KEGG   Amycolatopsis mediterranei S699: RAM_20935
Entry
RAM_20935         CDS       T01822                                 
Name
(GenBank) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
amn  Amycolatopsis mediterranei S699
Pathway
amn00670  One carbon pool by folate
amn00790  Folate biosynthesis
amn01100  Metabolic pathways
amn01240  Biosynthesis of cofactors
amn04981  Folate transport and metabolism
Module
amn_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:amn00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    RAM_20935
   00670 One carbon pool by folate
    RAM_20935
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    RAM_20935
Enzymes [BR:amn01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     RAM_20935
SSDB
Motif
Pfam: DHFR_1 US2
Other DBs
NCBI-ProteinID: AEK42667
UniProt: A0A9R0NXY2
LinkDB
Position
4509364..4509822
AA seq 152 aa
MIGLVWAQAANGVIGRDGELPWHLPEDLRHFKELTAGAAVVMGRRTWESLPPRFRPLPGR
RNLVLSGTPQEGAETFADLPSALAAVPGDRWVIGGAAVYRAALPFADRIVVTEIRESFEG
DTYAPEVGRPADSVGEWLESSAGLHYRFLTWG
NT seq 459 nt   +upstreamnt  +downstreamnt
gtgatcgggctggtctgggcgcaggcggcgaacggggtcatcggacgggacggcgagctg
ccctggcacctgccggaggacctgcggcacttcaaggagctgaccgcgggggcggcggtg
gtgatgggccgccgcacgtgggagtcgctgccgccgcgcttccggccgctgccggggcgg
cgcaacctcgtgctctcggggaccccgcaggagggcgccgagacgttcgcggacctgccg
tcggcgctcgccgcggtgcccggcgaccggtgggtgatcggcggcgcggcggtgtaccgg
gcggcgctgccgttcgcggaccggatcgtggtcacggagatccgggagtccttcgagggg
gacacgtacgcgccggaggtcgggcggccggcggactccgtgggggagtggctggagtcc
tcggccgggctgcactaccgcttcctgacctggggctga

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