Actinosynnema mirum: Amir_6253
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Entry
Amir_6253 CDS
T00957
Name
(GenBank) 2-oxoglutarate dehydrogenase, E1 subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
ami
Actinosynnema mirum
Pathway
ami00020
Citrate cycle (TCA cycle)
ami00630
Glyoxylate and dicarboxylate metabolism
ami00785
Lipoic acid metabolism
ami01100
Metabolic pathways
ami01110
Biosynthesis of secondary metabolites
ami01120
Microbial metabolism in diverse environments
ami01200
Carbon metabolism
ami01210
2-Oxocarboxylic acid metabolism
Module
ami_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ami_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
ami00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
Amir_6253
00630 Glyoxylate and dicarboxylate metabolism
Amir_6253
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Amir_6253
Enzymes [BR:
ami01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
Amir_6253
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
Amir_6253
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
Amir_6253
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
Amir_6253
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
ACU40057
UniProt:
C6WIY1
LinkDB
All DBs
Position
7337165..7340893
Genome browser
AA seq
1242 aa
AA seq
DB search
MSSSPASQFGPNEWLVEEMYEQFLADPSSVDPAWHDFFADYKSTQRNGSTTTAAPTAATQ
ADTGKAASSGAPAAAKQAASTAPAAKTPAAPAPSSAPKPKAAAPAKPAAAPAAKPAPAQA
AKAAPVQQAKGPEQKQLRGAAAAIAKNMELSLTVPTATSVRAVPAKLLADNRIVINNHLK
RTRGGKVSFTHLIGYAVVRALQAFPNMNRHYAEINNKPHVVTPEHVNFGLAIDLPGKDGS
RTLVVASVKGCENMTFTQFWQAYEDLIRKARGGSLTAEDFSGTTISLTNPGTIGTNHSVP
RLTAGQGTIVGVGAMEYPAHFQGTSEQALTDMGVSKIITLTSTYDHRIIQGAESGEFLKR
VHQLLLGEDGFYDDVFTSLRLPYEPIRWVADIPEGAVDKTARVIELIDAYRTRGHLMADT
DPLNYRQRKHQDLDVLSHGLTLWDLDREFPVGGFAGKERMRLRDILGVLRNSYCRTVGVE
YMHILDPEERLWIQERVEVPHEKPPATVQKYILSKLNAAEAFETFLQTKYVGQKRFSLEG
GETVIPLLDAVLDKAAEHELDEVVIGMPHRGRLNVLANIVGKPISQIFREFEGNLDPGQA
HGSGDVKYHLGAEGKYFRMFGDGETKVSLTANPSHLEAVDPVLEGIVRAKQDILDMGGES
FPVLPVAMHGDAAFAGQGVVAETLNLALVRGYRTGGTVHVIVNNQVGFTTAPENSRSSKY
STDVAKMIGAPVFHVNGDDPEACYWVAKLAVDYRQAFNKDVVIDMVCYRRRGHNEGDDPS
MTQPAMYDVIDTKRSVRKTYTEALIGRGDISVEEAEKALQDFSSQLEHVFNEVRELEKHP
IKASPSVEEEQQVPAKLPTGVPREVLERIADAHVELPEGFTPHPRVKPVLERRAKMAREG
GIDWAYAELLAFGSLVHEGRTVRLAGQDSRRGTFTQRHATLIDRKTGQEYTPIQNLADDQ
GKFMVYDSVLSEFAALGFEYGYSVANPDALVLWEAQFGDFVNGAQPIIDEFISSGEAKWG
QVSDVVLLLPHGHEGQGPDHTSGRIERFLQLCAEGSMTIAVPSTPANYFHLLRRHALDGV
NRPLVVFTPKSMLRLKAAVSPVEDFVEERFKSVIDDAAIEDNSAVTKVLLCSGKIYYELV
AEREKRGAKDTAIVRVEQLYPVPKRKLNEALEAYPNANDVRWVQEEPANQGAWTFYGLHL
PELLPERYRLTRVSRRRMAAPSAGSSKVHEVEQREIITKAFE
NT seq
3729 nt
NT seq
+upstream
nt +downstream
nt
gtgtccagcagtcctgcttcacagttcggccccaacgagtggttggtcgaggagatgtac
gagcagttcctcgccgatccgtcgtcggtagaccccgcgtggcacgacttcttcgccgac
tacaagtcgacgcagcgcaacgggtccaccacgaccgccgcccccacggcggccacccag
gctgacaccgggaaggccgcgtcgtcgggcgcgcccgcggcggccaagcaggccgcgagc
accgcgcccgccgccaagacgcccgccgcacccgctccgtcgagcgcccccaagccgaag
gccgcggcgcccgccaagcccgctgccgccccggccgccaagcccgctcccgcgcaggcc
gccaaggccgcgccggtgcagcaggcgaaggggcccgagcagaagcagctgcgcggagcc
gcggcggcgatcgccaagaacatggagctgtcgctgacggttccgacggcgaccagcgtg
cgcgccgtcccggcgaagctgctggccgacaaccggatcgtgatcaacaaccacctcaag
cgcacgcggggcgggaaggtctccttcacgcacctgatcggctacgcggtggtccgggcg
ctccaggcgttcccgaacatgaaccggcactacgccgagatcaacaacaagccgcacgtg
gtcacgcccgagcacgtgaacttcggcctggcgatcgacctgcccggcaaggacggcagc
cgcacgctggtcgtcgcctcggtcaagggctgcgagaacatgacgttcacgcagttctgg
caggcctacgaggacctgatccgcaaggcccgcggcggctccctgaccgccgaggacttc
tccggcaccacgatctcgctgaccaaccccggcaccatcggcacgaaccactcggttccg
cgcctgaccgcaggccagggcacgatcgtcggcgtcggcgcgatggagtaccccgcgcac
ttccagggcaccagcgagcaggccctgaccgacatgggcgtcagcaagatcatcacgctg
acctccacgtacgaccaccgcatcatccagggcgcggagtcgggcgagttcctcaagcgc
gtccaccagctcctgctgggcgaggacggcttctacgacgacgtcttcacgtcgctgcgc
ctgccgtacgagccgatccgctgggtggccgacatccccgagggcgcggtcgacaagacc
gcccgcgtcatcgagctgatcgacgcgtaccgcacgcgcggccacctgatggccgacacg
gacccgctgaactaccgccagcgcaagcaccaggacctcgacgtcctgtcgcacggcctg
accctgtgggacctggaccgggagttcccggtcggcgggttcgcgggcaaggagcggatg
cgcctgcgcgacatcctgggcgtgctgcgcaactcctactgccgcaccgtcggcgtggag
tacatgcacatcctcgacccggaggagcgcctctggatccaggagcgcgtcgaggtcccg
cacgagaagcccccggccaccgtgcagaagtacatcctgtcgaagctcaacgccgccgag
gcgttcgagaccttcctgcagaccaagtacgtcggccagaagcgcttctcgctggagggc
ggcgagaccgtcatcccgctgctcgacgcggtgctggacaaggccgccgagcacgagctg
gacgaggtcgtcatcgggatgccgcaccgcggtcgcctgaacgtcctggccaacatcgtg
ggcaagccgatctcgcagatcttccgcgagttcgagggcaacctcgaccccggccaggcg
cacggctccggcgacgtcaagtaccacctgggcgccgagggcaagtacttccggatgttc
ggcgacggcgagacgaaggtgtcgctgaccgcgaacccgtcgcacctggaggccgtggac
ccggtgctggagggcatcgtccgcgccaagcaggacatcctggacatgggcggcgagagc
ttcccggtgctgcccgtcgccatgcacggcgacgcggcgttcgccggccagggcgtggtc
gccgagacgctgaacctggcgctcgtgcgcggctaccgcaccggcggcacggtccacgtg
atcgtcaacaaccaggtcggcttcaccaccgcgccggagaactcgcgctcgtcgaagtac
tcgacggacgtcgcgaagatgatcggcgcgccggtgttccacgtgaacggcgacgacccc
gaggcctgctactgggtggcgaagctggcggtcgactaccgccaggcgttcaacaaggac
gtcgtcatcgacatggtgtgctaccgccgtcgcgggcacaacgagggcgacgacccgtcg
atgacgcagccggcgatgtacgacgtgatcgacaccaagcgctcggtgcgcaagacctac
accgaggcgctgatcggtcgcggcgacatctccgtggaggaggcagagaaggccctccag
gacttctcctcgcagctggagcacgtcttcaacgaggtgcgcgagctggagaagcacccg
atcaaggcgtccccctcggtggaggaggagcagcaggtcccggcgaagcttccgaccggg
gtgccgcgcgaggtgctggagcgcatcgcggacgcgcacgtggagctgcccgagggcttc
accccgcacccgcgcgtcaagccggtgctggagcggcgcgccaagatggcccgcgagggc
ggcatcgactgggcgtacgcggagctgctggcgttcggctcgctggtgcacgagggccgc
acggtccgcctcgccgggcaggactcgcggcgcggcacgttcacccagcggcacgcgacc
ctgatcgaccgcaagaccggtcaggagtacacgccgatccagaacctggccgacgaccag
ggcaagttcatggtctacgactcggtgctgtcggagttcgcggcgctcggcttcgagtac
ggctactcggtggcgaacccggacgcgctggtgctgtgggaggcgcagttcggcgacttc
gtcaacggcgcgcagccgatcatcgacgagttcatctcgtccggtgaggcgaagtggggc
caggtctcggacgtcgtgctgctgctgccgcacggccacgagggccagggtcccgaccac
acgtcggggcgcatcgagcggttcctccagctgtgcgccgagggctcgatgaccatcgcg
gtgccgtcgacgcccgcgaactacttccacctgctgcgcaggcacgccctcgacggcgtg
aaccggccgctggtggtgttcacccccaagtcgatgctgcgcctgaaggccgccgtcagc
ccggtggaggacttcgtcgaggagcgcttcaagtcggtcatcgacgacgcggcgatcgag
gacaactcggccgtcacgaaggtcctgctgtgcagcggcaagatctactacgagctggtg
gccgagcgcgagaagcggggcgcgaaggacaccgcgatcgtgcgcgtcgagcagctgtac
ccggtgccgaagcggaagctgaacgaggcgctggaggcctacccgaacgcgaacgacgtg
cgctgggtccaagaggagcccgcgaaccagggcgcgtggacgttctacggcctgcacctg
ccggagctgctgccggagcgctaccgcctgacccgcgtgtcccgccgccgcatggccgcc
ccgtcggccgggtcgtcgaaggtgcacgaggtcgagcagcgcgagatcatcacgaaggcc
ttcgagtag
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