Actinosynnema mirum: Amir_4385
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Entry
Amir_4385 CDS
T00957
Name
(GenBank) Prenyltransferase/squalene oxidase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
ami
Actinosynnema mirum
Pathway
ami00909
Sesquiterpenoid and triterpenoid biosynthesis
ami01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
ami00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
Amir_4385
Enzymes [BR:
ami01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
Amir_4385
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
Amir_4385
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Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
Gp38_N
Motif
Other DBs
NCBI-ProteinID:
ACU38234
UniProt:
C6WK21
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Position
complement(5182451..5184133)
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AA seq
560 aa
AA seq
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MTSVHVDPDPFTDVLDRAISEGAEALFRAQRPDGVFDYSEDNLTSTLGTVGALSALHYAD
PEGSADLIEAGAGWLRRTQNEDGGWAMVPGLPSEAGPTAVSSAVLHLVDPVGSAAHVESG
QRWMGDHGGLEAIPHPEVVSWCRQYYGFVGWLAPEDMRRFPLELALLPGLYRRLFDLRVP
MASALGLAQAKHKPLNPLQRLFARLGTPNALTAIRQVYEHEGSTGAWCENAWVTGLVCTG
LARADLAPDMVAAAVGWFRRTMDPDGWWQTGPLDAAWTMYAVRGLTEVGYADDPRLVASR
DLFTRLQQHRPFLAFGCPPGYWGWAGTEGWPSTLETGEILSVLCRLPGDEQAHSVERGVD
WLTRVQDTRGSWGLCVKNTKVANSGPCPMTTVQAVDALLDAGVPATDPRVRRALTWLGKA
QLPDGSFESVWYRQHTMGTAAVLETFSRVGRADDPVARKAVAWLERARLDDGSWGDGAGA
PGTVEETGWAVSALLASGADAAGLRTGVDWLLAHRADGGGWPSEIVHEYVRHVSRYTNPA
FAQGMALRALGRYRDAVAKP
NT seq
1683 nt
NT seq
+upstream
nt +downstream
nt
atgacctcggtccacgtcgacccggacccgttcacggacgtcctagaccgcgccatctcc
gagggcgccgaggccctgttccgcgcccagcgcccggacggcgtgttcgactacagcgag
gacaacctcacctccaccctcggcaccgtcggcgccctgtccgccctgcactacgccgac
cccgagggcagcgccgacctgatcgaggcgggcgcgggctggttgcgccgcacccagaac
gaggacggcggctgggccatggtccccggcctgcccagcgaggcgggccccaccgccgtc
tcctccgccgtgctgcacctggtcgacccggtcggcagcgccgcccacgtcgagtccggg
cagcgctggatgggcgaccacggcggcctggaggccatcccgcaccccgaggtcgtctcc
tggtgccgccagtactacggcttcgtcggctggctcgcccccgaggacatgcgccgcttc
cccctggagctggcgctgctgcccggcctctaccgcaggctcttcgacctgcgcgtcccc
atggcctccgcgctcggcctggcccaggccaagcacaagccgctcaacccgctgcagcgc
ctgttcgcccgcctcggcacgccgaacgcgctcaccgccatccgccaggtctacgagcac
gagggctccaccggcgcgtggtgcgagaacgcctgggtcaccggcctggtctgcaccggc
ctcgcccgcgccgacctcgcccccgacatggtcgccgccgccgtcggctggttccgccgc
accatggaccccgacggctggtggcagaccggcccgctcgacgccgcctggacgatgtac
gcggtgcgcggcctcaccgaggtcggctacgccgacgacccccggctcgtcgcctccagg
gacctgttcacgcgcctgcagcagcaccgcccgttcctggcgttcggctgcccgcccggc
tactggggctgggcgggcaccgagggctggccgtccacgctggagaccggcgagatcctg
tccgtgctgtgcaggctccccggcgacgagcaggcgcactcggtcgagcgcggcgtcgac
tggctcacccgcgtgcaggacacccgcggctcctggggcctgtgcgtgaagaacaccaag
gtcgccaacagcggcccgtgccccatgaccaccgtgcaggccgtcgacgcgctgctcgac
gcgggcgtgcccgccaccgaccccagggtgcgccgcgccctgacctggctggggaaggcc
cagctgccggacggctcgttcgagtcggtctggtaccgccagcacaccatgggcaccgcc
gccgtcctggagaccttctccagggtcggccgcgccgacgacccggtcgcccgcaaggcc
gtggcctggttggagcgcgcccggctcgacgacggctcctggggcgacggcgcgggcgcg
cccggcacggtcgaggagaccggctgggcggtgtcggcgctgctcgcctccggcgcggac
gcggccggtctgcgcaccggcgtcgactggctgctcgcccaccgcgcggacggcggcggg
tggccctcggagatcgtccacgagtacgtgcggcacgtcagccgctacaccaaccccgcg
ttcgcccagggcatggcgctgcgcgcgctgggccgctaccgggacgcggtcgccaagccc
tga
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