Ailuropoda melanoleuca (giant panda): 100473195 Help Entry 100473195         CDS       T01329                                  Symbol ADCY2 Name (RefSeq) adenylate cyclase type 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism aml  Ailuropoda melanoleuca (giant panda) Pathway aml00230   Purine metabolism aml01100   Metabolic pathways aml01522   Endocrine resistance aml04015   Rap1 signaling pathway aml04020   Calcium signaling pathway aml04022   cGMP-PKG signaling pathway aml04024   cAMP signaling pathway aml04062   Chemokine signaling pathway aml04072   Phospholipase D signaling pathway aml04081   Hormone signaling aml04082   Neuroactive ligand signaling aml04114   Oocyte meiosis aml04211   Longevity regulating pathway aml04213   Longevity regulating pathway - multiple species aml04261   Adrenergic signaling in cardiomyocytes aml04270   Vascular smooth muscle contraction aml04371   Apelin signaling pathway aml04540   Gap junction aml04611   Platelet activation aml04713   Circadian entrainment aml04714   Thermogenesis aml04723   Retrograde endocannabinoid signaling aml04724   Glutamatergic synapse aml04725   Cholinergic synapse aml04727   GABAergic synapse aml04750   Inflammatory mediator regulation of TRP channels aml04911   Insulin secretion aml04912   GnRH signaling pathway aml04913   Ovarian steroidogenesis aml04914   Progesterone-mediated oocyte maturation aml04915   Estrogen signaling pathway aml04916   Melanogenesis aml04918   Thyroid hormone synthesis aml04921   Oxytocin signaling pathway aml04922   Glucagon signaling pathway aml04923   Regulation of lipolysis in adipocytes aml04925   Aldosterone synthesis and secretion aml04926   Relaxin signaling pathway aml04927   Cortisol synthesis and secretion aml04928   Parathyroid hormone synthesis, secretion and action aml04934   Cushing syndrome aml04935   Growth hormone synthesis, secretion and action aml04970   Salivary secretion aml04971   Gastric acid secretion aml04972   Pancreatic secretion aml04976   Bile secretion aml05032   Morphine addiction aml05163   Human cytomegalovirus infection aml05166   Human T-cell leukemia virus 1 infection aml05200   Pathways in cancer aml05207   Chemical carcinogenesis - receptor activation aml05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:aml00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100473195 (ADCY2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100473195 (ADCY2)    04371 Apelin signaling pathway     100473195 (ADCY2)    04020 Calcium signaling pathway     100473195 (ADCY2)    04072 Phospholipase D signaling pathway     100473195 (ADCY2)    04024 cAMP signaling pathway     100473195 (ADCY2)    04022 cGMP-PKG signaling pathway     100473195 (ADCY2)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     100473195 (ADCY2)    04081 Hormone signaling     100473195 (ADCY2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100473195 (ADCY2)   09144 Cellular community - eukaryotes    04540 Gap junction     100473195 (ADCY2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100473195 (ADCY2)    04062 Chemokine signaling pathway     100473195 (ADCY2)   09152 Endocrine system    04911 Insulin secretion     100473195 (ADCY2)    04922 Glucagon signaling pathway     100473195 (ADCY2)    04923 Regulation of lipolysis in adipocytes     100473195 (ADCY2)    04912 GnRH signaling pathway     100473195 (ADCY2)    04913 Ovarian steroidogenesis     100473195 (ADCY2)    04915 Estrogen signaling pathway     100473195 (ADCY2)    04914 Progesterone-mediated oocyte maturation     100473195 (ADCY2)    04921 Oxytocin signaling pathway     100473195 (ADCY2)    04926 Relaxin signaling pathway     100473195 (ADCY2)    04935 Growth hormone synthesis, secretion and action     100473195 (ADCY2)    04918 Thyroid hormone synthesis     100473195 (ADCY2)    04928 Parathyroid hormone synthesis, secretion and action     100473195 (ADCY2)    04916 Melanogenesis     100473195 (ADCY2)    04925 Aldosterone synthesis and secretion     100473195 (ADCY2)    04927 Cortisol synthesis and secretion     100473195 (ADCY2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100473195 (ADCY2)    04270 Vascular smooth muscle contraction     100473195 (ADCY2)   09154 Digestive system    04970 Salivary secretion     100473195 (ADCY2)    04971 Gastric acid secretion     100473195 (ADCY2)    04972 Pancreatic secretion     100473195 (ADCY2)    04976 Bile secretion     100473195 (ADCY2)   09156 Nervous system    04724 Glutamatergic synapse     100473195 (ADCY2)    04727 GABAergic synapse     100473195 (ADCY2)    04725 Cholinergic synapse     100473195 (ADCY2)    04723 Retrograde endocannabinoid signaling     100473195 (ADCY2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100473195 (ADCY2)   09149 Aging    04211 Longevity regulating pathway     100473195 (ADCY2)    04213 Longevity regulating pathway - multiple species     100473195 (ADCY2)   09159 Environmental adaptation    04713 Circadian entrainment     100473195 (ADCY2)    04714 Thermogenesis     100473195 (ADCY2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100473195 (ADCY2)    05207 Chemical carcinogenesis - receptor activation     100473195 (ADCY2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100473195 (ADCY2)    05163 Human cytomegalovirus infection     100473195 (ADCY2)   09165 Substance dependence    05032 Morphine addiction     100473195 (ADCY2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100473195 (ADCY2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100473195 (ADCY2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100473195 (ADCY2) Enzymes [BR:aml01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100473195 (ADCY2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N HNOBA Motif Other DBs NCBI-GeneID:  100473195 NCBI-ProteinID:  XP_034512990 Ensembl:  ENSAMEG00000028284 UniProt:  A0A7N5KK52 LinkDB All DBs Position 3:complement(141627821..142024305) Genome browser AA seq 997 aa AA seqDB search MSQQHPLIVFLLLIVMGACLALLAVFFALRLDVEDHVAFLITVPTALAIFFAIFILVCIE SVFRKLLRLFSVLIWICLVAMGYLFMCFGGTVSPWDQILANVIIFICGNLAGAYHKHLME LALQQTYQDTCNCIKSRIKLEFEKRQQERLLLSLLPAHIAMEMKAEIIRRLQGPRAGQME NTNNFHNLYVKRHTNVSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMR IKILGDCYYCVSGLPISLPNHAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLC GVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYL KQHLVKTYFVINPKGERRSPHLFRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRD SMTTENGKISTTDVPMGQHNFQNRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSE DIQRISLLFYNKILEKEYRATALPAFKYYVTCACLIFFCIFIVQILVLPKTSILGISFGA AFLLLAFILFICFAGQLLQCSKKASASLLWLLKSSGIIADRPWPRVSLTVLTTAIILTMA VFNMFFLSDPEETIPPTANTSNTSLSALSNQAAILRAQNLFFLPYCIYSCVLGLISCSVF LRVNYELKMLIMMVALVGYNTILLHTHAHVLDDYSQVLFERPGIWKDLKTMGSVSLFIFF VTLLVLGRQNEYYCRLDFLWKNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLK NEELYHQSYDCVCVMFASIPDFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSG VEKIKTIGSTYMAATGLSAVPSQEHAQEPERQYMHIGTMVEFAFALVAKLDAINKHSFND FKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLILQTLG YTCTCRGIINVKGKGELKTYFVNTEMSRSLSQSNLAS NT seq 2994 nt NT seq  +upstreamnt  +downstreamnt atgagccagcagcacccgctcatcgtcttcctgctgctcatcgtcatgggcgcctgcctc gccctgcttgccgtcttcttcgcgctccggctggacgttgaagaccatgtggcattttta atcacggtcccgacagccctggcgatcttctttgcgatattcatcctcgtctgcatcgag tccgtgttcaggaagctgctacgcctcttctctgtgctgatatggatctgcctcgtggcc atgggctacctgttcatgtgcttcggaggcaccgtctctccctgggaccagatcctggcc aatgtgatcattttcatctgtgggaacctggcaggagcataccacaagcacctcatggag ctggccttgcagcagacatatcaggacacctgcaactgtatcaagtctcggatcaagctg gaatttgaaaagcgtcagcaggagcggcttctgctctccctgctgccggctcacatagcc atggaaatgaaagccgagatcatccggaggctgcagggccccagagccggccaaatggaa aacacaaacaacttccacaacctgtatgtcaagcgacataccaacgtgagcatcctgtat gctgatattgttggcttcacccggctggccagtgactgctccccaggagaactggtccac atgctgaacgagctctttggaaagttcgaccaaattgcaaaggagaatgaatgcatgaga ataaaaattttgggagactgctactactgtgtgtccggacttcctatatctctcccgaac catgccaagaactgtgtgaaaatggggctggacatgtgtgaagccataaagaaagtgagg gacgccactggagtggatatcaacatgcgcgtgggagtgcattctgggaacgtcctctgc ggggtgattggtctgcagaagtggcagtatgacgtgtggtcacatgacgttaccttggcc aatcacatggaagctggaggggtccctggacgtgttcacatttcttccgtcaccctggaa cacttgaacggcgcttataaagtggaggaaggagacggtgacatcagagacccatattta aaacagcacctggtgaaaacctactttgtcatcaaccccaagggagaacgaaggagtcct cacctcttcagacctcgccataccctcgatggagccaagatgagggcctctgtgcgcatg acccggtacctggagtcctggggggcggccaagccctttgcacacctgcatcaccgagac agcatgaccacggagaatggcaaaatcagcaccacggatgtgccaatgggtcagcataat tttcaaaatcgtaccttaagaaccaagtcccaaaagaagagatttgaagaagaattaaat gaaaggatgattcaagcaattgatggaattaacgcacaaaagcagtggctcaagtctgaa gacattcagagaatctcactcctgttctacaataaaatactagaaaaagaataccgagcc accgccctgccagcgtttaagtactacgtgacctgcgcatgtctcatattcttctgcatt ttcattgtgcagattctggtgttaccaaaaacgtccattctggggatttcctttggagct gcatttctcttgctcgcctttatcctcttcatctgctttgctggacagcttttgcaatgc agcaagaaggcctccgcctctctcctgtggctgttgaagtcgtcgggcatcatcgcggac cggccctggcctcgtgtctccctcactgtcctcaccacggccatcattctgaccatggcc gtgttcaacatgtttttcctgagtgacccagaggaaacaattcctccaactgccaatacg tccaacacaagtctttctgccttaagtaatcaggcagcgattctacgggcacaaaatctg tttttcctcccgtactgcatctacagctgcgtcctggggctgatctcctgctcggttttc ctgagggtgaattacgagttgaagatgttgatcatgatggtggcgttggtgggctacaac accatccttctacacacgcacgcccacgtcctggacgactacagccaggtcttattcgag agaccaggcatttggaaagacctgaagaccatgggctcagtgtctctctttatattcttc gtcacactgcttgttctgggtagacagaatgaatattactgtaggttagacttcttatgg aagaacaagttcaaaaaagagcgggaggagatagaaaccatggaaaacctgaaccgcgtg ctgctggagaacgtgctgcccgcgcacgtggcggagcatttcctggcccggagcctgaag aacgaggagttataccaccagtcctatgactgtgtctgcgtcatgtttgcctctattccg gatttcaaagaattctacacagaatcagatgtgaacaaggagggcttggagtgccttcgg ctcctgaatgagatcatcgccgactttgatgatctgctgtccaagccgaagttcagtgga gttgaaaagatcaagaccatcggcagcacatacatggcggcgaccggtctgagcgccgtg cccagccaggagcacgcccaggagccggagaggcagtacatgcacattggcaccatggtg gagtttgcctttgcactggtggcgaagctggacgccatcaacaagcactccttcaacgac ttcaagctgcgagtgggtattaaccacggacctgtgatagccggtgtgattggagctcag aaaccgcagtatgatatctggggcaacactgtaaacgtggccagcaggatggacagcacc ggcgtgctggacaagatacaggtcaccgaggagaccagcctcatcctccagaccctgggg tacacgtgcacgtgtcgaggaataatcaatgtgaaaggcaagggggagctgaagacgtac tttgtgaacacagaaatgtcaaggtccctttcccagagcaacttggcatcctga

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