KEGG   Alligator mississippiensis (American alligator): 106736997
Entry
106736997         CDS       T03087                                 
Symbol
MAP2K2
Name
(RefSeq) mitogen-activated protein kinase kinase 2
  KO
K04369  mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]
Organism
amj  Alligator mississippiensis (American alligator)
Pathway
amj04010  MAPK signaling pathway
amj04012  ErbB signaling pathway
amj04068  FoxO signaling pathway
amj04140  Autophagy - animal
amj04148  Efferocytosis
amj04150  mTOR signaling pathway
amj04210  Apoptosis
amj04218  Cellular senescence
amj04270  Vascular smooth muscle contraction
amj04370  VEGF signaling pathway
amj04371  Apelin signaling pathway
amj04540  Gap junction
amj04620  Toll-like receptor signaling pathway
amj04810  Regulation of actin cytoskeleton
amj04910  Insulin signaling pathway
amj04912  GnRH signaling pathway
amj04916  Melanogenesis
amj05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:amj00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    106736997 (MAP2K2)
   04012 ErbB signaling pathway
    106736997 (MAP2K2)
   04370 VEGF signaling pathway
    106736997 (MAP2K2)
   04371 Apelin signaling pathway
    106736997 (MAP2K2)
   04068 FoxO signaling pathway
    106736997 (MAP2K2)
   04150 mTOR signaling pathway
    106736997 (MAP2K2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    106736997 (MAP2K2)
   04148 Efferocytosis
    106736997 (MAP2K2)
  09143 Cell growth and death
   04210 Apoptosis
    106736997 (MAP2K2)
   04218 Cellular senescence
    106736997 (MAP2K2)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    106736997 (MAP2K2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    106736997 (MAP2K2)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    106736997 (MAP2K2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    106736997 (MAP2K2)
   04912 GnRH signaling pathway
    106736997 (MAP2K2)
   04916 Melanogenesis
    106736997 (MAP2K2)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    106736997 (MAP2K2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    106736997 (MAP2K2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:amj01001]
    106736997 (MAP2K2)
Enzymes [BR:amj01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     106736997 (MAP2K2)
Protein kinases [BR:amj01001]
 Serine/threonine kinases: STE group
  STE7 family
   106736997 (MAP2K2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Pkinase_fungal Kinase-like Haspin_kinase Seadorna_VP7 YacG APH Kdo
Other DBs
NCBI-GeneID: 106736997
NCBI-ProteinID: XP_019340939
LinkDB
Position
Un
AA seq 391 aa
PWQVLKLFFFLLPPFRPCCSTRANLVDLQKKLEELELDEQQKKRLEAFLTQKAKVGELKD
DDFERISELGAGNGGVVTKVQHKPSGLIMARKLIHLEIKPAIRNQIIRELQVLHECNSPY
IVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEEILGKVSIAVLRGLAYLREKHQ
IMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSD
IWSMGLSLVELSIGRYPIPPPDSKELEAIFGRPVVDGAEGETHSISPRPRPPGRPVSGHG
MDSRPAMAIFELLDYIVNEPPPKLPHGVFTQDFQEFVNKCLIKNPAERADLKMLMNHTFI
KRSEVEEVDFAGWLCKTLRLNQPSTPTRTAM
NT seq 1176 nt   +upstreamnt  +downstreamnt
ccctggcaagtgctaaagctttttttttttctcctccccccttttcgtccctgttgctcc
actagagccaacctcgtagacctccagaagaaactggaggaattggaattagacgaacaa
caaaagaaacggctcgaggctttcctcacccagaaagccaaggttggggagctgaaggat
gacgactttgagaggatctcggagctgggagctggcaatggcggggtggtcaccaaagta
cagcacaagccctcaggactcatcatggcacggaagctgattcatttagaaatcaagcct
gccattcgtaatcagattatccgtgagctgcaggtccttcatgagtgtaactcaccatac
attgtgggtttctatggagccttctacagtgatggggagatcagtatctgcatggagcac
atggatggtggctccttggatcaggtcttgaaagaagccaaaagaattcctgaggagatc
ttaggaaaagtcagcatagcagttctgcgaggtttagcttatctccgagagaagcatcag
atcatgcaccgagatgtgaaaccttctaacatcctggtcaattcccggggagaaatcaag
ttgtgtgactttggggttagcggccagcttatcgactccatggcaaattcttttgtggga
acacgatcctatatgtctccggagcggttgcaaggcactcattactcagttcagtcggac
atctggagcatgggtctgtcccttgtggagctgtctataggaaggtaccccatcccccca
ccggactctaaggaactggaagcaatatttgggcgtcccgtggtagatggagcagaggga
gaaacccacagcatctcgccacggcccagacccccaggacgcccagtcagtggccacggg
atggacagccggcctgccatggctatctttgaactgctggactatattgttaatgagcca
cctcccaagctgccgcatggagttttcacacaagacttccaggagtttgtaaataaatgc
ttaattaaaaatccagccgaaagggccgatctgaagatgctgatgaaccacaccttcatc
aagcgctcagaggtggaagaggtggattttgctggctggctgtgcaagacgctgcggctc
aaccagcccagcacgcccacccgcacagccatgtga

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