Ailuropoda melanoleuca (giant panda): 100477981
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Entry
100477981 CDS
T01329
Symbol
LCK
Name
(RefSeq) tyrosine-protein kinase Lck isoform X2
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
aml
Ailuropoda melanoleuca (giant panda)
Pathway
aml04064
NF-kappa B signaling pathway
aml04380
Osteoclast differentiation
aml04517
IgSF CAM signaling
aml04650
Natural killer cell mediated cytotoxicity
aml04658
Th1 and Th2 cell differentiation
aml04659
Th17 cell differentiation
aml04660
T cell receptor signaling pathway
aml05135
Yersinia infection
aml05166
Human T-cell leukemia virus 1 infection
aml05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
aml05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
aml00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
100477981 (LCK)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
100477981 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100477981 (LCK)
04660 T cell receptor signaling pathway
100477981 (LCK)
04658 Th1 and Th2 cell differentiation
100477981 (LCK)
04659 Th17 cell differentiation
100477981 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
100477981 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100477981 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100477981 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
100477981 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
100477981 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
aml01001
]
100477981 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
aml03036
]
100477981 (LCK)
Enzymes [BR:
aml01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100477981 (LCK)
Protein kinases [BR:
aml01001
]
Non-receptor tyrosine kinases
SRC family
100477981 (LCK)
Chromosome and associated proteins [BR:
aml03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
100477981 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
SH2_1
Haspin_kinase
DUF7251
SH3_16
SH3_3
Motif
Other DBs
NCBI-GeneID:
100477981
NCBI-ProteinID:
XP_002921912
Ensembl:
ENSAMEG00000007672
LinkDB
All DBs
Position
2:10642543..10665542
Genome browser
AA seq
509 aa
AA seq
DB search
MGCSCSSNPEDDWMENIDVCENCHYPIVPLDGKATLPIRNGSDVRDPLVTYEGSNPPASP
LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKAN
SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH
YKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWWEDEWEV
PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL
VRLYAVVTQEPIYIITEYMENGSLVDFLKTPPGIKLTINKLLDMAAQIAEGMAFIEERNY
IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK
SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYHLMMLCWKER
PEERPTFDYLRSVLEDFFTATEGQYQPQP
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtagctgcagctcaaaccccgaagatgactggatggaaaacatcgatgtttgt
gagaactgccattaccccatagtcccactggatggcaaggccacgctgcccatccggaat
ggctctgatgtgcgggatccactggttacctacgaaggctccaaccccccggcctcaccc
ttgcaagacaacctggttatcgctctgcacagctatgagccctctcacgatggagacttg
ggcttcgagaagggtgaacagctccgcatcctggagcagagcggcgagtggtggaaggca
cagtccctgaccacgggccaggaaggtttcattcccttcaacttcgtggccaaagcgaac
agcctagagcccgaaccctggttcttcaagaacctgagccgcaaggacgctgagcggcag
ctcctggcgcccgggaacacgcacggctccttcctgatccgggaaagcgagagcaccgcg
ggatcgttttcactgtccgtgcgggacttcgaccagaaccagggagaggtggtaaaacat
tacaaaatccgtaacctggacaacggcggcttctacatctcccctcgcatcacttttcct
ggcctgcacgagctggtccgccattacaccaatgcttcggacgggctgtgcacgcggttg
agtcgcccctgccagacccagaagccccagaagccttggtgggaggacgagtgggaggtt
cccagggagacgctgaagctggtggagcggctgggagctggccagttcggggaggtgtgg
atggggtactacaacgggcacacaaaggtggcagtgaagagcctgaagcagggcagcatg
tcccccgacgccttcctggcggaggccaacctcatgaagcagctgcaacaccagagactg
gtccggctctacgcggtggtcacccaggagcccatctacatcatcacggaatacatggag
aacgggagcctggtggatttcctcaagacccccccgggcatcaagctgaccatcaacaaa
ctcttggatatggcagcccaaattgcagagggcatggcattcattgaagagcggaattat
atccaccgtgacctgagggctgccaacatcctggtgtctgacaccctgagctgcaagatc
gcagactttggcctagcacgcctcatcgaggacaacgagtacacagccagggagggagcc
aagtttcccattaagtggacagcaccagaagccattaactatgggacgttcaccatcaag
tcggatgtgtggtcttttgggatcctgctgacggagattgtcacccatggccgcatccct
tacccagggatgaccaatcccgaggtgatccagaacctggagcgaggctaccgcatggtg
cgacctgacaactgtccggaggagttgtaccatctcatgatgttgtgctggaaggagcgc
cccgaggaacggcccaccttcgactacctgcgcagtgtgctggaggacttcttcacagcc
acggagggccagtaccagccccagccctga
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