Ailuropoda melanoleuca (giant panda): 100466510
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Entry
100466510 CDS
T01329
Symbol
PSEN2
Name
(RefSeq) presenilin-2
KO
K04522
presenilin 2 [EC:3.4.23.-]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml04330
Notch signaling pathway
aml04722
Neurotrophin signaling pathway
aml05010
Alzheimer disease
aml05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
100466510 (PSEN2)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
100466510 (PSEN2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100466510 (PSEN2)
05022 Pathways of neurodegeneration - multiple diseases
100466510 (PSEN2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
aml01002
]
100466510 (PSEN2)
Peptidases and inhibitors [BR:
aml01002
]
Aspartic peptidases
Family A22: presenilin family
100466510 (PSEN2)
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Gene cluster
GFIT
Motif
Pfam:
Presenilin
Peptidase_A22B
Motif
Other DBs
NCBI-GeneID:
100466510
NCBI-ProteinID:
XP_034523526
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All DBs
Position
8:65176499..65197021
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AA seq
462 aa
AA seq
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MLTFMASDSEEEVCDERTSLMSAESPPPRCCQEARQGLEDGGNAAQWRSQDSEDDLDEDA
DRYMCGGVPGQPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLS
EMFYFRVLSPHTSPEGLLDLPISLSAGCAGAMLRSPRPGGLAGPVAVARPLGAAGQQRPG
FIHGWLIMSSLMLLFLFSYIYLGEVLKTYNVAMDYPTLFLTVWNFGAVGMVCIHWKGPLV
LQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNE
PIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLPG
YPGEELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLL
AVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
atgctcacattcatggcctctgacagtgaggaagaagtgtgtgacgagaggacgtccctg
atgtcggccgagagccccccgccgcgctgctgccaggaggcccggcagggcctggaggac
ggaggcaatgctgcccagtggagaagccaggatagcgaggacgaccttgacgaggacgcg
gaccgctacatgtgcggtggggtccccgggcagccgtcgggcctggaggaggagctgacc
ctcaaatacggggcgaagcacgtgatcatgctgtttgtgcccgtcaccctgtgcatgatc
gtggtggtggccaccatcaagtccgtgcgcttctacacagagaagaacggccagctaagc
gagatgttctattttagggtcctttcaccccacacttcccctgagggtttactcgacctt
cctatttccctctcggctggctgtgcaggtgccatgctgaggtctccgaggcctgggggc
ctggcgggccctgtagctgtggcgaggcccctgggagccgcaggacagcagcggcccggg
ttcatccatggctggctgatcatgtcttccctgatgctgctgttcctcttttcctatatc
tacctcggggaagtgctcaagacctacaacgtggccatggactaccccaccctgttcctg
accgtctggaacttcggcgcggtggggatggtgtgcatccactggaaaggccccctggtg
ctgcagcaggcctacctcattatgatcagcgcgctcatggccttggtcttcatcaagtac
ctcccggagtggtccgcctgggtcattctgggcgccatctctgtgtatgatctcgtggct
gtgctgtgccccaaagggccactgaggatgctggtggagactgcccaggagagaaacgag
cccatatttcccgccctgatatactcctctgccatggtgtggacggtgggcatggccaag
ctggacccctcctcccagggagcccttcagctgccctatgaccctgagatggaagaagac
tcctatgacagttttggggagccctcttacccggaagtctttgagccccccttgcctggt
tacccaggagaggagctggaggaagaggaagaaaggggcgtgaagctcggcctgggggac
ttcatcttctacagtgtgctggtgggcaaggcggcggccacgggcagcggggactggaac
accacgctggcatgcttcgtggccatcctaattggtttgtgtctgaccctcctgctgctt
gctgtgttcaagaaggcactgcccgccctccccatctccatcacgttcgggctcatcttc
tacttttccacggacaacctggtgcgtccgttcatggacaccttggcttctcatcagctc
tacatctga
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