KEGG   Ailuropoda melanoleuca (giant panda): 100472337
Entry
100472337         CDS       T01329                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase isoform X1
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml00670  One carbon pool by folate
aml00790  Folate biosynthesis
aml01100  Metabolic pathways
aml01240  Biosynthesis of cofactors
aml01523  Antifolate resistance
aml04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:aml00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    100472337 (DHFR)
   00670 One carbon pool by folate
    100472337 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    100472337 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    100472337 (DHFR)
Enzymes [BR:aml01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     100472337 (DHFR)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 100472337
NCBI-ProteinID: XP_002916264
Ensembl: ENSAMEG00000015750
UniProt: G1MB80
LinkDB
Position
3:complement(55300880..55320970)
AA seq 187 aa
MVRTLNCIAAVSQNMGIGKNGDLPWPPLRNEFKFFQRMTTTSSVEGKQNLVIMGRKTWFS
IPEKNRPLKDRINLVLSRDLKEPPQGAHFLAKSLDDALKLIEQPELANKVDIVWIVGGSS
VYKEAMNKPGHLRLFVTRIMQEFESDTFFPEIDLDKYKLLPEYPGVPSDVQEEKGIKYKF
EVYEKND
NT seq 564 nt   +upstreamnt  +downstreamnt
atggttcgtacgctaaactgcatcgccgctgtgtcccagaacatgggcatcggcaagaac
ggggacctgccctggcccccgctcaggaatgaattcaagtttttccaaagaatgaccaca
acctcctcagtagaagggaaacagaatttggtgattatgggtaggaagacatggttctct
attcctgagaagaatcgacctttaaaggacagaattaatttagttctcagcagagacctc
aaggaacctccacaaggagctcattttcttgccaaaagtctggatgatgccttaaaactt
attgagcaaccagaattagcaaataaagtggacatagtttggatagtgggaggcagttct
gtttataaggaagccatgaacaaaccaggccatcttagactatttgtgacaaggattatg
caggaatttgaaagtgacacattttttccagaaattgatttggacaaatacaaacttctg
ccagaatacccaggtgttccttctgatgtccaggaggagaaaggcattaagtacaaattt
gaagtatatgagaagaacgattaa

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