| Entry |
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| Symbol |
HSD17B4
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| Name |
(RefSeq) peroxisomal multifunctional enzyme type 2
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| KO |
| K12405 | (3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.- 4.2.1.107 4.2.1.119] |
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| Organism |
aml Ailuropoda melanoleuca (giant panda)
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| Pathway |
| aml01040 | Biosynthesis of unsaturated fatty acids |
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| Module |
| aml_M00862 | beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA |
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| Brite |
KEGG Orthology (KO) [BR:aml00001]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
100471749 (HSD17B4)
01040 Biosynthesis of unsaturated fatty acids
100471749 (HSD17B4)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
100471749 (HSD17B4)
Enzymes [BR:aml01000]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.107 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
100471749 (HSD17B4)
4.2.1.119 enoyl-CoA hydratase 2
100471749 (HSD17B4)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
3:10608804..10701091
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| AA seq |
737 aa
MASPLRFDRRVVLVTGAGGGLGRAYALAFAERGASVVVNDLGGDMKGLSKGSLAAADKVV
EEIRSKGGKAVANYDSVEAGEKLVRTALEAFGRIDVVVNNAGILRDNSFARISDEDWDII
HRVHLRGSFQVTRAAWEHMKKQKFGRIVMTASASGIYGNFGQANYSAAKLGLLGLSNTLA
VEGQKCNIHCNTIAPAAGSRMTQSIMTEDLVEALKPDYVAPLVLWLCHESCEENGSLFEV
GGGWIGKLRWERALGAIVRQKNQPMTPEAVKANWQKICDFENASKPLSIQESIGSIIGVL
SKIDSEGGISTNRTSHEASADPSAFAEIIGHKLPPFYSAYTELQTIMYALGVGASMKEPK
DMKFLYEGSTDFSCLPTFGVVLAQKPIIGRDLPEFPGVSVNLGKALHGEQYLELHKPLPR
SGNLKCEAVIVDVLDKVSGLVILLDVYSYLEEELVCYNQFSVFFVGSGGIGGKRVSDKAK
VAVPVPNRPPDAVRSEVTSVNQSALYRLSGDWNPLHIDPNLAGFAGFDRPILHGLCTFGF
SARHVLQQFGDNDVLRFKAIKARFAKPVYPGQTLQTDMWKEGNRIHFQTKVQETGDIVIS
NAYVDLLPTSEISAKPLSEGGELQSTLVFEEIGRRLEDIGHEVAKKVNAVFEWHITKGGH
TAAKWTIDLKSGSGKVYQGPAKGSADATFTLSDEDFMEVVLGKLDPQKAFFSGRLKASGN
IMLSQKLQMILKDYAKL |
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| NT seq |
2214 nt +upstreamnt +downstreamnt
atggcctcgccgctgcgattcgacaggcgggtggtactggtcaccggcgcggggggagga
ctgggccgagcctatgccctggcttttgcagaaagaggtgcatctgttgttgtgaatgac
ttaggaggggacatgaagggattgagtaaaggctccttggcagctgctgacaaggttgtt
gaagaaataagaagtaaaggtggaaaagccgtggccaactatgattcagtggaagcagga
gagaagcttgtgaggacagcactagaagcttttggaagaatagatgttgtggtcaacaat
gctgggattctgagggacaattcttttgctaggataagtgacgaagattgggatataatc
cacagagtccatttgcgaggctcgttccaagtgacccgggcagcttgggagcatatgaag
aagcagaagtttggaaggattgttatgacggcatcagcttcaggaatatatggcaacttt
ggccaggccaattacagtgctgcaaagctgggtcttctgggcctttcaaatacccttgca
gttgaaggccagaaatgcaacattcattgtaacactattgcccctgctgctggatcacgg
atgacccaaagcattatgactgaagatctcgtggaagctctgaagccagattatgtggcc
cccctggtcctttggctttgccatgagagctgtgaggaaaatggtagcttgtttgaggtt
ggaggaggatggattggaaaactacgctgggagcgggcccttggagccattgtgagacag
aagaatcagcccatgactcctgaggccgtgaaggccaactggcagaagatctgtgacttc
gagaatgccagcaagcccctgagcattcaagaatcaattggcagtataattggagttcta
agtaaaatagattcagagggaggcatttcgacaaatcgtacgagccacgaagcatcagca
gatccatcggcatttgctgaaattattggccataaacttcctcccttttattctgcttat
acggaactgcaaactattatgtatgcccttggcgtgggagcatcgatgaaggaaccgaaa
gatatgaaattcttatatgaagggagcaccgatttttcctgtttgcctacctttggagtt
gttttagctcagaaacctataataggtagagacttaccagagtttcctggggtttcagtc
aacttgggaaaggctctccacggggagcaatacttggagttacataaaccacttcccaga
tcaggaaacttaaaatgtgaagcagtcattgttgatgtccttgataaagtatccggtcta
gtaattcttctggatgtctattcttacttggaggaggaacttgtatgctataatcagttc
tctgttttctttgttggctctggaggcattggtggaaaacgggtgtcagacaaagccaag
gtagctgtacccgtgcctaatagacctcccgatgctgtccgtagtgaggtcacctcggtt
aatcagtctgctttgtaccgcctcagtggtgactggaatcccttacacattgatcctaac
ctcgctggttttgcaggtttcgacaggcccatattacatggattatgtacatttggattt
tctgccaggcatgttttacagcagtttggagataatgatgtgttgagattcaaggcaatt
aaggctcgtttcgcaaagccagtgtatccaggacagactctacagactgacatgtggaag
gaaggaaatcgaatccatttccaaaccaaggtccaagaaactggagacattgtcatttca
aatgcgtatgtcgatctcctgccgacatctgagatttcagcaaagccactctctgagggt
ggggagctccagagtaccctggtatttgaggagataggtcgccgccttgaggatatcggg
catgaggtggcaaagaaagtaaatgccgtatttgagtggcatatcactaaaggtggacac
actgcagccaagtggactatagacctgaaaagcggttctggaaaagtgtatcaaggccct
gcaaaaggctctgctgacgccaccttcaccctttcagatgaagatttcatggaagtggtc
ctgggcaagcttgaccctcagaaggcattctttagtggcagactgaaggccagcgggaac
atcatgctgagccagaaacttcagatgattcttaaagactatgccaagctctga |
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