Ailuropoda melanoleuca (giant panda): 100474644
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Entry
100474644 CDS
T01329
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml00061
Fatty acid biosynthesis
aml00620
Pyruvate metabolism
aml00640
Propanoate metabolism
aml01100
Metabolic pathways
aml04152
AMPK signaling pathway
aml04910
Insulin signaling pathway
aml04920
Adipocytokine signaling pathway
aml04922
Glucagon signaling pathway
aml04931
Insulin resistance
aml04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
100474644 (ACACB)
00640 Propanoate metabolism
100474644 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100474644 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
100474644 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
100474644 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100474644 (ACACB)
04922 Glucagon signaling pathway
100474644 (ACACB)
04920 Adipocytokine signaling pathway
100474644 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100474644 (ACACB)
04931 Insulin resistance
100474644 (ACACB)
Enzymes [BR:
aml01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
100474644 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
100474644 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
100474644 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
100474644
NCBI-ProteinID:
XP_019657377
LinkDB
All DBs
Position
12:17186928..17308983
Genome browser
AA seq
2427 aa
AA seq
DB search
MMDSKQVTENKSEGSYIPSQEPFPASDCSGEPPQKNGDRSPLPETPNQAEPASHKGPKDA
CGQRTSRPPPHQNPRSSDDAPAVLQANGAGTEGLRTPDTNGLSSPARPQGQRTRPLSKED
EKQEHLKRQLMTSFVLGSFDDNSSDEDPSAGLFRESSRKGSRASLGTLSLEAALAVGESE
SPVPAMRPSMSGLHLVKRGRELKKVDLHRDFTVASPAEFVTRFGGDRVIEKVLIANNGIA
AVKCMRSVRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPGGPNNNNYAN
VELVVDIAKRIPVQAVWAGWGHASENPKLPELLRKHEIAFLGPPSEAMWALGDKIASTIV
AQTLQIPTLPWSGSGLTVEWAEEDLQRGKRITVPEDVYNQGCVKNIDEGLQMAEKIGFPL
MIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPGSPVFLMKLAEHARHLEVQILADQYG
NAVSLFGRDCSIQRRHQKIIEEAPATIAISVVFEIMEQCAVRLAKTVGYVSTGTVEYLYS
QDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLLYGESPWGVT
PISFDTPANPPLARGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGG
LHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLINLLETERFQNNDI
DTGWLDYLIAEKVQAEKPDIMLGVVCGALNVADAMFRTCMTDFLHSLERGQVLPAASLLN
IVDVELIYGGVKYILKVARQSLTMFVLIMNDCHIEIDAHRLSDGGLLLSYNGNSYTTYMK
EEFDSYRITIGNKTCVFEKENDPTVLRAPSAGKLLQYTVADEGHVEAGSSYAEMEVMKMI
MTLNVQESGRVKYFKRPGAMLEAGCVVARLELDDPSKVHPAKPFTGELPSQQTLPIVGEK
LHQVFHNVLENLTNVMNGYCLPEPIFSTKLKEWVQKLMMALRHPSLPLLELQEIMTSVSG
RVPAPVEKSVRRVMAQYAGNITSVLCQFPSQQIATILDCHAATLQRKAEREVFFMNTQSI
VQLVQRYRSGTRGYMKAVVLDLLRRYLRVEHHFQQAHYDKCVINLREQLKPDMSQVLDCI
FSHAQVAKKNQLVIMLIDELCGPDPSLSEELTSILNELTQLSKSEHCKVALRARQVLIAS
HLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFYHANKVVCMA
SLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFMLPSSHPNRMAVPISVTNPDLLRHST
ELFMDSGFSPLCQRMGAMVAFRRFEDFKRNFDEVISCFANVPQEAPLFSKACTSLYCEED
SKNPREEPIHILNVALQYADHLEDEELVPIFRTFVQSKKNILVDYGLRRITFLIAQEKEF
PKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRSFDLTAVPCANHKMHLYLGAAKVKE
GAEVTDHRFFIRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNNTSVRTDCNH
IFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAEVKINIRQTATGSAAPIRLFI
TNESGYYLDISLYKEVTDPRSGNIMFHSFGNKQGPQHGMLINTPYVTKDLLQAKRFQAQS
LGTTYVYDFPEMFRQALFKLWGTPDKYPKDILTYTELVLDPQGQLVEMNRLPGGNEVGMV
AFKMRFKTPEYPEGRDVIVISNDITFRIGSFGMGEDLLYLRASEMARAEGIPKIYLAANS
GACIGLAEEIKHIFQVAWVDPGDPHKGLKYLYLTPQDYTTISSLNSVHCRHIEEDGESRY
VITDIIGKDSGVGIENLRGSGMIAGESSLAYDEIVTISLVTCRAVGIGAYLVRLGQRVIQ
VENSHIILTGVSALNKVLGREVYTSNNQLGGVQIMHYNGISHITVPDDFEGVCTILEWLS
YMPKDNHSPVPIITPTDPIDREIGFFPTRVPYDPRWLLAGRPHPTLKGSWQSGFFDHGSF
KEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEVVVPADPANLDSEAKIIQQAGQVWLP
DSAYKTAQAIKDFNRERLPLMIFANWRGFSGGMKDMYDQMLKFGAYIVDSLRQYKQPVLI
YIPPSAELRGGSWVVVDSSINPLCIEMYADKESRANILEPEGTVEIKYRKKDLIKTMRRI
DPVYKKLVEQLGMSGLSDKDRKDLEGQLKAREDLLLPVYHQVAVQFADLHDSPTCLLEKG
AISDILEWKTARSFLYWRLRRLLLEDQVKQEILGASRELSHVHIQSMLRRWFVETEGAVK
AYLWDNNQVVVQWLEQHWQGGDSLRSTVRENIKCLKRDSVLKAIRGLVQDNPEVAMDCIA
YISQHVSPAERAQVLHLLSTMDGPAST
NT seq
7284 nt
NT seq
+upstream
nt +downstream
nt
atgatggactctaagcaagtcaccgagaataaatcagaagggagctatatcccaagccag
gagccctttccagcctcagactgctcaggggagccaccacagaaaaatggtgaccgcagc
cctctgccagagactcctaaccaggctgagccagcctcccacaaaggtcccaaagatgcc
tgtgggcaaagaacttccaggccacccccacaccagaacccccgttcctctgatgacgcc
cccgcagtgctccaagccaatggggcggggactgaaggcctgaggaccccggataccaat
ggcctgtcatctccagccaggcctcagggccagcgaaccagaccgctctccaaagaagac
gagaagcaggagcacctcaagaggcagctgatgaccagcttcgtcttgggctcctttgat
gacaactcgtccgatgaggaccccagtgcgggcttgttccgagagtcctcccggaagggc
agccgggccagcctggggaccctgtccctggaggccgccctggctgtaggcgagtccgag
agccccgtccccgctatgagacctagtatgtcgggacttcacctggtgaagaggggccga
gaactgaagaaggtggacctgcacagagactttaccgtggcctccccagctgagtttgtt
acgcgctttgggggggaccgggtcattgagaaggtgctcatcgccaacaatggcatcgcc
gccgtgaagtgcatgcgctccgtccgcaggtgggcctatgagatgttccgcaacgagcgg
gccatccggtttgtagtcatggtgaccccagaggacctgaaggccaatgcagagtatatc
aagatggcagatcagtatgtccctgtcccaggagggcccaacaacaacaattatgccaac
gtggagctggttgtggacattgccaagagaatccccgtgcaggcggtgtgggctggctgg
ggccatgcttctgaaaaccccaaactgccggagctcctgcgcaagcatgagatcgctttc
ttaggccctcccagtgaggccatgtgggccttgggagataagatcgcctccaccattgtg
gcccagacgctgcagatcccaacactgccctggagtggaagcggtctgacggtggaatgg
gcagaagaggatttgcagcgggggaagagaatcactgtcccagaagatgtttacaaccag
ggttgtgtgaaaaatatagatgagggcttacagatggcagaaaaaattggttttcccttg
atgatcaaagcatctgaaggcggcggagggaaaggaatccggaaggcagagagtgccgag
gacttcccaatccttttcagacaagtgcagagtgagatccccggctcccccgtcttcctc
atgaagctagccgagcacgcccgacacctggaggtccagatcctcgccgaccagtatggg
aacgccgtgtccctgttcgggcgtgactgctccatccagcggcggcatcagaagatcatt
gaggaggcgccggccaccatcgccatatcggttgtgttcgagatcatggagcagtgtgcc
gtccgcctggccaagacggtgggctacgtgagcacggggacggtggagtatctctatagc
caggacggcagcttccacttcttggagctgaatccccgcctgcaggtggagcacccctgc
acagagatgatcgccgacgtcaacctgccggccgcccagttacagattgctatgggggtg
cccctgcaccggctgaaggatatccggcttctgtatggagagtcgccgtggggggtgaca
cccatttctttcgacactcctgccaaccctccgctcgcccgaggccatgtcatcgcggct
agaatcaccagtgagaaccccgatgaggggtttaagccaagctctggaacggttcaggag
ctgaatttccggagcaacaagaacgtgtggggttatttcagcgtagcggctgccggcggc
ttacacgagtttgctgattcccagttcgggcactgcttctcctggggagagaaccgggaa
gaggccatttcgaacatggtggtggctttgaaggagctgtccatccggggcgacttcaga
accaccgtggagtatctcattaacctgctggagactgagcgcttccagaacaatgacatc
gacacaggctggttggattacctcatcgccgagaaagtgcaggcggagaagccggatatc
atgctcggggtggtgtgcggagccttgaacgtggccgatgcgatgttcagaacttgcatg
acggatttcttacactcgctggaaaggggccaggtccttcctgcagcttctctgctgaac
atcgtggatgtggaattaatttatggaggtgttaagtacattctcaaggtggcccggcaa
tctctgaccatgttcgtcctcatcatgaacgactgtcacatcgagatcgacgcccaccgg
ctaagcgacggggggttgctgctgtcctataatggtaacagctataccacctacatgaaa
gaagagtttgacagttaccgtattaccatcggcaacaagacgtgtgtgtttgagaaagag
aacgatcccacggtcctgagagccccttcggctgggaagctgcttcagtacacggtggcg
gacgagggccacgttgaggctgggagcagctacgctgagatggaggtgatgaagatgatc
atgaccttgaacgtgcaggaaagtggccgggtgaagtactttaagcgcccgggggccatg
ctggaggcaggctgtgtggtggccaggctggagctcgatgacccttccaaagtgcacccg
gccaagccattcacaggagagctcccttcccagcaaactctgcccatcgtgggagagaaa
ctgcaccaggttttccacaatgtcctggaaaacctgaccaacgtcatgaatggctactgt
ctgccggagcctatttttagcacaaagctgaaggagtgggtacagaagctcatgatggcc
ctccgacacccgtcgctgccgctgctggagctgcaggagatcatgaccagtgtgtccggc
cgcgtccccgcccccgtggagaagtcggtccgcagggtgatggctcagtacgccggcaac
atcacctcggtgctgtgccagttccccagccagcagatagccaccatcctggactgccat
gcggccaccctgcagcggaaggctgaacgggaggtcttcttcatgaacacccagagcatt
gtgcagctggtccagaggtaccgcagcgggacccgcggctacatgaaggcggtggtgttg
gacctcctgcggagatacttgcgggtggagcatcatttccagcaagctcactacgacaag
tgcgtgataaacctcagggagcagctgaagccagacatgtcccaggtgctggactgcatc
ttctcccacgcgcaggtggccaagaagaaccagctggtgatcatgttgattgatgagctc
tgtggcccagacccttccctgtcagaagagctgacctccatcctcaacgagctcactcag
ctgagcaaaagcgagcattgcaaagtggccctcagagccagacaggtcctgatcgcctcc
caccttccgtcctacgagctgaggcacaaccaggtggagtccattttcctgtctgccatc
gacatgtatggccaccagttctgcccagaaaacctcaagaaattaatactctcagaaaca
accatatttgatgtcctgcccactttcttctaccacgctaacaaagtcgtctgcatggca
tccttggaggtttacgtgcggaggggctatatcgcctatgagttaaacagcttgcagcac
cggcagctcccagacggcacctgcgtggtggaattccagttcatgctgccctcctcccac
ccaaacaggatggccgtgcccatcagcgtcaccaaccccgacctgctgaggcacagcacc
gagctcttcatggacagcggcttctccccactgtgccagcggatgggggccatggtcgct
ttcaggagatttgaggacttcaaaaggaacttcgacgaggtcatctcctgctttgccaat
gtgccccaggaagcccccctcttcagcaaggcctgcacttccctgtactgtgaggaagac
agcaagaaccccagagaagagccgatccacatcctgaatgtggccctccagtacgcggac
cacctggaagatgaggagctggtgccgattttccgcacgttcgtacagtccaagaaaaac
atccttgtggattacggactccgaagaatcacattcctgattgcccaagagaaagaattt
cccaagtttttcacgttcagagcaagagacgagttcgcggaagatcgcatttaccgtcac
ctggagcccgccctggccttccagctggagctcagccgcatgcgcagctttgacctgacc
gccgtgccctgcgccaaccacaagatgcacctttacctgggcgccgccaaagtgaaggag
ggcgcggaagtgacggaccaccgcttcttcatccgcgccatcatccgccactcagacctc
gttacaaaggaagcctcctttgagtacctgcagaacgagggtgagcgtctgctcctggag
gccatggacgagctggaggtggcattcaacaacacgagcgtacgcaccgactgcaaccac
atcttcctgaacttcgtgcccaccgtcatcatggacccctccaagatcgaagagtccgtg
cgttccatggttatgcgctatggcagccggctgtggaaactccgggtgctgcaggctgag
gtcaagatcaacatccgccagaccgccactggcagcgctgctcccatccgcctgttcatc
accaatgagtcgggttactacctggacatcagcctctacaaagaagtcaccgaccccaga
tccggaaacatcatgtttcactcctttggcaacaagcagggaccccagcacgggatgcta
atcaacaccccgtatgtcaccaaggatctgctgcaggccaagcggttccaggcccagtcc
ctgggcaccacctacgtctacgacttcccggagatgttcaggcaggctctctttaaattg
tggggcaccccggacaagtaccccaaagacatcctgacatatacggaactcgtgctggac
cctcagggccagctcgtggagatgaaccgccttcctggaggaaatgaggtgggcatggtg
gccttcaaaatgaggttcaagaccccagaatatccggaaggacgggatgtgatcgtcatc
agcaatgacatcacgttccgcattggatcctttggcatgggagaagacctcttgtacctg
cgggcctctgagatggcccgggcagagggtatccccaaaatctacctcgcagccaacagc
ggggcctgtatcggccttgcagaggagatcaagcacatattccaggtggcttgggtggac
ccaggagacccccacaaaggacttaagtacttgtacctgacgccccaagactacaccaca
atcagctccctgaactctgtccattgtagacacatcgaggaagacggggaatccaggtat
gtcatcacggatatcatcgggaaggacagtggtgtgggcatagagaatctcaggggctcc
ggcatgatcgcaggggagtcctccctggcttacgacgagattgtcaccatcagcttggtg
acttgccgagccgtggggatcggggcctacttggtgaggctgggtcagcgagtgatccag
gtggagaactctcacatcatcctgacgggagtcagcgctctcaacaaggtgctgggcaga
gaggtctacacgtccaacaaccagctgggcggcgtgcagatcatgcattacaatggcatc
tcccacatcactgtgccagatgacttcgagggcgtttgtaccatcctggagtggctgtcc
tatatgccaaaggataatcacagcccagtccccatcatcacacccacggaccccattgac
agagaaattggattcttcccgacccgggttccctatgacccccggtggctgctggcagga
aggcctcacccgactctgaagggatcctggcagagtggattctttgaccatggcagtttc
aaggaaatcatggcgccctgggcccagaccgtggtgacaggacgagcaaggctagggggg
atccctgttggcgtgattgccgtggagacgcggaccgtggaggtggtggtgcctgcggac
cctgccaacctggactcagaggccaagataatccagcaggccggccaggtgtggctccca
gactccgcctacaagacggcccaggccatcaaggatttcaaccgagagaggttgcccctg
atgatctttgccaactggagggggttctccggtggcatgaaagacatgtacgaccagatg
ctgaagttcggagcctacatcgtggacagtctcaggcagtacaaacagcctgtcctcatc
tacatcccaccctccgcggagctccgggggggctcctgggtggtcgtggactcctccatc
aaccccctgtgcatagaaatgtacgcggacaaggagagcagggcgaatattctggagccg
gagggaacggtggagattaagtaccgaaagaaagatctgataaagaccatgagaaggatc
gacccagtttacaagaagctcgtggaacagctaggaatgtcggggctctccgacaaggac
cgcaaggacctggagggccagctgaaggcccgggaggacctgctgctgcccgtctaccac
caggtggcggtgcagttcgccgacctccacgacagccccacctgcctgctggagaagggt
gccatctccgacatcctggagtggaagactgcgcgctccttcctgtactggcgcctgcgc
cgcctcctgctggaggaccaggtcaagcaggagatcctgggggccagcagggagctgagc
cacgtgcacatccagtccatgctgcgccgctggttcgtggagacggagggcgccgtcaag
gcctacctgtgggacaacaaccaggtggtggtgcagtggctggaacagcactggcagggg
ggggacagcctgcgctccaccgtccgcgagaacatcaagtgcttgaagcgagactccgtc
ctcaaggccatcagaggcctggttcaggacaaccctgaagtggccatggactgcatcgca
tacataagccagcacgtcagcccagccgagcgggcccaagtccttcacctcctgtccacc
atggatggcccagcctccacctga
DBGET
integrated database retrieval system
