KEGG   ORTHOLOGY: K01946
Entry
K01946                      KO                                     
Symbol
ACACB
Name
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
Pathway
map00061  Fatty acid biosynthesis
map00254  Aflatoxin biosynthesis
map00620  Pyruvate metabolism
map00640  Propanoate metabolism
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map04152  AMPK signaling pathway
map04910  Insulin signaling pathway
map04920  Adipocytokine signaling pathway
map04922  Glucagon signaling pathway
map04931  Insulin resistance
map04936  Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    K01946  ACACB; acetyl-CoA carboxylase / biotin carboxylase 2
   00640 Propanoate metabolism
    K01946  ACACB; acetyl-CoA carboxylase / biotin carboxylase 2
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    K01946  ACACB; acetyl-CoA carboxylase / biotin carboxylase 2
  09110 Biosynthesis of other secondary metabolites
   00254 Aflatoxin biosynthesis
    K01946  ACACB; acetyl-CoA carboxylase / biotin carboxylase 2
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    K01946  ACACB; acetyl-CoA carboxylase / biotin carboxylase 2
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    K01946  ACACB; acetyl-CoA carboxylase / biotin carboxylase 2
   04922 Glucagon signaling pathway
    K01946  ACACB; acetyl-CoA carboxylase / biotin carboxylase 2
   04920 Adipocytokine signaling pathway
    K01946  ACACB; acetyl-CoA carboxylase / biotin carboxylase 2
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K01946  ACACB; acetyl-CoA carboxylase / biotin carboxylase 2
   04931 Insulin resistance
    K01946  ACACB; acetyl-CoA carboxylase / biotin carboxylase 2
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.15  acetyl-CoA carboxytransferase
     K01946  ACACB; acetyl-CoA carboxylase / biotin carboxylase 2
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.14  biotin carboxylase
     K01946  ACACB; acetyl-CoA carboxylase / biotin carboxylase 2
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.2  acetyl-CoA carboxylase
     K01946  ACACB; acetyl-CoA carboxylase / biotin carboxylase 2
Other DBs
RN: R00742
GO: 0003989 0004075
Genes
HSA: 32(ACACB)
PTR: 452219(ACACB)
PPS: 100985999(ACACB)
GGO: 101135848(ACACB)
PON: 100448476(ACACB)
NLE: 100606756(ACACB)
MCC: 706909(ACACB)
MCF: 102116004(ACACB)
CSAB: 103239081(ACACB)
CATY: 105573223(ACACB)
PANU: 101012644(ACACB)
TGE: 112635049(ACACB)
RRO: 104660172(ACACB)
RBB: 108534384(ACACB)
TFN: 117089443(ACACB)
PTEH: 111538813(ACACB)
CJC: 100402980(ACACB)
SBQ: 101037726(ACACB)
CSYR: 103274926(ACACB)
MMUR: 105866938(ACACB)
OGA: 100959432(ACACB)
MMU: 100705(Acacb)
MCAL: 110294922(Acacb)
MPAH: 110312771(Acacb)
RNO: 116719(Acacb)
MCOC: 116068218(Acacb)
MUN: 110547269 110547283
CGE: 100753124(Acacb)
PLEU: 114681306(Acacb)
NGI: 103746695(Acacb)
HGL: 101717399(Acacb)
CPOC: 100728089(Acacb)
CCAN: 109690552(Acacb)
DORD: 105984210(Acacb)
DSP: 122102681(Acacb)
NCAR: 124990202
OCU: 100339362(ACACB)
OPI: 101529798(ACACB)
TUP: 102480265(ACACB)
CFA: 100685468(ACACB)
VVP: 112910485(ACACB)
VLG: 121475814(ACACB)
AML: 100474644(ACACB)
UMR: 103678344(ACACB)
UAH: 113267083(ACACB)
UAR: 123788217(ACACB)
ELK: 111156399
LLV: 125081691
MPUF: 101681819(ACACB)
ORO: 101365780(ACACB)
EJU: 114219120(ACACB)
ZCA: 113912480(ACACB)
MLX: 118018582(ACACB)
FCA: 101086680(ACACB)
PYU: 121010188(ACACB)
PBG: 122470345(ACACB)
PTG: 102963315(ACACB)
PPAD: 109277478(ACACB)
AJU: 106979653(ACACB)
HHV: 120237339(ACACB)
BTA: 515338(ACACB)
BOM: 102275206(ACACB)
BIU: 109571092(ACACB)
BBUB: 102404793(ACACB)
CHX: 102178200(ACACB)
OAS: 101114816(ACACB)
ODA: 120871398(ACACB)
CCAD: 122422201
SSC: 100154993(ACACB)
CFR: 102512242(ACACB)
CBAI: 105075668(ACACB)
CDK: 105105357(ACACB)
VPC: 102524937(ACACB)
BACU: 103020229(ACACB)
LVE: 103089998(ACACB)
OOR: 101272632(ACACB)
DLE: 111162815(ACACB)
PCAD: 102992865(ACACB)
PSIU: 116765119(ACACB)
ECB: 100066740(ACACB)
EPZ: 103551425(ACACB)
EAI: 106848074(ACACB)
MYB: 102239000(ACACB)
MYD: 102759463(ACACB)
MMYO: 118678332(ACACB)
MLF: 102439451(ACACB)
MNA: 107533881(ACACB)
PKL: 118725382(ACACB)
HAI: 109386154(ACACB)
DRO: 112310890(ACACB)
SHON: 118991210(ACACB)
AJM: 119057414(ACACB)
PDIC: 114509274(ACACB)
PHAS: 123822289(ACACB)
MMF: 118639830(ACACB)
RFQ: 117017281(ACACB)
PALE: 102887451(ACACB)
PGIG: 120601871(ACACB)
PVP: 105303961(ACACB)
RAY: 107500131(ACACB)
MJV: 108399878(ACACB)
TOD: 119244882(ACACB)
SARA: 101546832(ACACB)
LAV: 100657186(ACACB)
TMU: 101351597
DNM: 101426352(ACACB)
GAS: 123256906(ACACB)
SHR: 100932425(ACACB)
PCW: 110222829(ACACB)
OAA: 100076923(ACACB)
GGA: 430557(ACACB)
PCOC: 116228545(ACACB)
MGP: 100539060(ACACB)
CJO: 107321488(ACACB)
NMEL: 110406566(ACACB)
ACYG: 106031086(ACACB)
AFUL: 116496348(ACACB)
TGU: 100222747(ACACB)
LSR: 110478192(ACACB)
SCAN: 103818295(ACACB)
PMOA: 120509538(ACACB)
OTC: 121338832(ACACB)
PRUF: 121364815(ACACB)
GFR: 102045244(ACACB)
FAB: 101819106(ACACB)
PHI: 102104651(ACACB)
PMAJ: 107211484(ACACB)
CCAE: 111936444(ACACB)
CCW: 104688808(ACACB)
ETL: 114062660(ACACB)
ZAB: 102071196(ACACB)
FPG: 101913090(ACACB)
FCH: 102057711(ACACB)
CLV: 102094512(ACACB)
EGZ: 104123683(ACACB)
NNI: 104019168(ACACB)
ACUN: 113486251(ACACB)
TALA: 104361116(ACACB)
PADL: 103925656(ACACB)
ACHC: 115346453(ACACB)
AAM: 106487455(ACACB)
AROW: 112963361(ACACB)
NPD: 112945200(ACACB)
DNE: 112991862(ACACB)
ASN: 102388393(ACACB)
AMJ: 102565973(ACACB)
CPOO: 109312689(ACACB)
GGN: 109290535(ACACB)
PSS: 102461239(ACACB)
CMY: 102942822(ACACB)
CPIC: 101941488(ACACB)
TST: 117888262(ACACB)
CABI: 116839462(ACACB)
MRV: 120386003(ACACB)
ACS: 100566852(acacb)
PVT: 110083411(ACACB)
SUND: 121916415(ACACB)
PBI: 103057144(ACACB)
PMUR: 107287268(ACACB)
PGUT: 117672279(ACACB)
VKO: 123028590(ACACB)
PMUA: 114581463(ACACB)
ZVI: 118094218(ACACB)
GJA: 107112178(ACACB)
XLA: 108715603
XTR: 100192373(acacb)
NPR: 108790508(ACACB)
RTEM: 120938141(ACACB)
BBUF: 120988859(ACACB)
BGAR: 122924353(ACACB)
DRE: 556236(acacb)
SRX: 107752147
SANH: 107684993
SGH: 107597297
CCAR: 109079488 109092869(acacb)
CAUA: 113048915 113096061(acacb)
IPU: 108255442(acacb)
PHYP: 113524973(acacb)
SMEO: 124380419(acacb)
TFD: 113656619
AMEX: 103026070
EEE: 113589900
TRU: 101077743(acacb)
TNG: GSTEN00029540G001
LCO: 104921250(acacb)
NCC: 104945029(acacb)
CGOB: 115012970(acacb)
ELY: 117252866(acacb)
PLEP: 121944662(acacb)
SLUC: 116056576(acacb)
ECRA: 117944549(acacb)
PFLV: 114555987(acacb)
GAT: 120830227(acacb)
PPUG: 119224780(acacb)
MSAM: 119892400(acacb)
CUD: 121510493(acacb)
MZE: 101477909(acacb)
ONL: 100711220(acacb)
OAU: 116332374(acacb)
OLA: 101171338(acacb)
OML: 112147886(acacb)
XMA: 102217269(acacb)
XCO: 114154254(acacb)
XHE: 116729438(acacb)
PRET: 103470346(acacb)
PFOR: 103142895(acacb)
PLAI: 106944558(acacb)
PMEI: 106918451(acacb)
GAF: 122828188(acacb)
CVG: 107100048
CTUL: 119786620(acacb)
GMU: 124877619(acacb)
NFU: 107393958(acacb)
KMR: 108234549(acacb)
ALIM: 106521707
NWH: 119413964(acacb)
AOCE: 111568287(acacb)
CSEM: 103397308
POV: 109638102(acacb)
SSEN: 122769173(acacb)
HHIP: 117767659(acacb)
LCF: 108878118(acacb)
SDU: 111228114(acacb)
SLAL: 111660366(acacb)
XGL: 120805566(acacb)
HCQ: 109510822(acacb)
BPEC: 110156685(acacb)
MALB: 109956888(acacb)
SASA: 106580110(acacb) 106585658
OTW: 112248237 112263291(acacb)
OMY: 110525352 110535755
OGO: 124034566 124036038
ONE: 115111329 115139760
SALP: 111957851 111974209
SNH: 120050553 120063072
ELS: 105014434(acacb)
SFM: 108932552(acacb)
PKI: 111854891(acacb)
AANG: 118237551(acacb)
LOC: 102687665(acacb)
PSPA: 121307729
ARUT: 117426575 117428031
LCM: 102353666(ACACB)
CMK: 103184024(acacb)
RTP: 109937888(acacb)
OLU: OSTLU_11
OTA: OT_ostta10g03450
BPG: Bathy11g03860
MIS: MICPUN_104872
MPP: MICPUCDRAFT_16401
 » show all
Reference
PMID:19190759
  Authors
Castle JC, Hara Y, Raymond CK, Garrett-Engele P, Ohwaki K, Kan Z, Kusunoki J, Johnson JM
  Title
ACC2 is expressed at high levels in human white adipose and has an isoform with a novel N-terminus [corrected].
  Journal
PLoS One 4:e4369 (2009)
DOI:10.1371/journal.pone.0004369
  Sequence
[hsa:32]
Reference
PMID:16854592
  Authors
Cheng D, Chu CH, Chen L, Feder JN, Mintier GA, Wu Y, Cook JW, Harpel MR, Locke GA, An Y, Tamura JK
  Title
Expression, purification, and characterization of human and rat acetyl coenzyme A carboxylase (ACC) isozymes.
  Journal
Protein Expr Purif 51:11-21 (2007)
DOI:10.1016/j.pep.2006.06.005
  Sequence
[hsa:32]
LinkDB

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