaccctgctggcgggc
atgaagaccgtcggcgagctgttcggctccggccagatgcagctgccgttcgtgctccag
tccgccgaggtcatgaagaccgccgtcgcgcacctggagccgcacatggagcgctccgac
gacggcggcaagggccgcatcgtgctcgccaccgtcaagggcgacgtgcacgacatcggc
aagaacctggtggacatcatcctgtccaacaacggctacgaggtcatcaacctcggcatc
aagcagcccatcagcgcgatcctcgacgccgccgagaaccaccgcgccgacgccatcggc
atgtccggcctgctcgtcaagtccacggtgatcatgaaggagaacctggaggagatgaac
tcgcgcggggtcgccgcccgctggccggtgctgctcggcggcgccgccctcacccgcgcg
tacgtggagaacgacctcaccgacacctacctcggcgaggtccgctacgcccgcgacgcg
ttcgagggcctgcggctgatggacgcggtcatggcggccaagcgcggcgagtccccgctg
atcgacccggaggccgagcgcaaggccgccgagcgcaaggcccgccgcgagcggtcgctg
cgcatcgccgccgagcgcaaggccgcccagcccgagccggaaccggtgtcccgctcggac
gtggccgccgacctgcccgtccccaccccgccgttctggggcacccgcgtggtcaagggc
gtgccgctgggcgactactcggcgctgctcgacgagcgcgccacgttcatgggccagtgg
gggctgcgcggctcgcgcggcagcggaccgtcctacgaggagctggtcgagaccgagggc
cgcccccggctgcgctactggctggagcggctggccaccgagggcgtcctcgcgcacgcc
gccgtggtctacgggtacttcccgtgcgtgtccgagggcgactcgctggtgatcctgggc
gagccgtcggtggacgcgcccgaggtgacccggttcgcgttcccccggcagaagcgggac
cggcggctgtgcctggccgacttctggcgcccgcgcgagtccggcgaggtcgacgtggtg
ccgttccagctggtcaccatggggcagccgatcgccgactacgccaacgagctgttcgcc
aaggacgcgtaccgcgagtacctggaggtgcacggcctgggcgtgcagctcaccgaggcg
ctcgccgagtactggcacaagcgggtgcgcgaggagctgacctggccgggcggcggggtc
gtcgcggccgaggacccggccgacgtggaggagtacttcaagctcggctaccggggcgcc
cgctactccctgggctacggggcgtgccccgacatggaggaccggaccaaggtcgtcgcg
ctgctcgaaccgggccgcatcggcgtgaagctgtccgaggagctccagctgcaccccgag
cagtccaccgacgccttcatcgcccaccaccccgaggcgaagtacttcaacgcctga

DBGET integrated database retrieval system